Product References
Genomic characterization and therapeutic utilization of IL-13-responsive sequences in asthma.
Cell genomics
Koh KD,Bonser LR,Eckalbar WL,Yizhar-Barnea O,Shen J,Zeng X,Hargett KL,Sun DI,Zlock LT,Finkbeiner WE,Ahituv N,Erle DJ
200-17 was used in In vitro experiments to provide a catalog of cell type-specific genes and regulatory elements involved in IL-13 bronchial epithelial response and showcases their use for therapeutic purposes.
Wed Jan 11 00:00:00 EST 2023
MiR-125a-3p alleviates hyperproliferation of keratinocytes and psoriasis-like inflammation by targeting TLR4/NF-κB pathway.
Postepy dermatologii i alergologii
Jin Z,Huang Q,Peng J,Liu Z,Hu R,Wu J,Wang F
200-17 was used in Cell Culture to show reduced microRNA miR-125a-3p expression in psoriasis patients, psoriasis-like inflammatory cell models, and IMQ-generated psoriasis-like mouse models.
Thu Jun 01 00:00:00 EDT 2023
Early human lung immune cell development and its role in epithelial cell fate.
Science immunology
Barnes JL,Yoshida M,He P,Worlock KB,Lindeboom RGH,Suo C,Pett JP,Wilbrey-Clark A,Dann E,Mamanova L,Richardson L,Polanski K,Pennycuick A,Allen-Hyttinen J,Herczeg IT,Arzili R,Hynds RE,Teixeira VH,Haniffa M,Lim K,Sun D,Rawlins EL,Oliver AJ,Lyons PA,Marioni JC,Ruhrberg C,Tuong ZK,Clatworthy MR,Reading JL,Janes SM,Teichmann SA,Meyer KB,Nikolić MZ
200-17 was used in In vitro experiments to profile human embryonic and foetal lung immune cells using scRNA-seq, smFISH, and immunohistochemistry to find that IL-1β drives epithelial progenitor exit from self-renewal and differentiation to basal cells in vitro.
Fri Dec 15 00:00:00 EST 2023
Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis.
JID innovations : skin science from molecules to population health
Niehues H,Rikken G,van Vlijmen-Willems IMJJ,Rodijk-Olthuis D,van Erp PEJ,Zeeuwen PLJM,Schalkwijk J,van den Bogaard EH
200-17 was used in In vitro experiments to investigate the mitogens involved in keratinocyte proliferation and stratification.
Sat Jan 01 00:00:00 EST 2022
IL-33 Enhances ACE2 Expression on Epidermal Keratinocytes in Atopic Dermatitis: A Plausible Issue for SARS-CoV-2 Transmission in Inflamed Atopic Skin.
Biomedicines
Lin EC,Hong CH
200-17 was used in Sample Preparation (FC/FACS) to reveal that IL-33 enhances ACE2 expression on keratinocytes via ERK.
Fri May 20 00:00:00 EDT 2022
Activated and nonactivated MSCs increase survival in humanized mice after acute liver injury through alcohol binging.
Hepatology communications
Hernandez JC,Yeh DW,Marh J,Choi HY,Kim J,Chopra S,Ding L,Thornton M,Grubbs B,Makowka L,Sher L,Machida K
Fri Jul 01 00:00:00 EDT 2022
Early IL-17A Prevention Rather Than Late IL-17A Neutralization Attenuates Toluene Diisocyanate-Induced Mixed Granulocytic Asthma.
Allergy, asthma & immunology research
Chen S,Yu L,Deng Y,Liu Y,Wang L,Li D,Yang K,Liu S,Tao A,Chen R
200-17 was used in In vitro experiments to demonstrate that IL-17A was required for the initiation of TDI-induced asthma, but functioned as a negative regulator of established allergic inflammation, suggesting that early abrogation of IL-17A signaling, but not late IL-17A neutralization, may prevent the progression of TDI-induced asthma and could be used as a therapeutic strategy for severe asthmatics in clinical settings.
Thu Sep 01 00:00:00 EDT 2022
Network Pharmacology Analysis and Experimental Validation to Investigate the Mechanism of Total Flavonoids of Rhizoma Drynariae in Treating Rheumatoid Arthritis.
Drug design, development and therapy
Chen GY,Luo J,Liu Y,Yu XB,Liu XY,Tao QW
200-17 was used in Cell Culture to indicate that the treatment of RA with TFRD is closely related to inhibiting Th17 differentiation and inflammatory response of synoviocytes.
