Product References
Repeated intravenous administration of hiPSC-MSCs enhance the efficacy of cell-based therapy in tissue regeneration.
Communications biology
Sun SJ,Li F,Dong M,Liang WH,Lai WH,Ho WI,Wei R,Huang Y,Liao SY,Tse HF
100-00AB was used in Sample Preparation (FC/FACS) to demonstrate whether therapeutic efficacy can be improved by combination of repeated intravenous administration and local transplantation of human induced pluripotential stem cell derived MSCs (hiPSC-MSCs).
Thu Aug 25 00:00:00 EDT 2022
Context-dependent tumor-suppressive BMP signaling in diffuse intrinsic pontine glioma regulates stemness through epigenetic regulation of CXXC5.
Nature cancer
Sun Y,Yan K,Wang Y,Xu C,Wang D,Zhou W,Guo S,Han Y,Tang L,Shao Y,Shan S,Zhang QC,Tang Y,Zhang L,Xi Q
100-00AB was used in Cell Culture to show how BMP signaling impacts diffuse intrinsic pontine glioma (DIPG) and identifies the potent antitumor efficacy of Dacinostat for DIPG.
Thu Sep 01 00:00:00 EDT 2022
RAB31 marks and controls an ESCRT-independent exosome pathway.
Cell research
Wei D,Zhan W,Gao Y,Huang L,Gong R,Wang W,Zhang R,Wu Y,Gao S,Kang T
Mon Feb 01 00:00:00 EST 2021
Alcohol-abuse drug disulfiram targets pediatric glioma via MLL degradation.
Cell death & disease
Meier S,Cantilena S,Niklison Chirou MV,Anderson J,Hargrave D,Salomoni P,de Boer J,Michod D
Wed Aug 11 00:00:00 EDT 2021
A non-invasive method to generate induced pluripotent stem cells from primate urine.
Scientific reports
Geuder J,Wange LE,Janjic A,Radmer J,Janssen P,Bagnoli JW,Müller S,Kaul A,Ohnuki M,Enard W
Wed Feb 10 00:00:00 EST 2021
Chondroitin sulfate synthase 1 enhances proliferation of glioblastoma by modulating PDGFRA stability.
Oncogenesis
Liao WC,Liao CK,Tseng TJ,Ho YJ,Chen YR,Lin KH,Lai TJ,Lan CT,Wei KC,Liu CH
Tue Feb 04 00:00:00 EST 2020
MiRNA-137-mediated modulation of mitochondrial dynamics regulates human neural stem cell fate.
Stem cells (Dayton, Ohio)
Channakkar AS,Singh T,Pattnaik B,Gupta K,Seth P,Adlakha YK
Fri May 01 00:00:00 EDT 2020
Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming.
Cell reports
Yan P,Liu Z,Song M,Wu Z,Xu W,Li K,Ji Q,Wang S,Liu X,Yan K,Esteban CR,Ci W,Belmonte JCI,Xie W,Ren J,Zhang W,Sun Q,Qu J,Liu GH
100-00AB was used in Cell Culture to study the homeostasis of DNA:RNA hybrid regulation of chromatin and genome organization by characterizing R-loops, DNA methylation, histone modifications, and chromatin accessibility in pluripotent cells and their lineage-differentiated derivatives.
Tue Jul 07 00:00:00 EDT 2020
Oncogenic mutant RAS signaling activity is rescaled by the ERK/MAPK pathway.
Molecular systems biology
Gillies TE,Pargett M,Silva JM,Teragawa CK,McCormick F,Albeck JG
Thu Oct 01 00:00:00 EDT 2020
Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction.
Scientific reports
Nzou G,Wicks RT,VanOstrand NR,Mekky GA,Seale SA,El-Taibany A,Wicks EE,Nechtman CM,Marrotte EJ,Makani VS,Murphy SV,Seeds MC,Jackson JD,Atala AJ
Wed Jun 17 00:00:00 EDT 2020
Self-Assembling Peptide Hydrogel Matrices Improve the Neurotrophic Potential of Human Adipose-Derived Stem Cells.
