Product References
Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells.
Nature communications
Igarashi N,Miyata K,Loo TM,Chiba M,Hanyu A,Nishio M,Kawasaki H,Zheng H,Toyokuni S,Kon S,Moriyama K,Fujita Y,Takahashi A
200-08M was used in Competition Assay to provide evidence that cellular senescence inhibits cell competition-mediated elimination of oncogenic cells through HGF signaling, suggesting that it may lead to cancer incidence during aging.
Mon Jul 18 00:00:00 EDT 2022
PECAM-1 supports leukocyte diapedesis by tension-dependent dephosphorylation of VE-cadherin.
The EMBO journal
Arif N,Zinnhardt M,Nyamay'Antu A,Teber D,Brückner R,Schaefer K,Li YT,Trappmann B,Grashoff C,Vestweber D
Mon May 03 00:00:00 EDT 2021
FABP4 deactivates NF-κB-IL1α pathway by ubiquitinating ATPB in tumor-associated macrophages and promotes neuroblastoma progression.
Clinical and translational medicine
Miao L,Zhuo Z,Tang J,Huang X,Liu J,Wang HY,Xia H,He J
Thu Apr 01 00:00:00 EDT 2021
Inflammatory Cell Death, PANoptosis, Mediated by Cytokines in Diverse Cancer Lineages Inhibits Tumor Growth.
ImmunoHorizons
Malireddi RKS,Karki R,Sundaram B,Kancharana B,Lee S,Samir P,Kanneganti TD
200-08M was used in Cell Culture to investigate correlations between cytokine expression and mortality.
Wed Jul 21 00:00:00 EDT 2021
CXCL8 Associated Dendritic Cell Activation Marker Expression and Recruitment as Indicators of Favorable Outcomes in Colorectal Cancer.
Frontiers in immunology
Li E,Yang X,Du Y,Wang G,Chan DW,Wu D,Xu P,Ni P,Xu D,Hu Y
200-08M was used in In vitro experiments to identify the tumor microenvironment (TME)-related gene CXCL8 in a high-ImmuneScore population that contributed to better survival in colorectal cancer (CRC) patients from The Cancer Genome Atlas (TCGA) database.
Mon Oct 25 00:00:00 EDT 2021
CXCL8 Associated Dendritic Cell Activation Marker Expression and Recruitment as Indicators of Favorable Outcomes in Colorectal Cancer.
Frontiers in immunology
Li E,Yang X,Du Y,Wang G,Chan DW,Wu D,Xu P,Ni P,Xu D,Hu Y
200-08M was used in In vitro experiments to identify the tumor microenvironment (TME)-related gene CXCL8 in a high-ImmuneScore population that contributed to better survival in colorectal cancer (CRC) patients from The Cancer Genome Atlas (TCGA) database.
Mon Oct 25 00:00:00 EDT 2021
Kinetics of peripheral blood neutrophils in severe coronavirus disease 2019.
Clinical & translational immunology
Metzemaekers M,Cambier S,Blanter M,Vandooren J,de Carvalho AC,Malengier-Devlies B,Vanderbeke L,Jacobs C,Coenen S,Martens E,Pörtner N,Vanbrabant L,Van Mol P,Van Herck Y,Van Aerde N,Hermans G,Gunst J,Borin A,Toledo N Pereira B,Dos Sp Gomes AB,Primon Muraro S,Fabiano de Souza G,S Farias A,Proenca-Modena JL,R Vinolo MA,Marques PE,Wouters C,Wauters E,Struyf S,Matthys P,Opdenakker G,Marques RE,Wauters J,Gouwy M,Proost P
Fri Apr 22 00:00:00 EDT 2022
N2-Polarized Neutrophils Guide Bone Mesenchymal Stem Cell Recruitment and Initiate Bone Regeneration: A Missing Piece of the Bone Regeneration Puzzle.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cai B,Lin D,Li Y,Wang L,Xie J,Dai T,Liu F,Tang M,Tian L,Yuan Y,Kong L,Shen SGF
Fri Oct 01 00:00:00 EDT 2021
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.
Cell
Blanco-Melo D,Nilsson-Payant BE,Liu WC,Uhl S,Hoagland D,Møller R,Jordan TX,Oishi K,Panis M,Sachs D,Wang TT,Schwartz RE,Lim JK,Albrecht RA,tenOever BR
Thu May 28 00:00:00 EDT 2020
Local microvascular leakage promotes trafficking of activated neutrophils to remote organs.
The Journal of clinical investigation
Owen-Woods C,Joulia R,Barkaway A,Rolas L,Ma B,Nottebaum AF,Arkill KP,Stein M,Girbl T,Golding M,Bates DO,Vestweber D,Voisin MB,Nourshargh S
Fri May 01 00:00:00 EDT 2020
The interaction of interleukin-8 and PTEN inactivation promotes the malignant progression of head and neck squamous cell carcinoma via the STAT3 pathway.
Cell death & disease
Xu Q,Ma H,Chang H,Feng Z,Zhang C,Yang X
Fri May 29 00:00:00 EDT 2020
Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival.
Nature communications
Dietachmayr M,Rathakrishnan A,Karpiuk O,von Zweydorf F,Engleitner T,Fernández-Sáiz V,Schenk P,Ueffing M,Rad R,Eilers M,Gloeckner CJ,Clemm von Hohenberg K,Bassermann F
Mon Mar 09 00:00:00 EDT 2020
Oxidative stress enhanced the transforming growth factor-β2-induced epithelial-mesenchymal transition through chemokine ligand 1 on ARPE-19 cell.
Scientific reports
Yang IH,Lee JJ,Wu PC,Kuo HK,Kuo YH,Huang HM
Wed Mar 04 00:00:00 EST 2020
PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease.