Thu Jun 16 00:00:00 EDT 2022
Calcium/calmodulin-dependent protein kinase IV promotes imiquimod-induced psoriatic inflammation via macrophages and keratinocytes in mice.
Nature communications
Yong L,Yu Y,Li B,Ge H,Zhen Q,Mao Y,Yu Y,Cao L,Zhang R,Li Z,Wang Y,Fan W,Zhang C,Wang D,Luo S,Bai Y,Chen S,Chen W,Liu M,Shen J,Sun L
200-17 was used in Cell Culture to investigate CaMK4 expression in psoriasis.
Fri Jul 22 00:00:00 EDT 2022
IL-17A Promotes Epithelial ADAM9 Expression in Cigarette Smoke-Related COPD.
International journal of chronic obstructive pulmonary disease
Li D,Wang T,Ma Q,Zhou L,Le Y,Rao Y,Jin L,Pei Y,Cheng Y,Huang C,Gai X,Sun Y
200-17 was used in Cell Culture to reveal a novel role of IL-17A in CS-related COPD, where IL-17A contributes to ADAM9 expression by activating JNK signaling.
Mon Oct 24 00:00:00 EDT 2022
BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection.
Cell
Mills RJ,Humphrey SJ,Fortuna PRJ,Lor M,Foster SR,Quaife-Ryan GA,Johnston RL,Dumenil T,Bishop C,Rudraraju R,Rawle DJ,Le T,Zhao W,Lee L,Mackenzie-Kludas C,Mehdiabadi NR,Halliday C,Gilham D,Fu L,Nicholls SJ,Johansson J,Sweeney M,Wong NCW,Kulikowski E,Sokolowski KA,Tse BWC,Devilée L,Voges HK,Reynolds LT,Krumeich S,Mathieson E,Abu-Bonsrah D,Karavendzas K,Griffen B,Titmarsh D,Elliott DA,McMahon J,Suhrbier A,Subbarao K,Porrello ER,Smyth MJ,Engwerda CR,MacDonald KPA,Bald T,James DE,Hudson JE
Thu Apr 15 00:00:00 EDT 2021
Selenium-GPX4 axis protects follicular helper T cells from ferroptosis.
Nature immunology
Yao Y,Chen Z,Zhang H,Chen C,Zeng M,Yunis J,Wei Y,Wan Y,Wang N,Zhou M,Qiu C,Zeng Q,Ong HS,Wang H,Makota FV,Yang Y,Yang Z,Wang N,Deng J,Shen C,Xia Y,Yuan L,Lian Z,Deng Y,Guo C,Huang A,Zhou P,Shi H,Zhang W,Yi H,Li D,Xia M,Fu J,Wu N,de Haan JB,Shen N,Zhang W,Liu Z,Yu D
Wed Sep 01 00:00:00 EDT 2021
Galectin-8 Is Upregulated in Keratinocytes by IL-17A and Promotes Proliferation by Regulating Mitosis in Psoriasis.
The Journal of investigative dermatology
Lo YH,Li CS,Chen HL,Chiang CY,Huang CC,Tu TJ,Lo TH,Choy DF,Arron JR,Chen HY,Liu FT
200-17 was used in Cell Culture to demonstrate that galectin-8, a β-galactoside-binding lectin, is upregulated in the epidermis of human psoriatic skin lesions, as well as a mouse model of psoriasis induced by intradermal IL-23 injections, and in IL-17A-treated keratinocytes.
Mon Mar 01 00:00:00 EST 2021
IL-9 Abrogates the Metastatic Potential of Breast Cancer by Controlling Extracellular Matrix Remodeling and Cellular Contractility.
Journal of immunology (Baltimore, Md. : 1950)
Das S,Surve V,Marathe S,Wad S,Karulkar A,Srinivasan S,Dwivedi A,Barthel SR,Purwar R
Tue Jun 01 00:00:00 EDT 2021
Synthetic liver fibrotic niche extracts achieve in vitro hepatoblasts phenotype enhancement and expansion.
iScience
Zhang Y,Guo A,Lyu C,Bi R,Wu Z,Li W,Zhao P,Niu Y,Na J,Xi JJ,Du Y
Fri Nov 19 00:00:00 EST 2021
MiR-193b-3p-ERBB4 axis regulates psoriasis pathogenesis via modulating cellular proliferation and inflammatory-mediator production of keratinocytes.
