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This peptide corresponds to 16 amino acids near the carboxy terminus of human KANK2.
PEP-1582 can be used as a blocking peptide with polyclonal antibody PA5-34539. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37ºC.
This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair.
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Protein Aliases: Ankyrin repeat domain-containing protein 25; kidney ankyrin repeat-containing protein 2; KN motif and ankyrin repeat domain-containing protein 2; Matrix-remodeling-associated protein 3; SIP; SRC-1-interacting protein; SRC-interacting protein; SRC1-interacting protein
Gene Aliases: ANKRD25; KANK2; KIAA1518; MXRA3; PPKWH; SIP
UniProt ID: (Human) Q63ZY3
Entrez Gene ID: (Human) 25959
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