The Journal of clinical investigation
Li Y,Hu Q,Li C,Liang K,Xiang Y,Hsiao H,Nguyen TK,Park PK,Egranov SD,Ambati CR,Putluri N,Hawke DH,Han L,Hung MC,Danesh FR,Yang L,Lin C
Fri Mar 01 00:00:00 EST 2019
Mammalian diaphanous-related formin 1 (mDia1) coordinates mast cell migration and secretion through its actin-nucleating activity.
The Journal of allergy and clinical immunology
Klein O,Krier-Burris RA,Lazki-Hagenbach P,Gorzalczany Y,Mei Y,Ji P,Bochner BS,Sagi-Eisenberg R
200-08M was used in Cell Culture to identify mDia1 as a novel regulator of MC response that coordinates MC chemotaxis and secretion through its actin-nucleating activity.
Tue Oct 01 00:00:00 EDT 2019
TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling.
Cell reports
Kasitinon SY,Eskiocak U,Martin M,Bezwada D,Khivansara V,Tasdogan A,Zhao Z,Mathews T,Aurora AB,Morrison SJ
200-08M was used in Cell Culture to determine that Mucolipin-1 is preferentially required for the survival and proliferation of melanoma cells.
Tue Aug 27 00:00:00 EDT 2019
Serum FHR1 binding to necrotic-type cells activates monocytic inflammasome and marks necrotic sites in vasculopathies.
Nature communications
Irmscher S,Brix SR,Zipfel SLH,Halder LD,Mutlutürk S,Wulf S,Girdauskas E,Reichenspurner H,Stahl RAK,Jungnickel B,Wiech T,Zipfel PF,Skerka C
Thu Jul 04 00:00:00 EDT 2019
COOH-terminal SAA1 peptides fail to induce chemokines but synergize with CXCL8 and CCL3 to recruit leukocytes via FPR2.
Blood
De Buck M,Gouwy M,Berghmans N,Opdenakker G,Proost P,Struyf S,Van Damme J
Thu Jan 25 00:00:00 EST 2018
IL-8 mediates idiopathic pulmonary fibrosis mesenchymal progenitor cell fibrogenicity.
American journal of physiology. Lung cellular and molecular physiology
Yang L,Herrera J,Gilbertsen A,Xia H,Smith K,Benyumov A,Bitterman PB,Henke CA
Mon Jan 01 00:00:00 EST 2018
Surveillance of Myelodysplastic Syndrome via Migration Analyses of Blood Neutrophils: A Potential Prognostic Tool.
Journal of immunology (Baltimore, Md. : 1950)
Schuster M,Moeller M,Bornemann L,Bessen C,Sobczak C,Schmitz S,Witjes L,Kruithoff K,Kohn C,Just O,Kündgen A,Pundt N,Pelzer B,Ampe C,Van Troys M,Nusch A,Haas R,Germing U,Martens L,Jöckel KH,Gunzer M
Sat Dec 15 00:00:00 EST 2018
JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell-induced protection of AML.
Blood
Karjalainen R,Pemovska T,Popa M,Liu M,Javarappa KK,Majumder MM,Yadav B,Tamborero D,Tang J,Bychkov D,Kontro M,Parsons A,Suvela M,Mayoral Safont M,Porkka K,Aittokallio T,Kallioniemi O,McCormack E,Gjertsen BT,Wennerberg K,Knowles J,Heckman CA
Thu Aug 10 00:00:00 EDT 2017
Strict tropism for CD71+/CD234+ human reticulocytes limits the zoonotic potential of Plasmodium cynomolgi.
Blood
Kosaisavee V,Suwanarusk R,Chua ACY,Kyle DE,Malleret B,Zhang R,Imwong M,Imerbsin R,Ubalee R,Sámano-Sánchez H,Yeung BKS,Ong JJY,Lombardini E,Nosten F,Tan KSW,Bifani P,Snounou G,Rénia L,Russell B
Thu Sep 14 00:00:00 EDT 2017
Co-Inflammatory Roles of TGFβ1 in the Presence of TNFα Drive a Pro-inflammatory Fate in Mesenchymal Stem Cells.
Frontiers in immunology
Lerrer S,Liubomirski Y,Bott A,Abnaof K,Oren N,Yousaf A,Körner C,Meshel T,Wiemann S,Ben-Baruch A
200-08M was used in Enzyme-linked immunosorbent assay to demonstrate a TNFα + TGFβ1-driven pro-inflammatory fate in MSCs, identify specific molecular mechanisms involved, and propose that TNFα + TGFβ1-stimulated MSCs influence the tumor niche.
Wed Nov 20 00:00:00 EST 2019
Stimulation of oral fibroblast chemokine receptors identifies CCR3 and CCR4 as potential wound healing targets.
Journal of cellular physiology
Buskermolen JK,Roffel S,Gibbs S
Wed Nov 01 00:00:00 EDT 2017
Extracellular matrix protein laminin enhances mesenchymal stem cell (MSC) paracrine function through αvβ3/CD61 integrin to reduce cardiomyocyte apoptosis.
Journal of cellular and molecular medicine
Peng KY,Liu YH,Li YW,Yen BL,Yen ML
Tue Aug 01 00:00:00 EDT 2017
Blastomyces dermatitidis serine protease dipeptidyl peptidase IVA (DppIVA) cleaves ELR+ CXC chemokines altering their effects on neutrophils.
Cellular microbiology
Lorenzini J,Scott Fites J,Nett J,Klein BS
200-08M was used in Sample Preparation to investigate the effects of DppIVA on neutrophils recruitment.
Fri Sep 01 00:00:00 EDT 2017
Blastomyces dermatitidis serine protease dipeptidyl peptidase IVA (DppIVA) cleaves ELR+ CXC chemokines altering their effects on neutrophils.
Cellular microbiology
Lorenzini J,Scott Fites J,Nett J,Klein BS
200-08M was used in Sample Preparation to investigate the effects of DppIVA on neutrophils recruitment.