Cell death & disease
Huang C,Zhong W,Ren X,Huang X,Li Z,Chen C,Jiang B,Chen Z,Jian X,Yang L,Liu X,Huang H,Shen C,Chen X,Dou X,Yu B
Tue Oct 19 00:00:00 EDT 2021
RPL22 Overexpression Promotes Psoriasis-Like Lesion by Inducing Keratinocytes Abnormal Biological Behavior.
Frontiers in immunology
Zeng J,Zhang Y,Zhang H,Zhang Y,Gao L,Tong X,Xie Y,Hu Q,Chen C,Ding S,Lu J
200-17 was used in Sample Preparation to study the specific mechanism leading to the abnormal biological behavior of keratinocytes and suggest that RPL22 regulates keratinocytes abnormal biological behavior and contributes to the development of psoriatic phenotypes.
Mon Dec 13 00:00:00 EST 2021
Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration.
Frontiers in pharmacology
Skovdahl HK,Gopalakrishnan S,Svendsen TD,Granlund AVB,Bakke I,Ginbot ZG,Thorsvik S,Flatberg A,Sporsheim B,Ostrop J,Mollnes TE,Sandvik AK,Bruland T
200-17 was used in In vitro experiments to indicate that an oxygen concentration similar to the in vivo epithelial cell environment is of essence in experimental pharmacology.
Tue Jun 01 00:00:00 EDT 2021
Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer.
Nature communications
Wang W,Tang YA,Xiao Q,Lee WC,Cheng B,Niu Z,Oguz G,Feng M,Lee PL,Li B,Yang ZH,Chen YF,Lan P,Wu XJ,Yu Q
Wed Jul 21 00:00:00 EDT 2021
Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer.
Nature communications
Wang W,Tang YA,Xiao Q,Lee WC,Cheng B,Niu Z,Oguz G,Feng M,Lee PL,Li B,Yang ZH,Chen YF,Lan P,Wu XJ,Yu Q
Wed Jul 21 00:00:00 EDT 2021
ATF6 aggravates angiogenesis-osteogenesis coupling during ankylosing spondylitis by mediating FGF2 expression in chondrocytes.
iScience
Ma M,Li H,Wang P,Yang W,Mi R,Zhuang J,Jiang Y,Lu Y,Shen X,Wu Y,Shen H
200-17 was used in Cell Culture to find that activating transcription factor 6 and fibroblast growth factor 2 levels were higher in SKG mice and in cartilage of pateints with ankylosing spondylitis-1.
Fri Jul 23 00:00:00 EDT 2021
The Global Phosphorylation Landscape of SARS-CoV-2 Infection.
Cell
Bouhaddou M,Memon D,Meyer B,White KM,Rezelj VV,Correa Marrero M,Polacco BJ,Melnyk JE,Ulferts S,Kaake RM,Batra J,Richards AL,Stevenson E,Gordon DE,Rojc A,Obernier K,Fabius JM,Soucheray M,Miorin L,Moreno E,Koh C,Tran QD,Hardy A,Robinot R,Vallet T,Nilsson-Payant BE,Hernandez-Armenta C,Dunham A,Weigang S,Knerr J,Modak M,Quintero D,Zhou Y,Dugourd A,Valdeolivas A,Patil T,Li Q,Hüttenhain R,Cakir M,Muralidharan M,Kim M,Jang G,Tutuncuoglu B,Hiatt J,Guo JZ,Xu J,Bouhaddou S,Mathy CJP,Gaulton A,Manners EJ,Félix E,Shi Y,Goff M,Lim JK,McBride T,O'Neal MC,Cai Y,Chang JCJ,Broadhurst DJ,Klippsten S,De Wit E,Leach AR,Kortemme T,Shoichet B,Ott M,Saez-Rodriguez J,tenOever BR,Mullins RD,Fischer ER,Kochs G,Grosse R,García-Sastre A,Vignuzzi M,Johnson JR,Shokat KM,Swaney DL,Beltrao P,Krogan NJ
Thu Aug 06 00:00:00 EDT 2020
The Global Phosphorylation Landscape of SARS-CoV-2 Infection.
