Product References
Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state.
Nature medicine
Cerezo-Wallis D,Contreras-Alcalde M,Troulé K,Catena X,Mucientes C,Calvo TG,Cañón E,Tejedo C,Pennacchi PC,Hogan S,Kölblinger P,Tejero H,Chen AX,Ibarz N,Graña-Castro O,Martinez L,Muñoz J,Ortiz-Romero P,Rodriguez-Peralto JL,Gómez-López G,Al-Shahrour F,Rabadán R,Levesque MP,Olmeda D,Soengas MS
Tue Dec 01 00:00:00 EST 2020
Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis.
The Journal of experimental medicine
Weckbach LT,Grabmaier U,Uhl A,Gess S,Boehm F,Zehrer A,Pick R,Salvermoser M,Czermak T,Pircher J,Sorrelle N,Migliorini M,Strickland DK,Klingel K,Brinkmann V,Abu Abed U,Eriksson U,Massberg S,Brunner S,Walzog B
Mon Feb 04 00:00:00 EST 2019
Novel Biological Substrates of Human Kallikrein 7 Identified through Degradomics.
The Journal of biological chemistry
Yu Y,Prassas I,Dimitromanolakis A,Diamandis EP
Fri Jul 17 00:00:00 EDT 2015
The cytokine midkine supports neutrophil trafficking during acute inflammation by promoting adhesion via β2 integrins (CD11/CD18).
Blood
Weckbach LT,Gola A,Winkelmann M,Jakob SM,Groesser L,Borgolte J,Pogoda F,Pick R,Pruenster M,Müller-Höcker J,Deindl E,Sperandio M,Walzog B
Thu Mar 20 00:00:00 EDT 2014
The cytokine midkine supports neutrophil trafficking during acute inflammation by promoting adhesion via β2 integrins (CD11/CD18).
Blood
Weckbach LT,Gola A,Winkelmann M,Jakob SM,Groesser L,Borgolte J,Pogoda F,Pick R,Pruenster M,Müller-Höcker J,Deindl E,Sperandio M,Walzog B
Thu Mar 20 00:00:00 EDT 2014
The cytokine midkine and its receptor RPTPζ regulate B cell survival in a pathway induced by CD74.
Journal of immunology (Baltimore, Md. : 1950)
Cohen S,Shoshana OY,Zelman-Toister E,Maharshak N,Binsky-Ehrenreich I,Gordin M,Hazan-Halevy I,Herishanu Y,Shvidel L,Haran M,Leng L,Bucala R,Harroch S,Shachar I
Sun Jan 01 00:00:00 EST 2012
Constitutive and inflammation-dependent antimicrobial peptides produced by epithelium are differentially processed and inactivated by the commensal Finegoldia magna and the pathogen Streptococcus pyogenes.
Journal of immunology (Baltimore, Md. : 1950)
Frick IM,Nordin SL,Baumgarten M,Mörgelin M,Sørensen OE,Olin AI,Egesten A
Sat Oct 15 00:00:00 EDT 2011
Midkine and pleiotrophin have bactericidal properties: preserved antibacterial activity in a family of heparin-binding growth factors during evolution.
The Journal of biological chemistry
Svensson SL,Pasupuleti M,Walse B,Malmsten M,Mörgelin M,Sjögren C,Olin AI,Collin M,Schmidtchen A,Palmer R,Egesten A
Fri May 21 00:00:00 EDT 2010
Fibroblast growth factor 4 and its novel splice isoform have opposing effects on the maintenance of human embryonic stem cell self-renewal.
Stem cells (Dayton, Ohio)
Mayshar Y,Rom E,Chumakov I,Kronman A,Yayon A,Benvenisty N
Sat Mar 01 00:00:00 EST 2008
Midkine is a NF-kappaB-inducible gene that supports prostate cancer cell survival.
BMC medical genomics
You Z,Dong Y,Kong X,Beckett LA,Gandour-Edwards R,Melamed J
Thu Feb 14 00:00:00 EST 2008
Chondroitinase-mediated degradation of rare 3-O-sulfated glucuronic acid in functional oversulfated chondroitin sulfate K and E.
The Journal of biological chemistry
Fongmoon D,Shetty AK,Yamada S,Sugiura M,Kongtawelert P,Sugahara K
Fri Dec 21 00:00:00 EST 2007
Neuritogenic activity of chondroitin/dermatan sulfate hybrid chains of embryonic pig brain and their mimicry from shark liver. Involvement of the pleiotrophin and hepatocyte growth factor signaling pathways.
The Journal of biological chemistry
Li F,Shetty AK,Sugahara K
Fri Feb 02 00:00:00 EST 2007
Sulfation patterns of glycosaminoglycans encode molecular recognition and activity.
Nature chemical biology
Gama CI,Tully SE,Sotogaku N,Clark PM,Rawat M,Vaidehi N,Goddard WA,Nishi A,Hsieh-Wilson LC
Fri Sep 01 00:00:00 EDT 2006
Novel 70-kDa chondroitin sulfate/dermatan sulfate hybrid chains with a unique heterogeneous sulfation pattern from shark skin, which exhibit neuritogenic activity and binding activities for growth factors and neurotrophic factors.
The Journal of biological chemistry
Nandini CD,Itoh N,Sugahara K
Fri Feb 11 00:00:00 EST 2005
A functional dermatan sulfate epitope containing iduronate(2-O-sulfate)alpha1-3GalNAc(6-O-sulfate) disaccharide in the mouse brain: demonstration using a novel monoclonal antibody raised against dermatan sulfate of ascidian Ascidia nigra.
The Journal of biological chemistry
Bao X,Pavão MS,Dos Santos JC,Sugahara K
Fri Jun 17 00:00:00 EDT 2005
Chondroitin sulfate chains on syndecan-1 and syndecan-4 from normal murine mammary gland epithelial cells are structurally and functionally distinct and cooperate with heparan sulfate chains to bind growth factors. A novel function to control binding of midkine, pleiotrophin, and basic fibroblast growth factor.
The Journal of biological chemistry
Deepa SS,Yamada S,Zako M,Goldberger O,Sugahara K
Fri Sep 03 00:00:00 EDT 2004
Chondroitin sulfate/dermatan sulfate hybrid chains from embryonic pig brain, which contain a higher proportion of L-iduronic acid than those from adult pig brain, exhibit neuritogenic and growth factor binding activities.
The Journal of biological chemistry
Bao X,Nishimura S,Mikami T,Yamada S,Itoh N,Sugahara K
Fri Mar 12 00:00:00 EST 2004
Structural and functional characterization of oversulfated chondroitin sulfate/dermatan sulfate hybrid chains from the notochord of hagfish. Neuritogenic and binding activities for growth factors and neurotrophic factors.
The Journal of biological chemistry
Nandini CD,Mikami T,Ohta M,Itoh N,Akiyama-Nambu F,Sugahara K
Fri Dec 03 00:00:00 EST 2004
Specific molecular interactions of oversulfated chondroitin sulfate E with various heparin-binding growth factors. Implications as a physiological binding partner in the brain and other tissues.
The Journal of biological chemistry
Deepa SS,Umehara Y,Higashiyama S,Itoh N,Sugahara K
Fri Nov 15 00:00:00 EST 2002
