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Product Details
200-28-100UG
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Published species
Not Applicable
Expression System
E. coli
Amino acid sequence
MQPRSPKSKR KGQGRPGPLA PGPHQVPLDL VSRMKPYARM EEYERNIEEM VAQLRNSSEL AQRKCEVNLQ LWMSNKRSLS PWGYSINHDP SRIPVDLPEA RCLCLGCVNP FTMQEDRSMV SVPVFSQVPV RRRLCPPPPR TGPCRQRAVM ETIAVGCTCI F
Molecular weight
36.6 kDa
Class
Recombinant
Type
Protein
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10ng-100ng. Note: Results may vary with PBMC donors.
Conjugate
Form
Lyophilized
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
200-28-1MG will be provided as 2 x 500 µg (200-28-500UG).
Recombinant Human IL-17B is a 36.6 kDa non-disulfide-linked homodimer of two 161 amino acid polypeptide chains.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cytokine Zcyto7; cytokine-like protein ZCYTO7; IL-17B; IL-20; interleukin 20; interleukin-17 beta; Interleukin-17B; Interleukin-20; Interleukin20; neuronal interleukin-17 related factor; Neuronal interleukin-17-related factor
Gene Aliases: IL-17B; IL-20; IL17B; IL20; NIRF; UNQ516/PRO1031; ZCYTO7
UniProt ID: (Human) Q9UHF5
Entrez Gene ID: (Human) 27190
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