Cell
Bouhaddou M,Memon D,Meyer B,White KM,Rezelj VV,Correa Marrero M,Polacco BJ,Melnyk JE,Ulferts S,Kaake RM,Batra J,Richards AL,Stevenson E,Gordon DE,Rojc A,Obernier K,Fabius JM,Soucheray M,Miorin L,Moreno E,Koh C,Tran QD,Hardy A,Robinot R,Vallet T,Nilsson-Payant BE,Hernandez-Armenta C,Dunham A,Weigang S,Knerr J,Modak M,Quintero D,Zhou Y,Dugourd A,Valdeolivas A,Patil T,Li Q,Hüttenhain R,Cakir M,Muralidharan M,Kim M,Jang G,Tutuncuoglu B,Hiatt J,Guo JZ,Xu J,Bouhaddou S,Mathy CJP,Gaulton A,Manners EJ,Félix E,Shi Y,Goff M,Lim JK,McBride T,O'Neal MC,Cai Y,Chang JCJ,Broadhurst DJ,Klippsten S,De Wit E,Leach AR,Kortemme T,Shoichet B,Ott M,Saez-Rodriguez J,tenOever BR,Mullins RD,Fischer ER,Kochs G,Grosse R,García-Sastre A,Vignuzzi M,Johnson JR,Shokat KM,Swaney DL,Beltrao P,Krogan NJ
Thu Aug 06 00:00:00 EDT 2020
Kidney injury enhances renal G-CSF expression and modulates granulopoiesis and human neutrophil CD177 in vivo.
Clinical and experimental immunology
Volkmann J,Schmitz J,Nordlohne J,Dong L,Helmke A,Sen P,Immenschuh S,Bernhardt WM,Gwinner W,Bräsen JH,Schmitt R,Haller H,von Vietinghoff S
Wed Jan 01 00:00:00 EST 2020
EZH2-dependent epigenetic modulation of histone H3 lysine-27 contributes to psoriasis by promoting keratinocyte proliferation.
Cell death & disease
Zhang T,Yang L,Ke Y,Lei J,Shen S,Shao S,Zhang C,Zhu Z,Dang E,Wang G
Sat Oct 03 00:00:00 EDT 2020
Topical application of endothelin receptor a antagonist attenuates imiquimod-induced psoriasiform skin inflammation.
Scientific reports
Nakahara T,Kido-Nakahara M,Ulzii D,Miake S,Fujishima K,Sakai S,Chiba T,Tsuji G,Furue M
Thu Jun 11 00:00:00 EDT 2020
Progranulin sustains STAT3 hyper-activation and oncogenic function in colorectal cancer cells.
Molecular oncology
Laudisi F,Cherubini F,Di Grazia A,Dinallo V,Di Fusco D,Franzè E,Ortenzi A,Salvatori I,Scaricamazza S,Monteleone I,Sakamoto N,Monteleone G,Stolfi C
Tue Oct 01 00:00:00 EDT 2019
MLN4924 protects against interleukin-17A-induced pulmonary inflammation by disrupting ACT1-mediated signaling.
American journal of physiology. Lung cellular and molecular physiology
Hao R,Song Y,Li R,Wu Y,Yang X,Li X,Qian F,Ye RD,Sun L
200-17 was used in In vivo experiments to uncover a previously uncharacterized inhibitory effect of MLN4924 on the IL-17A-mediated inflammatory response; this phenomenon may facilitate the development of MLN4924 into an effective small-molecule drug for the treatment of pulmonary inflammatory diseases.
Sat Jun 01 00:00:00 EDT 2019
Interleukin-17A affects extracellular vesicles release and cargo in human keratinocytes.
Experimental dermatology
Mangino G,Iuliano M,Carlomagno S,Bernardini N,Rosa P,Chiantore MV,Skroza N,Calogero A,Potenza C,Romeo G
Sun Sep 01 00:00:00 EDT 2019
NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester.
Cell biochemistry and function
Zhang Y,Zhang Y,Li C,Fu S,Yang C,Song Y,Liu M,Wang Z,Liang P,Zhang J
200-17 was used in Cell Culture to indicate that RPL may be associated with NOD1 aberrant expression in DSCs, which plays a significant role in maintaining pregnancy via infection control and regulation of immune responses that might affect the pregnancy outcome.
Tue Oct 01 00:00:00 EDT 2019
(5R)-5-Hydroxytriptolide (LLDT-8) induces substantial epigenetic mediated immune response network changes in fibroblast-like synoviocytes from rheumatoid arthritis patients.