Advanced healthcare materials
Faroni A,Workman VL,Saiani A,Reid AJ
Sun Sep 01 00:00:00 EDT 2019
Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB.
Oncogenesis
Mahjour F,Dambal V,Shrestha N,Singh V,Noonan V,Kantarci A,Trackman PC
Mon May 13 00:00:00 EDT 2019
Cell Type-Specific Interferon-γ-mediated Antagonism of KSHV Lytic Replication.
Scientific reports
Park MK,Cho H,Roh SW,Kim SJ,Myoung J
Wed Feb 20 00:00:00 EST 2019
Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca2+ flickers.
Communications biology
Ellefsen KL,Holt JR,Chang AC,Nourse JL,Arulmoli J,Mekhdjian AH,Abuwarda H,Tombola F,Flanagan LA,Dunn AR,Parker I,Pathak MM
Mon Apr 20 00:00:00 EDT 2020
Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca2+ flickers.
Communications biology
Ellefsen KL,Holt JR,Chang AC,Nourse JL,Arulmoli J,Mekhdjian AH,Abuwarda H,Tombola F,Flanagan LA,Dunn AR,Parker I,Pathak MM
Mon Apr 20 00:00:00 EDT 2020
Modelling Duchenne muscular dystrophy in MYOD1-converted urine-derived cells treated with 3-deazaneplanocin A hydrochloride.
Scientific reports
Takizawa H,Hara Y,Mizobe Y,Ohno T,Suzuki S,Inoue K,Takeshita E,Shimizu-Motohashi Y,Ishiyama A,Hoshino M,Komaki H,Takeda S,Aoki Y
Thu Mar 07 00:00:00 EST 2019
The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis.
Cell
de la Torre-Ubieta L,Stein JL,Won H,Opland CK,Liang D,Lu D,Geschwind DH
Thu Jan 11 00:00:00 EST 2018
Intrinsic Immunity Shapes Viral Resistance of Stem Cells.
Cell
Wu X,Dao Thi VL,Huang Y,Billerbeck E,Saha D,Hoffmann HH,Wang Y,Silva LAV,Sarbanes S,Sun T,Andrus L,Yu Y,Quirk C,Li M,MacDonald MR,Schneider WM,An X,Rosenberg BR,Rice CM
Thu Jan 25 00:00:00 EST 2018
Neuroprotective Effects of Human Mesenchymal Stem Cells and Platelet-Derived Growth Factor on Human Retinal Ganglion Cells.
Stem cells (Dayton, Ohio)
Osborne A,Sanderson J,Martin KR
Mon Jan 01 00:00:00 EST 2018
PDGF-mediated mesenchymal transformation renders endothelial resistance to anti-VEGF treatment in glioblastoma.
Nature communications
Liu T,Ma W,Xu H,Huang M,Zhang D,He Z,Zhang L,Brem S,O'Rourke DM,Gong Y,Mou Y,Zhang Z,Fan Y
Mon Aug 27 00:00:00 EDT 2018
Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling.
Scientific reports
Nzou G,Wicks RT,Wicks EE,Seale SA,Sane CH,Chen A,Murphy SV,Jackson JD,Atala AJ
Wed May 09 00:00:00 EDT 2018
c-Abl-TWIST1 Epigenetically Dysregulate Inflammatory Responses during Mycobacterial Infection by Co-Regulating Bone Morphogenesis Protein and miR27a.
Frontiers in immunology
Mahadik K,Prakhar P,Rajmani RS,Singh A,Balaji KN
100-00AB was used in In vitro experiments to suggest molecular mechanisms of host pathways hijacked by mycobacteria and expand our understanding of c-Abl inhibitors in potentiating innate immune responses.