Fri Sep 01 00:00:00 EDT 2017
FGF23 signaling impairs neutrophil recruitment and host defense during CKD.
The Journal of clinical investigation
Rossaint J,Oehmichen J,Van Aken H,Reuter S,Pavenstädt HJ,Meersch M,Unruh M,Zarbock A
Tue Mar 01 00:00:00 EST 2016
FGF23 signaling impairs neutrophil recruitment and host defense during CKD.
The Journal of clinical investigation
Rossaint J,Oehmichen J,Van Aken H,Reuter S,Pavenstädt HJ,Meersch M,Unruh M,Zarbock A
Tue Mar 01 00:00:00 EST 2016
NAP-2 Secreted by Human NK Cells Can Stimulate Mesenchymal Stem/Stromal Cell Recruitment.
Stem cell reports
Almeida CR,Caires HR,Vasconcelos DP,Barbosa MA
Tue Apr 12 00:00:00 EDT 2016
Serum amyloid A1α induces paracrine IL-8/CXCL8 via TLR2 and directly synergizes with this chemokine via CXCR2 and formyl peptide receptor 2 to recruit neutrophils.
Journal of leukocyte biology
De Buck M,Berghmans N,Pörtner N,Vanbrabant L,Cockx M,Struyf S,Opdenakker G,Proost P,Van Damme J,Gouwy M
Tue Dec 01 00:00:00 EST 2015
Macrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors.
Journal of immunology (Baltimore, Md. : 1950)
Lourenco S,Teixeira VH,Kalber T,Jose RJ,Floto RA,Janes SM
Wed Apr 01 00:00:00 EDT 2015
Cross-Talk between Shp1 and PIPKIγ Controls Leukocyte Recruitment.
Journal of immunology (Baltimore, Md. : 1950)
Stadtmann A,Block H,Volmering S,Abram C,Sohlbach C,Boras M,Lowell CA,Zarbock A
Sat Aug 01 00:00:00 EDT 2015
Sensitizing protective tumor microenvironments to antibody-mediated therapy.
Cell
Pallasch CP,Leskov I,Braun CJ,Vorholt D,Drake A,Soto-Feliciano YM,Bent EH,Schwamb J,Iliopoulou B,Kutsch N,van Rooijen N,Frenzel LP,Wendtner CM,Heukamp L,Kreuzer KA,Hallek M,Chen J,Hemann MT
Thu Jan 30 00:00:00 EST 2014
A positive feedback loop between mesenchymal-like cancer cells and macrophages is essential to breast cancer metastasis.
Cancer cell
Su S,Liu Q,Chen J,Chen J,Chen F,He C,Huang D,Wu W,Lin L,Huang W,Zhang J,Cui X,Zheng F,Li H,Yao H,Su F,Song E
Mon May 12 00:00:00 EDT 2014
CD24-triggered caspase-dependent apoptosis via mitochondrial membrane depolarization and reactive oxygen species production of human neutrophils is impaired in sepsis.
Journal of immunology (Baltimore, Md. : 1950)
Parlato M,Souza-Fonseca-Guimaraes F,Philippart F,Misset B,Adib-Conquy M,Cavaillon JM
Sat Mar 01 00:00:00 EST 2014
Lidocaine reduces neutrophil recruitment by abolishing chemokine-induced arrest and transendothelial migration in septic patients.
Journal of immunology (Baltimore, Md. : 1950)
Berger C,Rossaint J,Van Aken H,Westphal M,Hahnenkamp K,Zarbock A
Wed Jan 01 00:00:00 EST 2014
G Protein-coupled receptor kinase-6 interacts with activator of G protein signaling-3 to regulate CXCR2-mediated cellular functions.
Journal of immunology (Baltimore, Md. : 1950)
Singh V,Raghuwanshi SK,Smith N,Rivers EJ,Richardson RM
Sat Mar 01 00:00:00 EST 2014
G Protein-coupled receptor kinase-6 interacts with activator of G protein signaling-3 to regulate CXCR2-mediated cellular functions.
Journal of immunology (Baltimore, Md. : 1950)
Singh V,Raghuwanshi SK,Smith N,Rivers EJ,Richardson RM
Sat Mar 01 00:00:00 EST 2014
G Protein-coupled receptor kinase-6 interacts with activator of G protein signaling-3 to regulate CXCR2-mediated cellular functions.
Journal of immunology (Baltimore, Md. : 1950)
Singh V,Raghuwanshi SK,Smith N,Rivers EJ,Richardson RM
Sat Mar 01 00:00:00 EST 2014
PC3-secreted microprotein is a novel chemoattractant protein and functions as a high-affinity ligand for CC chemokine receptor 2.
Journal of immunology (Baltimore, Md. : 1950)
Pei X,Sun Q,Zhang Y,Wang P,Peng X,Guo C,Xu E,Zheng Y,Mo X,Ma J,Chen D,Zhang Y,Zhang Y,Song Q,Guo S,Shi T,Zhang Z,Ma D,Wang Y
Sat Feb 15 00:00:00 EST 2014
A biased non-Gαi OXE-R antagonist demonstrates that Gαi protein subunit is not directly involved in neutrophil, eosinophil, and monocyte activation by 5-oxo-ETE.
Journal of immunology (Baltimore, Md. : 1950)
Konya V,Blättermann S,Jandl K,Platzer W,Ottersbach PA,Marsche G,Gütschow M,Kostenis E,Heinemann A
Thu May 15 00:00:00 EDT 2014
Regulation of T cell proliferation by JMJD6 and PDGF-BB during chronic hepatitis B infection.
Scientific reports
Chen CF,Feng X,Liao HY,Jin WJ,Zhang J,Wang Y,Gong LL,Liu JJ,Yuan XH,Zhao BB,Zhang D,Chen GF,Wan Y,Guo J,Yan HP,He YW
Mon Sep 15 00:00:00 EDT 2014
Integrin activation by P-Rex1 is required for selectin-mediated slow leukocyte rolling and intravascular crawling.
