Product References
Germline Neurofibromin 1 mutation enhances the anti-tumour immune response and decreases juvenile myelomonocytic leukaemia tumourigenicity.
British journal of haematology
Wang W,Li X,Qin X,Miao Y,Zhang Y,Li S,Yao R,Yang Y,Yu L,Zhu H,Song L,Mao S,Wang X,Chen J,Feng H,Li Y
200-04 was used in In vitro experiments to demonstrate that germline NF1 mutations alone cannot directly drive JMML development and suggest a potential cell immunotherapy for JMML patients.
Sat Jul 01 00:00:00 EDT 2023
Astrocytes express aberrant immunoglobulins as putative gatekeeper of astrocytes to neuronal progenitor conversion.
Cell death & disease
Capuz A,Osien S,Karnoub MA,Aboulouard S,Laurent E,Coyaud E,Raffo-Romero A,Duhamel M,Bonnefond A,Derhourhi M,Trerotola M,El Yazidi-Belkoura I,Devos D,Zilkova M,Kobeissy F,Vanden Abeele F,Fournier I,Cizkova D,Rodet F,Salzet M
200-04 was used in In vitro experiments to demonstrate that these chains are synthesized individually and associated to recognize specific targets.
Tue Apr 04 00:00:00 EDT 2023
Stereochemistry and functions of the new cysteinyl-resolvin, 4S,5R-RCTR1, in efferocytosis and erythrophagocytosis of human senescent erythrocytes.
American journal of hematology
Nshimiyimana R,Libreros S,Simard M,Chiang N,Rodriguez AR,Spur BW,Haeggström JZ,Serhan CN
200-04 was used in Cell Culture to establish the complete stereochemistry of 4S,5R-RCTR1 as 5R-glutathionyl-4S,17S-dihydroxy-6E,8E,10Z,13Z,15E,19Z-docosahexaenoic acid and give evidence of its novel bioactivities in human phagocyte responses.
Sat Jul 01 00:00:00 EDT 2023
Identification of cross-reactive CD8+ T cell receptors with high functional avidity to a SARS-CoV-2 immunodominant epitope and its natural mutant variants.
Genes & diseases
Hu C,Shen M,Han X,Chen Q,Li L,Chen S,Zhang J,Gao F,Wang W,Wang Y,Li T,Li S,Huang J,Wang J,Zhu J,Chen D,Wu Q,Tao K,Pang D,Jin A
Sat Jan 01 00:00:00 EST 2022
Staphylococcus aureus controls eicosanoid and specialized pro-resolving mediator production via lipoteichoic acid.
Immunology
Miek L,Jordan PM,Günther K,Pace S,Beyer T,Kowalak D,Hoerr V,Löffler B,Tuchscherr L,Serhan CN,Gerstmeier J,Werz O
Sun May 01 00:00:00 EDT 2022
Concurrent stimulation of monocytes with CSF1 and polarizing cytokines reveals phenotypic and functional differences with classical polarized macrophages.
Journal of leukocyte biology
An L,Michaeli J,Pallavi P,Breedijk A,Xu X,Dietrich N,Sigl M,Keese M,Nitschke K,Jarczyk J,Nuhn P,Krämer BK,Yard BA,Leipe J
Thu Sep 01 00:00:00 EDT 2022
Upregulation of CD3ζ and L-selectin in antigen-specific cytotoxic T lymphocytes by eliminating myeloid-derived suppressor cells with doxorubicin to improve killing efficacy of neuroblastoma cells in vitro.
Journal of clinical laboratory analysis
Xu W,Li S,Li M,Zhou H,Yang X
200-04 was used in Sample Preparation (FC/FACS) to investigate myeloid-derived suppressor cells in immunotherapy of cancer.
Sat Jan 01 00:00:00 EST 2022
Pyridoxamine ameliorates methylglyoxal-induced macrophage dysfunction to facilitate tissue repair in diabetic wounds.
International wound journal
Jiang M,Yakupu A,Guan H,Dong J,Liu Y,Song F,Tang J,Tian M,Niu Y,Lu S
Sat Jan 01 00:00:00 EST 2022
Sphingomyelin synthase 2 is a positive regulator of the CSF1R-STAT3 pathway in pancreatic cancer-associated macrophage.
Frontiers in pharmacology
He S,Gu X,Yang J,Xu F,Hu J,Wang W,Huang Y,Lou B,Ding T,Zhou L,Ye D,Yu K,Dong J
200-04 was used in Sample Preparation (Western Blotting) to study the role of sphingomyelin synthase 2 (SMS2) and the effect of the synthase 2 selective inhibitor YE2 in tumor-associated macrophage (TAMs) and the pancreatic tumor microenvironment.
Fri Nov 04 00:00:00 EDT 2022
Effects of macrophages on the proliferation and cardiac differentiation of human induced pluripotent stem cells.
Cell communication and signaling : CCS
Long C,Guo R,Han R,Li K,Wan Y,Xu J,Gong X,Zhao Y,Yao X,Liu J
200-04 was used in Cell Culture to study how macrophages affect the behavior of induced pluripotent stem cells (iPSCs) by generating three macrophage subtypes and assess their effects on the proliferation, cardiac differentiation, and maturation of iPSCs.
Mon Jul 18 00:00:00 EDT 2022
Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3.
Cell reports
Li Y,Zhu Y,Feng S,Ishida Y,Chiu TP,Saito T,Wang S,Ann DK,Ou JJ
200-04 was used in Cell Culture to report that M1-like macrophages stimulated by HBV exhibit a strong HBV-suppressive effect, which is diminished in M2-like macrophages.
Tue Jan 25 00:00:00 EST 2022
Human Mesenchymal Stem Cell Secretome Driven T Cell Immunomodulation Is IL-10 Dependent.
International journal of molecular sciences
Shephard MT,Merkhan MM,Forsyth NR
200-04 was used in In vitro experiments to investigate human mesenchymal stem cell secretions in treatment therapies.
Sun Nov 06 00:00:00 EDT 2022
Synthesis of bioactive (1→6)-β-glucose branched poly-amido-saccharides that stimulate and induce M1 polarization in macrophages.
Nature communications
Xiao R,Zeng J,Bressler EM,Lu W,Grinstaff MW
200-04 was used in In vitro experiments to proceed via the activation of NF-κB/AP-1 pathway in a Dectin-1-dependent manner, similar to natural β-glucans.
Tue Aug 09 00:00:00 EDT 2022
Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis.
JID innovations : skin science from molecules to population health
Niehues H,Rikken G,van Vlijmen-Willems IMJJ,Rodijk-Olthuis D,van Erp PEJ,Zeeuwen PLJM,Schalkwijk J,van den Bogaard EH
200-04 was used in In vitro experiments to investigate the mitogens involved in keratinocyte proliferation and stratification.
Sat Jan 01 00:00:00 EST 2022
Exosomes derived from M2 macrophages induce angiogenesis to promote wound healing.
Frontiers in molecular biosciences
Lyu L,Cai Y,Zhang G,Jing Z,Liang J,Zhang R,Dang X,Zhang C
200-04 was used in Cell Culture to demonstrate that M2-EXO can be used as a promising nanomedicine strategy for therapeutic exploration of skin healing with the potential to be translated into clinical practice.
Sat Oct 29 00:00:00 EDT 2022
Celastrol Downmodulates Alpha-Synuclein-Specific T Cell Responses by Mediating Antigen Trafficking in Dendritic Cells.
Frontiers in immunology
Ng L,Wang X,Yang C,Su C,Li M,Cheung AKL
200-04 was used in Cell Culture to conclude that regulating the intracellular trafficking/processing of α-syn by DCs can be a potential approach to control the progression of PD, in which Celastrol is a potential candidate to accomplish this.
Mon May 02 00:00:00 EDT 2022
Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors.
Cancer immunology research
Kim SP,Vale NR,Zacharakis N,Krishna S,Yu Z,Gasmi B,Gartner JJ,Sindiri S,Malekzadeh P,Deniger DC,Lowery FJ,Parkhurst MR,Ngo LT,Ray S,Li YF,Hill V,Florentin M,Masi RV,Paria BC,Levin N,Bera A,Hedges EA,Choi A,Chatani PD,Parikh AY,Levi S,Seitter S,Lu YC,Zheng Z,Prickett TD,Jia L,Hernandez JM,Hoang CD,Robbins PF,Goff SL,Sherry RM,Yang JC,Rosenberg SA
200-04 was used in Cell Culture to suggest that the library of TCRs targeting shared p53 neoantigens should be further evaluated for the treatment of patients with advanced human cancers.
Wed Aug 03 00:00:00 EDT 2022
Nocardia rubra cell-wall skeleton influences the development of cervical carcinoma by promoting the antitumor effect of macrophages and dendritic cells.
Cancer medicine
Zhang S,Wang H,Liu Y,Tao T,Zeng Z,Zhou Y,Wang M
200-04 was used in Cell Culture to suggest that Nr-CWS can promote apoptosis of cervical carcinoma cells by enhancing the antitumor effect of dendritic cells and macrophages.
Tue Mar 01 00:00:00 EST 2022
Indoleamine 2, 3-Dioxygenase 1 Mediates Survival Signals in Chronic Lymphocytic Leukemia via Kynurenine/Aryl Hydrocarbon Receptor-Mediated MCL1 Modulation.
Frontiers in immunology
Atene CG,Fiorcari S,Mesini N,Alboni S,Martinelli S,Maccaferri M,Leonardi G,Potenza L,Luppi M,Maffei R,Marasca R
200-04 was used in In vitro experiments to study the functional role of the IDO1/Kyn/AHR axis in chronic lymphocytic leukemia (CLL).
Fri Apr 08 00:00:00 EDT 2022
Tofacitinib-Induced Modulation of Intestinal Adaptive and Innate Immunity and Factors Driving Cellular and Systemic Pharmacokinetics.
Cellular and molecular gastroenterology and hepatology
Texler B,Zollner A,Reinstadler V,Reider SJ,Macheiner S,Jelusic B,Pfister A,Watschinger C,Przysiecki N,Tilg H,Oberacher H,Moschen AR
200-04 was used in In vitro experiments to describe an unappreciated mechanism-namely induction of equilibrative nucleoside transporters-enhancing baseline cellular uptake that can be inhibited pharmaceutically.
Mon Apr 04 00:00:00 EDT 2022
Differentiation and on axon-guidance chip culture of human pluripotent stem cell-derived peripheral cholinergic neurons for airway neurobiology studies.
Frontiers in pharmacology
Goldsteen PA,Sabogal Guaqueta AM,Mulder PPMFA,Bos IST,Eggens M,Van der Koog L,Soeiro JT,Halayko AJ,Mathwig K,Kistemaker LEM,Verpoorte EMJ,Dolga AM,Gosens R
200-04 was used in In vitro experiments to develop a microfluidic chip, to represent a human in vitro platform, to model neuro-effector interactions in the airways that may be used for mechanistic studies into neuroplasticity in asthma and other lung diseases.
Fri Nov 18 00:00:00 EST 2022
Single-cell RNA sequencing identifies a migratory keratinocyte subpopulation expressing THBS1 in epidermal wound healing.
iScience
Siriwach R,Ngo AQ,Higuchi M,Arima K,Sakamoto S,Watanabe A,Narumiya S,Thumkeo D
200-04 was used in Cell Culture to suggest that THBS1+ keratinocyte is a migratory keratinocyte subpopulation that facilitates epidermal wound healing.
Fri Apr 15 00:00:00 EDT 2022
MTAP loss correlates with an immunosuppressive profile in GBM and its substrate MTA stimulates alternative macrophage polarization.
Scientific reports
Hansen LJ,Yang R,Roso K,Wang W,Chen L,Yang Q,Pirozzi CJ,He Y
200-04 was used in Cell Culture to investigate methylthioadenosine phosphorylase expression in glioblastoma.
Wed Mar 09 00:00:00 EST 2022
MTAP loss correlates with an immunosuppressive profile in GBM and its substrate MTA stimulates alternative macrophage polarization.
Scientific reports
Hansen LJ,Yang R,Roso K,Wang W,Chen L,Yang Q,Pirozzi CJ,He Y
200-04 was used in Cell Culture to investigate methylthioadenosine phosphorylase expression in glioblastoma.
Wed Mar 09 00:00:00 EST 2022
Fam72a enforces error-prone DNA repair during antibody diversification.
Nature
Rogier M,Moritz J,Robert I,Lescale C,Heyer V,Abello A,Martin O,Capitani K,Thomas M,Thomas-Claudepierre AS,Laffleur B,Jouan F,Pinaud E,Tarte K,Cogné M,Conticello SG,Soutoglou E,Deriano L,Reina-San-Martin B
Wed Dec 01 00:00:00 EST 2021
The interferon landscape along the respiratory tract impacts the severity of COVID-19.
Cell
Sposito B,Broggi A,Pandolfi L,Crotta S,Clementi N,Ferrarese R,Sisti S,Criscuolo E,Spreafico R,Long JM,Ambrosi A,Liu E,Frangipane V,Saracino L,Bozzini S,Marongiu L,Facchini FA,Bottazzi A,Fossali T,Colombo R,Clementi M,Tagliabue E,Chou J,Pontiroli AE,Meloni F,Wack A,Mancini N,Zanoni I
Thu Sep 16 00:00:00 EDT 2021
Maturation and persistence of the anti-SARS-CoV-2 memory B cell response.
Cell
Sokal A,Chappert P,Barba-Spaeth G,Roeser A,Fourati S,Azzaoui I,Vandenberghe A,Fernandez I,Meola A,Bouvier-Alias M,Crickx E,Beldi-Ferchiou A,Hue S,Languille L,Michel M,Baloul S,Noizat-Pirenne F,Luka M,Mégret J,Ménager M,Pawlotsky JM,Fillatreau S,Rey FA,Weill JC,Reynaud CA,Mahévas M
Thu Mar 04 00:00:00 EST 2021
mRNA vaccination of naive and COVID-19-recovered individuals elicits potent memory B cells that recognize SARS-CoV-2 variants.
Immunity
Sokal A,Barba-Spaeth G,Fernández I,Broketa M,Azzaoui I,de La Selle A,Vandenberghe A,Fourati S,Roeser A,Meola A,Bouvier-Alias M,Crickx E,Languille L,Michel M,Godeau B,Gallien S,Melica G,Nguyen Y,Zarrouk V,Canoui-Poitrine F,Pirenne F,Mégret J,Pawlotsky JM,Fillatreau S,Bruhns P,Rey FA,Weill JC,Reynaud CA,Chappert P,Mahévas M
Tue Dec 14 00:00:00 EST 2021
Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes.
Immunity
Ehx G,Larouche JD,Durette C,Laverdure JP,Hesnard L,Vincent K,Hardy MP,Thériault C,Rulleau C,Lanoix J,Bonneil E,Feghaly A,Apavaloaei A,Noronha N,Laumont CM,Delisle JS,Vago L,Hébert J,Sauvageau G,Lemieux S,Thibault P,Perreault C
Tue Apr 13 00:00:00 EDT 2021
Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection.
Nature immunology
Munnur D,Teo Q,Eggermont D,Lee HHY,Thery F,Ho J,van Leur SW,Ng WWS,Siu LYL,Beling A,Ploegh H,Pinto-Fernandez A,Damianou A,Kessler B,Impens F,Mok CKP,Sanyal S
Mon Nov 01 00:00:00 EDT 2021
Selenium-GPX4 axis protects follicular helper T cells from ferroptosis.
Nature immunology
Yao Y,Chen Z,Zhang H,Chen C,Zeng M,Yunis J,Wei Y,Wan Y,Wang N,Zhou M,Qiu C,Zeng Q,Ong HS,Wang H,Makota FV,Yang Y,Yang Z,Wang N,Deng J,Shen C,Xia Y,Yuan L,Lian Z,Deng Y,Guo C,Huang A,Zhou P,Shi H,Zhang W,Yi H,Li D,Xia M,Fu J,Wu N,de Haan JB,Shen N,Zhang W,Liu Z,Yu D
Wed Sep 01 00:00:00 EDT 2021
Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes.
Cell stem cell
Shah PP,Lv W,Rhoades JH,Poleshko A,Abbey D,Caporizzo MA,Linares-Saldana R,Heffler JG,Sayed N,Thomas D,Wang Q,Stanton LJ,Bedi K,Morley MP,Cappola TP,Owens AT,Margulies KB,Frank DB,Wu JC,Rader DJ,Yang W,Prosser BL,Musunuru K,Jain R
200-04 was used in Cell Culture to show that pathogenic LAMIN A/C variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes.
Thu May 06 00:00:00 EDT 2021
Tetracyclines improve experimental lymphatic filariasis pathology by disrupting interleukin-4 receptor-mediated lymphangiogenesis.
The Journal of clinical investigation
Furlong-Silva J,Cross SD,Marriott AE,Pionnier N,Archer J,Steven A,Merker SS,Mack M,Hong YK,Taylor MJ,Turner JD
Mon Mar 01 00:00:00 EST 2021
Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus.
The Journal of clinical investigation
Vlahava VM,Murrell I,Zhuang L,Aicheler RJ,Lim E,Miners KL,Ladell K,Suárez NM,Price DA,Davison AJ,Wilkinson GW,Wills MR,Weekes MP,Wang EC,Stanton RJ
Mon Feb 15 00:00:00 EST 2021
TYRO3 induces anti-PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis.
The Journal of clinical investigation
Jiang Z,Lim SO,Yan M,Hsu JL,Yao J,Wei Y,Chang SS,Yamaguchi H,Lee HH,Ke B,Hsu JM,Chan LC,Hortobagyi GN,Yang L,Lin C,Yu D,Hung MC
Thu Apr 15 00:00:00 EDT 2021
Human skin is colonized by T cells that recognize CD1a independently of lipid.
The Journal of clinical investigation
Cotton RN,Cheng TY,Wegrecki M,Le Nours J,Orgill DP,Pomahac B,Talbot SG,Willis RA,Altman JD,de Jong A,Ogg G,Van Rhijn I,Rossjohn J,Clark RA,Moody DB
Mon Jan 04 00:00:00 EST 2021
Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice.
The Journal of experimental medicine
Pieters T,T'Sas S,Vanhee S,Almeida A,Driege Y,Roels J,Van Loocke W,Daneels W,Baens M,Marchand A,Van Trimpont M,Matthijssens F,Morscio J,Lemeire K,Lintermans B,Reunes L,Chaltin P,Offner F,Van Dorpe J,Hochepied T,Berx G,Beyaert R,Staal J,Van Vlierberghe P,Goossens S
Mon Oct 04 00:00:00 EDT 2021
T and B cell abnormalities, pneumocystis pneumonia, and chronic lymphocytic leukemia associated with an AIOLOS defect in patients.
The Journal of experimental medicine
Kuehn HS,Chang J,Yamashita M,Niemela JE,Zou C,Okuyama K,Harada J,Stoddard JL,Nunes-Santos CJ,Boast B,Baxter RM,Hsieh EWY,Garofalo M,Fleisher TA,Morio T,Taniuchi I,Dutmer CM,Rosenzweig SD
Mon Dec 06 00:00:00 EST 2021
Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients.
The Journal of experimental medicine
Lu X,Hosono Y,Nagae M,Ishizuka S,Ishikawa E,Motooka D,Ozaki Y,Sax N,Maeda Y,Kato Y,Morita T,Shinnakasu R,Inoue T,Onodera T,Matsumura T,Shinkai M,Sato T,Nakamura S,Mori S,Kanda T,Nakayama EE,Shioda T,Kurosaki T,Takeda K,Kumanogoh A,Arase H,Nakagami H,Yamashita K,Takahashi Y,Yamasaki S
Mon Dec 06 00:00:00 EST 2021
The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι.
Proceedings of the National Academy of Sciences of the United States of America
Zhang Y,Chen Y,Li Y,Huang F,Luo B,Yuan Y,Xia B,Ma X,Yang T,Yu F,Liu J,Liu B,Song Z,Chen J,Yan S,Wu L,Pan T,Zhang X,Li R,Huang W,He X,Xiao F,Zhang J,Zhang H
Tue Jun 08 00:00:00 EDT 2021
Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation.
Cell death and differentiation
Snodgrass RG,Benatzy Y,Schmid T,Namgaladze D,Mainka M,Schebb NH,Lütjohann D,Brüne B
Thu Apr 01 00:00:00 EDT 2021
The Fibronectin-ILT3 Interaction Functions as a Stromal Checkpoint that Suppresses Myeloid Cells.
Cancer immunology research
Paavola KJ,Roda JM,Lin VY,Chen P,O'Hollaren KP,Ventura R,Crawley SC,Li B,Chen HH,Malmersjö S,Sharkov NA,Horner G,Guo W,Kutach AK,Mondal K,Zhang Z,Lichtman JS,Song C,Rivera LB,Liu W,Luo J,Wang Y,Solloway MJ,Allan BB,Kekatpure A,Starck SR,Haldankar R,Fan B,Chu C,Tang J,Molgora M,Colonna M,Kaplan DD,Hsu JY
200-04 was used in In vitro experiments to show that, by blocking this interaction, tumor-associated myeloid cells may acquire a stimulatory phenotype, potentially resulting in increased antitumor T-cell responses.
Mon Nov 01 00:00:00 EDT 2021
lncRNA-Xist/miR-101-3p/KLF6/C/EBPα axis promotes TAM polarization to regulate cancer cell proliferation and migration.
Molecular therapy. Nucleic acids
Zhao Y,Yu Z,Ma R,Zhang Y,Zhao L,Yan Y,Lv X,Zhang L,Su P,Bi J,Xu H,He M,Wei M
Fri Mar 05 00:00:00 EST 2021
Severe Acute Respiratory Syndrome Coronavirus 2-Induced Immune Activation and Death of Monocyte-Derived Human Macrophages and Dendritic Cells.
The Journal of infectious diseases
Zheng J,Wang Y,Li K,Meyerholz DK,Allamargot C,Perlman S
Wed Mar 03 00:00:00 EST 2021
Mantle cell lymphoma polarizes tumor-associated macrophages into M2-like macrophages, which in turn promote tumorigenesis.
Blood advances
Le K,Sun J,Khawaja H,Shibata M,Maggirwar SB,Smith MR,Gupta M
Tue Jul 27 00:00:00 EDT 2021
CXCL5 secreted from macrophages during cold exposure mediates white adipose tissue browning.
Journal of lipid research
Lee D,Kim DW,Yoon S,Nam AR,Lee KH,Nam KH,Cho SM,Yoon Y,Cho JY
Thu Mar 24 00:00:00 EDT 2022
Enhanced Uptake of Processed Bovine β-Lactoglobulin by Antigen Presenting Cells: Identification of Receptors and Implications for Allergenicity.
Molecular nutrition & food research
Teodorowicz M,Zenker HE,Ewaz A,Tsallis T,Mauser A,Gensberger-Reigl S,de Jong NW,Hettinga KA,Wichers HJ,van Neerven RJJ,Savelkoul HFJ
Thu Apr 01 00:00:00 EDT 2021
Combination of tumor necrosis factor-α and epidermal growth factor induces the adrenergic-to-mesenchymal transdifferentiation in SH-SY5Y neuroblastoma cells.
Cancer science
Huang Y,Tsubota S,Nishio N,Takahashi Y,Kadomatsu K
200-04 was used in Cell Culture to propose a mechanism of neuroblastoma transdifferentiation induced by extracellular growth factors, which can be controlled in clinical situations, providing a new therapeutic possibility.
Mon Feb 01 00:00:00 EST 2021
Combination of tumor necrosis factor-α and epidermal growth factor induces the adrenergic-to-mesenchymal transdifferentiation in SH-SY5Y neuroblastoma cells.
Cancer science
Huang Y,Tsubota S,Nishio N,Takahashi Y,Kadomatsu K
200-04 was used in Cell Culture to propose a mechanism of neuroblastoma transdifferentiation induced by extracellular growth factors, which can be controlled in clinical situations, providing a new therapeutic possibility.
Mon Feb 01 00:00:00 EST 2021
Systemic immunity upon local oncolytic virotherapy armed with immunostimulatory genes may be supported by tumor-derived exosomes.
Molecular therapy oncolytics
Labani-Motlagh A,Naseri S,Wenthe J,Eriksson E,Loskog A
Fri Mar 26 00:00:00 EDT 2021
Mycobacterium leprae induces a tolerogenic profile in monocyte-derived dendritic cells via TLR2 induction of IDO.
Journal of leukocyte biology
Oliveira JAP,Gandini M,Sales JS,Fujimori SK,Barbosa MGM,Frutuoso VS,Moraes MO,Sarno EN,Pessolani MCV,Pinheiro RO
Thu Jul 01 00:00:00 EDT 2021
TPL Inhibits the Invasion and Migration of Drug-Resistant Ovarian Cancer by Targeting the PI3K/AKT/NF-κB-Signaling Pathway to Inhibit the Polarization of M2 TAMs.
Frontiers in oncology
Le F,Yang L,Han Y,Zhong Y,Zhan F,Feng Y,Hu H,Chen T,Tan B
200-04 was used in Cell Culture to highlight the importance of M2 TAMs in Epithelial Ovarian Cancer (EOC) migration ability, invasiveness, and resistance to DDP.
Fri Aug 13 00:00:00 EDT 2021
IL-21 Is an Accomplice of PD-L1 in the Induction of PD-1-Dependent Treg Generation in Head and Neck Cancer.
Frontiers in oncology
Zhao Y,Zhang Z,Lei W,Wei Y,Ma R,Wen Y,Wei F,Fan J,Xu Y,Chen L,Lyu K,Lin H,Wen W,Sun W
200-04 was used in Cell Culture to study that IL-21 could promote PD-L1-induced Treg generation in a PD-1-dependent manner.
Wed May 26 00:00:00 EDT 2021
T Cells Specific for a Mycobacterial Glycolipid Expand after Intravenous Bacillus Calmette-Guérin Vaccination.
Journal of immunology (Baltimore, Md. : 1950)
Layton ED,Barman S,Wilburn DB,Yu KKQ,Smith MT,Altman JD,Scriba TJ,Tahiri N,Minnaard AJ,Roederer M,Seder RA,Darrah PA,Seshadri C
Mon Mar 15 00:00:00 EDT 2021
Proinflammatory Features of Stem Cell-like Memory T Cells from Human Patients with Rheumatoid Arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Lee YJ,Park EH,Park JW,Jung KC,Lee EB
Thu Jul 15 00:00:00 EDT 2021
CD40L-Stimulated B Lymphocytes Are Polarized toward APC Functions after Exposure to IL-4 and IL-21.
Journal of immunology (Baltimore, Md. : 1950)
Possamaï D,Pagé G,Panès R,Gagnon É,Lapointe R
Thu Jul 01 00:00:00 EDT 2021
Human Inflammatory Neutrophils Express Genes Encoding Peptidase Inhibitors: Production of Elafin Mediated by NF-κB and CCAAT/Enhancer-Binding Protein β.
Journal of immunology (Baltimore, Md. : 1950)
Allaeys I,Ribeiro de Vargas F,Bourgoin SG,Poubelle PE
Thu Apr 15 00:00:00 EDT 2021
The Zinc Finger Protein Zbtb18 Represses Expression of Class I Phosphatidylinositol 3-Kinase Subunits and Inhibits Plasma Cell Differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Xie B,Khoyratty TE,Abu-Shah E,F Cespedes P,MacLean AJ,Pirgova G,Hu Z,Ahmed AA,Dustin ML,Udalova IA,Arnon TI
Thu Apr 01 00:00:00 EDT 2021
Selective inhibition of prostaglandin D2 biosynthesis in human mast cells to overcome need for multiple receptor antagonists: Biochemical consequences.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Johnsson AK,Choi JH,Rönnberg E,Fuchs D,Kolmert J,Hamberg M,Dahlén B,Wheelock CE,Dahlén SE,Nilsson G
Thu Apr 01 00:00:00 EDT 2021
Dendritic cells loaded with exosomes derived from cancer stem cell-enriched spheroids as a potential immunotherapeutic option.
Journal of cellular and molecular medicine
Naseri M,Zöller M,Hadjati J,Ghods R,Ranaei Pirmardan E,Kiani J,Eini L,Bozorgmehr M,Madjd Z
Thu Apr 01 00:00:00 EDT 2021
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Journal of cellular and molecular medicine
Hu J,Wang J,Li C,Shang Y
Tue Jun 01 00:00:00 EDT 2021
Histone deacetylase 9 deficiency exaggerates uterine M2 macrophage polarization.
Journal of cellular and molecular medicine
Liu Y,Du M,Lin HY
Sun Aug 01 00:00:00 EDT 2021
HLA DR Genome Editing with TALENs in Human iPSCs Produced Immune-Tolerant Dendritic Cells.
Stem cells international
Kwon YW,Ahn HS,Lee JW,Yang HM,Cho HJ,Kim SJ,Lee SH,Yang HM,Jang HD,Kim SJ,Kim HS
Tue Jun 08 00:00:00 EDT 2021
Rapid generation of monocyte-derived antigen-presenting cells with dendritic cell-like properties.
Transfusion
Cunningham S,Hackstein H
Tue Jun 01 00:00:00 EDT 2021
Endocytosed nanogold fiducials for improved in-situ cryo-electron tomography tilt-series alignment.
Journal of structural biology
Berger C,Ravelli RBG,López-Iglesias C,Peters PJ
200-04 was used in Cell Culture to describe a method to allow uptake of bovine serum albumin (BSA)-gold fiducials into mammalian cells via endocytosis, which can subsequently be used as fiducials for tilt-series alignment of cryo-focused ion beam (FIB) lamellae.
Mon Mar 01 00:00:00 EST 2021
ZEB1 promotes pathogenic Th1 and Th17 cell differentiation in multiple sclerosis.
Cell reports
Qian Y,Arellano G,Ifergan I,Lin J,Snowden C,Kim T,Thomas JJ,Law C,Guan T,Balabanov RD,Kaech SM,Miller SD,Choi J
Tue Aug 24 00:00:00 EDT 2021
Ruxolitinib inhibits poly(I:C) and type 2 cytokines-induced CCL5 production in bronchial epithelial cells: A potential therapeutic agent for severe eosinophilic asthma.
Immunity, inflammation and disease
Sada M,Watanabe M,Inui T,Nakamoto K,Hirata A,Nakamura M,Honda K,Saraya T,Kurai D,Kimura H,Ishii H,Takizawa H
Tue Jun 01 00:00:00 EDT 2021
Sunitinib Combined with Th1 Cytokines Potentiates Apoptosis in Human Breast Cancer Cells and Suppresses Tumor Growth in a Murine Model of HER-2pos Breast Cancer.
International journal of breast cancer
Ghimirey N,Steele C,Czerniecki BJ,Koski GK,Showalter LE
Tue May 04 00:00:00 EDT 2021
SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression.
Nature communications
Hou G,Harley ITW,Lu X,Zhou T,Xu N,Yao C,Qin Y,Ouyang Y,Ma J,Zhu X,Yu X,Xu H,Dai D,Ding H,Yin Z,Ye Z,Deng J,Zhou M,Tang Y,Namjou B,Guo Y,Weirauch MT,Kottyan LC,Harley JB,Shen N
Fri Jan 08 00:00:00 EST 2021
Implication of TIGIT+ human memory B cells in immune regulation.
Nature communications
Hasan MM,Nair SS,O'Leary JG,Thompson-Snipes L,Nyarige V,Wang J,Park W,Stegall M,Heilman R,Klintmalm GB,Joo H,Oh S
Tue Mar 09 00:00:00 EST 2021
Inhibition of galectin-3 augments the antitumor efficacy of PD-L1 blockade in non-small-cell lung cancer.
FEBS open bio
Zhang H,Liu P,Zhang Y,Han L,Hu Z,Cai Z,Cai J
Mon Mar 01 00:00:00 EST 2021
The miR-424(322)/503 gene cluster regulates pro- versus anti-inflammatory skin DC subset differentiation by modulating TGF-β signaling.
