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Invitrogen
Human MARVELD1 Synthetic Peptide
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Product Details
PEP-0967
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
This peptide corresponds to 16 amino acids near the amino terminus of human MARVELD1.
PEP-0967 can be used as a blocking peptide with polyclonal antibody PA5-20853.
Target Information
MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MARVEL (membrane-associating) domain containing 1; MARVEL domain-containing protein 1; occludin; putative MARVEL domain-containing protein 1; RP11-548K23.8
Gene Aliases: bA548K23.8; GB14; MARVD1; MARVELD1; MRVLDC1
UniProt ID: (Human) Q9BSK0
Entrez Gene ID: (Human) 83742
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