Blood
Herter JM,Rossaint J,Block H,Welch H,Zarbock A
Thu Mar 21 00:00:00 EDT 2013
Dipeptidyl peptidase IV is a human and murine neutrophil chemorepellent.
Journal of immunology (Baltimore, Md. : 1950)
Herlihy SE,Pilling D,Maharjan AS,Gomer RH
Sat Jun 15 00:00:00 EDT 2013
A chemokine self-presentation mechanism involving formation of endothelial surface microstructures.
Journal of immunology (Baltimore, Md. : 1950)
Whittall C,Kehoe O,King S,Rot A,Patterson A,Middleton J
Fri Feb 15 00:00:00 EST 2013
Dasatinib inhibits proinflammatory functions of mature human neutrophils.
Blood
Futosi K,Németh T,Pick R,Vántus T,Walzog B,Mócsai A
Thu May 24 00:00:00 EDT 2012
ALK+ALCLs induce cutaneous, HMGB-1-dependent IL-8/CXCL8 production by keratinocytes through NF-κB activation.
Blood
Dejean E,Foisseau M,Lagarrigue F,Lamant L,Prade N,Marfak A,Delsol G,Giuriato S,Gaits-Iacovoni F,Meggetto F
Thu May 17 00:00:00 EDT 2012
L-selectin and SDF-1 enhance the migration of mouse and human cardiac mesoangioblasts.
Cell death and differentiation
Bernal A,San Martín N,Fernández M,Covarello D,Molla F,Soldo A,Latini R,Cossu G,Gálvez BG
Wed Feb 01 00:00:00 EST 2012
Inactivation of staphylococcal phenol soluble modulins by serum lipoprotein particles.
PLoS pathogens
Surewaard BG,Nijland R,Spaan AN,Kruijtzer JA,de Haas CJ,van Strijp JA
Mon Jul 09 00:00:00 EDT 2012
Inhibition of epidermal growth factor receptor tyrosine kinase ameliorates collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Swanson CD,Akama-Garren EH,Stein EA,Petralia JD,Ruiz PJ,Edalati A,Lindstrom TM,Robinson WH
Sun Apr 01 00:00:00 EDT 2012
Proteinase 3 contributes to transendothelial migration of NB1-positive neutrophils.
Journal of immunology (Baltimore, Md. : 1950)
Kuckleburg CJ,Tilkens SB,Santoso S,Newman PJ
Thu Mar 01 00:00:00 EST 2012
The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions.
Journal of immunology (Baltimore, Md. : 1950)
Raghuwanshi SK,Su Y,Singh V,Haynes K,Richmond A,Richardson RM
Sat Sep 15 00:00:00 EDT 2012
Transgenesis-mediated reproductive dysfunction and tumorigenesis: effects of immunological neutralization.
PloS one
Sachdeva R,Bhardwaj N,Huhtaniemi I,Aggrawal U,Jain SK,Zaidi R,Singh O,Pal R
Tue May 28 00:00:00 EDT 2013
Apolipoproteins and apolipoprotein mimetic peptides modulate phagocyte trafficking through chemotactic activity.
The Journal of biological chemistry
Madenspacher JH,Azzam KM,Gong W,Gowdy KM,Vitek MP,Laskowitz DT,Remaley AT,Wang JM,Fessler MB
Fri Dec 21 00:00:00 EST 2012
Streptococcus pyogenes SpyCEP influences host-pathogen interactions during infection in a murine air pouch model.
PloS one
Chiappini N,Seubert A,Telford JL,Grandi G,Serruto D,Margarit I,Janulczyk R
Tue Apr 02 00:00:00 EDT 2013
Streptococcus pyogenes SpyCEP influences host-pathogen interactions during infection in a murine air pouch model.
PloS one
Chiappini N,Seubert A,Telford JL,Grandi G,Serruto D,Margarit I,Janulczyk R
Tue Apr 02 00:00:00 EDT 2013
Cardiopulmonary bypass during cardiac surgery modulates systemic inflammation by affecting different steps of the leukocyte recruitment cascade.
PloS one
Rossaint J,Berger C,Van Aken H,Scheld HH,Zahn PK,Rukosujew A,Zarbock A
Thu Mar 28 00:00:00 EDT 2013
Constitutive and treatment-induced CXCL8-signalling selectively modulates the efficacy of anti-metabolite therapeutics in metastatic prostate cancer.
PloS one
Wilson C,Maxwell PJ,Longley DB,Wilson RH,Johnston PG,Waugh DJ
Wed Sep 19 00:00:00 EDT 2012
Glioblastoma cell-secreted interleukin-8 induces brain endothelial cell permeability via CXCR2.
PloS one
Dwyer J,Hebda JK,Le Guelte A,Galan-Moya EM,Smith SS,Azzi S,Bidere N,Gavard J
Wed Mar 06 00:00:00 EST 2013
Angiostatic and chemotactic activities of the CXC chemokine CXCL4L1 (platelet factor-4 variant) are mediated by CXCR3.
Blood
Struyf S,Salogni L,Burdick MD,Vandercappellen J,Gouwy M,Noppen S,Proost P,Opdenakker G,Parmentier M,Gerard C,Sozzani S,Strieter RM,Van Damme J
Thu Jan 13 00:00:00 EST 2011
Myeloperoxidase attracts neutrophils by physical forces.
Blood
Klinke A,Nussbaum C,Kubala L,Friedrichs K,Rudolph TK,Rudolph V,Paust HJ,Schröder C,Benten D,Lau D,Szocs K,Furtmüller PG,Heeringa P,Sydow K,Duchstein HJ,Ehmke H,Schumacher U,Meinertz T,Sperandio M,Baldus S
Thu Jan 27 00:00:00 EST 2011
MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases.