Cell reports
Zyulina V,Yan KK,Ju B,Schwarzenberger E,Passegger C,Tam-Amersdorfer C,Pan Q,Sconocchia T,Pollack C,Shaner B,Zebisch A,Easton J,Yu J,Silva JM,Strobl H
Tue Apr 27 00:00:00 EDT 2021
Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling.
Cell reports
Trauelsen M,Hiron TK,Lin D,Petersen JE,Breton B,Husted AS,Hjorth SA,Inoue A,Frimurer TM,Bouvier M,O'Callaghan CA,Schwartz TW
Tue Jun 15 00:00:00 EDT 2021
IL-25 Induced ROS-Mediated M2 Macrophage Polarization via AMPK-Associated Mitophagy.
International journal of molecular sciences
Tsai ML,Tsai YG,Lin YC,Hsu YL,Chen YT,Tsai MK,Liao WT,Lin YC,Hung CH
200-04 was used in Cell Culture to induce mitophagy to stimulate M2 macrophage polarization in monocytes.
Tue Dec 21 00:00:00 EST 2021
Pseurotin D Inhibits the Activation of Human Lymphocytes.
International journal of molecular sciences
Rubanova D,Dadova P,Vasicek O,Kubala L
200-04 was used in Cell Culture to perform complex characterization of the effects of pseurotin D on human lymphocyte activation to understand the potential of pseurotin to modulate immune response in humans.
Tue Feb 16 00:00:00 EST 2021
Severe T cell hyporeactivity in ventilated COVID-19 patients correlates with prolonged virus persistence and poor outcomes.
Nature communications
Renner K,Schwittay T,Chaabane S,Gottschling J,Müller C,Tiefenböck C,Salewski JN,Winter F,Buchtler S,Balam S,Malfertheiner MV,Lubnow M,Lunz D,Graf B,Hitzenbichler F,Hanses F,Poeck H,Kreutz M,Orsó E,Burkhardt R,Niedermair T,Brochhausen C,Gessner A,Salzberger B,Mack M
Fri May 21 00:00:00 EDT 2021
A novel, multitargeted endogenous metabolic modulator composition impacts metabolism, inflammation, and fibrosis in nonalcoholic steatohepatitis-relevant primary human cell models.
Scientific reports
Daou N,Viader A,Cokol M,Nitzel A,Chakravarthy MV,Afeyan R,Tramontin T,Marukian S,Hamill MJ
Fri Jun 04 00:00:00 EDT 2021
Titanium Nanoparticles Enhance Production and Suppress Stabilin-1-Mediated Clearance of GDF-15 in Human Primary Macrophages.
Frontiers in immunology
Silva-Bermudez LS,Sevastyanova TN,Schmuttermaier C,De La Torre C,Schumacher L,Klüter H,Kzhyshkowska J
200-04 was used in In vitro experiments to study how titanium nanoparticles (TiNPs) affect the healing activities of macrophages and their release of circulating cytokines to identify the transcriptional program induced and suppressed by TiNPs in human pro-inflammatory and healing macrophages.
Wed Feb 16 00:00:00 EST 2022
M2a Macrophage-Secreted CHI3L1 Promotes Extracellular Matrix Metabolic Imbalances via Activation of IL-13Rα2/MAPK Pathway in Rat Intervertebral Disc Degeneration.
Frontiers in immunology
Li L,Wei K,Ding Y,Ahati P,Xu H,Fang H,Wang H
200-04 was used in Cell Culture to investigate M2a expression during intervertebral disc degeneration.
Thu Oct 14 00:00:00 EDT 2021
Novel oncolytic adenovirus expressing enhanced cross-hybrid IgGA Fc PD-L1 inhibitor activates multiple immune effector populations leading to enhanced tumor killing in vitro, in vivo and with patient-derived tumor organoids.
Journal for immunotherapy of cancer
Hamdan F,Ylösmäki E,Chiaro J,Giannoula Y,Long M,Fusciello M,Feola S,Martins B,Feodoroff M,Antignani G,Russo S,Kari O,Lee M,Järvinen P,Nisen H,Kreutzman A,Leusen J,Mustjoki S,McWilliams TG,Grönholm M,Cerullo V
200-04 was used in Cell Culture to designed an oncolytic adenovirus to increase efficacy while minimizing toxicity of PD-L1 immunecheckpoint therapy that secretes a cross-hybrid Fc-fusion peptide against PD-L1 able to elicit effector mechanisms of an IgG1 and also IgA1 consequently activating neutrophils, a population neglected by IgG1, in order to combine multiple effector mechanisms.
Sun Aug 01 00:00:00 EDT 2021
Identification of HLA-A2-Restricted Mutant Epitopes from Neoantigens of Esophageal Squamous Cell Carcinoma.
Vaccines
Wang Z,Ran L,Chen C,Shi R,Dong Y,Li Y,Zhou X,Qi Y,Zhu P,Gao Y,Wu Y
200-04 was used in Sample Preparation (FC/FACS) to investigate treatment for esophageal squamous cell carcinoma.
Fri Oct 01 00:00:00 EDT 2021
Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling.
Nature communications
Wang J,Wang J,Hong W,Zhang L,Song L,Shi Q,Shao Y,Hao G,Fang C,Qiu Y,Yang L,Yang Z,Wang J,Cao J,Yang B,He Q,Weng Q
Wed Oct 27 00:00:00 EDT 2021
Tumor cytotoxicity and immunogenicity of a novel V-jet neon plasma source compared to the kINPen.
Scientific reports
Miebach L,Freund E,Horn S,Niessner F,Sagwal SK,von Woedtke T,Emmert S,Weltmann KD,Clemen R,Schmidt A,Gerling T,Bekeschus S
Fri Jan 08 00:00:00 EST 2021
Functional and genomic adaptations of blood monocytes to pregravid obesity during pregnancy.
iScience
Sureshchandra S,Marshall NE,Mendoza N,Jankeel A,Zulu MZ,Messaoudi I
Fri Jun 25 00:00:00 EDT 2021
Biomimetic Anti-PD-1 Peptide-Loaded 2D FePSe3 Nanosheets for Efficient Photothermal and Enhanced Immune Therapy with Multimodal MR/PA/Thermal Imaging.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Fang X,Wu X,Li Z,Jiang L,Lo WS,Chen G,Gu Y,Wong WT
Fri Jan 01 00:00:00 EST 2021
Chemotherapy agents stimulate dendritic cells against human colon cancer cells through upregulation of the transporter associated with antigen processing.
Scientific reports
Liang YH,Tsai JH,Cheng YM,Chan KY,Hsu WL,Lee CC,Chen KH,Yeh KH
Tue Apr 27 00:00:00 EDT 2021
Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors.
Cell reports. Medicine
Kosti P,Opzoomer JW,Larios-Martinez KI,Henley-Smith R,Scudamore CL,Okesola M,Taher MYM,Davies DM,Muliaditan T,Larcombe-Young D,Woodman N,Gillett CE,Thavaraj S,Maher J,Arnold JN
Tue Apr 20 00:00:00 EDT 2021
Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity.
Cell reports
Szodoray P,Andersen TK,Heinzelbecker J,Imbery JF,Huszthy PC,Stanford SM,Bogen B,Landsverk OB,Bottini N,Tveita A,Munthe LA,Nakken B
Tue Aug 10 00:00:00 EDT 2021
Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy.
Nature communications
Wang YC,Wang X,Yu J,Ma F,Li Z,Zhou Y,Zeng S,Ma X,Li YR,Neal A,Huang J,To A,Clarke N,Memarzadeh S,Pellegrini M,Yang L
Thu Jun 10 00:00:00 EDT 2021
Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants.
Communications biology
Cavarelli M,Hua S,Hantour N,Tricot S,Tchitchek N,Gommet C,Hocini H,Chapon C,Dereuddre-Bosquet N,Le Grand R
Mon Jul 12 00:00:00 EDT 2021
Distinct uptake, amplification, and release of SARS-CoV-2 by M1 and M2 alveolar macrophages.
Cell discovery
Lv J,Wang Z,Qu Y,Zhu H,Zhu Q,Tong W,Bao L,Lv Q,Cong J,Li D,Deng W,Yu P,Song J,Tong WM,Liu J,Liu Y,Qin C,Huang B
Tue Apr 13 00:00:00 EDT 2021
SARS-CoV-2 Induces Lymphocytopenia by Promoting Inflammation and Decimates Secondary Lymphoid Organs.
Frontiers in immunology
Xiang Q,Feng Z,Diao B,Tu C,Qiao Q,Yang H,Zhang Y,Wang G,Wang H,Wang C,Liu L,Wang C,Liu L,Chen R,Wu Y,Chen Y
200-04 was used in In vitro experiments to demonstrate that SARS-CoV-2 induced lymphocytopenia by promoting systemic inflammation and direct neutralization in human spleen and LNs.
Tue May 25 00:00:00 EDT 2021
Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice.
Nature communications
Conde E,Bertrand R,Balbino B,Bonnefoy J,Stackowicz J,Caillot N,Colaone F,Hamdi S,Houmadi R,Loste A,Kamphuis JBJ,Huetz F,Guilleminault L,Gaudenzio N,Mougel A,Hardy D,Snouwaert JN,Koller BH,Serra V,Bruhns P,Grouard-Vogel G,Reber LL
Tue May 11 00:00:00 EDT 2021
Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression.
Nature communications
Bolis M,Bossi D,Vallerga A,Ceserani V,Cavalli M,Impellizzieri D,Di Rito L,Zoni E,Mosole S,Elia AR,Rinaldi A,Pereira Mestre R,D'Antonio E,Ferrari M,Stoffel F,Jermini F,Gillessen S,Bubendorf L,Schraml P,Calcinotto A,Corey E,Moch H,Spahn M,Thalmann G,Kruithof-de Julio M,Rubin MA,Theurillat JP
200-04 was used in In vitro experiments to provide a user-friendly web-resource enabling the investigation of dynamic transcriptional perturbations linked to disease progression.
Thu Dec 02 00:00:00 EST 2021
Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis.
Nature communications
Andres-Ejarque R,Ale HB,Grys K,Tosi I,Solanky S,Ainali C,Catak Z,Sreeneebus H,Saklatvala J,Dand N,de Rinaldis E,Chapman A,Nestle FO,Barnes MR,Warren RB,Reynolds NJ,Griffiths CEM,Barker JN,Smith CH,Di Meglio P
Fri Aug 06 00:00:00 EDT 2021
Regulatory T cells induce polarization of pro-repair macrophages by secreting sFGL2 into the endometriotic milieu.
Communications biology
Hou XX,Wang XQ,Zhou WJ,Li DJ
Fri Apr 23 00:00:00 EDT 2021
PLGA-particle vaccine carrying TLR3/RIG-I ligand Riboxxim synergizes with immune checkpoint blockade for effective anti-cancer immunotherapy.
Nature communications
Koerner J,Horvath D,Herrmann VL,MacKerracher A,Gander B,Yagita H,Rohayem J,Groettrup M
200-04 was used in Cell Culture to demonstrate the supreme adjuvant effect of the recently developed and pharmaceutically defined double-stranded (ds)RNA adjuvant Riboxxim especially when incorporated into PLGA particles.
Tue May 18 00:00:00 EDT 2021
Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D.
The Journal of clinical investigation
Zheng J,Meyerholz D,Wong LR,Gelb M,Murakami M,Perlman S
Tue Jun 01 00:00:00 EDT 2021
High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming.
Nature communications
Hu G,Su Y,Kang BH,Fan Z,Dong T,Brown DR,Cheah J,Wittrup KD,Chen J
Wed Feb 03 00:00:00 EST 2021
PD-1 Affects the Immunosuppressive Function of Group 2 Innate Lymphoid Cells in Human Non-Small Cell Lung Cancer.
Frontiers in immunology
Shen C,Liu C,Zhang Z,Ping Y,Shao J,Tian Y,Yu W,Qin G,Liu S,Wang L,Zhang Y
200-04 was used in Sample Preparation (FC/FACS) to show that ILC2s are enriched in NSCLC patients and upregulate PD-1 expression.
Mon Oct 25 00:00:00 EDT 2021
Anti-Cancer Activity Profiling of Chemotherapeutic Agents in 3D Co-Cultures of Pancreatic Tumor Spheroids with Cancer-Associated Fibroblasts and Macrophages.
Cancers
Jang SD,Song J,Kim HA,Im CN,Khawar IA,Park JK,Kuh HJ
200-04 was used in Cell Culture to analyse the anti-cancer effects of activated pancreatic stellate cells and M2 macrophages in pancreatic ductal adenocarcinoma.
Fri Nov 26 00:00:00 EST 2021
Identification of poly(ADP-ribose) polymerase 9 (PARP9) as a noncanonical sensor for RNA virus in dendritic cells.
Nature communications
Xing J,Zhang A,Du Y,Fang M,Minze LJ,Liu YJ,Li XC,Zhang Z
200-04 was used in Cell Culture to investigate the role of poly(ADP-ribose) polymerase 9 on type I IFN production in dendritic cells.
Tue May 11 00:00:00 EDT 2021
Identification of poly(ADP-ribose) polymerase 9 (PARP9) as a noncanonical sensor for RNA virus in dendritic cells.
Nature communications
Xing J,Zhang A,Du Y,Fang M,Minze LJ,Liu YJ,Li XC,Zhang Z
200-04 was used in Cell Culture to investigate the role of poly(ADP-ribose) polymerase 9 on type I IFN production in dendritic cells.
Tue May 11 00:00:00 EDT 2021
Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period.
Frontiers in immunology
Ji WH,Li DD,Wei DP,Gu AQ,Yang Y,Peng JP
200-04 was used in Cell Culture to investigate whether Cytochrome P450 26A1 (CYP26A1) regulates the polarization of uterine macrophages in early pregnancy.
Thu Feb 10 00:00:00 EST 2022
Ultra-purification of Lipopolysaccharides reveals species-specific signalling bias of TLR4: importance in macrophage function.
Scientific reports
Stephens M,Liao S,von der Weid PY
Thu Jan 14 00:00:00 EST 2021
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation.
Science immunology
Niyonzima N,Rahman J,Kunz N,West EE,Freiwald T,Desai JV,Merle NS,Gidon A,Sporsheim B,Lionakis MS,Evensen K,Lindberg B,Skagen K,Skjelland M,Singh P,Haug M,Ruseva MM,Kolev M,Bibby J,Marshall O,O'Brien B,Deeks N,Afzali B,Clark RJ,Woodruff TM,Pryor M,Yang ZH,Remaley AT,Mollnes TE,Hewitt SM,Yan B,Kazemian M,Kiss MG,Binder CJ,Halvorsen B,Espevik T,Kemper C
200-04 was used in Sample Preparation (Western Blotting) to suggest that the complosome is a contributor to the biologic processes underlying sterile inflammation and indicate that targeting this system could be beneficial in macrophage-dependent diseases, such as atherosclerosis.
Fri Dec 24 00:00:00 EST 2021
Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity.
Cell
Lu Y,Zhao Q,Liao JY,Song E,Xia Q,Pan J,Li Y,Li J,Zhou B,Ye Y,Di C,Yu S,Zeng Y,Su S
Thu Mar 19 00:00:00 EDT 2020
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.
Cell
Blanco-Melo D,Nilsson-Payant BE,Liu WC,Uhl S,Hoagland D,Møller R,Jordan TX,Oishi K,Panis M,Sachs D,Wang TT,Schwartz RE,Lim JK,Albrecht RA,tenOever BR
Thu May 28 00:00:00 EDT 2020
Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans.
Cell
Ha CWY,Martin A,Sepich-Poore GD,Shi B,Wang Y,Gouin K,Humphrey G,Sanders K,Ratnayake Y,Chan KSL,Hendrick G,Caldera JR,Arias C,Moskowitz JE,Ho Sui SJ,Yang S,Underhill D,Brady MJ,Knott S,Kaihara K,Steinbaugh MJ,Li H,McGovern DPB,Knight R,Fleshner P,Devkota S
Thu Oct 29 00:00:00 EDT 2020
Tumor-Derived Retinoic Acid Regulates Intratumoral Monocyte Differentiation to Promote Immune Suppression.
Cell
Devalaraja S,To TKJ,Folkert IW,Natesan R,Alam MZ,Li M,Tada Y,Budagyan K,Dang MT,Zhai L,Lobel GP,Ciotti GE,Eisinger-Mathason TSK,Asangani IA,Weber K,Simon MC,Haldar M
200-04 was used in In vitro experiments to find that the TME induces tumor cells to produce retinoic acid (RA), which polarizes intratumoral monocyte differentiation toward TAMs and away from DCs via suppression of DC-promoting transcription factor Irf4.
Thu Mar 19 00:00:00 EDT 2020
Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses.
Immunity
Ma X,Zou F,Yu F,Li R,Yuan Y,Zhang Y,Zhang X,Deng J,Chen T,Song Z,Qiao Y,Zhan Y,Liu J,Zhang J,Zhang X,Peng Z,Li Y,Lin Y,Liang L,Wang G,Chen Y,Chen Q,Pan T,He X,Zhang H
200-04 was used in Flow cytometry/Cell sorting to develop nanoparticle vaccines by covalently conjugating the self-assembled 24-mer ferritin to the receptor binding domain (RBD) and/or heptad repeat (HR) subunits of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) spike (S) protein.
Tue Dec 15 00:00:00 EST 2020
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion.
Cancer cell
Su R,Dong L,Li Y,Gao M,Han L,Wunderlich M,Deng X,Li H,Huang Y,Gao L,Li C,Zhao Z,Robinson S,Tan B,Qing Y,Qin X,Prince E,Xie J,Qin H,Li W,Shen C,Sun J,Kulkarni P,Weng H,Huang H,Chen Z,Zhang B,Wu X,Olsen MJ,Müschen M,Marcucci G,Salgia R,Li L,Fathi AT,Li Z,Mulloy JC,Wei M,Horne D,Chen J
200-04 was used in In vitro experiments to demonstrate if fat mass and obesity-associated protein plays critical roles in cancer stem cell self-renewal and immune evasion.
Mon Jul 13 00:00:00 EDT 2020
JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation.
Blood
Meyer LK,Verbist KC,Albeituni S,Scull BP,Bassett RC,Stroh AN,Tillman H,Allen CE,Hermiston ML,Nichols KE
Thu Aug 06 00:00:00 EDT 2020
mRNA vaccine-induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer.
The Journal of clinical investigation
Cafri G,Gartner JJ,Zaks T,Hopson K,Levin N,Paria BC,Parkhurst MR,Yossef R,Lowery FJ,Jafferji MS,Prickett TD,Goff SL,McGowan CT,Seitter S,Shindorf ML,Parikh A,Chatani PD,Robbins PF,Rosenberg SA
Mon Nov 02 00:00:00 EST 2020
Trans-endocytosis of intact IL-15Rα-IL-15 complex from presenting cells into NK cells favors signaling for proliferation.
Proceedings of the National Academy of Sciences of the United States of America
Anton OM,Peterson ME,Hollander MJ,Dorward DW,Arora G,Traba J,Rajagopalan S,Snapp EL,Garcia KC,Waldmann TA,Long EO
Tue Jan 07 00:00:00 EST 2020
A mutation in POLR3E impairs antiviral immune response and RNA polymerase III.
Proceedings of the National Academy of Sciences of the United States of America
Ramanathan A,Weintraub M,Orlovetskie N,Serruya R,Mani D,Marcu O,Stepensky P,Weisblum Y,Djian E,Shaag A,Revel-Vilk S,Fried I,Kotler M,Rouvinski A,Wolf D,Elpeleg O,Jarrous N
Tue Sep 08 00:00:00 EDT 2020
Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease.
Proceedings of the National Academy of Sciences of the United States of America
Preciado-Llanes L,Aulicino A,Canals R,Moynihan PJ,Zhu X,Jambo N,Nyirenda TS,Kadwala I,Sousa Gerós A,Owen SV,Jambo KC,Kumwenda B,Veerapen N,Besra GS,Gordon MA,Hinton JCD,Napolitani G,Salio M,Simmons A
Tue Aug 25 00:00:00 EDT 2020
Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism.
Proceedings of the National Academy of Sciences of the United States of America
Cribbs AP,Terlecki-Zaniewicz S,Philpott M,Baardman J,Ahern D,Lindow M,Obad S,Oerum H,Sampey B,Mander PK,Penn H,Wordsworth P,Bowness P,de Winther M,Prinjha RK,Feldmann M,Oppermann U
Tue Mar 17 00:00:00 EDT 2020
Breast cancer-associated macrophages promote tumorigenesis by suppressing succinate dehydrogenase in tumor cells.
Science signaling
Gómez V,Eykyn TR,Mustapha R,Flores-Borja F,Male V,Barber PR,Patsialou A,Green R,Panagaki F,Li CW,Fruhwirth GO,Ros S,Brindle KM,Ng T
Tue Oct 06 00:00:00 EDT 2020
High-grade mesenchymal pancreatic ductal adenocarcinoma drives stromal deactivation through CSF-1.
EMBO reports
Steins A,van Mackelenbergh MG,van der Zalm AP,Klaassen R,Serrels B,Goris SG,Kocher HM,Waasdorp C,de Jong JH,Tekin C,Besselink MG,Busch OR,van de Vijver MJ,Verheij J,Dijk F,van Tienhoven G,Wilmink JW,Medema JP,van Laarhoven HW,Bijlsma MF
Wed May 06 00:00:00 EDT 2020
Identification of tumor-associated macrophage subsets that are associated with breast cancer prognosis.
Clinical and translational medicine
Strack E,Rolfe PA,Fink AF,Bankov K,Schmid T,Solbach C,Savai R,Sha W,Pradel L,Hartmann S,Brüne B,Weigert A
Tue Dec 01 00:00:00 EST 2020
Identification of two HLA-A*0201 immunogenic epitopes of lactate dehydrogenase C (LDHC): potential novel targets for cancer immunotherapy.
Cancer immunology, immunotherapy : CII
Thomas R,Shaath H,Naik A,Toor SM,Elkord E,Decock J
200-04 was used in In vitro experiments to investigate the immunogenicity of LDHC using T cells from healthy individuals.
Sun Mar 01 00:00:00 EST 2020
Reciprocal Interplay Between Astrocytes and CD4+ Cells Affects Blood-Brain Barrier and Neuronal Function in Response to β Amyloid.
Frontiers in molecular neuroscience
Spampinato SF,Merlo S,Fagone E,Fruciano M,Sano Y,Kanda T,Sortino MA
200-04 was used in Cell Culture to show reciprocal crosstalk between infiltrating peripheral cells and astrocytes upon Aβ exposure.
Mon Sep 28 00:00:00 EDT 2020
Resident alveolar macrophage-derived vesicular SOCS3 dampens allergic airway inflammation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Draijer C,Speth JM,Penke LRK,Zaslona Z,Bazzill JD,Lugogo N,Huang YJ,Moon JJ,Peters-Golden M
Sun Mar 01 00:00:00 EST 2020
A human co-culture cell model incorporating microglia supports glioblastoma growth and migration, and confers resistance to cytotoxics.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Leite DM,Zvar Baskovic B,Civita P,Neto C,Gumbleton M,Pilkington GJ
Wed Jan 01 00:00:00 EST 2020
Activation of Human Vδ2+ γδ T Cells by Staphylococcus aureus Promotes Enhanced Anti-Staphylococcal Adaptive Immunity.
Journal of immunology (Baltimore, Md. : 1950)
Cooper AJR,Lalor SJ,McLoughlin RM
Sat Aug 15 00:00:00 EDT 2020
Homeostatic Milieu Induces Production of Deoxyribonuclease 1-like 3 from Myeloid Cells.
Journal of immunology (Baltimore, Md. : 1950)
Inokuchi S,Mitoma H,Kawano S,Nakano S,Ayano M,Kimoto Y,Akahoshi M,Arinobu Y,Tsukamoto H,Akashi K,Horiuchi T,Niiro H
Wed Apr 15 00:00:00 EDT 2020
Human CD8+ T Cells Exhibit a Shared Antigen Threshold for Different Effector Responses.
Journal of immunology (Baltimore, Md. : 1950)
Abu-Shah E,Trendel N,Kruger P,Nguyen J,Pettmann J,Kutuzov M,Dushek O
Tue Sep 15 00:00:00 EDT 2020
MRGPRX2 activation as a rapid, high-throughput mechanistic-based approach for detecting peptide-mediated human mast cell degranulation liabilities.
Journal of immunotoxicology
Lafleur MA,Werner J,Fort M,Lobenhofer EK,Balazs M,Goyos A
200-04 was used in Sample Preparation (FC/FACS) to investigate the use of assessing MRGPRX2 activation in engineered cells in screening for mast cell degranulation for peptide-based therapeutics.
Tue Dec 01 00:00:00 EST 2020
Inhibition of thymic stromal lymphopoietin production to improve pruritus and quality of life in infants and children with atopic dermatitis.
Journal of cosmetic dermatology
Fitoussi J,Virassamynaïk S,Callejon S,Weber S,Collet E,Scalia J,Chavagnac-Bonneville M,Trompezinski S,Sayag M
Sat Aug 01 00:00:00 EDT 2020
hESC-derived immune suppressive dendritic cells induce immune tolerance of parental hESC-derived allografts.
EBioMedicine
Todorova D,Zhang Y,Chen Q,Liu J,He J,Fu X,Xu Y
200-04 was used in Cell Culture to investigate whether the adoptive transfer of CTLA4-Ig/PD-L1 knock-in dendritic cell-like cells(CP DCLs) can induce long-term immune tolerance of parental human embryonic stem cells(hESC)-derived smooth muscle and cardiomyocyte allografts.
Tue Dec 01 00:00:00 EST 2020
Immunomodulatory activity of IR700-labelled affibody targeting HER2.
Cell death & disease
Mączyńska J,Da Pieve C,Burley TA,Raes F,Shah A,Saczko J,Harrington KJ,Kramer-Marek G
Tue Oct 20 00:00:00 EDT 2020
Specific Effects of Trabectedin and Lurbinectedin on Human Macrophage Function and Fate-Novel Insights.
Cancers
Povo-Retana A,Mojena M,Stremtan AB,Fernández-García VB,Gómez-Sáez A,Nuevo-Tapioles C,Molina-Guijarro JM,Avendaño-Ortiz J,Cuezva JM,López-Collazo E,Martínez-Leal JF,Boscá L
200-04 was used in In vitro experiments to study the effect of trabectedin and lurbinectedin on human macrophage cell viability and function.
Tue Oct 20 00:00:00 EDT 2020
Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage.
The Journal of biological chemistry
Jobin PG,Solis N,Machado Y,Bell PA,Rai SK,Kwon NH,Kim S,Overall CM,Butler GS
Fri Feb 21 00:00:00 EST 2020
Glycogen metabolism regulates macrophage-mediated acute inflammatory responses.
Nature communications
Ma J,Wei K,Liu J,Tang K,Zhang H,Zhu L,Chen J,Li F,Xu P,Chen J,Liu J,Fang H,Tang L,Wang D,Zeng L,Sun W,Xie J,Liu Y,Huang B
Tue Apr 14 00:00:00 EDT 2020
Chlorzoxazone, a small molecule drug, augments immunosuppressive capacity of mesenchymal stem cells via modulation of FOXO3 phosphorylation.
Cell death & disease
Deng L,Li H,Su X,Zhang Y,Xu H,Fan L,Fan J,Han Q,Bai X,Zhao RC
Mon Mar 02 00:00:00 EST 2020
Anti-ORAI1 antibody DS-2741a, a specific CRAC channel blocker, shows ideal therapeutic profiles for allergic disease via suppression of aberrant T-cell and mast cell activation.
FASEB bioAdvances
Aki A,Tanaka K,Nagaoka N,Kimura T,Baba D,Onodera Y,Wada T,Maeda H,Nakanishi T,Agatsuma T,Komai T
Sat Aug 01 00:00:00 EDT 2020
Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma.
Nature communications
Tao W,Chu C,Zhou W,Huang Z,Zhai K,Fang X,Huang Q,Zhang A,Wang X,Yu X,Huang H,Wu Q,Sloan AE,Yu JS,Li X,Stark GR,Rich JN,Bao S
Mon Jun 15 00:00:00 EDT 2020
Endogenous antisense RNA curbs CD39 expression in Crohn's disease.
Nature communications
Harshe RP,Xie A,Vuerich M,Frank LA,Gromova B,Zhang H,Robles RJ,Mukherjee S,Csizmadia E,Kokkotou E,Cheifetz AS,Moss AC,Kota SK,Robson SC,Longhi MS
Wed Nov 18 00:00:00 EST 2020
In vivo non-invasive staining-free visualization of dermal mast cells in healthy, allergy and mastocytosis humans using two-photon fluorescence lifetime imaging.
Scientific reports
Kröger M,Scheffel J,Nikolaev VV,Shirshin EA,Siebenhaar F,Schleusener J,Lademann J,Maurer M,Darvin ME
Thu Sep 10 00:00:00 EDT 2020
Alarmin-painted exosomes elicit persistent antitumor immunity in large established tumors in mice.
Nature communications
Zuo B,Qi H,Lu Z,Chen L,Sun B,Yang R,Zhang Y,Liu Z,Gao X,You A,Wu L,Jing R,Zhou Q,Yin H
Tue Apr 14 00:00:00 EDT 2020
Development and Preliminary Clinical Activity of PD-1-Guided CTLA-4 Blocking Bispecific DART Molecule.
Cell reports. Medicine
Berezhnoy A,Sumrow BJ,Stahl K,Shah K,Liu D,Li J,Hao SS,De Costa A,Kaul S,Bendell J,Cote GM,Luke JJ,Sanborn RE,Sharma MR,Chen F,Li H,Diedrich G,Bonvini E,Moore PA
200-04 was used in Cell Culture to conclude that MGD019 demonstrates encouraging activity in tumors traditionally unresponsive to checkpoint blockade.
Tue Dec 22 00:00:00 EST 2020
Autologous apoptotic neutrophils inhibit inflammatory cytokine secretion by human dendritic cells, but enhance Th1 responses.
FEBS open bio
Majai GE,Gogolák P,Tóth M,Hodrea J,Horváth D,Fésüs L,Rajnavölgyi É,Bácsi A
Sat Aug 01 00:00:00 EDT 2020
Staphylococcus aureus-Derived α-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution.
Cell reports
Jordan PM,Gerstmeier J,Pace S,Bilancia R,Rao Z,Börner F,Miek L,Gutiérrez-Gutiérrez Ó,Arakandy V,Rossi A,Ialenti A,González-Estévez C,Löffler B,Tuchscherr L,Serhan CN,Werz O
200-04 was used in In vitro experiments to investigate the role of α-hemolysin from Staphylococcus aureus in the activation of specialized pro-resolving mediators.
Tue Oct 13 00:00:00 EDT 2020
RPTPε promotes M2-polarized macrophage migration through ROCK2 signaling and podosome formation.
Journal of cell science
Lapointe F,Turcotte S,Roy J,Bissonnette E,Rola-Pleszczynski M,Stankova J
200-04 was used in Cell Culture to show that differentiation and polarization of monocytes into M2-polarized hMDMs modulates the expression of PTPε isoforms and RPTPε is involved in podosome distribution, ROCK2 activation and migration in response to LTD4.
Tue Jan 21 00:00:00 EST 2020
T Cell Receptor Engineered Lymphocytes for Cancer Therapy.
Current protocols in immunology
Rollins MR,Spartz EJ,Stromnes IM
200-04 was used in Cell Culture to synthesize and expand upon methodologies to generate, isolate, and engineer human T cells with tumor-reactive TCRs for adoptive cell therapy.
Mon Jun 01 00:00:00 EDT 2020
The regulatory role of PGC1α-related coactivator in response to drug-induced liver injury.
