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Invitrogen
Human LRRC26 (aa 44-85) Control Fragment Recombinant Protein
Product Details
RP-100074
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
PEVCTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRA
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (67%), Rat (67%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63285. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The LRRC26 protein was initially identified as a cytokeratin-associated protein whose expression was elevated in multiple cancer cell lines and cancer specimens as well in normal prostate and salivary gland tissues. LRRC26 was later found to negatively regulate the NF-kappaB activation and suppresses tumor growth and metastasis. LRRC26 can also act to selectively alter the efficacy of large conductance calcium-activated K (BK) channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BK channel auxiliary gamma subunit LRRC26; BK channel auxilliary gamma subunit LRRC26; cytokeratin associated protein; Cytokeratin-associated protein in cancer; Leucine-rich repeat-containing protein 26
Gene Aliases: bA350O14.10; CAPC; LRRC26
UniProt ID: (Human) Q2I0M4
Entrez Gene ID: (Human) 389816
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