Breast cancer research : BCR
Pivetta E,Scapolan M,Pecolo M,Wassermann B,Abu-Rumeileh I,Balestreri L,Borsatti E,Tripodo C,Colombatti A,Spessotto P
Thu Oct 27 00:00:00 EDT 2011
TLT2 potentiates neutrophil antibacterial activity and chemotaxis in response to G protein-coupled receptor-mediated signaling.
Journal of immunology (Baltimore, Md. : 1950)
Halpert MM,Thomas KA,King RG,Justement LB
Thu Sep 01 00:00:00 EDT 2011
EBF and dried blood spots: from recommendations to potential resolution.
Bioanalysis
Timmerman P,White S,Globig S,Lüdtke S,Brunet L,Smith C,Smeraglia J
Mon Aug 01 00:00:00 EDT 2011
Chemokines and inflammatory mediators interact to regulate adult murine neural precursor cell proliferation, survival and differentiation.
PloS one
Turbic A,Leong SY,Turnley AM
Fri Feb 10 00:00:00 EST 2012
Host chemokines bind to Staphylococcus aureus and stimulate protein A release.
The Journal of biological chemistry
Yung SC,Parenti D,Murphy PM
Fri Feb 18 00:00:00 EST 2011
Disease-associated GPR56 mutations cause bilateral frontoparietal polymicrogyria via multiple mechanisms.
The Journal of biological chemistry
Chiang NY,Hsiao CC,Huang YS,Chen HY,Hsieh IJ,Chang GW,Lin HH
Fri Apr 22 00:00:00 EDT 2011
Amplification of the angiogenic signal through the activation of the TSC/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma.
PloS one
Jham BC,Ma T,Hu J,Chaisuparat R,Friedman ER,Pandolfi PP,Schneider A,Sodhi A,Montaner S
Fri Apr 29 00:00:00 EDT 2011
Interleukin-8 induces the endothelial cell migration through the activation of phosphoinositide 3-kinase-Rac1/RhoA pathway.
International journal of biological sciences
Lai Y,Shen Y,Liu XH,Zhang Y,Zeng Y,Liu YF
Mon Nov 07 00:00:00 EST 2011
A revised model for the secretion of tPA and cytokines from cultured endothelial cells.
Blood
Knipe L,Meli A,Hewlett L,Bierings R,Dempster J,Skehel P,Hannah MJ,Carter T
Thu Sep 23 00:00:00 EDT 2010
RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo.
Blood
Frommhold D,Kamphues A,Hepper I,Pruenster M,Lukic IK,Socher I,Zablotskaya V,Buschmann K,Lange-Sperandio B,Schymeinsky J,Ryschich E,Poeschl J,Kupatt C,Nawroth PP,Moser M,Walzog B,Bierhaus A,Sperandio M
Thu Aug 05 00:00:00 EDT 2010
The IgG-specific endoglycosidase EndoS inhibits both cellular and complement-mediated autoimmune hemolysis.
Blood
Allhorn M,Briceño JG,Baudino L,Lood C,Olsson ML,Izui S,Collin M
Thu Jun 17 00:00:00 EDT 2010
The IgG-specific endoglycosidase EndoS inhibits both cellular and complement-mediated autoimmune hemolysis.
Blood
Allhorn M,Briceño JG,Baudino L,Lood C,Olsson ML,Izui S,Collin M
Thu Jun 17 00:00:00 EDT 2010
Rolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA-1 in neutrophils.
Blood
Kuwano Y,Spelten O,Zhang H,Ley K,Zarbock A
Thu Jul 29 00:00:00 EDT 2010
Evidence for a cross-talk between human neutrophils and Th17 cells.
Blood
Pelletier M,Maggi L,Micheletti A,Lazzeri E,Tamassia N,Costantini C,Cosmi L,Lunardi C,Annunziato F,Romagnani S,Cassatella MA
Thu Jan 14 00:00:00 EST 2010
Injury is a major inducer of epidermal innate immune responses during wound healing.
The Journal of investigative dermatology
Roupé KM,Nybo M,Sjöbring U,Alberius P,Schmidtchen A,Sørensen OE
Thu Apr 01 00:00:00 EDT 2010
Internalization and coreceptor expression are critical for TLR2-mediated recognition of lipoteichoic acid in human peripheral blood.
Journal of immunology (Baltimore, Md. : 1950)
Bunk S,Sigel S,Metzdorf D,Sharif O,Triantafilou K,Triantafilou M,Hartung T,Knapp S,von Aulock S
Wed Sep 15 00:00:00 EDT 2010
sRAGE induces human monocyte survival and differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Wang Y,Wang H,Piper MG,McMaken S,Mo X,Opalek J,Schmidt AM,Marsh CB
Sun Aug 01 00:00:00 EDT 2010
Trans- but not cis-resveratrol impairs angiotensin-II-mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated receptor-gamma upregulation.
Journal of immunology (Baltimore, Md. : 1950)
Rius C,Abu-Taha M,Hermenegildo C,Piqueras L,Cerda-Nicolas JM,Issekutz AC,Estañ L,Cortijo J,Morcillo EJ,Orallo F,Sanz MJ
Wed Sep 15 00:00:00 EDT 2010
Trans- but not cis-resveratrol impairs angiotensin-II-mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated receptor-gamma upregulation.
Journal of immunology (Baltimore, Md. : 1950)
Rius C,Abu-Taha M,Hermenegildo C,Piqueras L,Cerda-Nicolas JM,Issekutz AC,Estañ L,Cortijo J,Morcillo EJ,Orallo F,Sanz MJ
Wed Sep 15 00:00:00 EDT 2010
CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses.
Journal of immunology (Baltimore, Md. : 1950)
Carbone T,Nasorri F,Pennino D,Eyerich K,Foerster S,Cifaldi L,Traidl-Hoffman C,Behrendt H,Cavani A
Fri Jan 15 00:00:00 EST 2010
Chemokine scavenger D6 is expressed by trophoblasts and aids the survival of mouse embryos transferred into allogeneic recipients.