FASEB bioAdvances
Buler M,Naessens T,Mattsson J,Morias Y,Söderberg M,Robbins P,Kärrberg L,Svensson TS,Thulin P,Glinghammar B,Scarpulla RC,Andersson U
Sat Aug 01 00:00:00 EDT 2020
Triggering Receptor Expressed on Myeloid Cell 2 R47H Exacerbates Immune Response in Alzheimer's Disease Brain.
Frontiers in immunology
Korvatska O,Kiianitsa K,Ratushny A,Matsushita M,Beeman N,Chien WM,Satoh JI,Dorschner MO,Keene CD,Bammler TK,Bird TD,Raskind WH
200-04 was used in Cell Culture to point to a role of the TREM2 receptor in the control of the interferon type I response in myeloid cells and provide insight regarding the contribution of R47H TREM2 to AD pathology.
Fri Apr 30 00:00:00 EDT 2021
The transcription factor C/EBPβ orchestrates dendritic cell maturation and functionality under homeostatic and malignant conditions.
Proceedings of the National Academy of Sciences of the United States of America
Scholz F,Grau M,Menzel L,Graband A,Zapukhlyak M,Leutz A,Janz M,Lenz G,Rehm A,Höpken UE
Tue Oct 20 00:00:00 EDT 2020
Osteoclast-expanded super-charged NK-cells preferentially select and expand CD8+ T cells.
Scientific reports
Kaur K,Ko MW,Ohanian N,Cook J,Jewett A
Mon Nov 23 00:00:00 EST 2020
Autophagy deficiency promotes triple-negative breast cancer resistance to T cell-mediated cytotoxicity by blocking tenascin-C degradation.
Nature communications
Li ZL,Zhang HL,Huang Y,Huang JH,Sun P,Zhou NN,Chen YH,Mai J,Wang Y,Yu Y,Zhou LH,Li X,Yang D,Peng XD,Feng GK,Tang J,Zhu XF,Deng R
200-04 was used in In vitro experiments to provide a potential strategy for targeting triple-negative breast cancer with the combination of Tenascin-C blockade and immune checkpoint inhibitors.
Thu Jul 30 00:00:00 EDT 2020
CD40L membrane retention enhances the immunostimulatory effects of CD40 ligation.
Scientific reports
Elmetwali T,Salman A,Wei W,Hussain SA,Young LS,Palmer DH
Wed Jan 15 00:00:00 EST 2020
Intact B-Cell Signaling and Function With Host B-Cells 47 Years After Transplantation for X-SCID.
Frontiers in immunology
Deal C,Thauland TJ,Stiehm ER,Garcia-Lloret MI,Butte MJ
200-04 was used in Sample Preparation (FC/FACS) to demonstrate that satisfactory B-cell function can arise as a consequence of both intact IL-21 signaling due to a hypomorphic γc variant, and close HLA matching with the donor to allow for effective T-cell help.
Mon Mar 08 00:00:00 EST 2021
Immunogenic neoantigens derived from gene fusions stimulate T cell responses.
Nature medicine
Yang W,Lee KW,Srivastava RM,Kuo F,Krishna C,Chowell D,Makarov V,Hoen D,Dalin MG,Wexler L,Ghossein R,Katabi N,Nadeem Z,Cohen MA,Tian SK,Robine N,Arora K,Geiger H,Agius P,Bouvier N,Huberman K,Vanness K,Havel JJ,Sims JS,Samstein RM,Mandal R,Tepe J,Ganly I,Ho AL,Riaz N,Wong RJ,Shukla N,Chan TA,Morris LGT
200-04 was used in Cell Culture to study the gene fusions as a source of immunogenic neoantigens that can mediate responses to immunotherapy.
Wed May 01 00:00:00 EDT 2019
Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment.
Cell
Georgouli M,Herraiz C,Crosas-Molist E,Fanshawe B,Maiques O,Perdrix A,Pandya P,Rodriguez-Hernandez I,Ilieva KM,Cantelli G,Karagiannis P,Mele S,Lam H,Josephs DH,Matias-Guiu X,Marti RM,Nestle FO,Orgaz JL,Malanchi I,Fruhwirth GO,Karagiannis SN,Sanz-Moreno V
Thu Feb 07 00:00:00 EST 2019
Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism.
Cell
Watanabe A,McCarthy KR,Kuraoka M,Schmidt AG,Adachi Y,Onodera T,Tonouchi K,Caradonna TM,Bajic G,Song S,McGee CE,Sempowski GD,Feng F,Urick P,Kepler TB,Takahashi Y,Harrison SC,Kelsoe G
Thu May 16 00:00:00 EDT 2019
PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways.
Immunity
Zhao Y,Lee CK,Lin CH,Gassen RB,Xu X,Huang Z,Xiao C,Bonorino C,Lu LF,Bui JD,Hui E
Tue Dec 17 00:00:00 EST 2019
The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair.
Immunity
Kusnadi A,Park SH,Yuan R,Pannellini T,Giannopoulou E,Oliver D,Lu T,Park-Min KH,Ivashkiv LB
Tue Aug 20 00:00:00 EDT 2019
Single-Cell Survey of Human Lymphatics Unveils Marked Endothelial Cell Heterogeneity and Mechanisms of Homing for Neutrophils.
Immunity
Takeda A,Hollmén M,Dermadi D,Pan J,Brulois KF,Kaukonen R,Lönnberg T,Boström P,Koskivuo I,Irjala H,Miyasaka M,Salmi M,Butcher EC,Jalkanen S
Tue Sep 17 00:00:00 EDT 2019
Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology.
Immunity
Schwartz DM,Farley TK,Richoz N,Yao C,Shih HY,Petermann F,Zhang Y,Sun HW,Hayes E,Mikami Y,Jiang K,Davis FP,Kanno Y,Milner JD,Siegel R,Laurence A,Meylan F,O'Shea JJ
Tue Jan 15 00:00:00 EST 2019
Low-dose chidamide restores immune tolerance in ITP in mice and humans.
Blood
Zhao HY,Ma YH,Li DQ,Sun T,Li LZ,Li P,Liu XG,Zhou H,Hou Y,Liu Y,Han PP,Zhao YJ,Jing FM,Peng J,Hou M
Thu Feb 14 00:00:00 EST 2019
Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer.
Cell stem cell
Zhu Y,Smith DJ,Zhou Y,Li YR,Yu J,Lee D,Wang YC,Di Biase S,Wang X,Hardoy C,Ku J,Tsao T,Lin LJ,Pham AT,Moon H,McLaughlin J,Cheng D,Hollis RP,Campo-Fernandez B,Urbinati F,Wei L,Pang L,Rezek V,Berent-Maoz B,Macabali MH,Gjertson D,Wang X,Galic Z,Kitchen SG,An DS,Hu-Lieskovan S,Kaplan-Lefko PJ,De Oliveira SN,Seet CS,Larson SM,Forman SJ,Heath JR,Zack JA,Crooks GM,Radu CG,Ribas A,Kohn DB,Witte ON,Yang L
200-04 was used in Sample Preparation (FC/FACS) to develop a proof-of-concept for hematopoietic stem cell-engineered invariant natural killer T (iNKT) cell therapy with the potential to provide therapeutic levels of iNKT cells for a patient's lifetime.
Thu Oct 03 00:00:00 EDT 2019
Neoantigen identification strategies enable personalized immunotherapy in refractory solid tumors.
The Journal of clinical investigation
Chen F,Zou Z,Du J,Su S,Shao J,Meng F,Yang J,Xu Q,Ding N,Yang Y,Liu Q,Wang Q,Sun Z,Zhou S,Du S,Wei J,Liu B
Wed May 01 00:00:00 EDT 2019
Recognition of human gastrointestinal cancer neoantigens by circulating PD-1+ lymphocytes.
The Journal of clinical investigation
Gros A,Tran E,Parkhurst MR,Ilyas S,Pasetto A,Groh EM,Robbins PF,Yossef R,Garcia-Garijo A,Fajardo CA,Prickett TD,Jia L,Gartner JJ,Ray S,Ngo L,Wunderllich JR,Yang JC,Rosenberg SA
Fri Nov 01 00:00:00 EDT 2019
Repurposing rotavirus vaccines for intratumoral immunotherapy can overcome resistance to immune checkpoint blockade.
Science translational medicine
Shekarian T,Sivado E,Jallas AC,Depil S,Kielbassa J,Janoueix-Lerosey I,Hutter G,Goutagny N,Bergeron C,Viari A,Valsesia-Wittmann S,Caux C,Marabelle A
200-04 was used in Sample Preparation (FC/FACS) to study whether anti-infectious disease vaccines could be used as a commercially available source of immunostimulatory agents for cancer immunotherapy.
Wed Oct 23 00:00:00 EDT 2019
Regulatory roles of IL-10-producing human follicular T cells.
The Journal of experimental medicine
Cañete PF,Sweet RA,Gonzalez-Figueroa P,Papa I,Ohkura N,Bolton H,Roco JA,Cuenca M,Bassett KJ,Sayin I,Barry E,Lopez A,Canaday DH,Meyer-Hermann M,Doglioni C,Fazekas de St Groth B,Sakaguchi S,Cook MC,Vinuesa CG
Mon Aug 05 00:00:00 EDT 2019
Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR.
The Journal of experimental medicine
Deng M,Guo H,Tam JW,Johnson BM,Brickey WJ,New JS,Lenox A,Shi H,Golenbock DT,Koller BH,McKinnon KP,Beutler B,Ting JP
Mon Dec 02 00:00:00 EST 2019
Mycobacterium tuberculosis releases an antacid that remodels phagosomes.
Nature chemical biology
Buter J,Cheng TY,Ghanem M,Grootemaat AE,Raman S,Feng X,Plantijn AR,Ennis T,Wang J,Cotton RN,Layre E,Ramnarine AK,Mayfield JA,Young DC,Jezek Martinot A,Siddiqi N,Wakabayashi S,Botella H,Calderon R,Murray M,Ehrt S,Snider BB,Reed MB,Oldfield E,Tan S,Rubin EJ,Behr MA,van der Wel NN,Minnaard AJ,Moody DB
200-04 was used in Sample Preparation (FC/FACS) to study how Mycobacterium tuberculosis (Mtb)-produced 1-tuberculosinyladenosine (1-TbAd) is a naturally evolved phagolysosome disruptor.
Sun Sep 01 00:00:00 EDT 2019
Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells.
Proceedings of the National Academy of Sciences of the United States of America
Bedard M,Shrestha D,Priestman DA,Wang Y,Schneider F,Matute JD,Iyer SS,Gileadi U,Prota G,Kandasamy M,Veerapen N,Besra G,Fritzsche M,Zeissig S,Shevchenko A,Christianson JC,Platt FM,Eggeling C,Blumberg RS,Salio M,Cerundolo V
Tue Nov 19 00:00:00 EST 2019
Transcription factor networks in aged naïve CD4 T cells bias lineage differentiation.
Aging cell
Hu B,Li G,Ye Z,Gustafson CE,Tian L,Weyand CM,Goronzy JJ
Thu Aug 01 00:00:00 EDT 2019
M2 macrophages mediate sorafenib resistance by secreting HGF in a feed-forward manner in hepatocellular carcinoma.
British journal of cancer
Dong N,Shi X,Wang S,Gao Y,Kuang Z,Xie Q,Li Y,Deng H,Wu Y,Li M,Li JL
Mon Jul 01 00:00:00 EDT 2019
Tumour cell-derived debris and IgG synergistically promote metastasis of pancreatic cancer by inducing inflammation via tumour-associated macrophages.
British journal of cancer
Chen Q,Wang J,Zhang Q,Zhang J,Lou Y,Yang J,Chen Y,Wei T,Zhang J,Fu Q,Ye M,Zhang X,Dang X,Liang T,Bai X
Tue Oct 01 00:00:00 EDT 2019
ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism.
Mucosal immunology
Fang R,Uchiyama R,Sakai S,Hara H,Tsutsui H,Suda T,Mitsuyama M,Kawamura I,Tsuchiya K
Sun Sep 01 00:00:00 EDT 2019
Poly(I:C) stimulation is superior than Imiquimod to induce the antitumoral functional profile of tumor-conditioned macrophages.
European journal of immunology
Maeda A,Digifico E,Andon FT,Mantovani A,Allavena P
Wed May 01 00:00:00 EDT 2019
Soluble factors derived from neuroblastoma cell lines suppress dendritic cell differentiation and activation.
Cancer science
Harada K,Ihara F,Takami M,Kamata T,Mise N,Yoshizawa H,Hishiki T,Saito T,Terui K,Nakata M,Komatsu S,Ikeuchi T,Nakayama T,Yoshida H,Motohashi S
Fri Mar 01 00:00:00 EST 2019
Vascular endothelial growth factor (VEGF) impairs the motility and immune function of human mature dendritic cells through the VEGF receptor 2-RhoA-cofilin1 pathway.
Cancer science
Long J,Hu Z,Xue H,Wang Y,Chen J,Tang F,Zhou J,Liu L,Qiu W,Zhang S,Ouyang Y,Ye Y,Xu G,Li L,Zeng Z
Thu Aug 01 00:00:00 EDT 2019
dPGS Regulates the Phenotype of Macrophages via Metabolic Switching.
Macromolecular bioscience
Wu H,Reimann S,Siddiqui S,Haag R,Siegmund B,Dernedde J,Glauben R
Sun Dec 01 00:00:00 EST 2019
Citrullination Controls Dendritic Cell Transdifferentiation into Osteoclasts.
Journal of immunology (Baltimore, Md. : 1950)
Krishnamurthy A,Ytterberg AJ,Sun M,Sakuraba K,Steen J,Joshua V,Tarasova NK,Malmström V,Wähämaa H,Réthi B,Catrina AI
Sat Jun 01 00:00:00 EDT 2019
Exosomes Produced by Mesenchymal Stem Cells Drive Differentiation of Myeloid Cells into Immunosuppressive M2-Polarized Macrophages in Breast Cancer.
Journal of immunology (Baltimore, Md. : 1950)
Biswas S,Mandal G,Roy Chowdhury S,Purohit S,Payne KK,Anadon C,Gupta A,Swanson P,Yu X,Conejo-Garcia JR,Bhattacharyya A
Sun Dec 15 00:00:00 EST 2019
Identification of Neoantigen-Reactive Tumor-Infiltrating Lymphocytes in Primary Bladder Cancer.
Journal of immunology (Baltimore, Md. : 1950)
Leko V,McDuffie LA,Zheng Z,Gartner JJ,Prickett TD,Apolo AB,Agarwal PK,Rosenberg SA,Lu YC
Sat Jun 15 00:00:00 EDT 2019
Immune-Focusing Properties of Virus-like Particles Improve Protective IgA Responses.
Journal of immunology (Baltimore, Md. : 1950)
Onodera T,Hashi K,Shukla RK,Miki M,Takai-Todaka R,Fujimoto A,Kuraoka M,Miyoshi T,Kobayashi K,Hasegawa H,Ato M,Kelsoe G,Katayama K,Takahashi Y
Sun Dec 15 00:00:00 EST 2019
Synergy between B cell receptor/antigen uptake and MHCII peptide editing relies on HLA-DO tuning.
Scientific reports
Jiang W,Adler LN,Macmillan H,Mellins ED
Wed Sep 25 00:00:00 EDT 2019
Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn's disease.
Nature communications
Ziegler JF,Böttcher C,Letizia M,Yerinde C,Wu H,Freise I,Rodriguez-Sillke Y,Stoyanova AK,Kreis ME,Asbach P,Kunkel D,Priller J,Anagnostopoulos I,Kühl AA,Miehle K,Stumvoll M,Tran F,Fredrich B,Forster M,Franke A,Bojarski C,Glauben R,Löscher BS,Siegmund B,Weidinger C
Tue Dec 10 00:00:00 EST 2019
Second Case of HOIP Deficiency Expands Clinical Features and Defines Inflammatory Transcriptome Regulated by LUBAC.
Frontiers in immunology
Oda H,Beck DB,Kuehn HS,Sampaio Moura N,Hoffmann P,Ibarra M,Stoddard J,Tsai WL,Gutierrez-Cruz G,Gadina M,Rosenzweig SD,Kastner DL,Notarangelo LD,Aksentijevich I
200-04 was used in In vitro experiments to identify a genetic cause of a disease for an 8 year-old girl who presented with early-onset immune deficiency and autoinflammation.
Thu Sep 10 00:00:00 EDT 2020
Src family kinase activity drives cytomegalovirus reactivation by recruiting MOZ histone acetyltransferase activity to the viral promoter.
The Journal of biological chemistry
Dupont L,Du L,Poulter M,Choi S,McIntosh M,Reeves MB
Fri Aug 30 00:00:00 EDT 2019
The citrus flavonoid naringenin impairs the in vitro infection of human cells by Zika virus.
Scientific reports
Cataneo AHD,Kuczera D,Koishi AC,Zanluca C,Silveira GF,Arruda TB,Suzukawa AA,Bortot LO,Dias-Baruffi M,Verri WA,Robert AW,Stimamiglio MA,Duarte Dos Santos CN,Wowk PF,Bordignon J
Fri Nov 08 00:00:00 EST 2019
A juxtacrine/paracrine loop between C-Kit and stem cell factor promotes cancer stem cell survival in epithelial ovarian cancer.
Cell death & disease
Mazzoldi EL,Pavan S,Pilotto G,Leone K,Pagotto A,Frezzini S,Nicoletto MO,Amadori A,Pastò A
Tue May 28 00:00:00 EDT 2019
Engineering of anti-human interleukin-4 receptor alpha antibodies with potent antagonistic activity.
Scientific reports
Kim JE,Jung K,Kim JA,Kim SH,Park HS,Kim YS
Thu May 23 00:00:00 EDT 2019
In-Depth Characterization of Monocyte-Derived Macrophages using a Mass Cytometry-Based Phagocytosis Assay.
Scientific reports
Schulz D,Severin Y,Zanotelli VRT,Bodenmiller B
Wed Feb 13 00:00:00 EST 2019
Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase.
The Journal of biological chemistry
Jobin PG,Solis N,Machado Y,Bell PA,Kwon NH,Kim S,Overall CM,Butler GS
Fri Aug 30 00:00:00 EDT 2019
The P-selectin and PSGL-1 axis accelerates atherosclerosis via activation of dendritic cells by the TLR4 signaling pathway.
Cell death & disease
Ye Z,Zhong L,Zhu S,Wang Y,Zheng J,Wang S,Zhang J,Huang R
Mon Jul 01 00:00:00 EDT 2019
Small extracellular vesicles containing arginase-1 suppress T-cell responses and promote tumor growth in ovarian carcinoma.
Nature communications
Czystowska-Kuzmicz M,Sosnowska A,Nowis D,Ramji K,Szajnik M,Chlebowska-Tuz J,Wolinska E,Gaj P,Grazul M,Pilch Z,Zerrouqi A,Graczyk-Jarzynka A,Soroczynska K,Cierniak S,Koktysz R,Elishaev E,Gruca S,Stefanowicz A,Blaszczyk R,Borek B,Gzik A,Whiteside T,Golab J
Fri Jul 05 00:00:00 EDT 2019
Exposure of an occluded hemagglutinin epitope drives selection of a class of cross-protective influenza antibodies.
Nature communications
Adachi Y,Tonouchi K,Nithichanon A,Kuraoka M,Watanabe A,Shinnakasu R,Asanuma H,Ainai A,Ohmi Y,Yamamoto T,Ishii KJ,Hasegawa H,Takeyama H,Lertmemongkolchai G,Kurosaki T,Ato M,Kelsoe G,Takahashi Y
Wed Aug 28 00:00:00 EDT 2019
Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation.
Frontiers in immunology
Lara-Reyna S,Scambler T,Holbrook J,Wong C,Jarosz-Griffiths HH,Martinon F,Savic S,Peckham D,McDermott MF
200-04 was used in Cell Culture to investigate signalling pathways following cystic fibrosis transmembrane conductance regulator mutations.
Tue Oct 13 00:00:00 EDT 2020
Transforming growth factor β1 alters the 3'-UTR of mRNA to promote lung fibrosis.
The Journal of biological chemistry
Ko J,Mills T,Huang J,Chen NY,Mertens TCJ,Collum SD,Lee G,Xiang Y,Han L,Zhou Y,Lee CG,Elias JA,Jyothula SSK,Rajagopal K,Karmouty-Quintana H,Blackburn MR
Fri Oct 25 00:00:00 EDT 2019
Erythromycin suppresses neutrophil extracellular traps in smoking-related chronic pulmonary inflammation.
Cell death & disease
Zhang H,Qiu SL,Tang QY,Zhou X,Zhang JQ,He ZY,Bai J,Li MH,Deng JM,Liang Y,Zhong XN
Thu Sep 12 00:00:00 EDT 2019
iRGD synergizes with PD-1 knockout immunotherapy by enhancing lymphocyte infiltration in gastric cancer.
Nature communications
Ding N,Zou Z,Sha H,Su S,Qian H,Meng F,Chen F,Du S,Zhou S,Chen H,Zhang L,Yang J,Wei J,Liu B
Fri Mar 22 00:00:00 EDT 2019
Non-thermal plasma inhibits mast cell activation and ameliorates allergic skin inflammatory diseases in NC/Nga mice.
Scientific reports
Lee MH,Lee YS,Kim HJ,Han CH,Kang SU,Kim CH
Wed Sep 18 00:00:00 EDT 2019
A tissue-like platform for studying engineered quiescent human T-cells' interactions with dendritic cells.
eLife
Abu-Shah E,Demetriou P,Bálint Š,Mayya V,Kutuzov MA,Dushek O,Dustin ML
200-04 was used in Cell Culture to report a tissue-like system that recapitulates the dynamics of engineered primary human immune cell and characterise unique dynamics of T-cell/DC interactions as a function of antigen affinity.
Wed Sep 25 00:00:00 EDT 2019
Myeloid Tribbles 1 induces early atherosclerosis via enhanced foam cell expansion.
Science advances
Johnston JM,Angyal A,Bauer RC,Hamby S,Suvarna SK,Baidžajevas K,Hegedus Z,Dear TN,Turner M,Wilson HL,Goodall AH,Rader DJ,Shoulders CC,Francis SE,Kiss-Toth E
200-04 was used in Cell Culture to suggest that a conserved, TRIB1-mediated mechanism drives foam cell formation in atherosclerotic plaque and that inhibiting mTRIB1 could be used therapeutically to reduce CHD.
Tue Oct 01 00:00:00 EDT 2019
ADP secreted by dying melanoma cells mediates chemotaxis and chemokine secretion of macrophages via the purinergic receptor P2Y12.
Cell death & disease
Kloss L,Dollt C,Schledzewski K,Krewer A,Melchers S,Manta C,Sticht C,Torre C,Utikal J,Umansky V,Schmieder A
Mon Oct 07 00:00:00 EDT 2019
Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients.
Nature communications
Cafri G,Yossef R,Pasetto A,Deniger DC,Lu YC,Parkhurst M,Gartner JJ,Jia L,Ray S,Ngo LT,Jafferji M,Sachs A,Prickett T,Robbins PF,Rosenberg SA
Fri Jan 25 00:00:00 EST 2019
LncRNA RPPH1 promotes colorectal cancer metastasis by interacting with TUBB3 and by promoting exosomes-mediated macrophage M2 polarization.
Cell death & disease
Liang ZX,Liu HS,Wang FW,Xiong L,Zhou C,Hu T,He XW,Wu XJ,Xie D,Wu XR,Lan P
Mon Nov 04 00:00:00 EST 2019
Senescence-associated reprogramming promotes cancer stemness.
Nature
Milanovic M,Fan DNY,Belenki D,Däbritz JHM,Zhao Z,Yu Y,Dörr JR,Dimitrova L,Lenze D,Monteiro Barbosa IA,Mendoza-Parra MA,Kanashova T,Metzner M,Pardon K,Reimann M,Trumpp A,Dörken B,Zuber J,Gronemeyer H,Hummel M,Dittmar G,Lee S,Schmitt CA
Thu Jan 04 00:00:00 EST 2018
Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages.
Cell
Su S,Zhao J,Xing Y,Zhang X,Liu J,Ouyang Q,Chen J,Su F,Liu Q,Song E
Thu Oct 04 00:00:00 EDT 2018
Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia.
Cell
Kim MY,Yu KR,Kenderian SS,Ruella M,Chen S,Shin TH,Aljanahi AA,Schreeder D,Klichinsky M,Shestova O,Kozlowski MS,Cummins KD,Shan X,Shestov M,Bagg A,Morrissette JJD,Sekhri P,Lazzarotto CR,Calvo KR,Kuhns DB,Donahue RE,Behbehani GK,Tsai SQ,Dunbar CE,Gill S
Thu May 31 00:00:00 EDT 2018
Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires.
Immunity
McCarthy KR,Watanabe A,Kuraoka M,Do KT,McGee CE,Sempowski GD,Kepler TB,Schmidt AG,Kelsoe G,Harrison SC
Tue Jan 16 00:00:00 EST 2018
Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection.
Cell host & microbe
Johnson JS,Lucas SY,Amon LM,Skelton S,Nazitto R,Carbonetti S,Sather DN,Littman DR,Aderem A
200-04 was used in Cell Culture to study how dendritic cells (DCs) detect HIV-1 in distinct phases, before and after virus integration in response to reverse transcription.
Wed Mar 14 00:00:00 EDT 2018
Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease.
The Journal of clinical investigation
Mao L,Kitani A,Similuk M,Oler AJ,Albenberg L,Kelsen J,Aktay A,Quezado M,Yao M,Montgomery-Recht K,Fuss IJ,Strober W
Tue May 01 00:00:00 EDT 2018
MicroRNA-210 overexpression promotes psoriasis-like inflammation by inducing Th1 and Th17 cell differentiation.
The Journal of clinical investigation
Wu R,Zeng J,Yuan J,Deng X,Huang Y,Chen L,Zhang P,Feng H,Liu Z,Wang Z,Gao X,Wu H,Wang H,Su Y,Zhao M,Lu Q
Fri Jun 01 00:00:00 EDT 2018
MicroRNA-210 overexpression promotes psoriasis-like inflammation by inducing Th1 and Th17 cell differentiation.
The Journal of clinical investigation
Wu R,Zeng J,Yuan J,Deng X,Huang Y,Chen L,Zhang P,Feng H,Liu Z,Wang Z,Gao X,Wu H,Wang H,Su Y,Zhao M,Lu Q
Fri Jun 01 00:00:00 EDT 2018
Spatial distribution and function of T follicular regulatory cells in human lymph nodes.
The Journal of experimental medicine
Sayin I,Radtke AJ,Vella LA,Jin W,Wherry EJ,Buggert M,Betts MR,Herati RS,Germain RN,Canaday DH
Mon Jun 04 00:00:00 EDT 2018
Mechanistic Insights of an Immunological Adverse Event Induced by an Anti-KIT Antibody Drug Conjugate and Mitigation Strategies.
Clinical cancer research : an official journal of the American Association for Cancer Research
L'Italien L,Orozco O,Abrams T,Cantagallo L,Connor A,Desai J,Ebersbach H,Gelderblom H,Hoffmaster K,Lees E,Maacke H,Schleyer S,Skegro D,Lee-Hoeflich ST
200-04 was used in In vitro experiments to identifying potential mitigation strategies in hypersensitivity reactions.
Sun Jul 15 00:00:00 EDT 2018
Functional muscle recovery with nanoparticle-directed M2 macrophage polarization in mice.
Proceedings of the National Academy of Sciences of the United States of America
Raimondo TM,Mooney DJ
Tue Oct 16 00:00:00 EDT 2018
Functional muscle recovery with nanoparticle-directed M2 macrophage polarization in mice.
Proceedings of the National Academy of Sciences of the United States of America
Raimondo TM,Mooney DJ
Tue Oct 16 00:00:00 EDT 2018
Interleukin 4 is inactivated via selective disulfide-bond reduction by extracellular thioredoxin.
Proceedings of the National Academy of Sciences of the United States of America
Plugis NM,Weng N,Zhao Q,Palanski BA,Maecker HT,Habtezion A,Khosla C
Tue Aug 28 00:00:00 EDT 2018
Interleukin 4 is inactivated via selective disulfide-bond reduction by extracellular thioredoxin.
Proceedings of the National Academy of Sciences of the United States of America
Plugis NM,Weng N,Zhao Q,Palanski BA,Maecker HT,Habtezion A,Khosla C
Tue Aug 28 00:00:00 EDT 2018
Targeting LAG-3 and PD-1 to Enhance T Cell Activation by Antigen-Presenting Cells.
Frontiers in immunology
Lichtenegger FS,Rothe M,Schnorfeil FM,Deiser K,Krupka C,Augsberger C,Schlüter M,Neitz J,Subklewe M
200-04 was used in In vitro experiments to compare the efficacy of dendritic cell receptor-ligand blockades at various immune checkpoints on T cell activation, an suggest targets for enhanced immunotherapy.
Mon Apr 08 00:00:00 EDT 2019
Lymphatic exosomes promote dendritic cell migration along guidance cues.
The Journal of cell biology
Brown M,Johnson LA,Leone DA,Majek P,Vaahtomeri K,Senfter D,Bukosza N,Schachner H,Asfour G,Langer B,Hauschild R,Parapatics K,Hong YK,Bennett KL,Kain R,Detmar M,Sixt M,Jackson DG,Kerjaschki D
Mon Jun 04 00:00:00 EDT 2018
Infection with flaviviruses requires BCLXL for cell survival.
PLoS pathogens
Suzuki T,Okamoto T,Katoh H,Sugiyama Y,Kusakabe S,Tokunaga M,Hirano J,Miyata Y,Fukuhara T,Ikawa M,Satoh T,Yoshio S,Suzuki R,Saijo M,Huang DCS,Kanto T,Akira S,Matsuura Y
200-04 was used in In vitro experiments to suggest that BCLXL plays a crucial role in the survival of cells infected with flaviviruses, and that BCLXL may provide a novel antiviral target to suppress propagation of the family of Flaviviridae viruses.
Sat Sep 01 00:00:00 EDT 2018
Increased infiltration of macrophages to radioresistant lung cancer cells contributes to the development of the additional resistance of tumor cells to the cytotoxic effects of NK cells.
International journal of oncology
Shen M,Chen Y,Xu L,Zhu R,Xue X,Tsai Y,Keng PC,Lee SO,Chen Y
200-04 was used in Cell Culture to suggest the existence of a malignant loop characterized by increased macrophage infiltration into radioresistant lung cancer cells which, in turn, promotes the development of the additional resistance of these cells to NK cell cytotoxicity.
Sun Jul 01 00:00:00 EDT 2018
Differentiation of Langerhans Cells from Monocytes and Their Specific Function in Inducing IL-22-Specific Th Cells.
Journal of immunology (Baltimore, Md. : 1950)
Otsuka Y,Watanabe E,Shinya E,Okura S,Saeki H,Geijtenbeek TBH,Takahashi H
Thu Nov 15 00:00:00 EST 2018
Toll-like Receptor 4-Induced Glycolytic Burst in Human Monocyte-Derived Dendritic Cells Results from p38-Dependent Stabilization of HIF-1α and Increased Hexokinase II Expression.
Journal of immunology (Baltimore, Md. : 1950)
Perrin-Cocon L,Aublin-Gex A,Diaz O,Ramière C,Peri F,André P,Lotteau V
Sat Sep 01 00:00:00 EDT 2018
Epitope-Binding Characteristics for Risk versus Protective DRB1 Alleles for Visceral Leishmaniasis.
Journal of immunology (Baltimore, Md. : 1950)
Singh T,Fakiola M,Oommen J,Singh AP,Singh AK,Smith N,Chakravarty J,Sundar S,Blackwell JM
Sun Apr 15 00:00:00 EDT 2018
Rapid and Efficient Production of Human Functional Mast Cells through a Three-Dimensional Culture of Adipose Tissue-Derived Stromal Vascular Cells.
