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Invitrogen
Human IL-13 Recombinant Protein
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Product Details
BMS351
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
Human IL-13 recombinant protein contains 114 amino acids
Molecular weight
12.5 kDa
Class
Recombinant
Type
Protein
Purity
>95%
Conjugate
Form
Lyophilized
Purification
purified
Storage buffer
PBS, pH 7.2
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Description: Interleukin-13 is an immunoregulatory protein produced by activated T-lymphocytes. The biological activities of IL-13 include the stimulation of B cell proliferation and immunoglobulins production. Recombinant human IL-13 is a 12.5 kDa protein containing 114 amino acid residues.
Purity: >95%.
Molecular Weight: 12.5 kDa.
Target Information
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ALRH; ALRH antibody; BHR1; il 13; IL-13; ILN; Interleukin; Interleukin-13; Interleukin13; MGC116786; MGC116788; MGC116789; NC30 antibody; P600 antibody
Gene Aliases: IL-13; IL13; NC30; P600
UniProt ID: (Human) P35225
Entrez Gene ID: (Human) 3596
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