Journal of immunology (Baltimore, Md. : 1950)
Madigan J,Freeman DJ,Menzies F,Forrow S,Nelson SM,Young A,Sharkey A,Moffett A,Graham GJ,Greer IA,Rot A,Nibbs RJ
Mon Mar 15 00:00:00 EDT 2010
Inhibiting TRAF2-mediated activation of NF-kappaB facilitates induction of AP-1.
The Journal of biological chemistry
Manna SK,Babajan B,Raghavendra PB,Raviprakash N,Sureshkumar C
Fri Apr 09 00:00:00 EDT 2010
Cytosolic group IVa phospholipase A2 mediates IL-8/CXCL8-induced transmigration of human polymorphonuclear leukocytes in vitro.
Journal of inflammation (London, England)
Meliton AY,Muñoz NM,Meliton LN,Binder DC,Osan CM,Zhu X,Dudek SM,Leff AR
Thu Mar 18 00:00:00 EDT 2010
Azadirachtin interacts with the tumor necrosis factor (TNF) binding domain of its receptors and inhibits TNF-induced biological responses.
The Journal of biological chemistry
Thoh M,Kumar P,Nagarajaram HA,Manna SK
Fri Feb 19 00:00:00 EST 2010
Dynamic interaction networks in a hierarchically organized tissue.
Molecular systems biology
Kirouac DC,Ito C,Csaszar E,Roch A,Yu M,Sykes EA,Bader GD,Zandstra PW
Tue Oct 05 00:00:00 EDT 2010
Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice.
Nature medicine
Koenen RR,von Hundelshausen P,Nesmelova IV,Zernecke A,Liehn EA,Sarabi A,Kramp BK,Piccinini AM,Paludan SR,Kowalska MA,Kungl AJ,Hackeng TM,Mayo KH,Weber C
Thu Jan 01 00:00:00 EST 2009
Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses.
Nature immunology
Nakano H,Lin KL,Yanagita M,Charbonneau C,Cook DN,Kakiuchi T,Gunn MD
Wed Apr 01 00:00:00 EDT 2009
Loss of red cell chemokine scavenging promotes transfusion-related lung inflammation.
Blood
Mangalmurti NS,Xiong Z,Hulver M,Ranganathan M,Liu XH,Oriss T,Fitzpatrick M,Rubin M,Triulzi D,Choi A,Lee JS
Thu Jan 29 00:00:00 EST 2009
Characterization and regulation of bv8 in human blood cells.
Clinical cancer research : an official journal of the American Association for Cancer Research
Zhong C,Qu X,Tan M,Meng YG,Ferrara N
Wed Apr 15 00:00:00 EDT 2009
A feeder-free and efficient production of functional neutrophils from human embryonic stem cells.
Stem cells (Dayton, Ohio)
Saeki K,Saeki K,Nakahara M,Matsuyama S,Nakamura N,Yogiashi Y,Yoneda A,Koyanagi M,Kondo Y,Yuo A
Thu Jan 01 00:00:00 EST 2009
Immunomodulatory activity of oenothein B isolated from Epilobium angustifolium.
Journal of immunology (Baltimore, Md. : 1950)
Schepetkin IA,Kirpotina LN,Jakiw L,Khlebnikov AI,Blaskovich CL,Jutila MA,Quinn MT
Sun Nov 15 00:00:00 EST 2009
Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan.
Journal of immunology (Baltimore, Md. : 1950)
Abu-Taha M,Rius C,Hermenegildo C,Noguera I,Cerda-Nicolas JM,Issekutz AC,Jose PJ,Cortijo J,Morcillo EJ,Sanz MJ
Wed Jul 15 00:00:00 EDT 2009
Coronin-1 is associated with neutrophil survival and is cleaved during apoptosis: potential implication in neutrophils from cystic fibrosis patients.
Journal of immunology (Baltimore, Md. : 1950)
Moriceau S,Kantari C,Mocek J,Davezac N,Gabillet J,Guerrera IC,Brouillard F,Tondelier D,Sermet-Gaudelus I,Danel C,Lenoir G,Daniel S,Edelman A,Witko-Sarsat V
Mon Jun 01 00:00:00 EDT 2009
A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2.
Journal of immunology (Baltimore, Md. : 1950)
Izhak L,Wildbaum G,Zohar Y,Anunu R,Klapper L,Elkeles A,Seagal J,Yefenof E,Ayalon-Soffer M,Karin N
Wed Jul 01 00:00:00 EDT 2009
A homolog of formyl peptide receptor-like 1 (FPRL1) inhibitor from Staphylococcus aureus (FPRL1 inhibitory protein) that inhibits FPRL1 and FPR.
Journal of immunology (Baltimore, Md. : 1950)
Prat C,Haas PJ,Bestebroer J,de Haas CJ,van Strijp JA,van Kessel KP
Sun Nov 15 00:00:00 EST 2009
Dynamic regulation of CXCR1 and CXCR2 homo- and heterodimers.
Journal of immunology (Baltimore, Md. : 1950)
Martínez Muñoz L,Lucas P,Navarro G,Checa AI,Franco R,Martínez-A C,Rodríguez-Frade JM,Mellado M
Tue Dec 01 00:00:00 EST 2009
Microdialysis of cytokines: methodological considerations, scanning electron microscopy, and determination of relative recovery.
Journal of neurotrauma
Helmy A,Carpenter KL,Skepper JN,Kirkpatrick PJ,Pickard JD,Hutchinson PJ
Wed Apr 01 00:00:00 EDT 2009
Streptococcus agalactiae CspA is a serine protease that inactivates chemokines.
Journal of bacteriology
Bryan JD,Shelver DW
Sun Mar 01 00:00:00 EST 2009
The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation.