Journal of immunology (Baltimore, Md. : 1950)
Paupert J,Espinosa E,Cenac N,Robert V,Laharrague P,Evrard SM,Casteilla L,Lorsignol A,Cousin B
Sat Dec 15 00:00:00 EST 2018
Apoptotic Cancer Cells Suppress 5-Lipoxygenase in Tumor-Associated Macrophages.
Journal of immunology (Baltimore, Md. : 1950)
Ringleb J,Strack E,Angioni C,Geisslinger G,Steinhilber D,Weigert A,Brüne B
Mon Jan 15 00:00:00 EST 2018
Golgi Phosphoprotein 2 Is a Novel Regulator of IL-12 Production and Macrophage Polarization.
Journal of immunology (Baltimore, Md. : 1950)
Zhang W,Kim H,Lv J,Zhao N,Ma X
Thu Feb 15 00:00:00 EST 2018
BMP-2 induces human mononuclear cell chemotaxis and adhesion and modulates monocyte-to-macrophage differentiation.
Journal of cellular and molecular medicine
Pardali E,Makowski LM,Leffers M,Borgscheiper A,Waltenberger J
Thu Nov 01 00:00:00 EDT 2018
GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation.
Nature communications
Offenbacher S,Jiao Y,Kim SJ,Marchesan J,Moss KL,Jing L,Divaris K,Bencharit S,Agler CS,Morelli T,Zhang S,Sun L,Seaman WT,Cowley D,Barros SP,Beck JD,Munz M,Schaefer AS,North KE
Tue Sep 11 00:00:00 EDT 2018
Kyasanur Forest disease virus infection activates human vascular endothelial cells and monocyte-derived dendritic cells.
Emerging microbes & infections
Sirmarova J,Salat J,Palus M,Hönig V,Langhansova H,Holbrook MR,Ruzek D
Wed Nov 07 00:00:00 EST 2018
Aluminum fluoride-18 labeled folate enables in vivo detection of atherosclerotic plaque inflammation by positron emission tomography.
Scientific reports
Silvola JMU,Li XG,Virta J,Marjamäki P,Liljenbäck H,Hytönen JP,Tarkia M,Saunavaara V,Hurme S,Palani S,Hakovirta H,Ylä-Herttuala S,Saukko P,Chen Q,Low PS,Knuuti J,Saraste A,Roivainen A
Tue Jun 26 00:00:00 EDT 2018
Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets.
Nature communications
Aulicino A,Rue-Albrecht KC,Preciado-Llanes L,Napolitani G,Ashley N,Cribbs A,Koth J,Lagerholm BC,Ambrose T,Gordon MA,Sims D,Simmons A
Mon Nov 19 00:00:00 EST 2018
CXCL1 derived from tumor-associated macrophages promotes breast cancer metastasis via activating NF-κB/SOX4 signaling.
Cell death & disease
Wang N,Liu W,Zheng Y,Wang S,Yang B,Li M,Song J,Zhang F,Zhang X,Wang Q,Wang Z
Wed Aug 29 00:00:00 EDT 2018
CXCL1 derived from tumor-associated macrophages promotes breast cancer metastasis via activating NF-κB/SOX4 signaling.
Cell death & disease
Wang N,Liu W,Zheng Y,Wang S,Yang B,Li M,Song J,Zhang F,Zhang X,Wang Q,Wang Z
Wed Aug 29 00:00:00 EDT 2018
A conserved enhancer regulates Il9 expression in multiple lineages.
Nature communications
Koh B,Abdul Qayum A,Srivastava R,Fu Y,Ulrich BJ,Janga SC,Kaplan MH
Thu Nov 15 00:00:00 EST 2018
IFNα Impairs Autophagic Degradation of mtDNA Promoting Autoreactivity of SLE Monocytes in a STING-Dependent Fashion.
Cell reports
Gkirtzimanaki K,Kabrani E,Nikoleri D,Polyzos A,Blanas A,Sidiropoulos P,Makrigiannakis A,Bertsias G,Boumpas DT,Verginis P
200-04 was used in Cell Culture to demonstrate IFNα-mediated deregulation of mitochondrial metabolism and impairment of autophagic degradation, leading to cytosolic accumulation of mtDNA that is sensed via stimulator of interferon genes (STING) to promote induction of autoinflammatory DCs.
Tue Oct 23 00:00:00 EDT 2018
A malaria protein factor induces IL-4 production by dendritic cells via PI3K-Akt-NF-κB signaling independent of MyD88/TRIF and promotes Th2 response.
The Journal of biological chemistry
Wu X,Gowda NM,Kawasawa YI,Gowda DC
Fri Jul 06 00:00:00 EDT 2018
Analysis of the Trichuris suis excretory/secretory proteins as a function of life cycle stage and their immunomodulatory properties.
Scientific reports
Leroux LP,Nasr M,Valanparambil R,Tam M,Rosa BA,Siciliani E,Hill DE,Zarlenga DS,Jaramillo M,Weinstock JV,Geary TG,Stevenson MM,Urban JF,Mitreva M,Jardim A
Mon Oct 29 00:00:00 EDT 2018
Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function.
Nature communications
Laustsen A,Bak RO,Krapp C,Kjær L,Egedahl JH,Petersen CC,Pillai S,Tang HQ,Uldbjerg N,Porteus M,Roan NR,Nyegaard M,Denton PW,Jakobsen MR
Thu Aug 30 00:00:00 EDT 2018
USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy.
Nature communications
Wang YC,Wu YS,Hung CY,Wang SA,Young MJ,Hsu TI,Hung JJ
Fri Sep 28 00:00:00 EDT 2018
Stromal C-type lectin receptor COLEC12 integrates H. pylori, PGE2-EP2/4 axis and innate immunity in gastric diseases.
Scientific reports
Chang LL,Hsu WH,Kao MC,Chou CC,Lin CC,Liu CJ,Weng BC,Kuo FC,Kuo CH,Lin MH,Wang CJ,Lin CH,Wu DC,Huang SK
Wed Feb 28 00:00:00 EST 2018
Compromised functionality of monocyte-derived dendritic cells in multiple myeloma patients may limit their use in cancer immunotherapy.
Scientific reports
Shinde P,Fernandes S,Melinkeri S,Kale V,Limaye L
Mon Apr 09 00:00:00 EDT 2018
Human Sox4 facilitates the development of CXCL13-producing helper T cells in inflammatory environments.
Nature communications
Yoshitomi H,Kobayashi S,Miyagawa-Hayashino A,Okahata A,Doi K,Nishitani K,Murata K,Ito H,Tsuruyama T,Haga H,Matsuda S,Toguchida J
Wed Sep 19 00:00:00 EDT 2018
The novel immunoglobulin super family receptor SLAMF9 identified in TAM of murine and human melanoma influences pro-inflammatory cytokine secretion and migration.
Cell death & disease
Dollt C,Michel J,Kloss L,Melchers S,Schledzewski K,Becker K,Sauer A,Krewer A,Koll F,Schmieder A
Wed Sep 19 00:00:00 EDT 2018
C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease.
Nature communications
Dufour A,Bellac CL,Eckhard U,Solis N,Klein T,Kappelhoff R,Fortelny N,Jobin P,Rozmus J,Mark J,Pavlidis P,Dive V,Barbour SJ,Overall CM
Wed Jun 20 00:00:00 EDT 2018
The oligosaccharides 6'-sialyllactose, 2'-fucosyllactose or galactooligosaccharides do not directly modulate human dendritic cell differentiation or maturation.
PloS one
Perdijk O,van Neerven RJJ,van den Brink E,Savelkoul HFJ,Brugman S
200-04 was used in Cell Culture to study the effect of human milk oligosaccharides (HMOs) 6'-sialyllactose (6'SL) and 2'-fucosyllactose (2'FL) as well as prebiotic galactooligosaccharides (GOS) on dendritic cell (DC) differentiation and maturation to study how HMOs contribute to immune homeostasis and protection against disease.
Tue Jan 22 00:00:00 EST 2019
Neutrophil Microvesicles from Healthy Control and Rheumatoid Arthritis Patients Prevent the Inflammatory Activation of Macrophages.
EBioMedicine
Rhys HI,Dell'Accio F,Pitzalis C,Moore A,Norling LV,Perretti M
200-04 was used in In vitro experiments to present new mechanistic evidence underpinning the anti-inflammatory and anti-arthritic properties of neutrophil microvesicles.
Thu Mar 01 00:00:00 EST 2018
A novel probe to assess cytosolic entry of exogenous proteins.
Nature communications
Lu Q,Grotzke JE,Cresswell P
Mon Aug 06 00:00:00 EDT 2018
Integrin CD11b activation drives anti-tumor innate immunity.
Nature communications
Schmid MC,Khan SQ,Kaneda MM,Pathria P,Shepard R,Louis TL,Anand S,Woo G,Leem C,Faridi MH,Geraghty T,Rajagopalan A,Gupta S,Ahmed M,Vazquez-Padron RI,Cheresh DA,Gupta V,Varner JA
Wed Dec 19 00:00:00 EST 2018
Integrin CD11b activation drives anti-tumor innate immunity.
Nature communications
Schmid MC,Khan SQ,Kaneda MM,Pathria P,Shepard R,Louis TL,Anand S,Woo G,Leem C,Faridi MH,Geraghty T,Rajagopalan A,Gupta S,Ahmed M,Vazquez-Padron RI,Cheresh DA,Gupta V,Varner JA
Wed Dec 19 00:00:00 EST 2018
IL-1β- and IL-4-polarized macrophages have opposite effects on adipogenesis of intramuscular fibro-adipogenic progenitors in humans.
Scientific reports
Moratal C,Raffort J,Arrighi N,Rekima S,Schaub S,Dechesne CA,Chinetti G,Dani C
Mon Nov 19 00:00:00 EST 2018
A Renewable Source of Human Beige Adipocytes for Development of Therapies to Treat Metabolic Syndrome.
Cell reports
Su S,Guntur AR,Nguyen DC,Fakory SS,Doucette CC,Leech C,Lotana H,Kelley M,Kohli J,Martino J,Sims-Lucas S,Liaw L,Vary C,Rosen CJ,Brown AC
200-04 was used in In vitro experiments to develop a robust method to generate a renewable source of human beige adipocytes from induced pluripotent stem cells (iPSCs).
Tue Dec 11 00:00:00 EST 2018
Polarization of Human Macrophages by Interleukin-4 Does Not Require ATP-Citrate Lyase.
Frontiers in immunology
Namgaladze D,Zukunft S,Schnütgen F,Kurrle N,Fleming I,Fuhrmann D,Brüne B
200-04 was used in Cell Culture to suggest that ACLY may not be the major regulator of nucleocytoplasmic acetyl-CoA and IL-4-induced polarization in human macrophages.
Fri Oct 25 00:00:00 EDT 2019
M2 macrophage-mediated interleukin-4 signalling induces myofibroblast phenotype during the progression of benign prostatic hyperplasia.
Cell death & disease
Sheng J,Yang Y,Cui Y,He S,Wang L,Liu L,He Q,Lv T,Han W,Yu W,Hu S,Jin J
Mon Jul 09 00:00:00 EDT 2018
March1-dependent modulation of donor MHC II on CD103+ dendritic cells mitigates alloimmunity.
Nature communications
Borges TJ,Murakami N,Machado FD,Murshid A,Lang BJ,Lopes RL,Bellan LM,Uehara M,Antunes KH,Pérez-Saéz MJ,Birrane G,Vianna P,Gonçalves JIB,Zanin RF,Azzi J,Abdi R,Ishido S,Shin JS,Souza APD,Calderwood SK,Riella LV,Bonorino C
Tue Aug 28 00:00:00 EDT 2018
Regulation of IL-22BP in psoriasis.
Scientific reports
Voglis S,Moos S,Kloos L,Wanke F,Zayoud M,Pelczar P,Giannou AD,Pezer S,Albers M,Luessi F,Huber S,Schäkel K,Kurschus FC
Fri Mar 23 00:00:00 EDT 2018
Birth mode is associated with earliest strain-conferred gut microbiome functions and immunostimulatory potential.
Nature communications
Wampach L,Heintz-Buschart A,Fritz JV,Ramiro-Garcia J,Habier J,Herold M,Narayanasamy S,Kaysen A,Hogan AH,Bindl L,Bottu J,Halder R,Sjöqvist C,May P,Andersson AF,de Beaufort C,Wilmes P
Fri Nov 30 00:00:00 EST 2018
Regulatory NLRs Control the RLR-Mediated Type I Interferon and Inflammatory Responses in Human Dendritic Cells.
Frontiers in immunology
Fekete T,Bencze D,Szabo A,Csoma E,Biro T,Bacsi A,Pazmandi K
200-04 was used in Cell Culture to exhibit that NLRX1 is the primary regulator of RLR-mediated innate immune response in human dendritic cells, while NLRC5s only hold a supplemntary role.
Thu Oct 03 00:00:00 EDT 2019
Macrophage-secreted interleukin-35 regulates cancer cell plasticity to facilitate metastatic colonization.
Nature communications
Lee CC,Lin JC,Hwang WL,Kuo YJ,Chen HK,Tai SK,Lin CC,Yang MH
Fri Sep 14 00:00:00 EDT 2018
A Pilot Study To Investigate the Immune-Modulatory Effects of Fasting in Steroid-Naive Mild Asthmatics.
Journal of immunology (Baltimore, Md. : 1950)
Han K,Nguyen A,Traba J,Yao X,Kaler M,Huffstutler RD,Levine SJ,Sack MN
Sat Sep 01 00:00:00 EDT 2018
PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis.
Nature
Wartewig T,Kurgyis Z,Keppler S,Pechloff K,Hameister E,Öllinger R,Maresch R,Buch T,Steiger K,Winter C,Rad R,Ruland J
200-04 was used in In vitro experiments to evaluate the role of the receptor, Programmed Death 1, in T cell lymphomagenesis, and the potential implications of this in lymphoma therapy.
Thu Dec 07 00:00:00 EST 2017
High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization.
Immunity
Alcántara-Hernández M,Leylek R,Wagar LE,Engleman EG,Keler T,Marinkovich MP,Davis MM,Nolan GP,Idoyaga J
Tue Dec 19 00:00:00 EST 2017
Cell-Intrinsic Glycogen Metabolism Supports Early Glycolytic Reprogramming Required for Dendritic Cell Immune Responses.
Cell metabolism
Thwe PM,Pelgrom LR,Cooper R,Beauchamp S,Reisz JA,D'Alessandro A,Everts B,Amiel E
200-04 was used in In vitro experiments to study the contributions of intracellular glucose stores to glucose sourcing for the support of dendritic cell activation.
Tue Sep 05 00:00:00 EDT 2017
Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia.
Blood
Serafin V,Capuzzo G,Milani G,Minuzzo SA,Pinazza M,Bortolozzi R,Bresolin S,Porcù E,Frasson C,Indraccolo S,Basso G,Accordi B
Thu Dec 21 00:00:00 EST 2017
A noncanonical function of cGAMP in inflammasome priming and activation.
The Journal of experimental medicine
Swanson KV,Junkins RD,Kurkjian CJ,Holley-Guthrie E,Pendse AA,El Morabiti R,Petrucelli A,Barber GN,Benedict CA,Ting JP
Mon Dec 04 00:00:00 EST 2017
Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells.
Nature chemical biology
Johannessen L,Sundberg TB,O'Connell DJ,Kolde R,Berstler J,Billings KJ,Khor B,Seashore-Ludlow B,Fassl A,Russell CN,Latorre IJ,Jiang B,Graham DB,Perez JR,Sicinski P,Phillips AJ,Schreiber SL,Gray NS,Shamji AF,Xavier RJ
200-04 was used in Cell Culture to identify a function for CDK8 and CDK19 in regulating innate immune activation and suggest that these kinases may warrant consideration as therapeutic targets for inflammatory disorders.
Sun Oct 01 00:00:00 EDT 2017
Environment Tunes Propagation of Cell-to-Cell Variation in the Human Macrophage Gene Network.
Cell systems
Martins AJ,Narayanan M,Prüstel T,Fixsen B,Park K,Gottschalk RA,Lu Y,Andrews-Pfannkoch C,Lau WW,Wendelsdorf KV,Tsang JS
200-04 was used in In vitro experiments to explore context-dependent noise propagation among genes in human macrophages.
Wed Apr 26 00:00:00 EDT 2017
The Effect of Inhibitory Signals on the Priming of Drug Hapten-Specific T Cells That Express Distinct Vβ Receptors.
Journal of immunology (Baltimore, Md. : 1950)
Gibson A,Faulkner L,Lichtenfels M,Ogese M,Al-Attar Z,Alfirevic A,Esser PR,Martin SF,Pirmohamed M,Park BK,Naisbitt DJ
Tue Aug 15 00:00:00 EDT 2017
Activation of Human Mucosal-Associated Invariant T Cells Induces CD40L-Dependent Maturation of Monocyte-Derived and Primary Dendritic Cells.
Journal of immunology (Baltimore, Md. : 1950)
Salio M,Gasser O,Gonzalez-Lopez C,Martens A,Veerapen N,Gileadi U,Verter JG,Napolitani G,Anderson R,Painter G,Besra GS,Hermans IF,Cerundolo V
Sun Oct 15 00:00:00 EDT 2017
Efficiency and Safety of CRAC Inhibitors in Human Rheumatoid Arthritis Xenograft Models.
Journal of immunology (Baltimore, Md. : 1950)
Liu S,Hasegawa H,Takemasa E,Suzuki Y,Oka K,Kiyoi T,Takeda H,Ogasawara T,Sawasaki T,Yasukawa M,Maeyama K
Fri Sep 01 00:00:00 EDT 2017
Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages.
Journal of immunology (Baltimore, Md. : 1950)
Bellora F,Dondero A,Corrias MV,Casu B,Regis S,Caliendo F,Moretta A,Cazzola M,Elena C,Vinti L,Locatelli F,Bottino C,Castriconi R
Tue Aug 15 00:00:00 EDT 2017
Alternatively activated macrophages derived from THP-1 cells promote the fibrogenic activities of human dermal fibroblasts.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Zhu Z,Ding J,Ma Z,Iwashina T,Tredget EE
200-04 was used in In vitro experiments to show differentiation of M0 and polarization of M1 and M2 macrophages.
Mon May 01 00:00:00 EDT 2017
Interferons Induce Expression of SAMHD1 in Monocytes through Down-regulation of miR-181a and miR-30a.
The Journal of biological chemistry
Riess M,Fuchs NV,Idica A,Hamdorf M,Flory E,Pedersen IM,König R
Fri Jan 06 00:00:00 EST 2017
RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages.
Scientific reports
Pujantell M,Riveira-Muñoz E,Badia R,Castellví M,Garcia-Vidal E,Sirera G,Puig T,Ramirez C,Clotet B,Esté JA,Ballana E
Tue Oct 17 00:00:00 EDT 2017
Human galectin-9 on the porcine cells affects the cytotoxic activity of M1-differentiated THP-1 cells through inducing a shift in M2-differentiated THP-1 cells.
Xenotransplantation
Jung SH,Hwang JH,Kim SE,Kim YK,Park HC,Lee HT
200-04 was used in Western Blotting to suggest that hGal-9 has a reduction in M1-differentiated THP-1 cell cytotoxic activity-related acute immune rejection in pig-to-human xenotransplantation in addition to its role in lymphoid lineage immune cell regulation.
Sat Jul 01 00:00:00 EDT 2017
Butyrate and propionate inhibit antigen-specific CD8+ T cell activation by suppressing IL-12 production by antigen-presenting cells.
Scientific reports
Nastasi C,Fredholm S,Willerslev-Olsen A,Hansen M,Bonefeld CM,Geisler C,Andersen MH,Ødum N,Woetmann A
Mon Nov 06 00:00:00 EST 2017
Transcription factor Foxo1 is essential for IL-9 induction in T helper cells.
Nature communications
Malik S,Sadhu S,Elesela S,Pandey RP,Chawla AS,Sharma D,Panda L,Rathore D,Ghosh B,Ahuja V,Awasthi A
200-04 was used in Cell Culture to identify Foxo1 as a major transcription factor controlling the development of Th9 cells and other IL-9-producing T cells.
Mon Oct 09 00:00:00 EDT 2017
Transcription factor Foxo1 is essential for IL-9 induction in T helper cells.
Nature communications
Malik S,Sadhu S,Elesela S,Pandey RP,Chawla AS,Sharma D,Panda L,Rathore D,Ghosh B,Ahuja V,Awasthi A
200-04 was used in Cell Culture to identify Foxo1 as a major transcription factor controlling the development of Th9 cells and other IL-9-producing T cells.
Mon Oct 09 00:00:00 EDT 2017
IL-4 driven transcription factor FoxQ1 is expressed by monocytes in atopic dermatitis and stimulates monocyte migration.
Scientific reports
Ovsiy I,Riabov V,Manousaridis I,Michel J,Moganti K,Yin S,Liu T,Sticht C,Kremmer E,Harmsen MC,Goerdt S,Gratchev A,Kzhyshkowska J
Mon Dec 04 00:00:00 EST 2017
Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer.
Nature communications
Veglia F,Tyurin VA,Mohammadyani D,Blasi M,Duperret EK,Donthireddy L,Hashimoto A,Kapralov A,Amoscato A,Angelini R,Patel S,Alicea-Torres K,Weiner D,Murphy ME,Klein-Seetharaman J,Celis E,Kagan VE,Gabrilovich DI
Thu Dec 14 00:00:00 EST 2017
Identification of the novel 3' UTR sequences of human IL-21 mRNA as potential targets of miRNAs.
Scientific reports
Enomoto Y,Takagi R,Naito Y,Kiniwa T,Tanaka Y,Hamada-Tsutsumi S,Kawano M,Matsushita S,Ochiya T,Miyajima A
Thu Aug 10 00:00:00 EDT 2017
Development of a Curative Therapeutic Vaccine (TheraVac) for the Treatment of Large Established Tumors.
Scientific reports
Nie Y,Yang D,Trivett A,Han Z,Xin H,Chen X,Oppenheim JJ
Fri Oct 27 00:00:00 EDT 2017
Unbiased Quantitative Proteomics Reveals a Crucial Role of the Allergen Context for the Activation of Human Dendritic Cells.
Scientific reports
Strasser L,Dang HH,Schwarz H,Asam C,Ferreira F,Horejs-Hoeck J,Huber CG
Thu Nov 30 00:00:00 EST 2017
Epistatic interactions between mutations of TACI (TNFRSF13B) and TCF3 result in a severe primary immunodeficiency disorder and systemic lupus erythematosus.
Clinical & translational immunology
Ameratunga R,Koopmans W,Woon ST,Leung E,Lehnert K,Slade CA,Tempany JC,Enders A,Steele R,Browett P,Hodgkin PD,Bryant VL
Sun Oct 01 00:00:00 EDT 2017
Quantitative and organisational changes in mature extracellular matrix revealed through high-content imaging of total protein fluorescently stained in situ.
Scientific reports
Holdsworth G,Bon H,Bergin M,Qureshi O,Paveley R,Atkinson J,Huang L,Tewari R,Twomey B,Johnson T
Wed Aug 30 00:00:00 EDT 2017
Quantitative and organisational changes in mature extracellular matrix revealed through high-content imaging of total protein fluorescently stained in situ.
Scientific reports
Holdsworth G,Bon H,Bergin M,Qureshi O,Paveley R,Atkinson J,Huang L,Tewari R,Twomey B,Johnson T
Wed Aug 30 00:00:00 EDT 2017
Local and systemic immunomodulatory mechanisms triggered by Human Papillomavirus transformed cells: a potential role for G-CSF and neutrophils.
Scientific reports
Alvarez KLF,Beldi M,Sarmanho F,Rossetti RAM,Silveira CRF,Mota GR,Andreoli MA,Caruso EDC,Kamillos MF,Souza AM,Mastrocalla H,Clavijo-Salomon MA,Barbuto JAM,Lorenzi NP,Longatto-Filho A,Baracat E,Lopez RVM,Villa LL,Tacla M,Lepique AP
Mon Aug 21 00:00:00 EDT 2017
Sensing and responding to allergic response cytokines through a genetically encoded circuit.
Nature communications
Chassin H,Geering B,Schukur L,Ausländer D,Lang B,Fussenegger M
Tue Oct 24 00:00:00 EDT 2017
Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis.
The Journal of biological chemistry
Buzza MS,Johnson TA,Conway GD,Martin EW,Mukhopadhyay S,Shea-Donohue T,Antalis TM
Fri Jun 30 00:00:00 EDT 2017
Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation.
Nature communications
Infantino S,Light A,O'Donnell K,Bryant V,Avery DT,Elliott M,Tangye SG,Belz G,Mackay F,Richard S,Tarlinton D
Thu Oct 12 00:00:00 EDT 2017
Dectin-1 intracellular domain determines species-specific ligand spectrum by modulating receptor sensitivity.
The Journal of biological chemistry
Takano T,Motozono C,Imai T,Sonoda KH,Nakanishi Y,Yamasaki S
Fri Oct 13 00:00:00 EDT 2017
IL-4 rescues surface IgM expression in chronic lymphocytic leukemia.
Blood
Guo B,Zhang L,Chiorazzi N,Rothstein TL
Thu Jul 28 00:00:00 EDT 2016
Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.
The Journal of clinical investigation
Cantaert T,Schickel JN,Bannock JM,Ng YS,Massad C,Delmotte FR,Yamakawa N,Glauzy S,Chamberlain N,Kinnunen T,Menard L,Lavoie A,Walter JE,Notarangelo LD,Bruneau J,Al-Herz W,Kilic SS,Ochs HD,Cunningham-Rundles C,van der Burg M,Kuijpers TW,Kracker S,Kaneko H,Sekinaka Y,Nonoyama S,Durandy A,Meffre E
Tue Nov 01 00:00:00 EDT 2016
Stabilin-1 expression defines a subset of macrophages that mediate tissue homeostasis and prevent fibrosis in chronic liver injury.
Proceedings of the National Academy of Sciences of the United States of America
Rantakari P,Patten DA,Valtonen J,Karikoski M,Gerke H,Dawes H,Laurila J,Ohlmeier S,Elima K,Hübscher SG,Weston CJ,Jalkanen S,Adams DH,Salmi M,Shetty S
Tue Aug 16 00:00:00 EDT 2016
Large-scale sequence and structural comparisons of human naive and antigen-experienced antibody repertoires.
Proceedings of the National Academy of Sciences of the United States of America
DeKosky BJ,Lungu OI,Park D,Johnson EL,Charab W,Chrysostomou C,Kuroda D,Ellington AD,Ippolito GC,Gray JJ,Georgiou G
Tue May 10 00:00:00 EDT 2016
Engagement of SLAMF3 enhances CD4+ T-cell sensitivity to IL-2 and favors regulatory T-cell polarization in systemic lupus erythematosus.
Proceedings of the National Academy of Sciences of the United States of America
Comte D,Karampetsou MP,Kis-Toth K,Yoshida N,Bradley SJ,Mizui M,Kono M,Solomon JR,Kyttaris VC,Tsokos GC
Tue Aug 16 00:00:00 EDT 2016
Sarcoplasmic reticulum Ca(2+) ATPase 2 (SERCA2) reduces the migratory capacity of CCL21-treated monocyte-derived dendritic cells.
Experimental & molecular medicine
Hong CY,Lee HJ,Choi NR,Jung SH,Vo MC,Hoang MD,Kim HJ,Lee JJ
Fri Aug 19 00:00:00 EDT 2016
Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virus.
European journal of immunology
Pichulik T,Khatamzas E,Liu X,Brain O,Delmiro Garcia M,Leslie A,Danis B,Mayer A,Baban D,Ragoussis J,Weber AN,Simmons A
Fri Jan 01 00:00:00 EST 2016
Hepatic carcinoma-associated fibroblasts induce IDO-producing regulatory dendritic cells through IL-6-mediated STAT3 activation.
Oncogenesis
Cheng JT,Deng YN,Yi HM,Wang GY,Fu BS,Chen WJ,Liu W,Tai Y,Peng YW,Zhang Q
Mon Feb 22 00:00:00 EST 2016
Mesenchymal Stem Cells are Recruited and Activated into Carcinoma-Associated Fibroblasts by Prostate Cancer Microenvironment-Derived TGF-β1.
Stem cells (Dayton, Ohio)
Barcellos-de-Souza P,Comito G,Pons-Segura C,Taddei ML,Gori V,Becherucci V,Bambi F,Margheri F,Laurenzana A,Del Rosso M,Chiarugi P
Sat Oct 01 00:00:00 EDT 2016
Mesenchymal Stromal Cells Induce Peculiar Alternatively Activated Macrophages Capable of Dampening Both Innate and Adaptive Immune Responses.
Stem cells (Dayton, Ohio)
Chiossone L,Conte R,Spaggiari GM,Serra M,Romei C,Bellora F,Becchetti F,Andaloro A,Moretta L,Bottino C
Fri Jul 01 00:00:00 EDT 2016
LLT1 and CD161 Expression in Human Germinal Centers Promotes B Cell Activation and CXCR4 Downregulation.
Journal of immunology (Baltimore, Md. : 1950)
Llibre A,López-Macías C,Marafioti T,Mehta H,Partridge A,Kanzig C,Rivellese F,Galson JD,Walker LJ,Milne P,Phillips RE,Kelly DF,Freeman GJ,El Shikh ME,Klenerman P,Willberg CB
Tue Mar 01 00:00:00 EST 2016
Diverse HLA-I Peptide Repertoires of the APC Lines MUTZ3-Derived Immature and Mature Dendritic Cells and THP1-Derived Macrophages.
Journal of immunology (Baltimore, Md. : 1950)
Nyambura LW,Jarmalavicius S,Baleeiro RB,Walden P
Thu Sep 15 00:00:00 EDT 2016
MiR-381-3p Regulates the Antigen-Presenting Capability of Dendritic Cells and Represses Antituberculosis Cellular Immune Responses by Targeting CD1c.
Journal of immunology (Baltimore, Md. : 1950)
Wen Q,Zhou C,Xiong W,Su J,He J,Zhang S,Du X,Liu S,Wang J,Ma L
Fri Jul 15 00:00:00 EDT 2016
Efficient Culture of Human Naive and Memory B Cells for Use as APCs.
Journal of immunology (Baltimore, Md. : 1950)
Su KY,Watanabe A,Yeh CH,Kelsoe G,Kuraoka M
Tue Nov 15 00:00:00 EST 2016
Fc Receptor-like 5 Expression Distinguishes Two Distinct Subsets of Human Circulating Tissue-like Memory B Cells.
Journal of immunology (Baltimore, Md. : 1950)
Li H,Borrego F,Nagata S,Tolnay M
Sun May 15 00:00:00 EDT 2016
The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion.
Journal of immunology (Baltimore, Md. : 1950)
Tosh KW,Mittereder L,Bonne-Annee S,Hieny S,Nutman TB,Singer SM,Sher A,Jankovic D
Fri Jan 01 00:00:00 EST 2016
Development by Genetic Immunization of Monovalent Antibodies (Nanobodies) Behaving as Antagonists of the Human ChemR23 Receptor.
Journal of immunology (Baltimore, Md. : 1950)
Peyrassol X,Laeremans T,Gouwy M,Lahura V,Debulpaep M,Van Damme J,Steyaert J,Parmentier M,Langer I
Tue Mar 15 00:00:00 EDT 2016
Cytokine-Induced Glucocorticoid Resistance from Eosinophil Activation: Protein Phosphatase 5 Modulation of Glucocorticoid Receptor Phosphorylation and Signaling.
Journal of immunology (Baltimore, Md. : 1950)
Pazdrak K,Straub C,Maroto R,Stafford S,White WI,Calhoun WJ,Kurosky A
Tue Nov 15 00:00:00 EST 2016
Heparan Sulfate Proteoglycans Promote Telomerase Internalization and MHC Class II Presentation on Dendritic Cells.
