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PeproTech's HEK293 cell-derived Recombinant Human MD-2/LY96 is a disulfide-linked homodimer whose monomer contains 148 amino acid residues, including a C-terminal His tag, and has a calculated molecular weight of 17.2 kDa.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
MD-2 is a gene that encodes a protein involved in the recognition of bacterial lipopolysaccharides (LPS) by the immune system. It is located on chromosome 8 and is part of a larger family of genes that encode for similar proteins. The MD-2 protein forms a complex with Toll-like receptor 4 (TLR4) to recognize and respond to LPS, triggering an immune response. Mutations or variations in the MD-2 gene have been associated with various diseases and conditions, including sepsis and inflammatory disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ESOP-1; Ly-96; Lymphocyte antigen 96; myeloid differentiation protein-2; Protein MD-2
Gene Aliases: ESOP-1; ESOP1; ly-96; LY96; MD-2; MD2
UniProt ID: (Human) Q9Y6Y9
Entrez Gene ID: (Human) 23643
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