Product References
Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis.
JID innovations : skin science from molecules to population health
Niehues H,Rikken G,van Vlijmen-Willems IMJJ,Rodijk-Olthuis D,van Erp PEJ,Zeeuwen PLJM,Schalkwijk J,van den Bogaard EH
200-22 was used in In vitro experiments to investigate the mitogens involved in keratinocyte proliferation and stratification.
Sat Jan 01 00:00:00 EST 2022
MiR-193b-3p-ERBB4 axis regulates psoriasis pathogenesis via modulating cellular proliferation and inflammatory-mediator production of keratinocytes.
Cell death & disease
Huang C,Zhong W,Ren X,Huang X,Li Z,Chen C,Jiang B,Chen Z,Jian X,Yang L,Liu X,Huang H,Shen C,Chen X,Dou X,Yu B
Tue Oct 19 00:00:00 EDT 2021
RPL22 Overexpression Promotes Psoriasis-Like Lesion by Inducing Keratinocytes Abnormal Biological Behavior.
Frontiers in immunology
Zeng J,Zhang Y,Zhang H,Zhang Y,Gao L,Tong X,Xie Y,Hu Q,Chen C,Ding S,Lu J
200-22 was used in Sample Preparation to study the specific mechanism leading to the abnormal biological behavior of keratinocytes and suggest that RPL22 regulates keratinocytes abnormal biological behavior and contributes to the development of psoriatic phenotypes.
Mon Dec 13 00:00:00 EST 2021
The Global Phosphorylation Landscape of SARS-CoV-2 Infection.
Cell
Bouhaddou M,Memon D,Meyer B,White KM,Rezelj VV,Correa Marrero M,Polacco BJ,Melnyk JE,Ulferts S,Kaake RM,Batra J,Richards AL,Stevenson E,Gordon DE,Rojc A,Obernier K,Fabius JM,Soucheray M,Miorin L,Moreno E,Koh C,Tran QD,Hardy A,Robinot R,Vallet T,Nilsson-Payant BE,Hernandez-Armenta C,Dunham A,Weigang S,Knerr J,Modak M,Quintero D,Zhou Y,Dugourd A,Valdeolivas A,Patil T,Li Q,Hüttenhain R,Cakir M,Muralidharan M,Kim M,Jang G,Tutuncuoglu B,Hiatt J,Guo JZ,Xu J,Bouhaddou S,Mathy CJP,Gaulton A,Manners EJ,Félix E,Shi Y,Goff M,Lim JK,McBride T,O'Neal MC,Cai Y,Chang JCJ,Broadhurst DJ,Klippsten S,De Wit E,Leach AR,Kortemme T,Shoichet B,Ott M,Saez-Rodriguez J,tenOever BR,Mullins RD,Fischer ER,Kochs G,Grosse R,García-Sastre A,Vignuzzi M,Johnson JR,Shokat KM,Swaney DL,Beltrao P,Krogan NJ
200-22 was used in Enzyme-linked immunosorbent assay to present a quantitative mass spectrometry-based phosphoproteomics survey of SARS-CoV-2 infection in Vero E6 cells, revealing dramatic rewiring of phosphorylation on host and viral proteins.
Thu Aug 06 00:00:00 EDT 2020
The Global Phosphorylation Landscape of SARS-CoV-2 Infection.
Cell
Bouhaddou M,Memon D,Meyer B,White KM,Rezelj VV,Correa Marrero M,Polacco BJ,Melnyk JE,Ulferts S,Kaake RM,Batra J,Richards AL,Stevenson E,Gordon DE,Rojc A,Obernier K,Fabius JM,Soucheray M,Miorin L,Moreno E,Koh C,Tran QD,Hardy A,Robinot R,Vallet T,Nilsson-Payant BE,Hernandez-Armenta C,Dunham A,Weigang S,Knerr J,Modak M,Quintero D,Zhou Y,Dugourd A,Valdeolivas A,Patil T,Li Q,Hüttenhain R,Cakir M,Muralidharan M,Kim M,Jang G,Tutuncuoglu B,Hiatt J,Guo JZ,Xu J,Bouhaddou S,Mathy CJP,Gaulton A,Manners EJ,Félix E,Shi Y,Goff M,Lim JK,McBride T,O'Neal MC,Cai Y,Chang JCJ,Broadhurst DJ,Klippsten S,De Wit E,Leach AR,Kortemme T,Shoichet B,Ott M,Saez-Rodriguez J,tenOever BR,Mullins RD,Fischer ER,Kochs G,Grosse R,García-Sastre A,Vignuzzi M,Johnson JR,Shokat KM,Swaney DL,Beltrao P,Krogan NJ
200-22 was used in Enzyme-linked immunosorbent assay to present a quantitative mass spectrometry-based phosphoproteomics survey of SARS-CoV-2 infection in Vero E6 cells, revealing dramatic rewiring of phosphorylation on host and viral proteins.
