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This peptide corresponds to 19 amino acids near the amino terminus of human NALP13.
PEP-1142 can be used as a blocking peptide with polyclonal antibody PA5-21028.
NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP13 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP13, it has been suggested that it may be implicated in the activation of proinflammatory caspases via inflammasomes.
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Protein Aliases: NACHT, leucine rich repeat and PYD containing 13; NACHT, LRR and PYD containing protein 13; NACHT, LRR and PYD domains-containing protein 13; NLR family, pyrin domain containing 13; Nucleotide-binding oligomerization domain protein 14; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13
Gene Aliases: CLR19.7; NALP13; NLRP13; NOD14; PAN13
UniProt ID: (Human) Q86W25
Entrez Gene ID: (Human) 126204
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