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Invitrogen
Human Meteorin (aa 197-260) Control Fragment Recombinant Protein
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Product Details
RP-101168
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
VTHDVELQESVITVVAARVLRQTPPLFQAGRSGDQGLTSIRTPLRCGVHPGPGTFLFMGWSRFG
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (77%), Rat (77%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62335. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Meteorin is a gene encoding a protein that is part of the cytokine and growth factor family, primarily involved in neurogenesis and gliogenesis. It is located on chromosome 17p13.1 and is highly expressed in the nervous system, where it plays a role in promoting the differentiation and maturation of astrocytes and neural precursor cells. Meteorin functions by enhancing neurite outgrowth and synaptic development, crucial for proper neural network formation. Additionally, it has been implicated in angiogenesis, contributing to the development and maintenance of blood vessels in neural tissue. Research suggests that Meteorin has neuroprotective properties and may help in recovery from neural injury, making it a molecule of interest for therapeutic strategies in neurodegenerative diseases and brain injuries. Its expression and activity are also being studied in relation to inflammatory responses and potential roles in other tissues, offering insights into its diverse biological functions beyond the central nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Meteorin
Gene Aliases: C16orf23; c380A1.2; METRN; RJD6
UniProt ID: (Human) Q9UJH8
Entrez Gene ID: (Human) 79006
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