Journal of immunology (Baltimore, Md. : 1950)
Galaine J,Kellermann G,Guillaume Y,Boidot R,Picard E,Loyon R,Queiroz L,Boullerot L,Beziaud L,Jary M,Mansi L,André C,Lethier L,Ségal-Bendirdjian E,Borg C,Godet Y,Adotévi O
Thu Sep 01 00:00:00 EDT 2016
Effects of autophagy regulation of tumor-associated macrophages on radiosensitivity of colorectal cancer cells.
Molecular medicine reports
Shao LN,Zhu BS,Xing CG,Yang XD,Young W,Cao JP
200-04 was used in Sample Preparation (FC/FACS) to study the importance of tumor‚associated macrophages (TAMs) in radiation resistance of colorectal cancer by investigating the effects of autophagy regulation of TAMs on the radiosensitivity of colorectal cancer cells using induced TAM formation from THP‚1 monocyte cells.
Tue Mar 01 00:00:00 EST 2016
Specific regulation of PRMT1 expression by PIAS1 and RKIP in BEAS-2B epithelia cells and HFL-1 fibroblasts in lung inflammation.
Scientific reports
Liu L,Sun Q,Bao R,Roth M,Zhong B,Lan X,Tian J,He Q,Li D,Sun J,Yang X,Lu S
Thu Feb 25 00:00:00 EST 2016
MiR-142-3p is a RANKL-dependent inducer of cell death in osteoclasts.
Scientific reports
Fordham JB,Guilfoyle K,Naqvi AR,Nares S
Tue Apr 26 00:00:00 EDT 2016
Ikaros Is a Negative Regulator of B1 Cell Development and Function.
The Journal of biological chemistry
Macias-Garcia A,Heizmann B,Sellars M,Marchal P,Dali H,Pasquali JL,Muller S,Kastner P,Chan S
Fri Apr 22 00:00:00 EDT 2016
Subgroup J avian leukosis virus infection of chicken dendritic cells induces apoptosis via the aberrant expression of microRNAs.
Scientific reports
Liu D,Dai M,Zhang X,Cao W,Liao M
Mon Feb 01 00:00:00 EST 2016
Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice.
Nature communications
Serr I,Fürst RW,Achenbach P,Scherm MG,Gökmen F,Haupt F,Sedlmeier EM,Knopff A,Shultz L,Willis RA,Ziegler AG,Daniel C
Tue Mar 15 00:00:00 EDT 2016
Sorting nexin 10 acting as a novel regulator of macrophage polarization mediates inflammatory response in experimental mouse colitis.
Scientific reports
You Y,Zhou C,Li D,Cao ZL,Shen W,Li WZ,Zhang S,Hu B,Shen X
Tue Feb 09 00:00:00 EST 2016
miRNA let-7b modulates macrophage polarization and enhances tumor-associated macrophages to promote angiogenesis and mobility in prostate cancer.
Scientific reports
Wang Z,Xu L,Hu Y,Huang Y,Zhang Y,Zheng X,Wang S,Wang Y,Yu Y,Zhang M,Yuan K,Min W
Mon May 09 00:00:00 EDT 2016
Bioelectric modulation of macrophage polarization.
Scientific reports
Li C,Levin M,Kaplan DL
Fri Feb 12 00:00:00 EST 2016
Identification of Differentially Expressed Long Non-coding RNAs in Polarized Macrophages.
Scientific reports
Huang Z,Luo Q,Yao F,Qing C,Ye J,Deng Y,Li J
Fri Jan 22 00:00:00 EST 2016
Cancer Cell-derived Exosomes Induce Mitogen-activated Protein Kinase-dependent Monocyte Survival by Transport of Functional Receptor Tyrosine Kinases.
The Journal of biological chemistry
Song X,Ding Y,Liu G,Yang X,Zhao R,Zhang Y,Zhao X,Anderson GJ,Nie G
Fri Apr 15 00:00:00 EDT 2016
Expression of the innate immune receptor LILRB5 on monocytes is associated with mycobacteria exposure.
Scientific reports
Hogan LE,Jones DC,Allen RL
Wed Feb 24 00:00:00 EST 2016
miR-24, miR-30b and miR-142-3p interfere with antigen processing and presentation by primary macrophages and dendritic cells.
Scientific reports
Naqvi AR,Fordham JB,Ganesh B,Nares S
Fri Sep 09 00:00:00 EDT 2016
Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry.
Nature communications
Bassani-Sternberg M,Bräunlein E,Klar R,Engleitner T,Sinitcyn P,Audehm S,Straub M,Weber J,Slotta-Huspenina J,Specht K,Martignoni ME,Werner A,Hein R,H Busch D,Peschel C,Rad R,Cox J,Mann M,Krackhardt AM
Mon Nov 21 00:00:00 EST 2016
CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients.
Scientific reports
Su S,Hu B,Shao J,Shen B,Du J,Du Y,Zhou J,Yu L,Zhang L,Chen F,Sha H,Cheng L,Meng F,Zou Z,Huang X,Liu B
Thu Jan 28 00:00:00 EST 2016
Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype.
Scientific reports
Harfuddin Z,Dharmadhikari B,Wong SC,Duan K,Poidinger M,Kwajah S,Schwarz H
Tue Jul 19 00:00:00 EDT 2016
Immunomodulation of Lactobacillus rhamnosus GG (LGG)-derived soluble factors on antigen-presenting cells of healthy blood donors.
Scientific reports
Fong FLY,Kirjavainen PV,El-Nezami H
Thu Mar 10 00:00:00 EST 2016
Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages.
Nature communications
Canton J,Schlam D,Breuer C,Gütschow M,Glogauer M,Grinstein S
Wed Apr 06 00:00:00 EDT 2016
STAT6 deficiency ameliorates Graves' disease severity by suppressing thyroid epithelial cell hyperplasia.
Cell death & disease
Jiang X,Zha B,Liu X,Liu R,Liu J,Huang E,Qian T,Liu J,Wang Z,Zhang D,Wang L,Chu Y
Thu Dec 01 00:00:00 EST 2016
PGE2 is a direct and robust mediator of anion/fluid secretion by human intestinal epithelial cells.
Scientific reports
Fujii S,Suzuki K,Kawamoto A,Ishibashi F,Nakata T,Murano T,Ito G,Shimizu H,Mizutani T,Oshima S,Tsuchiya K,Nakamura T,Araki A,Ohtsuka K,Okamoto R,Watanabe M
Wed Nov 09 00:00:00 EST 2016
Secukinumab, a novel anti-IL-17A antibody, shows low immunogenicity potential in human in vitro assays comparable to other marketed biotherapeutics with low clinical immunogenicity.
mAbs
Karle A,Spindeldreher S,Kolbinger F
200-04 was used in Cell Culture to evaluate its immunogenicity potential by applying 2 different in vitro assays: T-cell activation and major histocompatibility complex-associated peptide proteomics (MAPPs).
Tue Dec 13 00:00:00 EST 2016
MARCH8 inhibits HIV-1 infection by reducing virion incorporation of envelope glycoproteins.
Nature medicine
Tada T,Zhang Y,Koyama T,Tobiume M,Tsunetsugu-Yokota Y,Yamaoka S,Fujita H,Tokunaga K
Tue Dec 01 00:00:00 EST 2015
Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity.
Nature
Carmi Y,Spitzer MH,Linde IL,Burt BM,Prestwood TR,Perlman N,Davidson MG,Kenkel JA,Segal E,Pusapati GV,Bhattacharya N,Engleman EG
Thu May 07 00:00:00 EDT 2015
A SnoRNA-derived piRNA interacts with human interleukin-4 pre-mRNA and induces its decay in nuclear exosomes.
Nucleic acids research
Zhong F,Zhou N,Wu K,Guo Y,Tan W,Zhang H,Zhang X,Geng G,Pan T,Luo H,Zhang Y,Xu Z,Liu J,Liu B,Gao W,Liu C,Ren L,Li J,Zhou J,Zhang H
200-04 was used in Sample Preparation (Western Blotting) to demonstrate a novel piRNA mechanism in regulating gene expression in highly differentiated somatic cells.
Wed Dec 02 00:00:00 EST 2015
Bee venom processes human skin lipids for presentation by CD1a.
The Journal of experimental medicine
Bourgeois EA,Subramaniam S,Cheng TY,De Jong A,Layre E,Ly D,Salimi M,Legaspi A,Modlin RL,Salio M,Cerundolo V,Moody DB,Ogg G
Mon Feb 09 00:00:00 EST 2015
Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow.
The Journal of experimental medicine
Lee J,Breton G,Oliveira TY,Zhou YJ,Aljoufi A,Puhr S,Cameron MJ,Sékaly RP,Nussenzweig MC,Liu K
Mon Mar 09 00:00:00 EDT 2015
Glycoprotein B7-H3 overexpression and aberrant glycosylation in oral cancer and immune response.
Proceedings of the National Academy of Sciences of the United States of America
Chen JT,Chen CH,Ku KL,Hsiao M,Chiang CP,Hsu TL,Chen MH,Wong CH
Tue Oct 20 00:00:00 EDT 2015
Low-affinity TCR engagement drives IL-2-dependent post-thymic maintenance of naive CD4+ T cells in aged humans.
Aging cell
van der Geest KS,Abdulahad WH,Teteloshvili N,Tete SM,Peters JH,Horst G,Lorencetti PG,Bos NA,Lambeck A,Roozendaal C,Kroesen BJ,Koenen HJ,Joosten I,Brouwer E,Boots AM
Thu Oct 01 00:00:00 EDT 2015
Cross-reactivity of hepatitis C virus specific vaccine-induced T cells at immunodominant epitopes.
European journal of immunology
Kelly C,Swadling L,Brown A,Capone S,Folgori A,Salio M,Klenerman P,Barnes E
Thu Jan 01 00:00:00 EST 2015
Human monocyte-derived dendritic cells turn into foamy dendritic cells with IL-17A.
Journal of lipid research
Salvatore G,Bernoud-Hubac N,Bissay N,Debard C,Daira P,Meugnier E,Proamer F,Hanau D,Vidal H,Aricò M,Delprat C,Mahtouk K
Mon Jun 01 00:00:00 EDT 2015
A transendocytosis model of CTLA-4 function predicts its suppressive behavior on regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Hou TZ,Qureshi OS,Wang CJ,Baker J,Young SP,Walker LS,Sansom DM
Sun Mar 01 00:00:00 EST 2015
Inhibiting STAT5 by the BET bromodomain inhibitor JQ1 disrupts human dendritic cell maturation.
Journal of immunology (Baltimore, Md. : 1950)
Toniolo PA,Liu S,Yeh JE,Moraes-Vieira PM,Walker SR,Vafaizadeh V,Barbuto JA,Frank DA
Wed Apr 01 00:00:00 EDT 2015
IL-7 Abrogates the Immunosuppressive Function of Human Double-Negative T Cells by Activating Akt/mTOR Signaling.
Journal of immunology (Baltimore, Md. : 1950)
Allgäuer A,Schreiner E,Ferrazzi F,Ekici AB,Gerbitz A,Mackensen A,Völkl S
Thu Oct 01 00:00:00 EDT 2015
Ex vivo-expanded but not in vitro-induced human regulatory T cells are candidates for cell therapy in autoimmune diseases thanks to stable demethylation of the FOXP3 regulatory T cell-specific demethylated region.
Journal of immunology (Baltimore, Md. : 1950)
Rossetti M,Spreafico R,Saidin S,Chua C,Moshref M,Leong JY,Tan YK,Thumboo J,van Loosdregt J,Albani S
Thu Jan 01 00:00:00 EST 2015
Genetic vaccines to potentiate the effective CD103+ dendritic cell-mediated cross-priming of antitumor immunity.
Journal of immunology (Baltimore, Md. : 1950)
Zhang Y,Chen G,Liu Z,Tian S,Zhang J,Carey CD,Murphy KM,Storkus WJ,Falo LD,You Z
Mon Jun 15 00:00:00 EDT 2015
Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways.
Journal of immunology (Baltimore, Md. : 1950)
Mattiola I,Pesant M,Tentorio PF,Molgora M,Marcenaro E,Lugli E,Locati M,Mavilio D
Tue Sep 15 00:00:00 EDT 2015
Protection of human myeloid dendritic cell subsets against influenza A virus infection is differentially regulated upon TLR stimulation.
Journal of immunology (Baltimore, Md. : 1950)
Baharom F,Thomas S,Bieder A,Hellmér M,Volz J,Sandgren KJ,McInerney GM,Karlsson Hedestam GB,Mellman I,Smed-Sörensen A
Fri May 01 00:00:00 EDT 2015
TGF-β1, but not bone morphogenetic proteins, activates Smad1/5 pathway in primary human macrophages and induces expression of proatherogenic genes.
Journal of immunology (Baltimore, Md. : 1950)
Nurgazieva D,Mickley A,Moganti K,Ming W,Ovsyi I,Popova A,Awad K,Wang N,Bieback K,Goerdt S,Kzhyshkowska J,Gratchev A
Thu Jan 15 00:00:00 EST 2015
TLR-Stimulated Neutrophils Instruct NK Cells To Trigger Dendritic Cell Maturation and Promote Adaptive T Cell Responses.
Journal of immunology (Baltimore, Md. : 1950)
Riise RE,Bernson E,Aurelius J,Martner A,Pesce S,Della Chiesa M,Marcenaro E,Bylund J,Hellstrand K,Moretta L,Moretta A,Thorén FB
Sat Aug 01 00:00:00 EDT 2015
Identification of Thiostrepton as a Novel Inhibitor for Psoriasis-like Inflammation Induced by TLR7-9.
Journal of immunology (Baltimore, Md. : 1950)
Lai CY,Yeh DW,Lu CH,Liu YL,Huang LR,Kao CY,Chen HY,Huang CY,Chang CH,Luo Y,Xiang R,Chuang TH
Thu Oct 15 00:00:00 EDT 2015
Sos1 Regulates Macrophage Podosome Assembly and Macrophage Invasive Capacity.
Journal of immunology (Baltimore, Md. : 1950)
Baruzzi A,Remelli S,Lorenzetto E,Sega M,Chignola R,Berton G
Sun Nov 15 00:00:00 EST 2015
The Novel Receptor C5aR2 Is Required for C5a-Mediated Human Mast Cell Adhesion, Migration, and Proinflammatory Mediator Production.
Journal of immunology (Baltimore, Md. : 1950)
Pundir P,MacDonald CA,Kulka M
Tue Sep 15 00:00:00 EDT 2015
miR-24, miR-30b, and miR-142-3p regulate phagocytosis in myeloid inflammatory cells.
Journal of immunology (Baltimore, Md. : 1950)
Naqvi AR,Fordham JB,Nares S
Sun Feb 15 00:00:00 EST 2015
Chronic lymphocytic leukemia cells express CD38 in response to Th1 cell-derived IFN-γ by a T-bet-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950)
Bürgler S,Gimeno A,Parente-Ribes A,Wang D,Os A,Devereux S,Jebsen P,Bogen B,Tjønnfjord GE,Munthe LA
Thu Jan 15 00:00:00 EST 2015
Cutting Edge: AhR Is a Molecular Target of Calcitriol in Human T Cells.
Journal of immunology (Baltimore, Md. : 1950)
Takami M,Fujimaki K,Nishimura MI,Iwashima M
Tue Sep 15 00:00:00 EDT 2015
IL-4 Downregulates IL-1β and IL-6 and Induces GATA3 in Psoriatic Epidermal Cells: Route of Action of a Th2 Cytokine.
Journal of immunology (Baltimore, Md. : 1950)
Onderdijk AJ,Baerveldt EM,Kurek D,Kant M,Florencia EF,Debets R,Prens EP
Sat Aug 15 00:00:00 EDT 2015
Induced conformational change in human IL-4 upon binding of a signal-neutralizing DARPin.
Proteins
Obmolova G,Teplyakov A,Malia TJ,Keough E,Luo J,Sweet R,Jacobs SA,Yi F,Hippensteel R,O'Neil KT,Gilliland GL
Mon Jun 01 00:00:00 EDT 2015
Batf is important for IL-4 expression in T follicular helper cells.
Nature communications
Sahoo A,Alekseev A,Tanaka K,Obertas L,Lerman B,Haymaker C,Clise-Dwyer K,McMurray JS,Nurieva R
Mon Aug 17 00:00:00 EDT 2015
IL-10 induces the development of immunosuppressive CD14(+)HLA-DR(low/-) monocytes in B-cell non-Hodgkin lymphoma.
Blood cancer journal
Xiu B,Lin Y,Grote DM,Ziesmer SC,Gustafson MP,Maas ML,Zhang Z,Dietz AB,Porrata LF,Novak AJ,Liang AB,Yang ZZ,Ansell SM
Fri Jul 31 00:00:00 EDT 2015
Progranulin and a five transmembrane domain-containing receptor-like gene are the key components in receptor activator of nuclear factor κB (RANK)-dependent formation of multinucleated osteoclasts.
The Journal of biological chemistry
Oh J,Kim JY,Kim HS,Oh JC,Cheon YH,Park J,Yoon KH,Lee MS,Youn BS
Fri Jan 23 00:00:00 EST 2015
MicroRNA-146a and microRNA-146b regulate human dendritic cell apoptosis and cytokine production by targeting TRAF6 and IRAK1 proteins.
The Journal of biological chemistry
Park H,Huang X,Lu C,Cairo MS,Zhou X
Fri Jan 30 00:00:00 EST 2015
Integrated Transcriptomics Establish Macrophage Polarization Signatures and have Potential Applications for Clinical Health and Disease.
Scientific reports
Becker M,De Bastiani MA,Parisi MM,Guma FT,Markoski MM,Castro MA,Kaplan MH,Barbé-Tuana FM,Klamt F
Tue Aug 25 00:00:00 EDT 2015
miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program.
Nature communications
Su S,Zhao Q,He C,Huang D,Liu J,Chen F,Chen J,Liao JY,Cui X,Zeng Y,Yao H,Su F,Liu Q,Jiang S,Song E
Mon Oct 05 00:00:00 EDT 2015
PD-1 and Tim-3 pathways are associated with regulatory CD8+ T-cell function in decidua and maintenance of normal pregnancy.
Cell death & disease
Wang SC,Li YH,Piao HL,Hong XW,Zhang D,Xu YY,Tao Y,Wang Y,Yuan MM,Li DJ,Du MR
Thu May 07 00:00:00 EDT 2015
The effect of short-chain fatty acids on human monocyte-derived dendritic cells.
Scientific reports
Nastasi C,Candela M,Bonefeld CM,Geisler C,Hansen M,Krejsgaard T,Biagi E,Andersen MH,Brigidi P,Ødum N,Litman T,Woetmann A
Fri Nov 06 00:00:00 EST 2015
High affinity targeting of CD23 inhibits IgE synthesis in human B cells.
Immunity, inflammation and disease
Fellmann M,Buschor P,Röthlisberger S,Zellweger F,Vogel M
Tue Dec 01 00:00:00 EST 2015
Mica Nanoparticle, STB-HO Eliminates the Human Breast Carcinoma Cells by Regulating the Interaction of Tumor with its Immune Microenvironment.
Scientific reports
Kang TW,Kim HS,Lee BC,Shin TH,Choi SW,Kim YJ,Lee HY,Jung YK,Seo KW,Kang KS
Thu Dec 03 00:00:00 EST 2015
Slit2N Inhibits Transmission of HIV-1 from Dendritic Cells to T-cells by Modulating Novel Cytoskeletal Elements.
Scientific reports
Shrivastava A,Prasad A,Kuzontkoski PM,Yu J,Groopman JE
Thu Nov 19 00:00:00 EST 2015
Galectin-1 regulates tissue exit of specific dendritic cell populations.
The Journal of biological chemistry
Thiemann S,Man JH,Chang MH,Lee B,Baum LG
Fri Sep 11 00:00:00 EDT 2015
Immunity induced by a broad class of inorganic crystalline materials is directly controlled by their chemistry.
The Journal of experimental medicine
Williams GR,Fierens K,Preston SG,Lunn D,Rysnik O,De Prijck S,Kool M,Buckley HC,Lambrecht BN,O'Hare D,Austyn JM
Mon Jun 02 00:00:00 EDT 2014
A CD8 T cell/indoleamine 2,3-dioxygenase axis is required for mesenchymal stem cell suppression of human systemic lupus erythematosus.
Arthritis & rheumatology (Hoboken, N.J.)
Wang D,Feng X,Lu L,Konkel JE,Zhang H,Chen Z,Li X,Gao X,Lu L,Shi S,Chen W,Sun L
Fri Aug 01 00:00:00 EDT 2014
Dysfunction of dendritic cells in aged C57BL/6 mice leads to failure of natural killer cell activation and of tumor eradication.
Proceedings of the National Academy of Sciences of the United States of America
Guo Z,Tilburgs T,Wong B,Strominger JL
Tue Sep 30 00:00:00 EDT 2014
Adaptive immune contexture at the tumour site and downmodulation of circulating myeloid-derived suppressor cells in the response of solitary fibrous tumour patients to anti-angiogenic therapy.
British journal of cancer
Tazzari M,Negri T,Rini F,Vergani B,Huber V,Villa A,Dagrada P,Colombo C,Fiore M,Gronchi A,Stacchiotti S,Casali PG,Pilotti S,Rivoltini L,Castelli C
Tue Sep 23 00:00:00 EDT 2014
Phorbol myristate acetate, but not CD40L, induces the differentiation of CLL B cells into Ab-secreting cells.
Immunology and cell biology
Ghamlouch H,Ouled-Haddou H,Guyart A,Regnier A,Trudel S,Claisse JF,Fuentes V,Royer B,Marolleau JP,Gubler B
Fri Aug 01 00:00:00 EDT 2014
Mechanistic target of rapamycin complex 1 expands Th17 and IL-4+ CD4-CD8- double-negative T cells and contracts regulatory T cells in systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950)
Kato H,Perl A
Thu May 01 00:00:00 EDT 2014
Human dendritic cells exhibit a pronounced type I IFN signature following Leishmania major infection that is required for IL-12 induction.
Journal of immunology (Baltimore, Md. : 1950)
Favila MA,Geraci NS,Zeng E,Harker B,Condon D,Cotton RN,Jayakumar A,Tripathi V,McDowell MA
Sun Jun 15 00:00:00 EDT 2014
Mycobacterium tuberculosis impairs dendritic cell functions through the serine hydrolase Hip1.
Journal of immunology (Baltimore, Md. : 1950)
Madan-Lala R,Sia JK,King R,Adekambi T,Monin L,Khader SA,Pulendran B,Rengarajan J
Thu May 01 00:00:00 EDT 2014
Eosinophils regulate peripheral B cell numbers in both mice and humans.
Journal of immunology (Baltimore, Md. : 1950)
Wong TW,Doyle AD,Lee JJ,Jelinek DF
Tue Apr 15 00:00:00 EDT 2014
Activin A as a mediator of NK-dendritic cell functional interactions.
Journal of immunology (Baltimore, Md. : 1950)
Seeger P,Bosisio D,Parolini S,Badolato R,Gismondi A,Santoni A,Sozzani S
Sat Feb 01 00:00:00 EST 2014
Glycoengineering of therapeutic antibodies enhances monocyte/macrophage-mediated phagocytosis and cytotoxicity.
Journal of immunology (Baltimore, Md. : 1950)
Herter S,Birk MC,Klein C,Gerdes C,Umana P,Bacac M
Sat Mar 01 00:00:00 EST 2014
IL-27, a cytokine, and IFN-λ1, a type III IFN, are coordinated to regulate virus replication through type I IFN.
Journal of immunology (Baltimore, Md. : 1950)
Cao Y,Zhang R,Zhang W,Zhu C,Yu Y,Song Y,Wang Q,Bai L,Liu Y,Wu K,Wu J
Wed Jan 15 00:00:00 EST 2014
RNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events.
Journal of immunology (Baltimore, Md. : 1950)
Colak E,Leslie A,Zausmer K,Khatamzas E,Kubarenko AV,Pichulik T,Klimosch SN,Mayer A,Siggs O,Hector A,Fischer R,Klesser B,Rautanen A,Frank M,Hill AV,Manoury B,Beutler B,Hartl D,Simmons A,Weber AN
Sun Jun 15 00:00:00 EDT 2014
Chronic exposure to glucocorticoids shapes gene expression and modulates innate and adaptive activation pathways in macrophages with distinct changes in leukocyte attraction.
Journal of immunology (Baltimore, Md. : 1950)
van de Garde MD,Martinez FO,Melgert BN,Hylkema MN,Jonkers RE,Hamann J
Sat Feb 01 00:00:00 EST 2014
Human Th2 but not Th9 cells release IL-31 in a STAT6/NF-κB-dependent way.
Journal of immunology (Baltimore, Md. : 1950)
Maier E,Werner D,Duschl A,Bohle B,Horejs-Hoeck J
Tue Jul 15 00:00:00 EDT 2014
Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Balan S,Ollion V,Colletti N,Chelbi R,Montanana-Sanchis F,Liu H,Vu Manh TP,Sanchez C,Savoret J,Perrot I,Doffin AC,Fossum E,Bechlian D,Chabannon C,Bogen B,Asselin-Paturel C,Shaw M,Soos T,Caux C,Valladeau-Guilemond J,Dalod M
Fri Aug 15 00:00:00 EDT 2014
Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation.
Journal of immunology (Baltimore, Md. : 1950)
Kawasaki N,Rillahan CD,Cheng TY,Van Rhijn I,Macauley MS,Moody DB,Paulson JC
Fri Aug 15 00:00:00 EDT 2014
Engagement of SLAMF2/CD48 prolongs the time frame of effective T cell activation by supporting mature dendritic cell survival.
Journal of immunology (Baltimore, Md. : 1950)
Kis-Toth K,Tsokos GC
Thu May 01 00:00:00 EDT 2014
Cancer-initiating cells from colorectal cancer patients escape from T cell-mediated immunosurveillance in vitro through membrane-bound IL-4.
Journal of immunology (Baltimore, Md. : 1950)
Volonté A,Di Tomaso T,Spinelli M,Todaro M,Sanvito F,Albarello L,Bissolati M,Ghirardelli L,Orsenigo E,Ferrone S,Doglioni C,Stassi G,Dellabona P,Staudacher C,Parmiani G,Maccalli C
Wed Jan 01 00:00:00 EST 2014
A new tool to quantify receptor recruitment to cell contact sites during host-pathogen interaction.
PLoS computational biology
Graus MS,Pehlke C,Wester MJ,Davidson LB,Steinberg SL,Neumann AK
200-04 was used in Cell Culture to evaluate the use of 3D multichannel laser scanning confocal microscopy to quantify receptor recruitment between primary human dendritic cells and fungal pathogens.
Thu May 01 00:00:00 EDT 2014
Interaction between pancreatic cancer cells and tumor-associated macrophages promotes the invasion of pancreatic cancer cells and the differentiation and migration of macrophages.
IUBMB life
Meng F,Li C,Li W,Gao Z,Guo K,Song S
200-04 was used in Cell Culture to evaluate the impact of pancreatic cancer cell interaction with macrophages on the differentiation and function of macrophages and the behaviors of pancreatic cancer cells in vitro to show that the interaction between pancreatic cancer cells and tumor-associated macrophages may play a pivotal role in the progression of pancreatic cancer.
Mon Dec 01 00:00:00 EST 2014
Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells.
PloS one
Kongsbak M,von Essen MR,Boding L,Levring TB,Schjerling P,Lauritsen JP,Woetmann A,Ødum N,Bonefeld CM,Geisler C
200-04 was used in Cell Culture to determine if and how 1,25(OH)2D3 by itself regulates vitamin D receptor (VDR) expression in human CD4+ T cells.
Thu Jun 04 00:00:00 EDT 2015
Regulation of activation-associated microRNA accumulation rates during monocyte-to-macrophage differentiation.
The Journal of biological chemistry
Eigsti RL,Sudan B,Wilson ME,Graff JW
Fri Oct 10 00:00:00 EDT 2014
Thrombin cleavage of osteopontin disrupts a pro-chemotactic sequence for dendritic cells, which is compensated by the release of its pro-chemotactic C-terminal fragment.
The Journal of biological chemistry
Shao Z,Morser J,Leung LLK
Fri Sep 26 00:00:00 EDT 2014
Low molecular weight hyaluronan activates cytosolic phospholipase A2α and eicosanoid production in monocytes and macrophages.
The Journal of biological chemistry
Sokolowska M,Chen LY,Eberlein M,Martinez-Anton A,Liu Y,Alsaaty S,Qi HY,Logun C,Horton M,Shelhamer JH
Fri Feb 14 00:00:00 EST 2014
Negative regulation of Toll-like receptor-4 signaling through the binding of glycosylphosphatidylinositol-anchored glycoprotein, CD14, with the sialic acid-binding lectin, CD33.
The Journal of biological chemistry
Ishida A,Akita K,Mori Y,Tanida S,Toda M,Inoue M,Nakada H
Fri Sep 05 00:00:00 EDT 2014
High-throughput identification and dendritic cell-based functional validation of MHC class I-restricted Mycobacterium tuberculosis epitopes.
Scientific reports
Nair SK,Tomaras GD,Sales AP,Boczkowski D,Chan C,Plonk K,Cai Y,Dannull J,Kepler TB,Pruitt SK,Weinhold KJ
Wed Apr 23 00:00:00 EDT 2014
The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release.
Immunity
Brain O,Owens BM,Pichulik T,Allan P,Khatamzas E,Leslie A,Steevels T,Sharma S,Mayer A,Catuneanu AM,Morton V,Sun MY,Jewell D,Coccia M,Harrison O,Maloy K,Schönefeldt S,Bornschein S,Liston A,Simmons A
Thu Sep 19 00:00:00 EDT 2013
Src-kinase inhibitors sensitize human cells of myeloid origin to Toll-like-receptor-induced interleukin 12 synthesis.
Blood
Wölfl M,Schwinn S,Yoo YE,Reß ML,Braun M,Chopra M,Schreiber SC,Ayala VI,Ohlen C,Eyrich M,Beilhack A,Schlegel PG
Thu Aug 15 00:00:00 EDT 2013
CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia.
Blood
Fedorchenko O,Stiefelhagen M,Peer-Zada AA,Barthel R,Mayer P,Eckei L,Breuer A,Crispatzu G,Rosen N,Landwehr T,Lilienthal N,Möllmann M,Montesinos-Rongen M,Heukamp L,Dürig J,Hallek M,Fingerle-Rowson G,Herling M
Thu May 16 00:00:00 EDT 2013
Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences.
Blood
Martinez FO,Helming L,Milde R,Varin A,Melgert BN,Draijer C,Thomas B,Fabbri M,Crawshaw A,Ho LP,Ten Hacken NH,Cobos Jiménez V,Kootstra NA,Hamann J,Greaves DR,Locati M,Mantovani A,Gordon S
Thu Feb 28 00:00:00 EST 2013
Regulation of dendritic cell activation by microRNA let-7c and BLIMP1.
The Journal of clinical investigation
Kim SJ,Gregersen PK,Diamond B
Fri Feb 01 00:00:00 EST 2013
Identification of human CCR8 as a CCL18 receptor.
The Journal of experimental medicine
Islam SA,Ling MF,Leung J,Shreffler WG,Luster AD
Mon Sep 23 00:00:00 EDT 2013
MHC II tetramers visualize human CD4+ T cell responses to Epstein-Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response.
The Journal of experimental medicine
Long HM,Chagoury OL,Leese AM,Ryan GB,James E,Morton LT,Abbott RJ,Sabbah S,Kwok W,Rickinson AB
Mon May 06 00:00:00 EDT 2013
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression.
Proceedings of the National Academy of Sciences of the United States of America
Yamaguchi T,Kishi A,Osaki M,Morikawa H,Prieto-Martin P,Wing K,Saito T,Sakaguchi S
Tue Jun 04 00:00:00 EDT 2013
Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation.
