Product References
GDF-11 Protects the Traumatically Injured Spinal Cord by Suppressing Pyroptosis and Necroptosis via TFE3-Mediated Autophagy Augmentation.
Oxidative medicine and cellular longevity
Xu Y,Hu X,Li F,Zhang H,Lou J,Wang X,Wang H,Yin L,Ni W,Kong J,Wang X,Li Y,Zhou K,Xu H
Mon Feb 07 00:00:00 UTC 2022
Loss of Growth Differentiation Factor 11 Shortens Telomere Length by Downregulating Telomerase Activity.
Frontiers in physiology
Wang DX,Zhu XD,Ma XR,Wang LB,Dong ZJ,Lin RR,Cao YN,Zhao JW
120-11 was used in Cell Culture to establish the causality between growth differentiation factor 11 and the telomere maintenance unequivocally.
Thu Sep 21 00:00:00 UTC 2023
Similar sequences but dissimilar biological functions of GDF11 and myostatin.
Experimental & molecular medicine
Suh J,Lee YS
Thu Oct 01 00:00:00 UTC 2020
Similar sequences but dissimilar biological functions of GDF11 and myostatin.
Experimental & molecular medicine
Suh J,Lee YS
Thu Oct 01 00:00:00 UTC 2020
Systemic GDF11 stimulates the secretion of adiponectin and induces a calorie restriction-like phenotype in aged mice.
Aging cell
Katsimpardi L,Kuperwasser N,Camus C,Moigneu C,Chiche A,Tolle V,Li H,Kokovay E,Lledo PM
Wed Jan 01 00:00:00 UTC 2020
GDF11 enhances therapeutic efficacy of mesenchymal stem cells for myocardial infarction via YME1L-mediated OPA1 processing.
Stem cells translational medicine
Zhao Y,Zhu J,Zhang N,Liu Q,Wang Y,Hu X,Chen J,Zhu W,Yu H
Thu Oct 01 00:00:00 UTC 2020
Growth Differentiation Factor-11 Causes Neurotoxicity During Ischemia in vitro.
Frontiers in neurology
Sutherland BA,Hadley G,Alexopoulou Z,Lodge TA,Neuhaus AA,Couch Y,Kalajian N,Morten KJ,Buchan AM
120-11 was used in In vitro experiments to show that growth differentiation factor-11 (GDF-11) causes neuronal death following a period of glucose and oxygen deprivation, simulating stroke, in rats.
Tue Oct 06 00:00:00 UTC 2020
Aspirin promotes tenogenic differentiation of tendon stem cells and facilitates tendinopathy healing through regulating the GDF7/Smad1/5 signaling pathway.
Journal of cellular physiology
Wang Y,He G,Tang H,Shi Y,Zhu M,Kang X,Bian X,Lyu J,Zhou M,Yang M,Mu M,Chen W,Zhou B,Yuan C,Zhang J,Tang K
120-11 was used in In vitro experiments to find that aspirin promoted tenogenesis of TSCs.
Fri May 01 00:00:00 UTC 2020
Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice.
Scientific reports
Walker RG,Barrandon O,Poggioli T,Dagdeviren S,Carroll SH,Mills MJ,Mendello KR,Gomez Y,Loffredo FS,Pancoast JR,Macias-Trevino C,Marts C,LeClair KB,Noh HL,Kim T,Banks AS,Kim JK,Cohen DE,Wagers AJ,Melton DA,Lee RT
Thu Mar 12 00:00:00 UTC 2020
Oligodendrocyte Progenitor Cells Become Regionally Diverse and Heterogeneous with Age.
Neuron
Spitzer SO,Sitnikov S,Kamen Y,Evans KA,Kronenberg-Versteeg D,Dietmann S,de Faria O,Agathou S,Káradóttir RT
Wed Feb 06 00:00:00 UTC 2019
Growth differentiation factor 11 inhibits adipogenic differentiation by activating TGF-beta/Smad signalling pathway.
Cell proliferation
Luo H,Guo Y,Liu Y,Wang Y,Zheng R,Ban Y,Peng L,Yuan Q,Liu W
Mon Jul 01 00:00:00 UTC 2019
Recombinant growth differentiation factor 11 impairs fracture healing through inhibiting chondrocyte differentiation.
Annals of the New York Academy of Sciences
Zheng R,Xie L,Liu W,Guo Y,Wang Y,Wu Y,Liu Y,Luo H,Kang N,Yuan Q
120-11 was used in In vivo experiments to demonstrate that, rather than acting as a rejuvenating agent, rGDF11 impairs fracture healing by inhibiting chondrocyte differentiation and maturation.
Fri Mar 01 00:00:00 UTC 2019
Activin type II receptor signaling in cardiac aging and heart failure.