The Journal of biological chemistry
Schröder R,Merten N,Mathiesen JM,Martini L,Kruljac-Letunic A,Krop F,Blaukat A,Fang Y,Tran E,Ulven T,Drewke C,Whistler J,Pardo L,Gomeza J,Kostenis E
Fri Jan 09 00:00:00 EST 2009
SpeB of Streptococcus pyogenes differentially modulates antibacterial and receptor activating properties of human chemokines.
PloS one
Egesten A,Olin AI,Linge HM,Yadav M,Mörgelin M,Karlsson A,Collin M
Mon Jun 15 00:00:00 EDT 2009
Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases.
Journal of immunology (Baltimore, Md. : 1950)
Hartl D,Krauss-Etschmann S,Koller B,Hordijk PL,Kuijpers TW,Hoffmann F,Hector A,Eber E,Marcos V,Bittmann I,Eickelberg O,Griese M,Roos D
Mon Dec 01 00:00:00 EST 2008
Prostaglandin E2 inhibits eosinophil trafficking through E-prostanoid 2 receptors.
Journal of immunology (Baltimore, Md. : 1950)
Sturm EM,Schratl P,Schuligoi R,Konya V,Sturm GJ,Lippe IT,Peskar BA,Heinemann A
Sat Nov 15 00:00:00 EST 2008
Chemokine and cytokine mediated loss of regulatory T cells in lymph nodes during pathogenic simian immunodeficiency virus infection.
Journal of immunology (Baltimore, Md. : 1950)
Qin S,Sui Y,Soloff AC,Junecko BA,Kirschner DE,Murphey-Corb MA,Watkins SC,Tarwater PM,Pease JE,Barratt-Boyes SM,Reinhart TA
Tue Apr 15 00:00:00 EDT 2008
Effect of lipopolysaccharide (LPS) and peptidoglycan (PGN) on human mast cell numbers, cytokine production, and protease composition.
BMC immunology
Kirshenbaum AS,Swindle E,Kulka M,Wu Y,Metcalfe DD
Thu Aug 07 00:00:00 EDT 2008
CXCL10 blockade protects mice from cyclophosphamide-induced cystitis.
Journal of immune based therapies and vaccines
Sakthivel SK,Singh UP,Singh S,Taub DD,Novakovic KR,Lillard JW
Tue Oct 28 00:00:00 EDT 2008
CXCR2 blockade impairs angiotensin II-induced CC chemokine synthesis and mononuclear leukocyte infiltration.
Arteriosclerosis, thrombosis, and vascular biology
Abu Nabah YN,Losada M,Estellés R,Mateo T,Company C,Piqueras L,Lopez-Gines C,Sarau H,Cortijo J,Morcillo EJ,Jose PJ,Sanz MJ
Thu Nov 01 00:00:00 EDT 2007
CXCR2 blockade impairs angiotensin II-induced CC chemokine synthesis and mononuclear leukocyte infiltration.
Arteriosclerosis, thrombosis, and vascular biology
Abu Nabah YN,Losada M,Estellés R,Mateo T,Company C,Piqueras L,Lopez-Gines C,Sarau H,Cortijo J,Morcillo EJ,Jose PJ,Sanz MJ
Thu Nov 01 00:00:00 EDT 2007
The inhibitory receptor IRp60 (CD300a) suppresses the effects of IL-5, GM-CSF, and eotaxin on human peripheral blood eosinophils.
Blood
Munitz A,Bachelet I,Eliashar R,Moretta A,Moretta L,Levi-Schaffer F
Wed Mar 01 00:00:00 EST 2006
Circulating IL-8 and anti-IL-8 autoantibody in patients with ovarian cancer.
Gynecologic oncology
Lokshin AE,Winans M,Landsittel D,Marrangoni AM,Velikokhatnaya L,Modugno F,Nolen BM,Gorelik E
Tue Aug 01 00:00:00 EDT 2006
The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bioavailability via inhibition and binding to cargo receptors.
The Journal of biological chemistry
Van den Steen PE,Van Aelst I,Hvidberg V,Piccard H,Fiten P,Jacobsen C,Moestrup SK,Fry S,Royle L,Wormald MR,Wallis R,Rudd PM,Dwek RA,Opdenakker G
Fri Jul 07 00:00:00 EDT 2006
Agonists of toll-like receptors 2 and 4 activate airway smooth muscle via mononuclear leukocytes.
American journal of respiratory and critical care medicine
Morris GE,Whyte MK,Martin GF,Jose PJ,Dower SK,Sabroe I
Fri Apr 15 00:00:00 EDT 2005
Human herpesvirus 7 open reading frames U12 and U51 encode functional beta-chemokine receptors.
Journal of virology
Tadagaki K,Nakano K,Yamanishi K
Wed Jun 01 00:00:00 EDT 2005
Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation.
Journal of immunology (Baltimore, Md. : 1950)
van Beek J,van Meurs M,'t Hart BA,Brok HP,Neal JW,Chatagner A,Harris CL,Omidvar N,Morgan BP,Laman JD,Gasque P
Tue Feb 15 00:00:00 EST 2005
Human tumor antigen MUC1 is chemotactic for immature dendritic cells and elicits maturation but does not promote Th1 type immunity.
Journal of immunology (Baltimore, Md. : 1950)
Carlos CA,Dong HF,Howard OM,Oppenheim JJ,Hanisch FG,Finn OJ
Mon Aug 01 00:00:00 EDT 2005
Angiotensin II induces neutrophil accumulation in vivo through generation and release of CXC chemokines.
Circulation
Nabah YN,Mateo T,Estellés R,Mata M,Zagorski J,Sarau H,Cortijo J,Morcillo EJ,Jose PJ,Sanz MJ
Tue Dec 07 00:00:00 EST 2004
Selective recognition of fibroblast growth factor-2 by the long pentraxin PTX3 inhibits angiogenesis.