Proceedings of the National Academy of Sciences of the United States of America
Kawasaki N,Vela JL,Nycholat CM,Rademacher C,Khurana A,van Rooijen N,Crocker PR,Kronenberg M,Paulson JC
Tue May 07 00:00:00 EDT 2013
An upstream open reading frame modulates ebola virus polymerase translation and virus replication.
PLoS pathogens
Shabman RS,Hoenen T,Groseth A,Jabado O,Binning JM,Amarasinghe GK,Feldmann H,Basler CF
Tue Jan 01 00:00:00 EST 2013
The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer.
Journal of immunology (Baltimore, Md. : 1950)
Mimura K,Shiraishi K,Mueller A,Izawa S,Kua LF,So J,Yong WP,Fujii H,Seliger B,Kiessling R,Kono K
Sun Dec 15 00:00:00 EST 2013
Mesenchymal stem cells tune the development of monocyte-derived dendritic cells toward a myeloid-derived suppressive phenotype through growth-regulated oncogene chemokines.
Journal of immunology (Baltimore, Md. : 1950)
Chen HW,Chen HY,Wang LT,Wang FH,Fang LW,Lai HY,Chen HH,Lu J,Hung MS,Cheng Y,Chen MY,Liu SJ,Chong P,Lee OK,Hsu SC
Wed May 15 00:00:00 EDT 2013
Adam8 limits the development of allergic airway inflammation in mice.
Journal of immunology (Baltimore, Md. : 1950)
Knolle MD,Nakajima T,Hergrueter A,Gupta K,Polverino F,Craig VJ,Fyfe SE,Zahid M,Permaul P,Cernadas M,Montano G,Tesfaigzi Y,Sholl L,Kobzik L,Israel E,Owen CA
Sat Jun 15 00:00:00 EDT 2013
Cross talk between follicular Th cells and tumor cells in human follicular lymphoma promotes immune evasion in the tumor microenvironment.
Journal of immunology (Baltimore, Md. : 1950)
Rawal S,Chu F,Zhang M,Park HJ,Nattamai D,Kannan S,Sharma R,Delgado D,Chou T,Lin HY,Baladandayuthapani V,Luong A,Vega F,Fowler N,Dong C,Davis RE,Neelapu SS
Sat Jun 15 00:00:00 EDT 2013
Dendritic cell reprogramming by endogenously produced lactic acid.
Journal of immunology (Baltimore, Md. : 1950)
Nasi A,Fekete T,Krishnamurthy A,Snowden S,Rajnavölgyi E,Catrina AI,Wheelock CE,Vivar N,Rethi B
Sun Sep 15 00:00:00 EDT 2013
IL-21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp-1 in human B cells.
Journal of immunology (Baltimore, Md. : 1950)
Ding BB,Bi E,Chen H,Yu JJ,Ye BH
Fri Feb 15 00:00:00 EST 2013
PTPN22 modulates macrophage polarization and susceptibility to dextran sulfate sodium-induced colitis.
Journal of immunology (Baltimore, Md. : 1950)
Chang HH,Miaw SC,Tseng W,Sun YW,Liu CC,Tsao HW,Ho IC
Sun Sep 01 00:00:00 EDT 2013
Human CD1c⁺ myeloid dendritic cells acquire a high level of retinoic acid-producing capacity in response to vitamin D₃.
Journal of immunology (Baltimore, Md. : 1950)
Sato T,Kitawaki T,Fujita H,Iwata M,Iyoda T,Inaba K,Ohteki T,Hasegawa S,Kawada K,Sakai Y,Ikeuchi H,Nakase H,Niwa A,Takaori-Kondo A,Kadowaki N
Sun Sep 15 00:00:00 EDT 2013
Restriction of HIV-1 replication in primary macrophages by IL-12 and IL-18 through the upregulation of SAMHD1.
Journal of immunology (Baltimore, Md. : 1950)
Pauls E,Jimenez E,Ruiz A,Permanyer M,Ballana E,Costa H,Nascimiento R,Parkhouse RM,Peña R,Riveiro-Muñoz E,Martinez MA,Clotet B,Esté JA,Bofill M
Wed May 01 00:00:00 EDT 2013
Lipoproteins are major targets of the polyclonal human T cell response to Mycobacterium tuberculosis.
Journal of immunology (Baltimore, Md. : 1950)
Seshadri C,Turner MT,Lewinsohn DM,Moody DB,Van Rhijn I
Tue Jan 01 00:00:00 EST 2013
Association of Neisseria gonorrhoeae Opa(CEA) with dendritic cells suppresses their ability to elicit an HIV-1-specific T cell memory response.
PloS one
Yu Q,Chow EM,McCaw SE,Hu N,Byrd D,Amet T,Hu S,Ostrowski MA,Gray-Owen SD
Thu Aug 08 00:00:00 EDT 2013
Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells.
PloS one
Fossati-Jimack L,Ling GS,Cortini A,Szajna M,Malik TH,McDonald JU,Pickering MC,Cook HT,Taylor PR,Botto M
Fri Sep 27 00:00:00 EDT 2013
Immunologic targeting of FOXP3 in inflammatory breast cancer cells.
PloS one
Nair S,Aldrich AJ,McDonnell E,Cheng Q,Aggarwal A,Patel P,Williams MM,Boczkowski D,Lyerly HK,Morse MA,Devi GR
Tue Jul 09 00:00:00 EDT 2013
Chemoresistance of human monocyte-derived dendritic cells is regulated by IL-17A.
PloS one
Olsson Åkefeldt S,Maisse C,Belot A,Mazzorana M,Salvatore G,Bissay N,Jurdic P,Aricò M,Rabourdin-Combe C,Henter JI,Delprat C
Tue Aug 13 00:00:00 EDT 2013
Toll-like receptor 4 engagement drives differentiation of human and murine dendritic cells from a pro- into an anti-inflammatory mode.
PloS one
Luger R,Valookaran S,Knapp N,Vizzardelli C,Dohnal AM,Felzmann T
Fri Sep 06 00:00:00 EDT 2013
The two-component adjuvant IC31® boosts type i interferon production of human monocyte-derived dendritic cells via ligation of endosomal TLRs.
PloS one
Szabo A,Gogolak P,Pazmandi K,Kis-Toth K,Riedl K,Wizel B,Lingnau K,Bacsi A,Rethi B,Rajnavolgyi E
Mon Dec 02 00:00:00 EST 2013
Plasma amino acids imbalance in cirrhotic patients disturbs the tricarboxylic acid cycle of dendritic cell.
Scientific reports
Kakazu E,Kondo Y,Kogure T,Ninomiya M,Kimura O,Ueno Y,Shimosegawa T
Tue Dec 10 00:00:00 EST 2013
Selective inhibition of phosphoinositide 3-kinase p110α preserves lymphocyte function.
The Journal of biological chemistry
So L,Yea SS,Oak JS,Lu M,Manmadhan A,Ke QH,Janes MR,Kessler LV,Kucharski JM,Li LS,Martin MB,Ren P,Jessen KA,Liu Y,Rommel C,Fruman DA
Fri Feb 22 00:00:00 EST 2013
Pancreatic tumors and immature immunosuppressive myeloid cells in blood and spleen: role of inhibitory co-stimulatory molecules PDL1 and CTLA4. An in vivo and in vitro study.
PloS one
Basso D,Fogar P,Falconi M,Fadi E,Sperti C,Frasson C,Greco E,Tamburrino D,Teolato S,Moz S,Bozzato D,Pelloso M,Padoan A,De Franchis G,Gnatta E,Facco M,Zambon CF,Navaglia F,Pasquali C,Basso G,Semenzato G,Pedrazzoli S,Pederzoli P,Plebani M
Fri Sep 06 00:00:00 EDT 2013
Functional STAT3 deficiency compromises the generation of human T follicular helper cells.
Blood
Ma CS,Avery DT,Chan A,Batten M,Bustamante J,Boisson-Dupuis S,Arkwright PD,Kreins AY,Averbuch D,Engelhard D,Magdorf K,Kilic SS,Minegishi Y,Nonoyama S,French MA,Choo S,Smart JM,Peake J,Wong M,Gray P,Cook MC,Fulcher DA,Casanova JL,Deenick EK,Tangye SG
Thu Apr 26 00:00:00 EDT 2012
Mast cells play a protumorigenic role in primary cutaneous lymphoma.
Blood
Rabenhorst A,Schlaak M,Heukamp LC,Förster A,Theurich S,von Bergwelt-Baildon M,Büttner R,Kurschat P,Mauch C,Roers A,Hartmann K
Thu Sep 06 00:00:00 EDT 2012
DC-SIGN, C1q, and gC1qR form a trimolecular receptor complex on the surface of monocyte-derived immature dendritic cells.
Blood
Hosszu KK,Valentino A,Vinayagasundaram U,Vinayagasundaram R,Joyce MG,Ji Y,Peerschke EI,Ghebrehiwet B
Thu Aug 09 00:00:00 EDT 2012
Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology.
Blood
Pello OM,De Pizzol M,Mirolo M,Soucek L,Zammataro L,Amabile A,Doni A,Nebuloni M,Swigart LB,Evan GI,Mantovani A,Locati M
Thu Jan 12 00:00:00 EST 2012
Notch is active in Langerhans cell histiocytosis and confers pathognomonic features on dendritic cells.
Blood
Hutter C,Kauer M,Simonitsch-Klupp I,Jug G,Schwentner R,Leitner J,Bock P,Steinberger P,Bauer W,Carlesso N,Minkov M,Gadner H,Stingl G,Kovar H,Kriehuber E
Thu Dec 20 00:00:00 EST 2012
Periostin promotes chronic allergic inflammation in response to Th2 cytokines.
The Journal of clinical investigation
Masuoka M,Shiraishi H,Ohta S,Suzuki S,Arima K,Aoki S,Toda S,Inagaki N,Kurihara Y,Hayashida S,Takeuchi S,Koike K,Ono J,Noshiro H,Furue M,Conway SJ,Narisawa Y,Izuhara K
Sun Jul 01 00:00:00 EDT 2012
IL-15 protects NKT cells from inhibition by tumor-associated macrophages and enhances antimetastatic activity.
The Journal of clinical investigation
Liu D,Song L,Wei J,Courtney AN,Gao X,Marinova E,Guo L,Heczey A,Asgharzadeh S,Kim E,Dotti G,Metelitsa LS
Fri Jun 01 00:00:00 EDT 2012
Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4.
The Journal of experimental medicine
Junker Y,Zeissig S,Kim SJ,Barisani D,Wieser H,Leffler DA,Zevallos V,Libermann TA,Dillon S,Freitag TL,Kelly CP,Schuppan D
Mon Dec 17 00:00:00 EST 2012
Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis.
The Journal of experimental medicine
Bauer T,Zagórska A,Jurkin J,Yasmin N,Köffel R,Richter S,Gesslbauer B,Lemke G,Strobl H
Mon Oct 22 00:00:00 EDT 2012
High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.
The Journal of experimental medicine
Yang D,Postnikov YV,Li Y,Tewary P,de la Rosa G,Wei F,Klinman D,Gioannini T,Weiss JP,Furusawa T,Bustin M,Oppenheim JJ
Mon Jan 16 00:00:00 EST 2012
Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function.
Proceedings of the National Academy of Sciences of the United States of America
Zervantonakis IK,Hughes-Alford SK,Charest JL,Condeelis JS,Gertler FB,Kamm RD
Tue Aug 21 00:00:00 EDT 2012
C1q limits dendritic cell differentiation and activation by engaging LAIR-1.
Proceedings of the National Academy of Sciences of the United States of America
Son M,Santiago-Schwarz F,Al-Abed Y,Diamond B
Tue Nov 13 00:00:00 EST 2012
Dendritic and T cell response to influenza is normal in the patients with X-linked agammaglobulinemia.
Journal of clinical immunology
Liu Y,Wu Y,Lam KT,Lee PP,Tu W,Lau YL
Fri Jun 01 00:00:00 EDT 2012
Human papillomavirus type 8 interferes with a novel C/EBPβ-mediated mechanism of keratinocyte CCL20 chemokine expression and Langerhans cell migration.
PLoS pathogens
Sperling T,Ołdak M,Walch-Rückheim B,Wickenhauser C,Doorbar J,Pfister H,Malejczyk M,Majewski S,Keates AC,Smola S
Tue Jan 29 00:00:00 EST 2013
DENV inhibits type I IFN production in infected cells by cleaving human STING.
PLoS pathogens
Aguirre S,Maestre AM,Pagni S,Patel JR,Savage T,Gutman D,Maringer K,Bernal-Rubio D,Shabman RS,Simon V,Rodriguez-Madoz JR,Mulder LC,Barber GN,Fernandez-Sesma A
Thu Apr 04 00:00:00 EDT 2013
Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligand- and cell-dependent.
Immunology and cell biology
Hillyer P,Mane VP,Schramm LM,Puig M,Verthelyi D,Chen A,Zhao Z,Navarro MB,Kirschman KD,Bykadi S,Jubin RG,Rabin RL
Sat Sep 01 00:00:00 EDT 2012
Aberrant CD200/CD200R1 expression and function in systemic lupus erythematosus contributes to abnormal T-cell responsiveness and dendritic cell activity.
Arthritis research & therapy
Li Y,Zhao LD,Tong LS,Qian SN,Ren Y,Zhang L,Ding X,Chen Y,Wang YX,Zhang W,Zeng XF,Zhang FC,Tang FL,Zhang X,Ba DN,He W,Cao XT,Lipsky PE
Wed May 23 00:00:00 EDT 2012
Carboxypeptidase-M is regulated by lipids and CSFs in macrophages and dendritic cells and expressed selectively in tissue granulomas and foam cells.
Laboratory investigation; a journal of technical methods and pathology
Tsakiris I,Torocsik D,Gyongyosi A,Dozsa A,Szatmari I,Szanto A,Soos G,Nemes Z,Igali L,Marton I,Takats Z,Nagy L,Dezso B
Thu Mar 01 00:00:00 EST 2012
Availability of 25-hydroxyvitamin D(3) to APCs controls the balance between regulatory and inflammatory T cell responses.
Journal of immunology (Baltimore, Md. : 1950)
Jeffery LE,Wood AM,Qureshi OS,Hou TZ,Gardner D,Briggs Z,Kaur S,Raza K,Sansom DM
Sat Dec 01 00:00:00 EST 2012
Fetal-specific CD8+ cytotoxic T cell responses develop during normal human pregnancy and exhibit broad functional capacity.
Journal of immunology (Baltimore, Md. : 1950)
Lissauer D,Piper K,Goodyear O,Kilby MD,Moss PA
Sun Jul 15 00:00:00 EDT 2012
Semaphorin 4A exerts a proangiogenic effect by enhancing vascular endothelial growth factor-A expression in macrophages.
Journal of immunology (Baltimore, Md. : 1950)
Meda C,Molla F,De Pizzol M,Regano D,Maione F,Capano S,Locati M,Mantovani A,Latini R,Bussolino F,Giraudo E
Sun Apr 15 00:00:00 EDT 2012
An NKp30-based chimeric antigen receptor promotes T cell effector functions and antitumor efficacy in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Zhang T,Wu MR,Sentman CL
Sat Sep 01 00:00:00 EDT 2012
Neuropeptide signaling activates dendritic cell-mediated type 1 immune responses through neurokinin-2 receptor.
Journal of immunology (Baltimore, Md. : 1950)
Kitamura H,Kobayashi M,Wakita D,Nishimura T
Tue May 01 00:00:00 EDT 2012
Cyanovirin-N inhibits mannose-dependent Mycobacterium-C-type lectin interactions but does not protect against murine tuberculosis.
Journal of immunology (Baltimore, Md. : 1950)
Driessen NN,Boshoff HI,Maaskant JJ,Gilissen SA,Vink S,van der Sar AM,Vandenbroucke-Grauls CM,Bewley CA,Appelmelk BJ,Geurtsen J
Mon Oct 01 00:00:00 EDT 2012
Failure to induce IFN-β production during Staphylococcus aureus infection contributes to pathogenicity.
Journal of immunology (Baltimore, Md. : 1950)
Kaplan A,Ma J,Kyme P,Wolf AJ,Becker CA,Tseng CW,Liu GY,Underhill DM
Thu Nov 01 00:00:00 EDT 2012
Enhancing immunostimulatory function of human embryonic stem cell-derived dendritic cells by CD1d overexpression.
Journal of immunology (Baltimore, Md. : 1950)
Zeng J,Shahbazi M,Wu C,Toh HC,Wang S
Tue May 01 00:00:00 EDT 2012
Differential expression of neurotensin and specific receptors, NTSR1 and NTSR2, in normal and malignant human B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950)
Saada S,Marget P,Fauchais AL,Lise MC,Chemin G,Sindou P,Martel C,Delpy L,Vidal E,Jaccard A,Troutaud D,Lalloué F,Jauberteau MO
Sat Dec 01 00:00:00 EST 2012
Human γδ T lymphocytes are licensed for professional antigen presentation by interaction with opsonized target cells.
Journal of immunology (Baltimore, Md. : 1950)
Himoudi N,Morgenstern DA,Yan M,Vernay B,Saraiva L,Wu Y,Cohen CJ,Gustafsson K,Anderson J
Wed Feb 15 00:00:00 EST 2012
Regulation of the actin cytoskeleton by Rho kinase controls antigen presentation by CD1d.
Journal of immunology (Baltimore, Md. : 1950)
Gallo RM,Khan MA,Shi J,Kapur R,Wei L,Bailey JC,Liu J,Brutkiewicz RR
Wed Aug 15 00:00:00 EDT 2012
Elevated circulating interleukin-27 in patients with coronary artery disease is associated with dendritic cells, oxidized low-density lipoprotein, and severity of coronary artery stenosis.
Mediators of inflammation
Jin W,Zhao Y,Yan W,Cao L,Zhang W,Wang M,Zhang T,Fu Q,Li Z
Wed Nov 28 00:00:00 EST 2012
Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
Gene therapy
Silk KM,Silk JD,Ichiryu N,Davies TJ,Nolan KF,Leishman AJ,Carpenter L,Watt SM,Cerundolo V,Fairchild PJ
Mon Oct 01 00:00:00 EDT 2012
Gene expression profiling of dendritic cells in different physiological stages under Cordyceps sinensis treatment.
PloS one
Li CY,Chiang CS,Cheng WC,Wang SC,Cheng HT,Chen CR,Shu WY,Tsai ML,Hseu RS,Chang CW,Huang CY,Fang SH,Hsu IC
Fri Dec 07 00:00:00 EST 2012
Both lethal and edema toxins of Bacillus anthracis disrupt the human dendritic cell chemokine network.
PloS one
Cleret-Buhot A,Mathieu J,Tournier JN,Quesnel-Hellmann A
Thu Apr 25 00:00:00 EDT 2013
Slit2N/Robo1 inhibit HIV-gp120-induced migration and podosome formation in immature dendritic cells by sequestering LSP1 and WASp.
PloS one
Prasad A,Kuzontkoski PM,Shrivastava A,Zhu W,Li DY,Groopman JE
Mon May 06 00:00:00 EDT 2013
DCs pulsed with novel HLA-A2-restricted CTL epitopes against hepatitis C virus induced a broadly reactive anti-HCV-specific T lymphocyte response.
PloS one
Guo Z,Zhang H,Rao H,Jiang D,Cong X,Feng B,Wang J,Wei L,Chen H
Thu Nov 08 00:00:00 EST 2012
Divergent effects of mycobacterial cell wall glycolipids on maturation and function of human monocyte-derived dendritic cells.
PloS one
Mazurek J,Ignatowicz L,Kallenius G,Svenson SB,Pawlowski A,Hamasur B
Thu Jan 10 00:00:00 EST 2013
Type III interferons, IL-28 and IL-29, are increased in chronic HCV infection and induce myeloid dendritic cell-mediated FoxP3+ regulatory T cells.
PloS one
Dolganiuc A,Kodys K,Marshall C,Saha B,Zhang S,Bala S,Szabo G
Tue Apr 02 00:00:00 EDT 2013
Preformed CD40L is stored in Th1, Th2, Th17, and T follicular helper cells as well as CD4+ 8- thymocytes and invariant NKT cells but not in Treg cells.
PloS one
Koguchi Y,Buenafe AC,Thauland TJ,Gardell JL,Bivins-Smith ER,Jacoby DB,Slifka MK,Parker DC
Fri Jun 29 00:00:00 EDT 2012
Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).
PloS one
Suh HS,Choi N,Tarassishin L,Lee SC
Tue Aug 07 00:00:00 EDT 2012
TCR gene transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 epitopes as melanoma-specific immune targets.
Clinical & developmental immunology
Straetemans T,van Brakel M,van Steenbergen S,Broertjes M,Drexhage J,Hegmans J,Lambrecht BN,Lamers C,van Der Bruggen P,Coulie PG,Debets R
Fri Mar 01 00:00:00 EST 2013
Characterization of a mutated IgA2 antibody of the m(1) allotype against the epidermal growth factor receptor for the recruitment of monocytes and macrophages.
The Journal of biological chemistry
Lohse S,Brunke C,Derer S,Peipp M,Boross P,Kellner C,Beyer T,Dechant M,van der Winkel JG,Leusen JH,Valerius T
Fri Jul 20 00:00:00 EDT 2012
Increased IL-21 secretion by aged CD4+T cells is associated with prolonged STAT-4 activation and CMV seropositivity.
Aging
Agrawal A,Su H,Chen J,Osann K,Agrawal S,Gupta S
Sat Sep 01 00:00:00 EDT 2012
MHC class I-presented T cell epitopes identified by immunoproteomics analysis are targets for a cross reactive influenza-specific T cell response.
PloS one
Testa JS,Shetty V,Hafner J,Nickens Z,Kamal S,Sinnathamby G,Philip R
Wed Apr 24 00:00:00 EDT 2013
Differential expression of HIV-1 interfering factors in monocyte-derived macrophages stimulated with polarizing cytokines or interferons.
Scientific reports
Cobos Jiménez V,Booiman T,de Taeye SW,van Dort KA,Rits MA,Hamann J,Kootstra NA
Thu Mar 21 00:00:00 EDT 2013
Paracrine and transpresentation functions of IL-15 are mediated by diverse splice versions of IL-15Rα in human monocytes and dendritic cells.
The Journal of biological chemistry
Müller JR,Waldmann TA,Kruhlak MJ,Dubois S
Fri Nov 23 00:00:00 EST 2012
Rapamycin conditioning of dendritic cells differentiated from human ES cells promotes a tolerogenic phenotype.
Journal of biomedicine & biotechnology
Silk KM,Leishman AJ,Nishimoto KP,Reddy A,Fairchild PJ
Fri Sep 07 00:00:00 EDT 2012
Cloning and characterization of CD300d, a novel member of the human CD300 family of immune receptors.
The Journal of biological chemistry
Comas-Casellas E,Martínez-Barriocanal Á,Miró F,Ejarque-Ortiz A,Schwartz S,Martín M,Sayós J
Fri Mar 23 00:00:00 EDT 2012
IL-36γ/IL-1F9, an innate T-bet target in myeloid cells.
The Journal of biological chemistry
Bachmann M,Scheiermann P,Härdle L,Pfeilschifter J,Mühl H
Fri Dec 07 00:00:00 EST 2012
Neuroimmunoendocrine regulation of the prion protein in neutrophils.
The Journal of biological chemistry
Mariante RM,Nóbrega A,Martins RAP,Areal RB,Bellio M,Linden R
Fri Oct 12 00:00:00 EDT 2012
Identifying functional microRNAs in macrophages with polarized phenotypes.
The Journal of biological chemistry
Graff JW,Dickson AM,Clay G,McCaffrey AP,Wilson ME
Fri Jun 22 00:00:00 EDT 2012
Enhancement of myeloma development mediated though myeloma cell-Th2 cell interactions after microbial antigen presentation by myeloma cells and DCs.
Blood cancer journal
Tian F,Li J,Li Y,Luo S
Fri Jun 01 00:00:00 EDT 2012
Molecular mimics of the tumour antigen MUC1.
PloS one
James TC,Bond U
Thu Jun 20 00:00:00 EDT 2013
Innate and adaptive interferons suppress IL-1α and IL-1β production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection.
Immunity
Mayer-Barber KD,Andrade BB,Barber DL,Hieny S,Feng CG,Caspar P,Oland S,Gordon S,Sher A
Fri Dec 23 00:00:00 EST 2011
Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo.
Blood
Bosco MC,Pierobon D,Blengio F,Raggi F,Vanni C,Gattorno M,Eva A,Novelli F,Cappello P,Giovarelli M,Varesio L
Thu Mar 03 00:00:00 EST 2011
Monocytes from HTLV-1-infected patients are unable to fully mature into dendritic cells.
Blood
Nascimento CR,Lima MA,de Andrada Serpa MJ,Espindola O,Leite AC,Echevarria-Lima J
Thu Jan 13 00:00:00 EST 2011
IL-7 receptor expression identifies suicide gene-modified allospecific CD8+ T cells capable of self-renewal and differentiation into antileukemia effectors.
Blood
Bondanza A,Hambach L,Aghai Z,Nijmeijer B,Kaneko S,Mastaglio S,Radrizzani M,Fleischhauer K,Ciceri F,Bordignon C,Bonini C,Goulmy E
Thu Jun 16 00:00:00 EDT 2011
Natural killer cells expressing the KIR2DS1-activating receptor efficiently kill T-cell blasts and dendritic cells: implications in haploidentical HSCT.
Blood
Sivori S,Carlomagno S,Falco M,Romeo E,Moretta L,Moretta A
Thu Apr 21 00:00:00 EDT 2011
STAT6 signaling pathway activated by the cytokines IL-4 and IL-13 induces expression of the Epstein-Barr virus-encoded protein LMP-1 in absence of EBNA-2: implications for the type II EBV latent gene expression in Hodgkin lymphoma.
Blood
Kis LL,Gerasimcik N,Salamon D,Persson EK,Nagy N,Klein G,Severinson E,Klein E
Thu Jan 06 00:00:00 EST 2011
Cytoskeletal remodeling mediated by WASp in dendritic cells is necessary for normal immune synapse formation and T-cell priming.
Blood
Bouma G,Mendoza-Naranjo A,Blundell MP,de Falco E,Parsley KL,Burns SO,Thrasher AJ
Thu Sep 01 00:00:00 EDT 2011
Dendritic cells with lymphocyte-stimulating activity differentiate from human CD133 positive precursors.
Blood
Bonetti MI,Pieri L,Domenici L,Urbani S,Romano G,Aldinucci A,Ballerini C,Monici M,Saccardi R,Basile V,Bosi A,Romagnoli P
Thu Apr 14 00:00:00 EDT 2011
Paracrine inhibition of GM-CSF signaling by human cytomegalovirus in monocytes differentiating to dendritic cells.
Blood
Carlier J,Martin H,Mariamé B,Rauwel B,Mengelle C,Weclawiak H,Coaquette A,Vauchy C,Rohrlich P,Kamar N,Rostaing L,Herbein G,Davrinche C
Thu Dec 22 00:00:00 EST 2011
An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice.
The Journal of clinical investigation
Sindrilaru A,Peters T,Wieschalka S,Baican C,Baican A,Peter H,Hainzl A,Schatz S,Qi Y,Schlecht A,Weiss JM,Wlaschek M,Sunderkötter C,Scharffetter-Kochanek K
Tue Mar 01 00:00:00 EST 2011
Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection.
The Journal of experimental medicine
Séror C,Melki MT,Subra F,Raza SQ,Bras M,Saïdi H,Nardacci R,Voisin L,Paoletti A,Law F,Martins I,Amendola A,Abdul-Sater AA,Ciccosanti F,Delelis O,Niedergang F,Thierry S,Said-Sadier N,Lamaze C,Métivier D,Estaquier J,Fimia GM,Falasca L,Casetti R,Modjtahedi N,Kanellopoulos J,Mouscadet JF,Ojcius DM,Piacentini M,Gougeon ML,Kroemer G,Perfettini JL
Mon Aug 29 00:00:00 EDT 2011
In situ induction of dendritic cell-based T cell tolerance in humanized mice and nonhuman primates.
The Journal of experimental medicine
Jung KC,Park CG,Jeon YK,Park HJ,Ban YL,Min HS,Kim EJ,Kim JH,Kang BH,Park SP,Bae Y,Yoon IH,Kim YH,Lee JI,Kim JS,Shin JS,Yang J,Kim SJ,Rostlund E,Muller WA,Park SH
Mon Nov 21 00:00:00 EST 2011
Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells.
The Journal of experimental medicine
Saito M,Nagasawa M,Takada H,Hara T,Tsuchiya S,Agematsu K,Yamada M,Kawamura N,Ariga T,Tsuge I,Nonoyama S,Karasuyama H,Minegishi Y
Mon Feb 14 00:00:00 EST 2011
Hematopoietic differentiation and production of mature myeloid cells from human pluripotent stem cells.
Nature protocols
Choi KD,Vodyanik M,Slukvin II
Tue Mar 01 00:00:00 EST 2011
The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein.
PLoS pathogens
Varga ZT,Ramos I,Hai R,Schmolke M,García-Sastre A,Fernandez-Sesma A,Palese P
Wed Jun 01 00:00:00 EDT 2011
Effects of receptor binding specificity of avian influenza virus on the human innate immune response.
Journal of virology
Ramos I,Bernal-Rubio D,Durham N,Belicha-Villanueva A,Lowen AC,Steel J,Fernandez-Sesma A
Sun May 01 00:00:00 EDT 2011
Human gingiva-derived mesenchymal stromal cells attenuate contact hypersensitivity via prostaglandin E2-dependent mechanisms.
Stem cells (Dayton, Ohio)
Su WR,Zhang QZ,Shi SH,Nguyen AL,Le AD
Tue Nov 01 00:00:00 EDT 2011
Human TCR transgenic Bet v 1-specific Th1 cells suppress the effector function of Bet v 1-specific Th2 cells.
Journal of immunology (Baltimore, Md. : 1950)
Neunkirchner A,Leb-Reichl VM,Schmetterer KG,Mutschlechner S,Kueng HJ,Haiderer D,Schuch K,Wallner M,Jahn-Schmid B,Bohle B,Pickl WF
Sat Oct 15 00:00:00 EDT 2011
Phagocytosis, a potential mechanism for myeloid-derived suppressor cell regulation of CD8+ T cell function mediated through programmed cell death-1 and programmed cell death-1 ligand interaction.
Journal of immunology (Baltimore, Md. : 1950)
Kim YJ,Park SJ,Broxmeyer HE
Thu Sep 01 00:00:00 EDT 2011
Enhanced cancer immunotherapy using STAT3-depleted dendritic cells with high Th1-inducing ability and resistance to cancer cell-derived inhibitory factors.
Journal of immunology (Baltimore, Md. : 1950)
Iwata-Kajihara T,Sumimoto H,Kawamura N,Ueda R,Takahashi T,Mizuguchi H,Miyagishi M,Takeda K,Kawakami Y
Fri Jul 01 00:00:00 EDT 2011
Macrophages at the fetal-maternal interface express markers of alternative activation and are induced by M-CSF and IL-10.
Journal of immunology (Baltimore, Md. : 1950)
Svensson J,Jenmalm MC,Matussek A,Geffers R,Berg G,Ernerudh J
Sat Oct 01 00:00:00 EDT 2011
IFN-β mediates suppression of IL-12p40 in human dendritic cells following infection with virulent Francisella tularensis.
Journal of immunology (Baltimore, Md. : 1950)
Bauler TJ,Chase JC,Bosio CM
Mon Aug 15 00:00:00 EDT 2011
A live imaging cell motility screen identifies prostaglandin E2 as a T cell stop signal antagonist.
Journal of immunology (Baltimore, Md. : 1950)
Wiemer AJ,Hegde S,Gumperz JE,Huttenlocher A
Sat Oct 01 00:00:00 EDT 2011
Common lymphatic endothelial and vascular endothelial receptor-1 mediates the transmigration of regulatory T cells across human hepatic sinusoidal endothelium.
