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          • Proteins & Peptides ›
          • SAPK4 Proteins

          Invitrogen

          Human MAPK13 (p38 delta), His Tag Recombinant Protein

          View all (3) SAPK4 proteins

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          Cite Human MAPK13 (p38 delta), His Tag Recombinant Protein

          Product Details

          PV4017

          Applications
          Tested Dilution
          Publications

          Kinase Assay (KA)

          Assay-dependent
          -
          Product Specifications

          Species

          Human

          Expression System

          Baculovirus

          Amino acid sequence

          Full length

          Tag

          His-tag

          Molecular weight

          46.2 kDa

          Class

          Recombinant

          Type

          Protein

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          See Label

          Purification

          purified

          Storage buffer

          50mM tris, pH 7.5, with 0.02% Triton X-100, 50% glycerol, 0.5mM EDTA, 150mM NaCl, 2mM DTT

          Contains

          no preservative

          Storage conditions

          -80°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Dry ice

          Product Specific Information

          For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.

          Protein Form: Full Length

          Target Information

          MAPK13 (p38 delta) is a serine/threonine kinase that transduces a variety of extracellular signals, including cytokine and environmental stress responses. MAPK13 also regulates the differentiation of keratinocytes. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases, or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of SAPK4 encoding distinct isoforms have been reported.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: MAP kinase 13; MAP kinase p38 delta; Mitogen-activated protein kinase 13; Mitogen-activated protein kinase p38 delta; Stress-activated protein kinase 4

          View more View less

          Gene Aliases: MAPK 13; MAPK-13; MAPK13; p38delta; PRKM13; SAPK4

          View more View less

          UniProt ID: (Human) O15264

          View more View less

          Entrez Gene ID: (Human) 5603

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          It has to be done as per old AB suggested Products section.
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