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Highest antigen sequence indentity to the following orthologs: Mouse (87%), Rat (87%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53393. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
MYLK4 serine/threonine kinase or myosin light chain kinase family member 4 is a member of the CAMK kinase family. It is one of four myosin light chain kinases noted in a comprehensive analysis of protein kinases encoded by the human genome. MLCKs are activated by Ca2+-calmodulin complexes and require Mg2+ or Ca2+ as a co-factor. It has 2 isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: caMLCK like; Myosin light chain kinase family member 4; myosin light chain kinase family, member 4; SgK085; Sugen kinase 85
Gene Aliases: MYLK4; SGK085
UniProt ID: (Human) Q86YV6
Entrez Gene ID: (Human) 340156
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