Journal of immunology (Baltimore, Md. : 1950)
Shetty S,Weston CJ,Oo YH,Westerlund N,Stamataki Z,Youster J,Hubscher SG,Salmi M,Jalkanen S,Lalor PF,Adams DH
Fri Apr 01 00:00:00 EDT 2011
Peroxisome proliferator-activated receptor γ-regulated cathepsin D is required for lipid antigen presentation by dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Nakken B,Varga T,Szatmari I,Szeles L,Gyongyosi A,Illarionov PA,Dezso B,Gogolak P,Rajnavolgyi E,Nagy L
Fri Jul 01 00:00:00 EDT 2011
Provision of continuous maturation signaling to dendritic cells by RIG-I-stimulating cytosolic RNA synthesis of Sendai virus.
Journal of immunology (Baltimore, Md. : 1950)
Okano S,Yonemitsu Y,Shirabe K,Kakeji Y,Maehara Y,Harada M,Yoshikai Y,Inoue M,Hasegawa M,Sueishi K
Tue Feb 01 00:00:00 EST 2011
HIV-mediated phosphatidylinositol 3-kinase/serine-threonine kinase activation in APCs leads to programmed death-1 ligand upregulation and suppression of HIV-specific CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950)
Muthumani K,Shedlock DJ,Choo DK,Fagone P,Kawalekar OU,Goodman J,Bian CB,Ramanathan AA,Atman P,Tebas P,Chattergoon MA,Choo AY,Weiner DB
Thu Sep 15 00:00:00 EDT 2011
Antibody-mediated coengagement of FcγRIIb and B cell receptor complex suppresses humoral immunity in systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950)
Horton HM,Chu SY,Ortiz EC,Pong E,Cemerski S,Leung IW,Jacob N,Zalevsky J,Desjarlais JR,Stohl W,Szymkowski DE
Fri Apr 01 00:00:00 EDT 2011
Thymic stromal lymphopoietin is produced by dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Kashyap M,Rochman Y,Spolski R,Samsel L,Leonard WJ
Mon Aug 01 00:00:00 EDT 2011
Platelet-activating factor induces Th17 cell differentiation.
Mediators of inflammation
Drolet AM,Thivierge M,Turcotte S,Hanna D,Maynard B,Stankovà J,Rola-Pleszczynski M
Tue May 15 00:00:00 EDT 2012
The zymogen granule protein 2 (GP2) binds to scavenger receptor expressed on endothelial cells I (SREC-I).
Cellular immunology
Hölzl MA,Hofer J,Kovarik JJ,Roggenbuck D,Reinhold D,Goihl A,Gärtner M,Steinberger P,Zlabinger GJ
Mon Apr 18 00:00:00 EDT 2011
Successive influenza virus infection and Streptococcus pneumoniae stimulation alter human dendritic cell function.
BMC infectious diseases
Wu Y,Mao H,Ling MT,Chow KH,Ho PL,Tu W,Lau YL
Wed Jul 20 00:00:00 EDT 2011
Lipoglycans contribute to innate immune detection of mycobacteria.
PloS one
Krishna S,Ray A,Dubey SK,Larrouy-Maumus G,Chalut C,Castanier R,Noguera A,Gilleron M,Puzo G,Vercellone A,Nampoothiri KM,Nigou J
Fri Jul 20 00:00:00 EDT 2012
Mature autologous dendritic cell vaccines in advanced non-small cell lung cancer: a phase I pilot study.
Journal of experimental & clinical cancer research : CR
Perroud MW,Honma HN,Barbeiro AS,Gilli SC,Almeida MT,Vassallo J,Saad ST,Zambon L
Fri Jun 17 00:00:00 EDT 2011
Efficient activation of T cells by human monocyte-derived dendritic cells (HMDCs) pulsed with Coxiella burnetii outer membrane protein Com1 but not by HspB-pulsed HMDCs.
BMC immunology
Wang Y,Xiong X,Wu D,Wang X,Wen B
Sat Sep 03 00:00:00 EDT 2011
Mannan-binding lectin regulates dendritic cell maturation and cytokine production induced by lipopolysaccharide.
BMC immunology
Wang M,Zhang Y,Chen Y,Zhang L,Lu X,Chen Z
Sat Jan 01 00:00:00 EST 2011
Poly I: C-activated dendritic cells that were generated in CellGro for use in cancer immunotherapy trials.
Journal of translational medicine
Fučíková J,Rožková D,Ulčová H,Budinský V,Sochorová K,Pokorná K,Bartůňková J,Špíšek R
Fri Dec 30 00:00:00 EST 2011
IL-4 and IL-13 exposure during mucociliary differentiation of bronchial epithelial cells increases antimicrobial activity and expression of antimicrobial peptides.
Respiratory research
Zuyderduyn S,Ninaber DK,Schrumpf JA,van Sterkenburg MA,Verhoosel RM,Prins FA,van Wetering S,Rabe KF,Hiemstra PS
Mon May 02 00:00:00 EDT 2011
TNF-alpha induces macroautophagy and regulates MHC class II expression in human skeletal muscle cells.
The Journal of biological chemistry
Keller CW,Fokken C,Turville SG,Lünemann A,Schmidt J,Münz C,Lünemann JD
Fri Feb 04 00:00:00 EST 2011
Optimizing parameters for clinical-scale production of high IL-12 secreting dendritic cells pulsed with oxidized whole tumor cell lysate.
Journal of translational medicine
Chiang CL,Maier DA,Kandalaft LE,Brennan AL,Lanitis E,Ye Q,Levine BL,Czerniecki BJ,Powell DJ,Coukos G
Mon Nov 14 00:00:00 EST 2011
Enhanced presentation of MHC class Ia, Ib and class II-restricted peptides encapsulated in biodegradable nanoparticles: a promising strategy for tumor immunotherapy.
Journal of translational medicine
Ma W,Smith T,Bogin V,Zhang Y,Ozkan C,Ozkan M,Hayden M,Schroter S,Carrier E,Messmer D,Kumar V,Minev B
Thu Mar 31 00:00:00 EDT 2011
Modulation of human immune responses by bovine interleukin-10.
PloS one
den Hartog G,Savelkoul HF,Schoemaker R,Tijhaar E,Westphal AH,de Ruiter T,van de Weg-Schrijver E,van Neerven RJ
Fri Mar 25 00:00:00 EDT 2011
Modulation of human immune responses by bovine interleukin-10.
PloS one
den Hartog G,Savelkoul HF,Schoemaker R,Tijhaar E,Westphal AH,de Ruiter T,van de Weg-Schrijver E,van Neerven RJ
Fri Mar 25 00:00:00 EDT 2011
Role of IL-1 beta in the development of human T(H)17 cells: lesson from NLPR3 mutated patients.
PloS one
Lasigliè D,Traggiai E,Federici S,Alessio M,Buoncompagni A,Accogli A,Chiesa S,Penco F,Martini A,Gattorno M
Thu Sep 29 00:00:00 EDT 2011
Broad antiviral activity of carbohydrate-binding agents against the four serotypes of dengue virus in monocyte-derived dendritic cells.
PloS one
Alen MM,De Burghgraeve T,Kaptein SJ,Balzarini J,Neyts J,Schols D
Thu Dec 01 00:00:00 EST 2011
Alpha-defensins 1-3 release by dendritic cells is reduced by estrogen.
Reproductive biology and endocrinology : RB&E
Escribese MM,Rodríguez-García M,Sperling R,Engel SM,Gallart T,Moran TM
Tue Aug 23 00:00:00 EDT 2011
Bleomycin hydrolase is regulated biphasically in a differentiation- and cytokine-dependent manner: relevance to atopic dermatitis.
The Journal of biological chemistry
Kamata Y,Yamamoto M,Kawakami F,Tsuboi R,Takeda A,Ishihara K,Hibino T
Fri Mar 11 00:00:00 EST 2011
PTB-associated splicing factor (PSF) functions as a repressor of STAT6-mediated Ig epsilon gene transcription by recruitment of HDAC1.
The Journal of biological chemistry
Dong L,Zhang X,Fu X,Zhang X,Gao X,Zhu M,Wang X,Yang Z,Jensen ON,Saarikettu J,Yao Z,Silvennoinen O,Yang J
Fri Feb 04 00:00:00 EST 2011
The therapeutic effect of cytokine-induced killer cells on pancreatic cancer enhanced by dendritic cells pulsed with K-ras mutant peptide.
Clinical & developmental immunology
Tan G,Zhang X,Feng H,Luo H,Wang Z
Wed Jun 06 00:00:00 EDT 2012
KIR and HLA-C interactions promote differential dendritic cell maturation and is a major determinant of graft failure following kidney transplantation.
PloS one
Hanvesakul R,Kubal C,Moore J,Neil D,Cook M,Ball S,Briggs D,Moss P,Cockwell P
Fri Dec 23 00:00:00 EST 2011
Deactivation of STAT6 through serine 707 phosphorylation by JNK.
The Journal of biological chemistry
Shirakawa T,Kawazoe Y,Tsujikawa T,Jung D,Sato S,Uesugi M
Fri Feb 04 00:00:00 EST 2011
Production of lentiviral vectors with enhanced efficiency to target dendritic cells by attenuating mannosidase activity of mammalian cells.
Journal of biological engineering
Tai A,Froelich S,Joo KI,Wang P
Fri Jan 28 00:00:00 EST 2011
Cytokine-based high log-scale expansion of functional human dendritic cells from cord-blood CD34-positive cells.
Scientific reports
Harada Y,Okada-Nakanishi Y,Ueda Y,Tsujitani S,Saito S,Fuji-Ogawa T,Iida A,Hasegawa M,Ichikawa T,Yonemitsu Y
Tue Sep 10 00:00:00 EDT 2013
Comparing the immunosuppressive potency of naïve marrow stromal cells and Notch-transfected marrow stromal cells.
Journal of neuroinflammation
Dao MA,Tate CC,Aizman I,McGrogan M,Case CC
Fri Oct 07 00:00:00 EDT 2011
MicroRNA expression profiles of human blood monocyte-derived dendritic cells and macrophages reveal miR-511 as putative positive regulator of Toll-like receptor 4.
The Journal of biological chemistry
Tserel L,Runnel T,Kisand K,Pihlap M,Bakhoff L,Kolde R,Peterson H,Vilo J,Peterson P,Rebane A
Fri Jul 29 00:00:00 EDT 2011
IL-7 promotes CD95-induced apoptosis in B cells via the IFN-γ/STAT1 pathway.
PloS one
Sammicheli S,Dang VP,Ruffin N,Pham HT,Lantto R,Vivar N,Chiodi F,Rethi B
Mon Aug 27 00:00:00 EDT 2012
Day-4 myeloid dendritic cells pulsed with whole tumor lysate are highly immunogenic and elicit potent anti-tumor responses.
PloS one
Chiang CL,Hagemann AR,Leskowitz R,Mick R,Garrabrant T,Czerniecki BJ,Kandalaft LE,Powell DJ,Coukos G
Mon Aug 27 00:00:00 EDT 2012
Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation.
The Journal of biological chemistry
Watanabe A,Tatematsu M,Saeki K,Shibata S,Shime H,Yoshimura A,Obuse C,Seya T,Matsumoto M
Fri Mar 25 00:00:00 EDT 2011
GATA3 expression is decreased in psoriasis and during epidermal regeneration; induction by narrow-band UVB and IL-4.
PloS one
Rácz E,Kurek D,Kant M,Baerveldt EM,Florencia E,Mourits S,de Ridder D,Laman JD,van der Fits L,Prens EP
Mon Sep 12 00:00:00 EDT 2011
High and low molecular weight hyaluronic acid differentially regulate human fibrocyte differentiation.
PloS one
Maharjan AS,Pilling D,Gomer RH
Fri Feb 17 00:00:00 EST 2012
Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia.
Nature
Cavazzana-Calvo M,Payen E,Negre O,Wang G,Hehir K,Fusil F,Down J,Denaro M,Brady T,Westerman K,Cavallesco R,Gillet-Legrand B,Caccavelli L,Sgarra R,Maouche-Chrétien L,Bernaudin F,Girot R,Dorazio R,Mulder GJ,Polack A,Bank A,Soulier J,Larghero J,Kabbara N,Dalle B,Gourmel B,Socie G,Chrétien S,Cartier N,Aubourg P,Fischer A,Cornetta K,Galacteros F,Beuzard Y,Gluckman E,Bushman F,Hacein-Bey-Abina S,Leboulch P
Thu Sep 16 00:00:00 EDT 2010
STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells.
Immunity
Szanto A,Balint BL,Nagy ZS,Barta E,Dezso B,Pap A,Szeles L,Poliska S,Oros M,Evans RM,Barak Y,Schwabe J,Nagy L
Wed Nov 24 00:00:00 EST 2010
IRF5 is required for late-phase TNF secretion by human dendritic cells.
Blood
Krausgruber T,Saliba D,Ryzhakov G,Lanfrancotti A,Blazek K,Udalova IA
Thu Jun 03 00:00:00 EDT 2010
Human fibroblasts support the expansion of IL-17-producing T cells via up-regulation of IL-23 production by dendritic cells.
Blood
Schirmer C,Klein C,von Bergen M,Simon JC,Saalbach A
Thu Sep 09 00:00:00 EDT 2010
Requirement of the human T-cell leukemia virus p12 and p30 products for infectivity of human dendritic cells and macaques but not rabbits.
Blood
Valeri VW,Hryniewicz A,Andresen V,Jones K,Fenizia C,Bialuk I,Chung HK,Fukumoto R,Parks RW,Ferrari MG,Nicot C,Cecchinato V,Ruscetti F,Franchini G
Thu Nov 11 00:00:00 EST 2010
Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.
Blood
Tewary P,Yang D,de la Rosa G,Li Y,Finn MW,Krensky AM,Clayberger C,Oppenheim JJ
Thu Nov 04 00:00:00 EDT 2010
Beyond the enhanceosome: cluster of novel κB sites downstream of the human IFN-β gene is essential for lipopolysaccharide-induced gene activation.
Blood
Goh FG,Thomson SJ,Krausgruber T,Lanfrancotti A,Copley RR,Udalova IA
Thu Dec 16 00:00:00 EST 2010
Alterations in the antigen processing-presenting machinery of transformed plasma cells are associated with reduced recognition by CD8+ T cells and characterize the progression of MGUS to multiple myeloma.
Blood
Racanelli V,Leone P,Frassanito MA,Brunetti C,Perosa F,Ferrone S,Dammacco F
Thu Feb 11 00:00:00 EST 2010
Thymic stromal lymphopoietin from trophoblasts induces dendritic cell-mediated regulatory TH2 bias in the decidua during early gestation in humans.
Blood
Guo PF,Du MR,Wu HX,Lin Y,Jin LP,Li DJ
Thu Sep 23 00:00:00 EDT 2010
ATP secreted by endothelial cells blocks CX₃CL 1-elicited natural killer cell chemotaxis and cytotoxicity via P2Y₁₁ receptor activation.
Blood
Gorini S,Callegari G,Romagnoli G,Mammi C,Mavilio D,Rosano G,Fini M,Di Virgilio F,Gulinelli S,Falzoni S,Cavani A,Ferrari D,la Sala A
Thu Nov 25 00:00:00 EST 2010
Vitamin D3 attenuates Th2 responses to Aspergillus fumigatus mounted by CD4+ T cells from cystic fibrosis patients with allergic bronchopulmonary aspergillosis.
The Journal of clinical investigation
Kreindler JL,Steele C,Nguyen N,Chan YR,Pilewski JM,Alcorn JF,Vyas YM,Aujla SJ,Finelli P,Blanchard M,Zeigler SF,Logar A,Hartigan E,Kurs-Lasky M,Rockette H,Ray A,Kolls JK
Wed Sep 01 00:00:00 EDT 2010
Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90.
The Journal of experimental medicine
Orthwein A,Patenaude AM,Affar el B,Lamarre A,Young JC,Di Noia JM
Mon Nov 22 00:00:00 EST 2010
Thymic stromal lymphopoietin-mediated STAT5 phosphorylation via kinases JAK1 and JAK2 reveals a key difference from IL-7-induced signaling.
Proceedings of the National Academy of Sciences of the United States of America
Rochman Y,Kashyap M,Robinson GW,Sakamoto K,Gomez-Rodriguez J,Wagner KU,Leonard WJ
Tue Nov 09 00:00:00 EST 2010
T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism.
Proceedings of the National Academy of Sciences of the United States of America
Edfeldt K,Liu PT,Chun R,Fabri M,Schenk M,Wheelwright M,Keegan C,Krutzik SR,Adams JS,Hewison M,Modlin RL
Tue Dec 28 00:00:00 EST 2010
Prolonged antigen survival and cytosolic export in cross-presenting human gammadelta T cells.
Proceedings of the National Academy of Sciences of the United States of America
Meuter S,Eberl M,Moser B
Tue May 11 00:00:00 EDT 2010
IL-21 imposes a type II EBV gene expression on type III and type I B cells by the repression of C- and activation of LMP-1-promoter.
Proceedings of the National Academy of Sciences of the United States of America
Kis LL,Salamon D,Persson EK,Nagy N,Scheeren FA,Spits H,Klein G,Klein E
Tue Jan 12 00:00:00 EST 2010
Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection.
Proceedings of the National Academy of Sciences of the United States of America
Takahashi K,Asabe S,Wieland S,Garaigorta U,Gastaminza P,Isogawa M,Chisari FV
Tue Apr 20 00:00:00 EDT 2010
Oxidation of cell surface thiol groups by contact sensitizers triggers the maturation of dendritic cells.
The Journal of investigative dermatology
Kagatani S,Sasaki Y,Hirota M,Mizuashi M,Suzuki M,Ohtani T,Itagaki H,Aiba S
Fri Jan 01 00:00:00 EST 2010
Escape of HIV-1-infected dendritic cells from TRAIL-mediated NK cell cytotoxicity during NK-DC cross-talk--a pivotal role of HMGB1.
PLoS pathogens
Melki MT,Saïdi H,Dufour A,Olivo-Marin JC,Gougeon ML
Thu Apr 15 00:00:00 EDT 2010
Mycobacterium leprae phenolglycolipid-1 expressed by engineered M. bovis BCG modulates early interaction with human phagocytes.
PLoS pathogens
Tabouret G,Astarie-Dequeker C,Demangel C,Malaga W,Constant P,Ray A,Honoré N,Bello NF,Perez E,Daffé M,Guilhot C
Thu Oct 21 00:00:00 EDT 2010
A novel pseudopodial component of the dendritic cell anti-fungal response: the fungipod.
PLoS pathogens
Neumann AK,Jacobson K
Fri Feb 12 00:00:00 EST 2010
PPARgamma and LXR signaling inhibit dendritic cell-mediated HIV-1 capture and trans-infection.
PLoS pathogens
Hanley TM,Blay Puryear W,Gummuluru S,Viglianti GA
Thu Jul 01 00:00:00 EDT 2010
Human gingiva-derived mesenchymal stem cells elicit polarization of m2 macrophages and enhance cutaneous wound healing.
Stem cells (Dayton, Ohio)
Zhang QZ,Su WR,Shi SH,Wilder-Smith P,Xiang AP,Wong A,Nguyen AL,Kwon CW,Le AD
Fri Oct 01 00:00:00 EDT 2010
Drug antigenicity, immunogenicity, and costimulatory signaling: evidence for formation of a functional antigen through immune cell metabolism.
Journal of immunology (Baltimore, Md. : 1950)
Elsheikh A,Lavergne SN,Castrejon JL,Farrell J,Wang H,Sathish J,Pichler WJ,Park BK,Naisbitt DJ
Wed Dec 01 00:00:00 EST 2010
Diesel exhaust particle-treated human bronchial epithelial cells upregulate Jagged-1 and OX40 ligand in myeloid dendritic cells via thymic stromal lymphopoietin.
Journal of immunology (Baltimore, Md. : 1950)
Bleck B,Tse DB,Gordon T,Ahsan MR,Reibman J
Wed Dec 01 00:00:00 EST 2010
A common polymorphism in the caspase recruitment domain of RIG-I modifies the innate immune response of human dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Hu J,Nistal-Villán E,Voho A,Ganee A,Kumar M,Ding Y,García-Sastre A,Wetmur JG
Thu Jul 01 00:00:00 EDT 2010
Escherichia coli K1 promotes the ligation of CD47 with thrombospondin-1 to prevent the maturation of dendritic cells in the pathogenesis of neonatal meningitis.
Journal of immunology (Baltimore, Md. : 1950)
Mittal R,Gonzalez-Gomez I,Prasadarao NV
Wed Sep 01 00:00:00 EDT 2010
A versatile role of mammalian target of rapamycin in human dendritic cell function and differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Haidinger M,Poglitsch M,Geyeregger R,Kasturi S,Zeyda M,Zlabinger GJ,Pulendran B,Hörl WH,Säemann MD,Weichhart T
Fri Oct 01 00:00:00 EDT 2010
Phagocytosis of apoptotic cells by neutrophil granulocytes: diminished proinflammatory neutrophil functions in the presence of apoptotic cells.
Journal of immunology (Baltimore, Md. : 1950)
Esmann L,Idel C,Sarkar A,Hellberg L,Behnen M,Möller S,van Zandbergen G,Klinger M,Köhl J,Bussmeyer U,Solbach W,Laskay T
Fri Jan 01 00:00:00 EST 2010
Activation of liver X receptor sensitizes human dendritic cells to inflammatory stimuli.
Journal of immunology (Baltimore, Md. : 1950)
Töröcsik D,Baráth M,Benko S,Széles L,Dezso B,Póliska S,Hegyi Z,Homolya L,Szatmári I,Lányi A,Nagy L
Sat May 15 00:00:00 EDT 2010
Antiviral response dictated by choreographed cascade of transcription factors.
Journal of immunology (Baltimore, Md. : 1950)
Zaslavsky E,Hershberg U,Seto J,Pham AM,Marquez S,Duke JL,Wetmur JG,Tenoever BR,Sealfon SC,Kleinstein SH
Mon Mar 15 00:00:00 EDT 2010
IL-4 and TGF-beta 1 counterbalance one another while regulating mast cell homeostasis.
Journal of immunology (Baltimore, Md. : 1950)
Macey MR,Sturgill JL,Morales JK,Falanga YT,Morales J,Norton SK,Yerram N,Shim H,Fernando J,Gifillan AM,Gomez G,Schwartz L,Oskeritzian C,Spiegel S,Conrad D,Ryan JJ
Sat May 01 00:00:00 EDT 2010
Inhibition of NF-κB signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE.
Journal of immunology (Baltimore, Md. : 1950)
Vossenkämper A,Marchès O,Fairclough PD,Warnes G,Stagg AJ,Lindsay JO,Evans PC,Luong le A,Croft NM,Naik S,Frankel G,MacDonald TT
Fri Oct 01 00:00:00 EDT 2010
Tumor-conditioned macrophages secrete migration-stimulating factor: a new marker for M2-polarization, influencing tumor cell motility.
Journal of immunology (Baltimore, Md. : 1950)
Solinas G,Schiarea S,Liguori M,Fabbri M,Pesce S,Zammataro L,Pasqualini F,Nebuloni M,Chiabrando C,Mantovani A,Allavena P
Thu Jul 01 00:00:00 EDT 2010
Pollen-induced oxidative stress influences both innate and adaptive immune responses via altering dendritic cell functions.
Journal of immunology (Baltimore, Md. : 1950)
Csillag A,Boldogh I,Pazmandi K,Magyarics Z,Gogolak P,Sur S,Rajnavolgyi E,Bacsi A
Mon Mar 01 00:00:00 EST 2010
Unique epitopes on C epsilon mX in IgE-B cell receptors are potentially applicable for targeting IgE-committed B cells.
Journal of immunology (Baltimore, Md. : 1950)
Chen JB,Wu PC,Hung AF,Chu CY,Tsai TF,Yu HM,Chang HY,Chang TW
Mon Feb 15 00:00:00 EST 2010
Enhanced activation of T lymphocytes by urease-deficient recombinant bacillus Calmette-Guérin producing heat shock protein 70-major membrane protein-II fusion protein.
Journal of immunology (Baltimore, Md. : 1950)
Mukai T,Maeda Y,Tamura T,Matsuoka M,Tsukamoto Y,Makino M
Mon Nov 15 00:00:00 EST 2010
Transcription factor E2F1 suppresses dendritic cell maturation.
Journal of immunology (Baltimore, Md. : 1950)
Fang F,Wang Y,Li R,Zhao Y,Guo Y,Jiang M,Sun J,Ma Y,Ren Z,Tian Z,Wei F,Yang D,Xiao W
Tue Jun 01 00:00:00 EDT 2010
Early recycling compartment trafficking of CD1a is essential for its intersection and presentation of lipid antigens.
Journal of immunology (Baltimore, Md. : 1950)
Cernadas M,Cavallari M,Watts G,Mori L,De Libero G,Brenner MB
Mon Feb 01 00:00:00 EST 2010
miR-146a is differentially expressed by myeloid dendritic cell subsets and desensitizes cells to TLR2-dependent activation.
Journal of immunology (Baltimore, Md. : 1950)
Jurkin J,Schichl YM,Koeffel R,Bauer T,Richter S,Konradi S,Gesslbauer B,Strobl H
Sat May 01 00:00:00 EDT 2010
Expanded numbers of circulating myeloid dendritic cells in patent human filarial infection reflect lower CCR1 expression.
Journal of immunology (Baltimore, Md. : 1950)
Semnani RT,Mahapatra L,Dembele B,Konate S,Metenou S,Dolo H,Coulibaly ME,Soumaoro L,Coulibaly SY,Sanogo D,Seriba Doumbia S,Diallo AA,Traoré SF,Klion A,Nutman TB,Mahanty S
Mon Nov 15 00:00:00 EST 2010
A threonine-based targeting signal in the human CD1d cytoplasmic tail controls its functional expression.
Journal of immunology (Baltimore, Md. : 1950)
Liu J,Shaji D,Cho S,Du W,Gervay-Hague J,Brutkiewicz RR
Sat May 01 00:00:00 EDT 2010
Age-associated epigenetic modifications in human DNA increase its immunogenicity.
Aging
Agrawal A,Tay J,Yang GE,Agrawal S,Gupta S
Sat Mar 20 00:00:00 EDT 2010
Immunostimulatory properties of dendritic cells after Leishmania donovani infection using an in vitro model of liver microenvironment.
PLoS neglected tropical diseases
Donaghy L,Cabillic F,Corlu A,Rostan O,Toutirais O,Guguen-Guillouzo C,Guiguen C,Gangneux JP
Tue Jun 08 00:00:00 EDT 2010
Dendritic cell activation prevents MHC class II ubiquitination and promotes MHC class II survival regardless of the activation stimulus.
The Journal of biological chemistry
Walseng E,Furuta K,Goldszmid RS,Weih KA,Sher A,Roche PA
Fri Dec 31 00:00:00 EST 2010
A conserved E7-derived cytotoxic T lymphocyte epitope expressed on human papillomavirus 16-transformed HLA-A2+ epithelial cancers.
The Journal of biological chemistry
Riemer AB,Keskin DB,Zhang G,Handley M,Anderson KS,Brusic V,Reinhold B,Reinherz EL
Fri Sep 17 00:00:00 EDT 2010
Selective expansion of chimeric antigen receptor-targeted T-cells with potent effector function using interleukin-4.
The Journal of biological chemistry
Wilkie S,Burbridge SE,Chiapero-Stanke L,Pereira AC,Cleary S,van der Stegen SJ,Spicer JF,Davies DM,Maher J
Fri Aug 13 00:00:00 EDT 2010
The impact of vitamin D on dendritic cell function in patients with systemic lupus erythematosus.
PloS one
Ben-Zvi I,Aranow C,Mackay M,Stanevsky A,Kamen DL,Marinescu LM,Collins CE,Gilkeson GS,Diamond B,Hardin JA
Tue Feb 16 00:00:00 EST 2010
Uterine epithelial cell regulation of DC-SIGN expression inhibits transmitted/founder HIV-1 trans infection by immature dendritic cells.
PloS one
Ochiel DO,Ochsenbauer C,Kappes JC,Ghosh M,Fahey JV,Wira CR
Tue Dec 14 00:00:00 EST 2010
Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response.
The Journal of biological chemistry
Mao AP,Li S,Zhong B,Li Y,Yan J,Li Q,Teng C,Shu HB
Fri Mar 26 00:00:00 EDT 2010
Human dendritic cells activated via dectin-1 are efficient at priming Th17, cytotoxic CD8 T and B cell responses.
PloS one
Agrawal S,Gupta S,Agrawal A
Mon Oct 18 00:00:00 EDT 2010
miR-17-92 expression in differentiated T cells - implications for cancer immunotherapy.
Journal of translational medicine
Sasaki K,Kohanbash G,Hoji A,Ueda R,McDonald HA,Reinhart TA,Martinson J,Lotze MT,Marincola FM,Wang E,Fujita M,Okada H
Thu Feb 18 00:00:00 EST 2010
Differential effects of Paclitaxel on dendritic cell function.
BMC immunology
John J,Ismail M,Riley C,Askham J,Morgan R,Melcher A,Pandha H
Fri Mar 19 00:00:00 EDT 2010
Differential induction of inflammatory cytokines by dendritic cells treated with novel TLR-agonist and cytokine based cocktails: targeting dendritic cells in autoimmunity.
Journal of inflammation (London, England)
Jensen SS,Gad M
Tue Jul 27 00:00:00 EDT 2010
Azadirachtin interacts with the tumor necrosis factor (TNF) binding domain of its receptors and inhibits TNF-induced biological responses.
The Journal of biological chemistry
Thoh M,Kumar P,Nagarajaram HA,Manna SK
Fri Feb 19 00:00:00 EST 2010
Association of IL-4RA single nucleotide polymorphisms, HLA-DR and HLA-DQ in children with Alternaria-sensitive moderate-severe asthma.
Clinical and molecular allergy : CMA
Knutsen AP,Vijay HM,Kariuki B,Santiago LA,Graff R,Wofford JD,Shah MR
Thu Mar 18 00:00:00 EDT 2010
A pilot clinical trial testing mutant von Hippel-Lindau peptide as a novel immune therapy in metastatic renal cell carcinoma.
Journal of translational medicine
Rahma OE,Ashtar E,Ibrahim R,Toubaji A,Gause B,Herrin VE,Linehan WM,Steinberg SM,Grollman F,Grimes G,Bernstein SA,Berzofsky JA,Khleif SN
Thu Jan 28 00:00:00 EST 2010
The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA.
Immunity
Zhong B,Zhang L,Lei C,Li Y,Mao AP,Yang Y,Wang YY,Zhang XL,Shu HB
Fri Mar 20 00:00:00 EDT 2009
Impaired development of human Th1 cells in patients with deficient expression of STAT4.
Blood
Chang HC,Han L,Goswami R,Nguyen ET,Pelloso D,Robertson MJ,Kaplan MH
Thu Jun 04 00:00:00 EDT 2009
MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2.
Blood
Spaggiari GM,Abdelrazik H,Becchetti F,Moretta L
Thu Jun 25 00:00:00 EDT 2009
Identification of proapoptotic Bim as a tumor suppressor in neoplastic mast cells: role of KIT D816V and effects of various targeted drugs.
Blood
Aichberger KJ,Gleixner KV,Mirkina I,Cerny-Reiterer S,Peter B,Ferenc V,Kneidinger M,Baumgartner C,Mayerhofer M,Gruze A,Pickl WF,Sillaber C,Valent P
Thu Dec 17 00:00:00 EST 2009
Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes.
Blood
Van den Bossche J,Bogaert P,van Hengel J,Guérin CJ,Berx G,Movahedi K,Van den Bergh R,Pereira-Fernandes A,Geuns JM,Pircher H,Dorny P,Grooten J,De Baetselier P,Van Ginderachter JA
Thu Nov 19 00:00:00 EST 2009
HIV-1 gp120-induced migration of dendritic cells is regulated by a novel kinase cascade involving Pyk2, p38 MAP kinase, and LSP1.