Thu Aug 06 00:00:00 EDT 2020
Challenges and Pitfalls in the Engineering of Human Interleukin 22 (hIL-22) Secreting Lactobacillus reuteri.
Frontiers in bioengineering and biotechnology
Ortiz-Velez L,Goodwin A,Schaefer L,Britton RA
200-22 was used in Western Blotting to investigate development of engineered microbes to treat inflammatory bowel disease and intestinal graft disease.
Mon Sep 28 00:00:00 EDT 2020
EZH2-dependent epigenetic modulation of histone H3 lysine-27 contributes to psoriasis by promoting keratinocyte proliferation.
Cell death & disease
Zhang T,Yang L,Ke Y,Lei J,Shen S,Shao S,Zhang C,Zhu Z,Dang E,Wang G
Sat Oct 03 00:00:00 EDT 2020
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis.
Cell
Smillie CS,Biton M,Ordovas-Montanes J,Sullivan KM,Burgin G,Graham DB,Herbst RH,Rogel N,Slyper M,Waldman J,Sud M,Andrews E,Velonias G,Haber AL,Jagadeesh K,Vickovic S,Yao J,Stevens C,Dionne D,Nguyen LT,Villani AC,Hofree M,Creasey EA,Huang H,Rozenblatt-Rosen O,Garber JJ,Khalili H,Desch AN,Daly MJ,Ananthakrishnan AN,Shalek AK,Xavier RJ,Regev A
Thu Jul 25 00:00:00 EDT 2019
STAT3 and STAT5 Signaling Thresholds Determine Distinct Regulation for Innate Receptor-Induced Inflammatory Cytokines, and STAT3/STAT5 Disease Variants Modulate These Outcomes.
Journal of immunology (Baltimore, Md. : 1950)
Hedl M,Sun R,Huang C,Abraham C
Sun Dec 15 00:00:00 EST 2019
IL-22 and IL-22-Binding Protein Are Associated With Development of and Mortality From Acute-on-Chronic Liver Failure.
Hepatology communications
Schwarzkopf K,Rüschenbaum S,Barat S,Cai C,Mücke MM,Fitting D,Weigert A,Brüne B,Zeuzem S,Welsch C,Lange CM
Fri Mar 01 00:00:00 EST 2019
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING.
The Journal of experimental medicine
Aden K,Tran F,Ito G,Sheibani-Tezerji R,Lipinski S,Kuiper JW,Tschurtschenthaler M,Saveljeva S,Bhattacharyya J,Häsler R,Bartsch K,Luzius A,Jentzsch M,Falk-Paulsen M,Stengel ST,Welz L,Schwarzer R,Rabe B,Barchet W,Krautwald S,Hartmann G,Pasparakis M,Blumberg RS,Schreiber S,Kaser A,Rosenstiel P
Mon Nov 05 00:00:00 EST 2018
MicroRNA-17-92 cluster promotes the proliferation and the chemokine production of keratinocytes: implication for the pathogenesis of psoriasis.
Cell death & disease
Zhang W,Yi X,An Y,Guo S,Li S,Song P,Chang Y,Zhang S,Gao T,Wang G,Li C
Tue May 01 00:00:00 EDT 2018
Interleukin-2 induces the in vitro maturation of human pluripotent stem cell-derived intestinal organoids.
Nature communications
Jung KB,Lee H,Son YS,Lee MO,Kim YD,Oh SJ,Kwon O,Cho S,Cho HS,Kim DS,Oh JH,Zilbauer M,Min JK,Jung CR,Kim J,Son MY
Thu Aug 02 00:00:00 EDT 2018
C10orf99 contributes to the development of psoriasis by promoting the proliferation of keratinocytes.
Scientific reports
Chen C,Wu N,Duan Q,Yang H,Wang X,Yang P,Zhang M,Liu J,Liu Z,Shao Y,Zheng Y
Tue Jun 05 00:00:00 EDT 2018
The Therapeutic Potential and Molecular Mechanism of Isoflavone Extract against Psoriasis.
Scientific reports
Li HJ,Wu NL,Lee GA,Hung CF
Fri Apr 20 00:00:00 EDT 2018
A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis.
The Journal of experimental medicine
Schwerd T,Twigg SRF,Aschenbrenner D,Manrique S,Miller KA,Taylor IB,Capitani M,McGowan SJ,Sweeney E,Weber A,Chen L,Bowness P,Riordan A,Cant A,Freeman AF,Milner JD,Holland SM,Frede N,Müller M,Schmidt-Arras D,Grimbacher B,Wall SA,Jones EY,Wilkie AOM,Uhlig HH
Mon Sep 04 00:00:00 EDT 2017
GATA3 regulates FLG and FLG2 expression in human primary keratinocytes.