Scientific reports
Guo S,Liu J,Jiang T,Lee D,Wang R,Zhou X,Jin Y,Shen Y,Wang Y,Bai F,Ding Q,Wang G,Zhang J,Zhou X,Schrodi SJ,He D
Thu Aug 01 00:00:00 EDT 2019
Effects of interleukin-17A in nucleus pulposus cells and its small-molecule inhibitors for intervertebral disc disease.
Journal of cellular and molecular medicine
Suyama K,Sakai D,Hirayama N,Nakamura Y,Matsushita E,Terayama H,Qu N,Tanaka O,Sakabe K,Watanabe M
Thu Nov 01 00:00:00 EDT 2018
MicroRNA-17-92 cluster promotes the proliferation and the chemokine production of keratinocytes: implication for the pathogenesis of psoriasis.
Cell death & disease
Zhang W,Yi X,An Y,Guo S,Li S,Song P,Chang Y,Zhang S,Gao T,Wang G,Li C
Tue May 01 00:00:00 EDT 2018
C10orf99 contributes to the development of psoriasis by promoting the proliferation of keratinocytes.
Scientific reports
Chen C,Wu N,Duan Q,Yang H,Wang X,Yang P,Zhang M,Liu J,Liu Z,Shao Y,Zheng Y
Tue Jun 05 00:00:00 EDT 2018
The Therapeutic Potential and Molecular Mechanism of Isoflavone Extract against Psoriasis.
Scientific reports
Li HJ,Wu NL,Lee GA,Hung CF
Fri Apr 20 00:00:00 EDT 2018
IL-4/IL-13 Heteroreceptor Influences Th17 Cell Conversion and Sensitivity to Regulatory T Cell Suppression To Restrain Experimental Allergic Encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Barik S,Ellis JS,Cascio JA,Miller MM,Ukah TK,Cattin-Roy AN,Zaghouani H
Sun Oct 01 00:00:00 EDT 2017
GATA3 regulates FLG and FLG2 expression in human primary keratinocytes.
Scientific reports
Zeitvogel J,Jokmin N,Rieker S,Klug I,Brandenberger C,Werfel T
Tue Sep 19 00:00:00 EDT 2017
The psoriasis-associated IL-17A induces and cooperates with IL-36 cytokines to control keratinocyte differentiation and function.
Scientific reports
Pfaff CM,Marquardt Y,Fietkau K,Baron JM,Lüscher B
Wed Nov 15 00:00:00 EST 2017
The psoriasis-associated IL-17A induces and cooperates with IL-36 cytokines to control keratinocyte differentiation and function.
Scientific reports
Pfaff CM,Marquardt Y,Fietkau K,Baron JM,Lüscher B
Wed Nov 15 00:00:00 EST 2017
Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis.
The Journal of clinical investigation
Egan CE,Sodhi CP,Good M,Lin J,Jia H,Yamaguchi Y,Lu P,Ma C,Branca MF,Weyandt S,Fulton WB,Niño DF,Prindle T,Ozolek JA,Hackam DJ
Mon Feb 01 00:00:00 EST 2016
Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.
The Journal of clinical investigation
Cantaert T,Schickel JN,Bannock JM,Ng YS,Massad C,Delmotte FR,Yamakawa N,Glauzy S,Chamberlain N,Kinnunen T,Menard L,Lavoie A,Walter JE,Notarangelo LD,Bruneau J,Al-Herz W,Kilic SS,Ochs HD,Cunningham-Rundles C,van der Burg M,Kuijpers TW,Kracker S,Kaneko H,Sekinaka Y,Nonoyama S,Durandy A,Meffre E
Tue Nov 01 00:00:00 EDT 2016
IL-17 Promotes Angiogenic Factors IL-6, IL-8, and Vegf Production via Stat1 in Lung Adenocarcinoma.
Scientific reports
Huang Q,Duan L,Qian X,Fan J,Lv Z,Zhang X,Han J,Wu F,Guo M,Hu G,Du J,Chen C,Jin Y
Mon Nov 07 00:00:00 EST 2016
Modulation of IL-6 induced RANKL expression in arthritic synovium by a transcription factor SOX5.
Scientific reports
Feng X,Shi Y,Xu L,Peng Q,Wang F,Wang X,Sun W,Lu Y,Tsao BP,Zhang M,Tan W
200-17 was used in Tissue/Organ culture to study the regulation of SOX5 levels in relation to receptor activator of nuclear factor κB ligand (RANKL) expression in rheumatoid arthritis (RA) in synovial fibroblasts (SF) and the development of bone erosion in the collagen-induced arthritis (CIA) mouse.