Blood
Anand AR,Prasad A,Bradley RR,Deol YS,Nagaraja T,Ren X,Terwilliger EF,Ganju RK
Thu Oct 22 00:00:00 EDT 2009
High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia.
Blood
Herling M,Patel KA,Weit N,Lilienthal N,Hallek M,Keating MJ,Jones D
Thu Nov 19 00:00:00 EST 2009
Reciprocal role of GATA-1 and vitamin D receptor in human myeloid dendritic cell differentiation.
Blood
Göbel F,Taschner S,Jurkin J,Konradi S,Vaculik C,Richter S,Kneidinger D,Mühlbacher C,Bieglmayer C,Elbe-Bürger A,Strobl H
Thu Oct 29 00:00:00 EDT 2009
IFN-lambda1 (IL-29) inhibits GATA3 expression and suppresses Th2 responses in human naive and memory T cells.
Blood
Dai J,Megjugorac NJ,Gallagher GE,Yu RY,Gallagher G
Thu Jun 04 00:00:00 EDT 2009
Epstein-Barr virus (EBV)-encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3.
The Journal of experimental medicine
Iwakiri D,Zhou L,Samanta M,Matsumoto M,Ebihara T,Seya T,Imai S,Fujieda M,Kawa K,Takada K
Mon Sep 28 00:00:00 EDT 2009
Characterization and regulation of bv8 in human blood cells.
Clinical cancer research : an official journal of the American Association for Cancer Research
Zhong C,Qu X,Tan M,Meng YG,Ferrara N
Wed Apr 15 00:00:00 EDT 2009
Impaired STAT phosphorylation in T cells from melanoma patients in response to IL-2: association with clinical stage.
Clinical cancer research : an official journal of the American Association for Cancer Research
Mortarini R,Vegetti C,Molla A,Arienti F,Ravagnani F,Maurichi A,Patuzzo R,Santinami M,Anichini A
Mon Jun 15 00:00:00 EDT 2009
Heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin enhances EphA2+ tumor cell recognition by specific CD8+ T cells.
Cancer research
Kawabe M,Mandic M,Taylor JL,Vasquez CA,Wesa AK,Neckers LM,Storkus WJ
Tue Sep 01 00:00:00 EDT 2009
Different proliferative and survival capacity of CLL-cells in a newly established in vitro model for pseudofollicles.
Leukemia
Plander M,Seegers S,Ugocsai P,Diermeier-Daucher S,Iványi J,Schmitz G,Hofstädter F,Schwarz S,Orsó E,Knüchel R,Brockhoff G
Sun Nov 01 00:00:00 EDT 2009
Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition.
Proceedings of the National Academy of Sciences of the United States of America
Nicholls S,Piper KP,Mohammed F,Dafforn TR,Tenzer S,Salim M,Mahendra P,Craddock C,van Endert P,Schild H,Cobbold M,Engelhard VH,Moss PA,Willcox BE
Tue Mar 10 00:00:00 EDT 2009
Salmonella regulates polyubiquitination and surface expression of MHC class II antigens.
Proceedings of the National Academy of Sciences of the United States of America
Lapaque N,Hutchinson JL,Jones DC,Méresse S,Holden DW,Trowsdale J,Kelly AP
Tue Aug 18 00:00:00 EDT 2009
The role of transposable elements in the regulation of IFN-lambda1 gene expression.
Proceedings of the National Academy of Sciences of the United States of America
Thomson SJ,Goh FG,Banks H,Krausgruber T,Kotenko SV,Foxwell BM,Udalova IA
Tue Jul 14 00:00:00 EDT 2009
Cross-presenting human gammadelta T cells induce robust CD8+ alphabeta T cell responses.
Proceedings of the National Academy of Sciences of the United States of America
Brandes M,Willimann K,Bioley G,Lévy N,Eberl M,Luo M,Tampé R,Lévy F,Romero P,Moser B
Tue Feb 17 00:00:00 EST 2009
Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB.
Proceedings of the National Academy of Sciences of the United States of America
Porta C,Rimoldi M,Raes G,Brys L,Ghezzi P,Di Liberto D,Dieli F,Ghisletti S,Natoli G,De Baetselier P,Mantovani A,Sica A
Tue Sep 01 00:00:00 EDT 2009
Identification of tumor-associated, MHC class II-restricted phosphopeptides as targets for immunotherapy.
Proceedings of the National Academy of Sciences of the United States of America
Depontieu FR,Qian J,Zarling AL,McMiller TL,Salay TM,Norris A,English AM,Shabanowitz J,Engelhard VH,Hunt DF,Topalian SL
Tue Jul 21 00:00:00 EDT 2009
MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America
Ceppi M,Pereira PM,Dunand-Sauthier I,Barras E,Reith W,Santos MA,Pierre P
Tue Feb 24 00:00:00 EST 2009
A rapid crosstalk of human gammadelta T cells and monocytes drives the acute inflammation in bacterial infections.
PLoS pathogens
Eberl M,Roberts GW,Meuter S,Williams JD,Topley N,Moser B
Sun Feb 01 00:00:00 EST 2009
Human NKT cells promote monocyte differentiation into suppressive myeloid antigen-presenting cells.
Journal of leukocyte biology
Hegde S,Jankowska-Gan E,Roenneburg DA,Torrealba J,Burlingham WJ,Gumperz JE
Thu Oct 01 00:00:00 EDT 2009
Adenovirus-mediated gene transfer of pathogen-associated molecular patterns for cancer immunotherapy.
Cancer gene therapy
Tosch C,Geist M,Ledoux C,Ziller-Remi C,Paul S,Erbs P,Corvaia N,Von Hoegen P,Balloul JM,Haegel H
Wed Apr 01 00:00:00 EDT 2009
Reprogramming of a subpopulation of human blood neutrophils by prolonged exposure to cytokines.
Laboratory investigation; a journal of technical methods and pathology
Chakravarti A,Rusu D,Flamand N,Borgeat P,Poubelle PE
Thu Oct 01 00:00:00 EDT 2009
Aryl hydrocarbon receptor activation inhibits in vitro differentiation of human monocytes and Langerhans dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Platzer B,Richter S,Kneidinger D,Waltenberger D,Woisetschläger M,Strobl H
Wed Jul 01 00:00:00 EDT 2009
Increased intracellular, cell surface, and secreted inducible heat shock protein 70 responses are triggered during the monocyte to dendritic cell (DC) transition by cytokines independently of heat stress and infection and may positively regulate DC growth.
Journal of immunology (Baltimore, Md. : 1950)
Martin CA,Kurkowski DL,Valentino AM,Santiago-Schwarz F
Wed Jul 01 00:00:00 EDT 2009
MHC class I/peptide transfer between dendritic cells overcomes poor cross-presentation by monocyte-derived APCs that engulf dying cells.
Journal of immunology (Baltimore, Md. : 1950)
Qu C,Nguyen VA,Merad M,Randolph GJ
Sun Mar 15 00:00:00 EDT 2009
IL-12-dependent inducible expression of the CD94/NKG2A inhibitory receptor regulates CD94/NKG2C+ NK cell function.
Journal of immunology (Baltimore, Md. : 1950)
Sáez-Borderías A,Romo N,Magri G,Gumá M,Angulo A,López-Botet M
Thu Jan 15 00:00:00 EST 2009
HIV-1 Tat addresses dendritic cells to induce a predominant Th1-type adaptive immune response that appears prevalent in the asymptomatic stage of infection.
Journal of immunology (Baltimore, Md. : 1950)
Fanales-Belasio E,Moretti S,Fiorelli V,Tripiciano A,Pavone Cossut MR,Scoglio A,Collacchi B,Nappi F,Macchia I,Bellino S,Francavilla V,Caputo A,Barillari G,Magnani M,Laguardia ME,Cafaro A,Titti F,Monini P,Ensoli F,Ensoli B
Sun Mar 01 00:00:00 EST 2009
Identification of mycobacterial alpha-glucan as a novel ligand for DC-SIGN: involvement of mycobacterial capsular polysaccharides in host immune modulation.
Journal of immunology (Baltimore, Md. : 1950)
Geurtsen J,Chedammi S,Mesters J,Cot M,Driessen NN,Sambou T,Kakutani R,Ummels R,Maaskant J,Takata H,Baba O,Terashima T,Bovin N,Vandenbroucke-Grauls CM,Nigou J,Puzo G,Lemassu A,Daffé M,Appelmelk BJ
Thu Oct 15 00:00:00 EDT 2009
Enterobacter sakazakii targets DC-SIGN to induce immunosuppressive responses in dendritic cells by modulating MAPKs.
Journal of immunology (Baltimore, Md. : 1950)
Mittal R,Bulgheresi S,Emami C,Prasadarao NV
Sun Nov 15 00:00:00 EST 2009
Developmental switch of the expression of ion channels in human dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Zsiros E,Kis-Toth K,Hajdu P,Gaspar R,Bielanska J,Felipe A,Rajnavolgyi E,Panyi G
Thu Oct 01 00:00:00 EDT 2009
IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Kurowska-Stolarska M,Stolarski B,Kewin P,Murphy G,Corrigan CJ,Ying S,Pitman N,Mirchandani A,Rana B,van Rooijen N,Shepherd M,McSharry C,McInnes IB,Xu D,Liew FY
Sun Nov 15 00:00:00 EST 2009
C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Fraser DA,Laust AK,Nelson EL,Tenner AJ
Sun Nov 15 00:00:00 EST 2009
AS04, an aluminum salt- and TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunity.
Journal of immunology (Baltimore, Md. : 1950)
Didierlaurent AM,Morel S,Lockman L,Giannini SL,Bisteau M,Carlsen H,Kielland A,Vosters O,Vanderheyde N,Schiavetti F,Larocque D,Van Mechelen M,Garçon N
Sun Nov 15 00:00:00 EST 2009
Induction of cross-priming of naive CD8+ T lymphocytes by recombinant bacillus Calmette-Guerin that secretes heat shock protein 70-major membrane protein-II fusion protein.
Journal of immunology (Baltimore, Md. : 1950)
Mukai T,Maeda Y,Tamura T,Matsuoka M,Tsukamoto Y,Makino M
Sun Nov 15 00:00:00 EST 2009
1,25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype.
Journal of immunology (Baltimore, Md. : 1950)
Széles L,Keresztes G,Töröcsik D,Balajthy Z,Krenács L,Póliska S,Steinmeyer A,Zuegel U,Pruenster M,Rot A,Nagy L
Sun Feb 15 00:00:00 EST 2009
Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21.
Journal of immunology (Baltimore, Md. : 1950)
Hagn M,Schwesinger E,Ebel V,Sontheimer K,Maier J,Beyer T,Syrovets T,Laumonnier Y,Fabricius D,Simmet T,Jahrsdörfer B
Sat Aug 01 00:00:00 EDT 2009
Essential roles for Dok2 and RasGAP in CD200 receptor-mediated regulation of human myeloid cells.
Journal of immunology (Baltimore, Md. : 1950)
Mihrshahi R,Barclay AN,Brown MH
Thu Oct 15 00:00:00 EDT 2009
Dendritic cell anergy results from endotoxemia in severe malnutrition.
Journal of immunology (Baltimore, Md. : 1950)
Hughes SM,Amadi B,Mwiya M,Nkamba H,Tomkins A,Goldblatt D
Sat Aug 15 00:00:00 EDT 2009
Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950)
Podgrabinska S,Kamalu O,Mayer L,Shimaoka M,Snoeck H,Randolph GJ,Skobe M
Sat Aug 01 00:00:00 EDT 2009
Cysteinyl-leukotriene receptor type 1 expression and function is down-regulated during monocyte-derived dendritic cell maturation with zymosan: involvement of IL-10 and prostaglandins.
Journal of immunology (Baltimore, Md. : 1950)
Thivierge M,Stankova J,Rola-Pleszczynski M
Sun Nov 15 00:00:00 EST 2009
IL-4R(alpha), a new member that associates with Syk kinase: implication in IL-4-induced human neutrophil functions.
Journal of immunology (Baltimore, Md. : 1950)
Ennaciri J,Girard D
Thu Oct 15 00:00:00 EDT 2009
Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway.
Journal of immunology (Baltimore, Md. : 1950)
Scutera S,Fraone T,Musso T,Cappello P,Rossi S,Pierobon D,Orinska Z,Paus R,Bulfone-Paus S,Giovarelli M
Tue Sep 01 00:00:00 EDT 2009
IL-13R alpha 2 membrane and soluble isoforms differ in humans and mice.
Journal of immunology (Baltimore, Md. : 1950)
Chen W,Sivaprasad U,Tabata Y,Gibson AM,Stier MT,Finkelman FD,Hershey GK
Tue Dec 15 00:00:00 EST 2009
IL-13R alpha 2 membrane and soluble isoforms differ in humans and mice.
Journal of immunology (Baltimore, Md. : 1950)
Chen W,Sivaprasad U,Tabata Y,Gibson AM,Stier MT,Finkelman FD,Hershey GK
Tue Dec 15 00:00:00 EST 2009
Single nucleotide changes in the human Igamma1 and Igamma4 promoters underlie different transcriptional responses to CD40.
Journal of immunology (Baltimore, Md. : 1950)
Sinquett FL,Dryer RL,Marcelli V,Batheja A,Covey LR
Sun Feb 15 00:00:00 EST 2009
Microdialysis of cytokines: methodological considerations, scanning electron microscopy, and determination of relative recovery.
Journal of neurotrauma
Helmy A,Carpenter KL,Skepper JN,Kirkpatrick PJ,Pickard JD,Hutchinson PJ
Wed Apr 01 00:00:00 EDT 2009
Anthrax edema toxin induces maturation of dendritic cells and enhances chemotaxis towards macrophage inflammatory protein 3beta.
Infection and immunity
Maldonado-Arocho FJ,Bradley KA
Fri May 01 00:00:00 EDT 2009
The induction of APC with a distinct tolerogenic phenotype via contact-dependent STAT3 activation.
PloS one
Gur-Wahnon D,Borovsky Z,Liebergall M,Rachmilewitz J
Mon Aug 31 00:00:00 EDT 2009
Ribosomal protein mRNAs are translationally-regulated during human dendritic cells activation by LPS.
Immunome research
Ceppi M,Clavarino G,Gatti E,Schmidt EK,de Gassart A,Blankenship D,Ogola G,Banchereau J,Chaussabel D,Pierre P
Fri Nov 27 00:00:00 EST 2009
Distinct structural requirements for interleukin-4 (IL-4) and IL-13 binding to the shared IL-13 receptor facilitate cellular tuning of cytokine responsiveness.
The Journal of biological chemistry
Ito T,Suzuki S,Kanaji S,Shiraishi H,Ohta S,Arima K,Tanaka G,Tamada T,Honjo E,Garcia KC,Kuroki R,Izuhara K
Fri Sep 04 00:00:00 EDT 2009
Necator americanus infection: a possible cause of altered dendritic cell differentiation and eosinophil profile in chronically infected individuals.
PLoS neglected tropical diseases
Fujiwara RT,Cançado GG,Freitas PA,Santiago HC,Massara CL,Dos Santos Carvalho O,Corrêa-Oliveira R,Geiger SM,Bethony J
Mon Mar 08 00:00:00 EST 2010
Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts.
PloS one
Pilling D,Fan T,Huang D,Kaul B,Gomer RH
Fri Oct 16 00:00:00 EDT 2009
Comparison of the immunomodulatory properties of three probiotic strains of Lactobacilli using complex culture systems: prediction for in vivo efficacy.
PloS one
Mileti E,Matteoli G,Iliev ID,Rescigno M
Wed Sep 16 00:00:00 EDT 2009
The inhibitory receptor LILRB4 (ILT3) modulates antigen presenting cell phenotype and, along with LILRB2 (ILT4), is upregulated in response to Salmonella infection.
BMC immunology
Brown DP,Jones DC,Anderson KJ,Lapaque N,Buerki RA,Trowsdale J,Allen RL
Tue Oct 27 00:00:00 EDT 2009
Thrombospondin-1-N-terminal domain induces a phagocytic state and thrombospondin-1-C-terminal domain induces a tolerizing phenotype in dendritic cells.
PloS one
Tabib A,Krispin A,Trahtemberg U,Verbovetski I,Lebendiker M,Danieli T,Mevorach D
Mon Aug 31 00:00:00 EDT 2009
Human basophils activated by mast cell-derived IL-3 express retinaldehyde dehydrogenase-II and produce the immunoregulatory mediator retinoic acid.
Blood
Spiegl N,Didichenko S,McCaffery P,Langen H,Dahinden CA
Sat Nov 01 00:00:00 EDT 2008
Induction of CD4+ T-cell anergy and apoptosis by activated human B cells.
Blood
Tretter T,Venigalla RK,Eckstein V,Saffrich R,Sertel S,Ho AD,Lorenz HM
Mon Dec 01 00:00:00 EST 2008
Estrogen inhibits dendritic cell maturation to RNA viruses.
Blood
Escribese MM,Kraus T,Rhee E,Fernandez-Sesma A,López CB,Moran TM
Mon Dec 01 00:00:00 EST 2008
Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity.
The Journal of experimental medicine
Junttila IS,Mizukami K,Dickensheets H,Meier-Schellersheim M,Yamane H,Donnelly RP,Paul WE
Mon Oct 27 00:00:00 EDT 2008
Interferon-beta pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus.
PLoS pathogens
Phipps-Yonas H,Seto J,Sealfon SC,Moran TM,Fernandez-Sesma A
Wed Oct 01 00:00:00 EDT 2008
Myeloid dendritic cells display downregulation of C-type lectin receptors and aberrant lectin uptake in systemic lupus erythematosus.
Arthritis research & therapy
Monrad SU,Rea K,Thacker S,Kaplan MJ
Fri Feb 20 00:00:00 EST 2009
Human plasmacytoid dendritic cells interact with gp96 via CD91 and regulate inflammatory responses.
Journal of immunology (Baltimore, Md. : 1950)
De Filippo A,Binder RJ,Camisaschi C,Beretta V,Arienti F,Villa A,Della Mina P,Parmiani G,Rivoltini L,Castelli C
Sat Nov 01 00:00:00 EDT 2008
Antiviral-activated dendritic cells: a paracrine-induced response state.
Journal of immunology (Baltimore, Md. : 1950)
Bordería AV,Hartmann BM,Fernandez-Sesma A,Moran TM,Sealfon SC
Sat Nov 15 00:00:00 EST 2008
XCL1 enhances regulatory activities of CD4+ CD25(high) CD127(low/-) T cells in human allergic asthma.
Journal of immunology (Baltimore, Md. : 1950)
Nguyen KD,Fohner A,Booker JD,Dong C,Krensky AM,Nadeau KC
Wed Oct 15 00:00:00 EDT 2008
IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway.
Journal of immunology (Baltimore, Md. : 1950)
Krutzik SR,Hewison M,Liu PT,Robles JA,Stenger S,Adams JS,Modlin RL
Sat Nov 15 00:00:00 EST 2008
Histoplasma capsulatum cyclophilin A mediates attachment to dendritic cell VLA-5.
Journal of immunology (Baltimore, Md. : 1950)
Gomez FJ,Pilcher-Roberts R,Alborzi A,Newman SL
Sat Nov 15 00:00:00 EST 2008
The clathrin-mediated endocytic pathway participates in dsRNA-induced IFN-beta production.
Journal of immunology (Baltimore, Md. : 1950)
Itoh K,Watanabe A,Funami K,Seya T,Matsumoto M
Wed Oct 15 00:00:00 EDT 2008
Induction of TRAIL- and TNF-alpha-dependent apoptosis in human monocyte-derived dendritic cells by microfilariae of Brugia malayi.
Journal of immunology (Baltimore, Md. : 1950)
Semnani RT,Venugopal PG,Mahapatra L,Skinner JA,Meylan F,Chien D,Dorward DW,Chaussabel D,Siegel RM,Nutman TB
Sat Nov 15 00:00:00 EST 2008
Transduction with the antioxidant enzyme catalase protects human T cells against oxidative stress.
Journal of immunology (Baltimore, Md. : 1950)
Ando T,Mimura K,Johansson CC,Hanson MG,Mougiakakos D,Larsson C,Martins da Palma T,Sakurai D,Norell H,Li M,Nishimura MI,Kiessling R
Mon Dec 15 00:00:00 EST 2008
Regulation of alternative macrophage activation by galectin-3.
Journal of immunology (Baltimore, Md. : 1950)
MacKinnon AC,Farnworth SL,Hodkinson PS,Henderson NC,Atkinson KM,Leffler H,Nilsson UJ,Haslett C,Forbes SJ,Sethi T
Fri Feb 15 00:00:00 EST 2008
Dendritic cell differentiation signals induce anti-inflammatory properties in human adult microglia.
Journal of immunology (Baltimore, Md. : 1950)
Lambert C,Desbarats J,Arbour N,Hall JA,Olivier A,Bar-Or A,Antel JP
Mon Dec 15 00:00:00 EST 2008
Relationship of p53 overexpression on cancers and recognition by anti-p53 T cell receptor-transduced T cells.
Human gene therapy
Theoret MR,Cohen CJ,Nahvi AV,Ngo LT,Suri KB,Powell DJ,Dudley ME,Morgan RA,Rosenberg SA
Sat Nov 01 00:00:00 EDT 2008
Activin A induces Langerhans cell differentiation in vitro and in human skin explants.
PloS one
Musso T,Scutera S,Vermi W,Daniele R,Fornaro M,Castagnoli C,Alotto D,Ravanini M,Cambieri I,Salogni L,Elia AR,Giovarelli M,Facchetti F,Girolomoni G,Sozzani S
Wed Sep 24 00:00:00 EDT 2008
Genetically programmed differences in epidermal host defense between psoriasis and atopic dermatitis patients.
PloS one
Zeeuwen PL,de Jongh GJ,Rodijk-Olthuis D,Kamsteeg M,Verhoosel RM,van Rossum MM,Hiemstra PS,Schalkwijk J
Wed Jun 04 00:00:00 EDT 2008
HMGB1-dependent triggering of HIV-1 replication and persistence in dendritic cells as a consequence of NK-DC cross-talk.
PloS one
Saïdi H,Melki MT,Gougeon ML
Thu Feb 12 00:00:00 EST 2009
Direct contact of platelets and their released products exert different effects on human dendritic cell maturation.
BMC immunology
Hamzeh-Cognasse H,Cognasse F,Palle S,Chavarin P,Olivier T,Delézay O,Pozzetto B,Garraud O
Thu Sep 25 00:00:00 EDT 2008
A critical role for TNFalpha in the selective attachment of mononuclear leukocytes to angiotensin-II-stimulated arterioles.
Blood
Mateo T,Naim Abu Nabah Y,Losada M,Estellés R,Company C,Bedrina B,Cerdá-Nicolás JM,Poole S,Jose PJ,Cortijo J,Morcillo EJ,Sanz MJ
Sat Sep 15 00:00:00 EDT 2007
Natural killer cells trigger differentiation of monocytes into dendritic cells.
Blood
Zhang AL,Colmenero P,Purath U,Teixeira de Matos C,Hueber W,Klareskog L,Tarner IH,Engleman EG,Söderström K
Mon Oct 01 00:00:00 EDT 2007
Immune complexes inhibit differentiation, maturation, and function of human monocyte-derived dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Laborde EA,Vanzulli S,Beigier-Bompadre M,Isturiz MA,Ruggiero RA,Fourcade MG,Catalan Pellet AC,Sozzani S,Vulcano M
Sun Jul 01 00:00:00 EDT 2007
Invariant NKT cells biased for IL-5 production act as crucial regulators of inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Sakuishi K,Oki S,Araki M,Porcelli SA,Miyake S,Yamamura T
Sat Sep 15 00:00:00 EDT 2007
Soluble TNF-like cytokine (TL1A) production by immune complexes stimulated monocytes in rheumatoid arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Cassatella MA,Pereira-da-Silva G,Tinazzi I,Facchetti F,Scapini P,Calzetti F,Tamassia N,Wei P,Nardelli B,Roschke V,Vecchi A,Mantovani A,Bambara LM,Edwards SW,Carletto A
Fri Jun 01 00:00:00 EDT 2007
Interferon-lambda-treated dendritic cells specifically induce proliferation of FOXP3-expressing suppressor T cells.
Blood
Mennechet FJ,Uzé G
Thu Jun 01 00:00:00 EDT 2006
Interferon-lambda-treated dendritic cells specifically induce proliferation of FOXP3-expressing suppressor T cells.
Blood
Mennechet FJ,Uzé G
Thu Jun 01 00:00:00 EDT 2006
Multidirectional interactions are bridging human NK cells with plasmacytoid and monocyte-derived dendritic cells during innate immune responses.
Blood
Della Chiesa M,Romagnani C,Thiel A,Moretta L,Moretta A
Fri Dec 01 00:00:00 EST 2006
The inhibitory receptor IRp60 (CD300a) suppresses the effects of IL-5, GM-CSF, and eotaxin on human peripheral blood eosinophils.
Blood
Munitz A,Bachelet I,Eliashar R,Moretta A,Moretta L,Levi-Schaffer F
Wed Mar 01 00:00:00 EST 2006
CC-chemokine ligand 16 induces a novel maturation program in human immature monocyte-derived dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Cappello P,Fraone T,Barberis L,Costa C,Hirsch E,Elia AR,Caorsi C,Musso T,Novelli F,Giovarelli M
Wed Nov 01 00:00:00 EST 2006
NK-dependent DC maturation is mediated by TNFalpha and IFNgamma released upon engagement of the NKp30 triggering receptor.
Blood
Vitale M,Della Chiesa M,Carlomagno S,Pende D,Aricò M,Moretta L,Moretta A
Fri Jul 15 00:00:00 EDT 2005
Human airway epithelial cell determinants of survival and functional phenotype for primary human mast cells.
Proceedings of the National Academy of Sciences of the United States of America
Hsieh FH,Sharma P,Gibbons A,Goggans T,Erzurum SC,Haque SJ
Tue Oct 04 00:00:00 EDT 2005
Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation.
Journal of immunology (Baltimore, Md. : 1950)
van Beek J,van Meurs M,'t Hart BA,Brok HP,Neal JW,Chatagner A,Harris CL,Omidvar N,Morgan BP,Laman JD,Gasque P
Tue Feb 15 00:00:00 EST 2005
Cellular basis of the role of diesel exhaust particles in inducing Th2-dominant response.
Journal of immunology (Baltimore, Md. : 1950)
Ohtani T,Nakagawa S,Kurosawa M,Mizuashi M,Ozawa M,Aiba S
Tue Feb 15 00:00:00 EST 2005
CCR4 ligands are up-regulated in the airways of atopic asthmatics after segmental allergen challenge.
The European respiratory journal
Pilette C,Francis JN,Till SJ,Durham SR
Tue Jun 01 00:00:00 EDT 2004
CCR4 ligands are up-regulated in the airways of atopic asthmatics after segmental allergen challenge.
The European respiratory journal
Pilette C,Francis JN,Till SJ,Durham SR
Tue Jun 01 00:00:00 EDT 2004
Are interleukin-16 and thrombopoietin new tools for the in vitro generation of dendritic cells?
Blood
Della Bella S,Nicola S,Timofeeva I,Villa ML,Santoro A,Berardi AC
Wed Dec 15 00:00:00 EST 2004
Chemokine receptor-mediated delivery directs self-tumor antigen efficiently into the class II processing pathway in vitro and induces protective immunity in vivo.
Blood
Biragyn A,Ruffini PA,Coscia M,Harvey LK,Neelapu SS,Baskar S,Wang JM,Kwak LW
Fri Oct 01 00:00:00 EDT 2004
Selective recognition of fibroblast growth factor-2 by the long pentraxin PTX3 inhibits angiogenesis.
Blood
Rusnati M,Camozzi M,Moroni E,Bottazzi B,Peri G,Indraccolo S,Amadori A,Mantovani A,Presta M
Thu Jul 01 00:00:00 EDT 2004
Selective recognition of fibroblast growth factor-2 by the long pentraxin PTX3 inhibits angiogenesis.
Blood
Rusnati M,Camozzi M,Moroni E,Bottazzi B,Peri G,Indraccolo S,Amadori A,Mantovani A,Presta M
Thu Jul 01 00:00:00 EDT 2004
Monocyte derived dendritic cell responses in common variable immunodeficiency.
Clinical and experimental immunology
Scott-Taylor TH,Green MR,Eren E,Webster AD
200-04 was used in Cell Culture to study the function of monocyte derived dendritic cells (MdDC) in 25 patients with common variable immunodeficiency (CVID) to discern the failure of antibody production. DCs from the majority of CVID patients were normal, while 5 patients susceptible and with affected family members expressed abnormally low levels of DR. DCs from many CVID patients had high spontaneous production of IL-8 and lipopolysaccharide stimulation often caused by a reduction in DR expres
Wed Dec 01 00:00:00 EST 2004
Monocyte derived dendritic cell responses in common variable immunodeficiency.
Clinical and experimental immunology
Scott-Taylor TH,Green MR,Eren E,Webster AD
200-04 was used in Cell Culture to study the function of monocyte derived dendritic cells (MdDC) in 25 patients with common variable immunodeficiency (CVID) to discern the failure of antibody production. DCs from the majority of CVID patients were normal, while 5 patients susceptible and with affected family members expressed abnormally low levels of DR. DCs from many CVID patients had high spontaneous production of IL-8 and lipopolysaccharide stimulation often caused by a reduction in DR expres
Wed Dec 01 00:00:00 EST 2004
Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression.
Cancer research
Hemminki A,Kanerva A,Liu B,Wang M,Alvarez RD,Siegal GP,Curiel DT
Sat Feb 15 00:00:00 EST 2003
CD1-dependent dendritic cell instruction.
Nature immunology
Vincent MS,Leslie DS,Gumperz JE,Xiong X,Grant EP,Brenner MB
Sun Dec 01 00:00:00 EST 2002
CD1-mediated gamma/delta T cell maturation of dendritic cells.
The Journal of experimental medicine
Leslie DS,Vincent MS,Spada FM,Das H,Sugita M,Morita CT,Brenner MB
Mon Dec 16 00:00:00 EST 2002
Role of tyrosine phosphorylation in ligand-independent sequestration of CXCR4 in human primary monocytes-macrophages.
The Journal of biological chemistry
Wang J,Guan E,Roderiquez G,Calvert V,Alvarez R,Norcross MA
Fri Dec 28 00:00:00 EST 2001
Immune responses to Plasmodium falciparum-merozoite surface protein 1 (MSP1) antigen, II. Induction of parasite-specific immunoglobulin G in unsensitized human B cells after in vitro T-cell priming with MSP119.
Immunology
Garraud O,Diouf A,Holm I,Perraut R,Longacre S
Thu Jul 01 00:00:00 EDT 1999
CD40-Mediated induction of CD4 and CXCR4 on B lymphocytes correlates with restricted susceptibility to human immunodeficiency virus type 1 infection: potential role of B lymphocytes as a viral reservoir.
Journal of virology
Moir S,Lapointe R,Malaspina A,Ostrowski M,Cole CE,Chun TW,Adelsberger J,Baseler M,Hwu P,Fauci AS
Fri Oct 01 00:00:00 EDT 1999
A 135,000 molecular weight plasma membrane glycoprotein involved in fibronectin-mediated cell adhesion. Immunofluorescence localization in normal and RSV-transformed fibroblasts.
Experimental cell research
Giancotti FG,Comoglio PM,Tarone G
Sat Mar 01 00:00:00 EST 1986
Studies of thiamine metabolism in man; thiamine and pyrimidine excretion with special reference to the relationship between injected and excreted thiamine in normal and abnormal subjects.
The Journal of clinical investigation
ALEXANDER B,LANDWEHR G,MITCHELL F
Wed May 01 00:00:00 EDT 1946