Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (28%), Rat (28%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-139943. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Matrix-remodeling-associated protein 5 (MXRA5), also known as adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan (Adlican), is a 2,828 amino acid secretory protein. Containing 12 Ig-like C2-type domains and 7 LRR repeats, MXRA5 is a member of the leucine-rich repeat and Ig domain-containing (LRRIG) family of proteins. MXRA5 expression, while decreasing with age from youth until late adulthood, increases from late adulthood through late elderhood. Most notably, NXRA5 has been shown to be overexpressed in centenarians. This expression pattern suggests a role of MXRA5 in the biology of aging and longevity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan; Adlican; Matrix-remodeling-associated protein 5; matrix-remodelling associated 5
Gene Aliases: MXRA5
UniProt ID: (Human) Q9NR99
Entrez Gene ID: (Human) 25878
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