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Invitrogen
Human MARK3 (aa 399-548) Control Fragment Recombinant Protein
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Product Details
RP-89020
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
QSPHHKVQRSVSSSQKQRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKEDGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSSTVPSSNTASGGMTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAA
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82890. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
MARK3 is a member of a group of kinases known to regulate cell polarity via phosphorylation of microtubule-associated proteins (MAPs). The protein encoded by MARK3 is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for MARK3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-TAK1; Cdc25C-associated protein kinase 1; cTAK1; ELKL motif kinase 2; EMK-2; MAP/microtubule affinity-regulating kinase 3; Par-1a; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Serine/threonine-protein kinase p78
Gene Aliases: CTAK1; EMK2; KP78; MARK3; Par-1a; PAR1A
UniProt ID: (Human) P27448
Entrez Gene ID: (Human) 4140
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