Tue Aug 23 00:00:00 EDT 2016
MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation.
Immunity
Garg AV,Amatya N,Chen K,Cruz JA,Grover P,Whibley N,Conti HR,Hernandez Mir G,Sirakova T,Childs EC,Smithgall TE,Biswas PS,Kolls JK,McGeachy MJ,Kolattukudy PE,Gaffen SL
Tue Sep 15 00:00:00 EDT 2015
The parasitic worm product ES-62 targets myeloid differentiation factor 88-dependent effector mechanisms to suppress antinuclear antibody production and proteinuria in MRL/lpr mice.
Arthritis & rheumatology (Hoboken, N.J.)
Rodgers DT,McGrath MA,Pineda MA,Al-Riyami L,Rzepecka J,Lumb F,Harnett W,Harnett MM
Wed Apr 01 00:00:00 EDT 2015
Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth.
Oncogene
De Simone V,Franzè E,Ronchetti G,Colantoni A,Fantini MC,Di Fusco D,Sica GS,Sileri P,MacDonald TT,Pallone F,Monteleone G,Stolfi C
Wed Jul 01 00:00:00 EDT 2015
Human monocyte-derived dendritic cells turn into foamy dendritic cells with IL-17A.
Journal of lipid research
Salvatore G,Bernoud-Hubac N,Bissay N,Debard C,Daira P,Meugnier E,Proamer F,Hanau D,Vidal H,Aricò M,Delprat C,Mahtouk K
Mon Jun 01 00:00:00 EDT 2015
Human white and brite adipogenesis is supported by MSCA1 and is impaired by immune cells.
Stem cells (Dayton, Ohio)
Estève D,Boulet N,Volat F,Zakaroff-Girard A,Ledoux S,Coupaye M,Decaunes P,Belles C,Gaits-Iacovoni F,Iacovoni JS,Rémaury A,Castel B,Ferrara P,Heymes C,Lafontan M,Bouloumié A,Galitzky J
Wed Apr 01 00:00:00 EDT 2015
Interleukin-17A-Induced Human Mesenchymal Stem Cells Are Superior Modulators of Immunological Function.
Stem cells (Dayton, Ohio)
Sivanathan KN,Rojas-Canales DM,Hope CM,Krishnan R,Carroll RP,Gronthos S,Grey ST,Coates PT
Tue Sep 01 00:00:00 EDT 2015
Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice.
Scientific reports
Liu J,Zhou F,Chen Q,Kang A,Lu M,Liu W,Zang X,Wang G,Zhang J
Tue Sep 01 00:00:00 EDT 2015
IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection.
Nature communications
Adoro S,Cubillos-Ruiz JR,Chen X,Deruaz M,Vrbanac VD,Song M,Park S,Murooka TT,Dudek TE,Luster AD,Tager AM,Streeck H,Bowman B,Walker BD,Kwon DS,Lazarevic V,Glimcher LH
Thu Jun 25 00:00:00 EDT 2015
Cytokine-stimulated Phosphoflow of PBMC Using CyTOF Mass Cytometry.
Bio-protocol
Fernandez R,Maecker H
200-17 was used in Cell Culture to use phosphoprotein-specific antibodies with flow cytometry to study the level of phosphorylation of intracellular proteins in response to stimulation by cytokines, and use this process to gain insight to the status of the immune system.
Fri Jun 05 00:00:00 EDT 2015
Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression.
Immunity
Stephen TL,Rutkowski MR,Allegrezza MJ,Perales-Puchalt A,Tesone AJ,Svoronos N,Nguyen JM,Sarmin F,Borowsky ME,Tchou J,Conejo-Garcia JR
Thu Sep 18 00:00:00 EDT 2014
IL-17 protects T cells from apoptosis and contributes to development of ALPS-like phenotypes.
Blood
Boggio E,Clemente N,Mondino A,Cappellano G,Orilieri E,Gigliotti CL,Toth E,Ramenghi U,Dianzani U,Chiocchetti A
Thu Feb 20 00:00:00 EST 2014
Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis.
Proceedings of the National Academy of Sciences of the United States of America
Gobbetti T,Coldewey SM,Chen J,McArthur S,le Faouder P,Cenac N,Flower RJ,Thiemermann C,Perretti M
Tue Dec 30 00:00:00 EST 2014
Th17 cells and interleukin-17 increase with poor prognosis in patients with acute myeloid leukemia.
