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          • Proteins & Peptides ›
          • TrkA Proteins

          Invitrogen

          Human NTRK1 (TRKA), His Tag Recombinant Protein

          View all (2) TrkA proteins

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          Cite Human NTRK1 (TRKA), His Tag Recombinant Protein

          Product Details

          PR4672D

          Applications
          Tested Dilution
          Publications

          Kinase Assay (KA)

          Assay-dependent
          -
          Product Specifications

          Species

          Human

          Expression System

          Insect cells

          Amino acid sequence

          441-796

          Tag

          His-tag

          Molecular weight

          42.8 kDa

          Class

          Recombinant

          Type

          Protein

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          See Label

          Purification

          purified

          Storage buffer

          50mM tris, pH 7.5, with 50% glycerol, 0.05% Triton X-100, 0.2mM EDTA, 100mM NaCl, 5mM DTT

          Contains

          no preservative

          Storage conditions

          -80°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Dry ice

          Product Specific Information

          For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.

          Protein Form: Recombinant, Cytoplasmic

          Target Information

          NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: DKFZp781I14186; EC 2.7.10.1; gp140trk; High affinity nerve growth factor receptor; kinase TrkA; Neurotrophic tyrosine kinase receptor type 1; neurotrophic tyrosine kinase, receptor, type 1; Oncogene TRK; p140-TrkA; Trk-A; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A

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          Gene Aliases: MTC; NTRK1; p140-TrkA; TRK; Trk-A; TRK1; TRKA

          View more View less

          UniProt ID: (Human) P04629

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          Entrez Gene ID: (Human) 4914

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          It has to be done as per old AB suggested Products section.
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