Scientific reports
Zeitvogel J,Jokmin N,Rieker S,Klug I,Brandenberger C,Werfel T
Tue Sep 19 00:00:00 EDT 2017
Interleukin-22 ameliorated renal injury and fibrosis in diabetic nephropathy through inhibition of NLRP3 inflammasome activation.
Cell death & disease
Wang S,Li Y,Fan J,Zhang X,Luan J,Bian Q,Ding T,Wang Y,Wang Z,Song P,Cui D,Mei X,Ju D
Thu Jul 20 00:00:00 EDT 2017
PGE2 is a direct and robust mediator of anion/fluid secretion by human intestinal epithelial cells.
Scientific reports
Fujii S,Suzuki K,Kawamoto A,Ishibashi F,Nakata T,Murano T,Ito G,Shimizu H,Mizutani T,Oshima S,Tsuchiya K,Nakamura T,Araki A,Ohtsuka K,Okamoto R,Watanabe M
Wed Nov 09 00:00:00 EST 2016
Inhibition of TYK2 and JAK1 ameliorates imiquimod-induced psoriasis-like dermatitis by inhibiting IL-22 and the IL-23/IL-17 axis.
Journal of immunology (Baltimore, Md. : 1950)
Works MG,Yin F,Yin CC,Yiu Y,Shew K,Tran TT,Dunlap N,Lam J,Mitchell T,Reader J,Stein PL,D'Andrea A
Wed Oct 01 00:00:00 EDT 2014
Protein expression profiling of inflammatory mediators in human temporal lobe epilepsy reveals co-activation of multiple chemokines and cytokines.
Journal of neuroinflammation
Kan AA,de Jager W,de Wit M,Heijnen C,van Zuiden M,Ferrier C,van Rijen P,Gosselaar P,Hessel E,van Nieuwenhuizen O,de Graan PN
Thu Aug 30 00:00:00 EDT 2012
Murine insulin growth factor-like (IGFL) and human IGFL1 proteins are induced in inflammatory skin conditions and bind to a novel tumor necrosis factor receptor family member, IGFLR1.
The Journal of biological chemistry
Lobito AA,Ramani SR,Tom I,Bazan JF,Luis E,Fairbrother WJ,Ouyang W,Gonzalez LC
Fri May 27 00:00:00 EDT 2011
Flagellin delivery by Pseudomonas aeruginosa rhamnolipids induces the antimicrobial protein psoriasin in human skin.
PloS one
Meyer-Hoffert U,Zimmermann A,Czapp M,Bartels J,Koblyakova Y,Gläser R,Schröder JM,Gerstel U
Tue Jan 25 00:00:00 EST 2011
Delineation of the innate and adaptive T-cell immune outcome in the human host in response to Campylobacter jejuni infection.
PloS one
Edwards LA,Nistala K,Mills DC,Stephenson HN,Zilbauer M,Wren BW,Dorrell N,Lindley KJ,Wedderburn LR,Bajaj-Elliott M
Tue Nov 09 00:00:00 EST 2010
Multiparametric analysis of cytokine-driven human Th17 differentiation reveals a differential regulation of IL-17 and IL-22 production.
Blood
Volpe E,Touzot M,Servant N,Marloie-Provost MA,Hupé P,Barillot E,Soumelis V
Thu Oct 22 00:00:00 EDT 2009
Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease.
Immunity
Zenewicz LA,Yancopoulos GD,Valenzuela DM,Murphy AJ,Stevens S,Flavell RA
Fri Dec 19 00:00:00 EST 2008
Development and validation of human psoriatic skin equivalents.
The American journal of pathology
Tjabringa G,Bergers M,van Rens D,de Boer R,Lamme E,Schalkwijk J
Mon Sep 01 00:00:00 EDT 2008
Gene expression profiling in autoimmune noninfectious uveitis disease.
Journal of immunology (Baltimore, Md. : 1950)
Li Z,Liu B,Maminishkis A,Mahesh SP,Yeh S,Lew J,Lim WK,Sen HN,Clarke G,Buggage R,Miller SS,Nussenblatt RB
Wed Oct 01 00:00:00 EDT 2008
Inhibition of type I and type III interferons by a secreted glycoprotein from Yaba-like disease virus.
Proceedings of the National Academy of Sciences of the United States of America
Huang J,Smirnov SV,Lewis-Antes A,Balan M,Li W,Tang S,Silke GV,Pütz MM,Smith GL,Kotenko SV
Tue Jun 05 00:00:00 EDT 2007
The interleukin-22/STAT3 pathway potentiates expression of inducible nitric-oxide synthase in human colon carcinoma cells.
The Journal of biological chemistry
Ziesché E,Bachmann M,Kleinert H,Pfeilschifter J,Mühl H
Fri Jun 01 00:00:00 EDT 2007