Cancer science
Han Y,Ye A,Bi L,Wu J,Yu K,Zhang S
Fri Aug 01 00:00:00 EDT 2014
DNAX-activating protein 10 (DAP10) membrane adaptor associates with receptor for advanced glycation end products (RAGE) and modulates the RAGE-triggered signaling pathway in human keratinocytes.
The Journal of biological chemistry
Sakaguchi M,Murata H,Aoyama Y,Hibino T,Putranto EW,Ruma IM,Inoue Y,Sakaguchi Y,Yamamoto K,Kinoshita R,Futami J,Kataoka K,Iwatsuki K,Huh NH
Fri Aug 22 00:00:00 EDT 2014
Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy.
PloS one
Zhang YY,Chen H,Sun C,Wang HZ,Liu ML,Li YY,Nie XL,Du MR,Li DJ,Zhang JP
200-17 was used in Cell Culture to investigate the effects of NOD2 expression on the maternal-fetal relationship in normal decidual stromal cells.
Thu Oct 22 00:00:00 EDT 2015
Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy.
PloS one
Zhang YY,Chen H,Sun C,Wang HZ,Liu ML,Li YY,Nie XL,Du MR,Li DJ,Zhang JP
200-17 was used in Cell Culture to investigate the effects of NOD2 expression on the maternal-fetal relationship in normal decidual stromal cells.
Thu Oct 22 00:00:00 EDT 2015
IL-17A is produced by breast cancer TILs and promotes chemoresistance and proliferation through ERK1/2.
Scientific reports
Cochaud S,Giustiniani J,Thomas C,Laprevotte E,Garbar C,Savoye AM,Curé H,Mascaux C,Alberici G,Bonnefoy N,Eliaou JF,Bensussan A,Bastid J
Mon Dec 09 00:00:00 EST 2013
Chemoresistance of human monocyte-derived dendritic cells is regulated by IL-17A.
PloS one
Olsson Åkefeldt S,Maisse C,Belot A,Mazzorana M,Salvatore G,Bissay N,Jurdic P,Aricò M,Rabourdin-Combe C,Henter JI,Delprat C
Tue Aug 13 00:00:00 EDT 2013
Induction of endothelial nitric oxide synthase expression by IL-17 in human vascular endothelial cells: implications for vascular remodeling in transplant vasculopathy.
Journal of immunology (Baltimore, Md. : 1950)
Liu AC,Lee M,McManus BM,Choy JC
Wed Feb 01 00:00:00 EST 2012
IL-17 receptor adaptor protein Act1/CIKS plays an evolutionarily conserved role in antiviral signaling.
Journal of immunology (Baltimore, Md. : 1950)
Ryzhakov G,Blazek K,Lai CC,Udalova IA
Thu Nov 15 00:00:00 EST 2012
IL-17A facilitates platelet function through the ERK2 signaling pathway in patients with acute coronary syndrome.
PloS one
Zhang S,Yuan J,Yu M,Fan H,Guo ZQ,Yang R,Guo HP,Liao YH,Wang M
Thu Jan 10 00:00:00 EST 2013
A novel pro-lymphangiogenic function for Th17/IL-17.
Blood
Chauhan SK,Jin Y,Goyal S,Lee HS,Fuchsluger TA,Lee HK,Dana R
Thu Oct 27 00:00:00 EDT 2011
Dual role of interleukin-17 in pannus growth and osteoclastogenesis in rheumatoid arthritis.
Arthritis research & therapy
Ito H,Yamada H,Shibata TN,Mitomi H,Nomoto S,Ozaki S
Fri Feb 04 00:00:00 EST 2011
IL-17 boosts proinflammatory outcome of antiviral response in human cells.
Journal of immunology (Baltimore, Md. : 1950)
Ryzhakov G,Lai CC,Blazek K,To KW,Hussell T,Udalova I
Tue Nov 15 00:00:00 EST 2011
CXCR5 expressing human central memory CD4 T cells and their relevance for humoral immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Chevalier N,Jarrossay D,Ho E,Avery DT,Ma CS,Yu D,Sallusto F,Tangye SG,Mackay CR
Sun May 15 00:00:00 EDT 2011
Murine insulin growth factor-like (IGFL) and human IGFL1 proteins are induced in inflammatory skin conditions and bind to a novel tumor necrosis factor receptor family member, IGFLR1.
