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Invitrogen
Human MSH2 (aa 37-120) Control Fragment Recombinant Protein
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Product Details
RP-108519
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
FDRGDFYTAHGEDALLAAREVFKTQGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLA
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Plays a role in neurogenesis and neuronal migration. Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA mismatch repair protein Msh2; DNA mismatch repair protein Msh2 transcript; Frameshift mutation results in premature stop; hMSH2; homolog of S. cerevisiae Msh2p [Swiss-Prot accession number P25847] and bacterial MutS proteins [Swiss-Prot accession numbers P23909, P10339, and P27345]; Insertion mutation results in premature stop; Msh2p; mutation causes premature stop; mutS homolog 2, colon cancer, nonpolyposis type 1; MutS protein homolog 2; MutS-like 2; premature stop codon due to mutation; The base insertion results in premature stop; The deletion results in premature stop.; unnamed protein product
Gene Aliases: COCA1; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2; LYNCH1; MMRCS2; MSH-2; MSH2
UniProt ID: (Human) P43246
Entrez Gene ID: (Human) 4436
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