Science translational medicine
Roh JD,Hobson R,Chaudhari V,Quintero P,Yeri A,Benson M,Xiao C,Zlotoff D,Bezzerides V,Houstis N,Platt C,Damilano F,Lindman BR,Elmariah S,Biersmith M,Lee SJ,Seidman CE,Seidman JG,Gerszten RE,Lach-Trifilieff E,Glass DJ,Rosenzweig A
120-11 was used in In vivo experiments to suggest that increased activin/ActRII signaling links aging and HF pathobiology and that targeted inhibition of this catabolic pathway holds promise as a therapeutic strategy for multiple forms of HF.
Wed Mar 06 00:00:00 UTC 2019
Growth differentiation factor 11 ameliorates experimental colitis by inhibiting NLRP3 inflammasome activation.
American journal of physiology. Gastrointestinal and liver physiology
Wang L,Wang Y,Wang Z,Qi Y,Zong B,Liu M,Li X,Zhang X,Liu C,Cao R,Ma Y
Sat Dec 01 00:00:00 UTC 2018
Growth differentiation factor 11 ameliorates experimental colitis by inhibiting NLRP3 inflammasome activation.
American journal of physiology. Gastrointestinal and liver physiology
Wang L,Wang Y,Wang Z,Qi Y,Zong B,Liu M,Li X,Zhang X,Liu C,Cao R,Ma Y
Sat Dec 01 00:00:00 UTC 2018
Growth Differentiation Factor 11 treatment leads to neuronal and vascular improvements in the hippocampus of aged mice.
Scientific reports
Ozek C,Krolewski RC,Buchanan SM,Rubin LL
Fri Nov 23 00:00:00 UTC 2018
Growth Differentiation Factor 11 Promotes Neurovascular Recovery After Stroke in Mice.
Frontiers in cellular neuroscience
Lu L,Bai X,Cao Y,Luo H,Yang X,Kang L,Shi MJ,Fan W,Zhao BQ
120-11 was used in In vivo experiments to study the effects of growth differentiation factor 11 (GDF11) on brain repair during the recovery phase after stroke to demonstrate that GDF11 promotes neurogenesis and angiogenesis.
Thu Oct 01 00:00:00 UTC 2020
Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer.
Developmental cell
Bajikar SS,Wang CC,Borten MA,Pereira EJ,Atkins KA,Janes KA
120-11 was used in Dot blot to study the tumour-suppressive mode of action of growth-differentiation factor 11, and an unusual mechanism of its inactivation in triple negative breast cancer.
Mon Nov 20 00:00:00 UTC 2017
Is Growth Differentiation Factor 11 a Realistic Therapeutic for Aging-Dependent Muscle Defects?
Circulation research
Harper SC,Brack A,MacDonnell S,Franti M,Olwin BB,Bailey BA,Rudnicki MA,Houser SR
Fri Apr 01 00:00:00 UTC 2016
Is Growth Differentiation Factor 11 a Realistic Therapeutic for Aging-Dependent Muscle Defects?
Circulation research
Harper SC,Brack A,MacDonnell S,Franti M,Olwin BB,Bailey BA,Rudnicki MA,Houser SR
Fri Apr 01 00:00:00 UTC 2016
GDF11 decreases bone mass by stimulating osteoclastogenesis and inhibiting osteoblast differentiation.
Nature communications
Liu W,Zhou L,Zhou C,Zhang S,Jing J,Xie L,Sun N,Duan X,Jing W,Liang X,Zhao H,Ye L,Chen Q,Yuan Q
Thu Sep 22 00:00:00 UTC 2016
GDF11 decreases bone mass by stimulating osteoclastogenesis and inhibiting osteoblast differentiation.
Nature communications
Liu W,Zhou L,Zhou C,Zhang S,Jing J,Xie L,Sun N,Duan X,Jing W,Liang X,Zhao H,Ye L,Chen Q,Yuan Q
Thu Sep 22 00:00:00 UTC 2016
The use of carbon monoxide as a probe molecule in spectroscopic studies for determination of exposed gold sites on TiO2.
Physical chemistry chemical physics : PCCP
Lari GM,Nowicka E,Morgan DJ,Kondrat SA,Hutchings GJ
Mon Sep 21 00:00:00 UTC 2015
Deterministic HOX patterning in human pluripotent stem cell-derived neuroectoderm.
Stem cell reports
Lippmann ES,Williams CE,Ruhl DA,Estevez-Silva MC,Chapman ER,Coon JJ,Ashton RS
Tue Apr 14 00:00:00 UTC 2015
Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy.
Cell
Loffredo FS,Steinhauser ML,Jay SM,Gannon J,Pancoast JR,Yalamanchi P,Sinha M,Dall'Osso C,Khong D,Shadrach JL,Miller CM,Singer BS,Stewart A,Psychogios N,Gerszten RE,Hartigan AJ,Kim MJ,Serwold T,Wagers AJ,Lee RT
Thu May 09 00:00:00 UTC 2013
