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Product Details
PEP-0483
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Dry ice
Product Specific Information
This peptide corresponds to 23 amino acids near the amino terminus of human Neurotrypsin
PEP-0483 can be used as a blocking peptide with polyclonal antibody PA5-20363.
Target Information
Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: brain-specific serine protease 3; Leydin; Motopsin; Neurotrypsin; protease, serine, 12 (neurotrypsin, motopsin); Serine protease 12
Gene Aliases: BSSP-3; BSSP3; MRT1; PRSS12
UniProt ID: (Human) P56730
Entrez Gene ID: (Human) 8492
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