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Invitrogen
Human NEK6, GST Tag Recombinant Protein
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Product Details
A31511
Product Specifications
Species
Human
Expression System
Insect cells
Amino acid sequence
Full length
Tag
GST-tag
Molecular weight
62.4 kDa
Class
Recombinant
Type
Protein
Conjugate
Form
Liquid
Concentration
See Label
Purification
purified
Storage buffer
50mM tris HCl, pH 7.5, with 150mM NaCl, 0.1mM PMSF, 0.1mM EDTA, 0.25mM DTT, 25% glycerol, 10mM glutathione
Contains
no preservative
Storage conditions
-80°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Dry ice
Product Specific Information
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
This purified recombinant full-length protein can be used in a number of different applications, but it has been specifically validated for use with our Z'-LYTE™ assay technology to identify novel kinase inhibitors. NEK6 is also available in our SelectScreen™ Kinase Profiling Service.
• Validated for use with the Z'-LYTE assay technology
• Available in multiple pack sizes for convenient use
• Also available in our SelectSceen Kinase Profiling Service
Protein Form: Full Length, Recombinant, Active
The gene accession number for NEK6 is NP_055212.2.
Target Information
NEK6 kinase is a member of the NEK family. NEK6 is a serine/threonine kinase that controls the initiation of mitosis and is required for the metaphase-anaphase transition. The Aspergillus nidulans 'never in mitosis A' (NIMA) gene encodes a serine/threonine kinase that controls initiation of mitosis. NIMA-related kinases (NEKs) are a group of protein kinases that are homologous to NIMA. Evidence suggests that NEKs perform functions similar to those of NIMA. NEK6 encodes a NEK type protein kinase, which contains a C-terminal NIMA-like catalytic domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Never in mitosis A-related kinase 6; NIMA (never in mitosis gene a)-related kinase 6; NIMA-related kinase 6; NimA-related protein kinase 6; Protein kinase SID6-1512; putative serine-threonine protein kinase; RP11-101K10.6; Serine/threonine-protein kinase Nek6; SID
Gene Aliases: NEK6; SID6-1512
UniProt ID: (Human) Q9HC98
Entrez Gene ID: (Human) 10783
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