Invitrogen

Human NALP8 Synthetic Peptide

Product Details

PEP-1138

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

Blocking Assay (BLOCK)

Assay-dependent

Product Specifications

Species Reactivity

Human

Class

Synthetic

Type

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

purified

Storage buffer

PBS, pH 7.2, with 0.1% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Dry ice

Product Specific Information

This peptide corresponds to 16 amino acids near the amino terminus of human NALP8.

PEP-1138 can be used as a blocking peptide with polyclonal antibody PA5-21024.

Target Information

NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: NACHT, leucine rich repeat and PYD containing 8; NACHT, LRR and PYD containing protein 8; NACHT, LRR and PYD domains-containing protein 8; NLR family, pyrin domain containing 8; Nucleotide-binding oligomerization domain protein 16; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 8; PYRIN and NACHT-containing protein 4