The Journal of biological chemistry
Lobito AA,Ramani SR,Tom I,Bazan JF,Luis E,Fairbrother WJ,Ouyang W,Gonzalez LC
Fri May 27 00:00:00 EDT 2011
Flagellin delivery by Pseudomonas aeruginosa rhamnolipids induces the antimicrobial protein psoriasin in human skin.
PloS one
Meyer-Hoffert U,Zimmermann A,Czapp M,Bartels J,Koblyakova Y,Gläser R,Schröder JM,Gerstel U
Tue Jan 25 00:00:00 EST 2011
Evidence for a cross-talk between human neutrophils and Th17 cells.
Blood
Pelletier M,Maggi L,Micheletti A,Lazzeri E,Tamassia N,Costantini C,Cosmi L,Lunardi C,Annunziato F,Romagnani S,Cassatella MA
Thu Jan 14 00:00:00 EST 2010
IL-17RC is required for immune signaling via an extended SEF/IL-17R signaling domain in the cytoplasmic tail.
Journal of immunology (Baltimore, Md. : 1950)
Ho AW,Shen F,Conti HR,Patel N,Childs EE,Peterson AC,Hernández-Santos N,Kolls JK,Kane LP,Ouyang W,Gaffen SL
Thu Jul 15 00:00:00 EDT 2010
Intensive chemotherapy for acute myeloid leukemia differentially affects circulating TC1, TH1, TH17 and TREG cells.
BMC immunology
Ersvaer E,Liseth K,Skavland J,Gjertsen BT,Bruserud Ø
Fri Jul 09 00:00:00 EDT 2010
Delineation of the innate and adaptive T-cell immune outcome in the human host in response to Campylobacter jejuni infection.
PloS one
Edwards LA,Nistala K,Mills DC,Stephenson HN,Zilbauer M,Wren BW,Dorrell N,Lindley KJ,Wedderburn LR,Bajaj-Elliott M
Tue Nov 09 00:00:00 EST 2010
Increased hyaluronan production and decreased E-cadherin expression by cytokine-stimulated keratinocytes lead to spongiosis formation.
The Journal of investigative dermatology
Ohtani T,Memezawa A,Okuyama R,Sayo T,Sugiyama Y,Inoue S,Aiba S
Mon Jun 01 00:00:00 EDT 2009
Phenotypical characterization of human Th17 cells unambiguously identified by surface IL-17A expression.
Journal of immunology (Baltimore, Md. : 1950)
Brucklacher-Waldert V,Steinbach K,Lioznov M,Kolster M,Hölscher C,Tolosa E
Sun Nov 01 00:00:00 EDT 2009
Microdialysis of cytokines: methodological considerations, scanning electron microscopy, and determination of relative recovery.
Journal of neurotrauma
Helmy A,Carpenter KL,Skepper JN,Kirkpatrick PJ,Pickard JD,Hutchinson PJ
Wed Apr 01 00:00:00 EDT 2009
Tumor-like stem cells derived from human keloid are governed by the inflammatory niche driven by IL-17/IL-6 axis.
PloS one
Zhang Q,Yamaza T,Kelly AP,Shi S,Wang S,Brown J,Wang L,French SW,Shi S,Le AD
Wed Nov 11 00:00:00 EST 2009
Differential regulation of the IL-17 receptor by gammac cytokines: inhibitory signaling by the phosphatidylinositol 3-kinase pathway.
The Journal of biological chemistry
Lindemann MJ,Hu Z,Benczik M,Liu KD,Gaffen SL
Fri May 16 00:00:00 EDT 2008
Cutting edge: identification of a pre-ligand assembly domain (PLAD) and ligand binding site in the IL-17 receptor.
Journal of immunology (Baltimore, Md. : 1950)
Kramer JM,Hanel W,Shen F,Isik N,Malone JP,Maitra A,Sigurdson W,Swart D,Tocker J,Jin T,Gaffen SL
Thu Nov 15 00:00:00 EST 2007
Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression.
Cancer research
Hemminki A,Kanerva A,Liu B,Wang M,Alvarez RD,Siegal GP,Curiel DT
Sat Feb 15 00:00:00 EST 2003
IL-17 expression in human herpetic stromal keratitis: modulatory effects on chemokine production by corneal fibroblasts.
Journal of immunology (Baltimore, Md. : 1950)
Maertzdorf J,Osterhaus AD,Verjans GM
Fri Nov 15 00:00:00 EST 2002