Blood
Rusnati M,Camozzi M,Moroni E,Bottazzi B,Peri G,Indraccolo S,Amadori A,Mantovani A,Presta M
Thu Jul 01 00:00:00 EDT 2004
Selective recognition of fibroblast growth factor-2 by the long pentraxin PTX3 inhibits angiogenesis.
Blood
Rusnati M,Camozzi M,Moroni E,Bottazzi B,Peri G,Indraccolo S,Amadori A,Mantovani A,Presta M
Thu Jul 01 00:00:00 EDT 2004
Enhanced protein profiling arrays with ELISA-based amplification for high-throughput molecular changes of tumor patients' plasma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Huang R,Lin Y,Shi Q,Flowers L,Ramachandran S,Horowitz IR,Parthasarathy S,Huang RP
Thu Jan 15 00:00:00 EST 2004
Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.
Proceedings of the National Academy of Sciences of the United States of America
Bertini R,Allegretti M,Bizzarri C,Moriconi A,Locati M,Zampella G,Cervellera MN,Di Cioccio V,Cesta MC,Galliera E,Martinez FO,Di Bitondo R,Troiani G,Sabbatini V,D'Anniballe G,Anacardio R,Cutrin JC,Cavalieri B,Mainiero F,Strippoli R,Villa P,Di Girolamo M,Martin F,Gentile M,Santoni A,Corda D,Poli G,Mantovani A,Ghezzi P,Colotta F
Tue Aug 10 00:00:00 EDT 2004
Identification of selective basophil chemoattractants in human nasal polyps as insulin-like growth factor-1 and insulin-like growth factor-2.
Journal of immunology (Baltimore, Md. : 1950)
Hartnell A,Heinemann A,Conroy DM,Wait R,Sturm GJ,Caversaccio M,Jose PJ,Williams TJ
Mon Nov 15 00:00:00 EST 2004
Human P-selectin glycoprotein ligand-1 (PSGL-1) interacts with the skin-associated chemokine CCL27 via sulfated tyrosines at the PSGL-1 amino terminus.
The Journal of biological chemistry
Hirata T,Furukawa Y,Yang BG,Hieshima K,Fukuda M,Kannagi R,Yoshie O,Miyasaka M
Fri Dec 10 00:00:00 EST 2004
The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis.
The Journal of biological chemistry
Waldhoer M,Casarosa P,Rosenkilde MM,Smit MJ,Leurs R,Whistler JL,Schwartz TW
Fri May 23 00:00:00 EDT 2003
Ligand-independent CXCR2 dimerization.
The Journal of biological chemistry
Trettel F,Di Bartolomeo S,Lauro C,Catalano M,Ciotti MT,Limatola C
Fri Oct 17 00:00:00 EDT 2003
Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists.
American journal of respiratory and critical care medicine
Bryan SA,Jose PJ,Topping JR,Wilhelm R,Soderberg C,Kertesz D,Barnes PJ,Williams TJ,Hansel TT,Sabroe I
Sat Jun 15 00:00:00 EDT 2002
The role of HIV-related chemokine receptors and chemokines in human erythropoiesis in vitro.
Stem cells (Dayton, Ohio)
Majka M,Ratajczak J,Lee B,Honczarenko M,Douglas R,Kowalska MA,Silberstein L,Gewirtz AM,Ratajczak MZ
Mon Jun 26 00:00:00 EDT 2000
MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions.
Nature
Gerszten RE,Garcia-Zepeda EA,Lim YC,Yoshida M,Ding HA,Gimbrone MA,Luster AD,Luscinskas FW,Rosenzweig A
Thu Apr 22 00:00:00 EDT 1999
Mast cell migratory response to interleukin-8 is mediated through interaction with chemokine receptor CXCR2/Interleukin-8RB.
Blood
Nilsson G,Mikovits JA,Metcalfe DD,Taub DD
Sat May 01 00:00:00 EDT 1999
The first subcomponent of complement, C1q, triggers the production of IL-8, IL-6, and monocyte chemoattractant peptide-1 by human umbilical vein endothelial cells.
Journal of immunology (Baltimore, Md. : 1950)
van den Berg RH,Faber-Krol MC,Sim RB,Daha MR
Tue Dec 15 00:00:00 EST 1998
The first subcomponent of complement, C1q, triggers the production of IL-8, IL-6, and monocyte chemoattractant peptide-1 by human umbilical vein endothelial cells.
Journal of immunology (Baltimore, Md. : 1950)
van den Berg RH,Faber-Krol MC,Sim RB,Daha MR
Tue Dec 15 00:00:00 EST 1998
The first subcomponent of complement, C1q, triggers the production of IL-8, IL-6, and monocyte chemoattractant peptide-1 by human umbilical vein endothelial cells.
Journal of immunology (Baltimore, Md. : 1950)
van den Berg RH,Faber-Krol MC,Sim RB,Daha MR
Tue Dec 15 00:00:00 EST 1998
Identification of single C motif-1/lymphotactin receptor XCR1.
The Journal of biological chemistry
Yoshida T,Imai T,Kakizaki M,Nishimura M,Takagi S,Yoshie O
Fri Jun 26 00:00:00 EDT 1998
Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1.
The Journal of experimental medicine
Sarafi MN,Garcia-Zepeda EA,MacLean JA,Charo IF,Luster AD
Mon Jan 06 00:00:00 EST 1997
Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309.
The Journal of experimental medicine
Tiffany HL,Lautens LL,Gao JL,Pease J,Locati M,Combadiere C,Modi W,Bonner TI,Murphy PM
Mon Jul 07 00:00:00 EDT 1997
Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309.
The Journal of experimental medicine
Tiffany HL,Lautens LL,Gao JL,Pease J,Locati M,Combadiere C,Modi W,Bonner TI,Murphy PM
Mon Jul 07 00:00:00 EDT 1997