Thu Feb 28 00:00:00 EST 2019
The PDGFRα-laminin B1-keratin 19 cascade drives tumor progression at the invasive front of human hepatocellular carcinoma.
Oncogene
Govaere O,Petz M,Wouters J,Vandewynckel YP,Scott EJ,Topal B,Nevens F,Verslype C,Anstee QM,Van Vlierberghe H,Mikulits W,Roskams T
Thu Nov 23 00:00:00 EST 2017
The PDGFRα-laminin B1-keratin 19 cascade drives tumor progression at the invasive front of human hepatocellular carcinoma.
Oncogene
Govaere O,Petz M,Wouters J,Vandewynckel YP,Scott EJ,Topal B,Nevens F,Verslype C,Anstee QM,Van Vlierberghe H,Mikulits W,Roskams T
Thu Nov 23 00:00:00 EST 2017
The PDGFRα-laminin B1-keratin 19 cascade drives tumor progression at the invasive front of human hepatocellular carcinoma.
Oncogene
Govaere O,Petz M,Wouters J,Vandewynckel YP,Scott EJ,Topal B,Nevens F,Verslype C,Anstee QM,Van Vlierberghe H,Mikulits W,Roskams T
Thu Nov 23 00:00:00 EST 2017
iPSC-derived mesenchymal stem cells exert SCF-dependent recovery of cigarette smoke-induced apoptosis/proliferation imbalance in airway cells.
Journal of cellular and molecular medicine
Li X,Zhang Y,Liang Y,Cui Y,Yeung SC,Ip MS,Tse HF,Lian Q,Mak JC
Wed Feb 01 00:00:00 EST 2017
Human Primary Bone Marrow Mesenchymal Stromal Cells and Their in vitro Progenies Display Distinct Transcriptional Profile Signatures.
Scientific reports
Ghazanfari R,Zacharaki D,Li H,Ching Lim H,Soneji S,Scheding S
Mon Sep 04 00:00:00 EDT 2017
Platelet-Derived Growth Factor Preserves Retinal Synapses in a Rat Model of Ocular Hypertension.
Investigative ophthalmology & visual science
Chong RS,Osborne A,Conceição R,Martin KR
100-00AB was used in In vivo experiments to investigate PDGF effects on inflammation in retinal synapses.
Tue Mar 01 00:00:00 EST 2016
Modeling familial cancer with induced pluripotent stem cells.
Cell
Lee DF,Su J,Kim HS,Chang B,Papatsenko D,Zhao R,Yuan Y,Gingold J,Xia W,Darr H,Mirzayans R,Hung MC,Schaniel C,Lemischka IR
Thu Apr 09 00:00:00 EDT 2015
Leukemia propagating cells rebuild an evolving niche in response to therapy.
Cancer cell
Duan CW,Shi J,Chen J,Wang B,Yu YH,Qin X,Zhou XC,Cai YJ,Li ZQ,Zhang F,Yin MZ,Tao Y,Mi JQ,Li LH,Enver T,Chen GQ,Hong DL
Mon Jun 16 00:00:00 EDT 2014
Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells.
Proceedings of the National Academy of Sciences of the United States of America
Pathak MM,Nourse JL,Tran T,Hwe J,Arulmoli J,Le DT,Bernardis E,Flanagan LA,Tombola F
Tue Nov 11 00:00:00 EST 2014
Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix.
Proceedings of the National Academy of Sciences of the United States of America
Martino MM,Briquez PS,Ranga A,Lutolf MP,Hubbell JA
Tue Mar 19 00:00:00 EDT 2013
Spindle shaped human mesenchymal stem/stromal cells from amniotic fluid promote neovascularization.
PloS one
Roubelakis MG,Tsaknakis G,Pappa KI,Anagnou NP,Watt SM
Fri Sep 06 00:00:00 EDT 2013
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.
Nature
Wilson TR,Fridlyand J,Yan Y,Penuel E,Burton L,Chan E,Peng J,Lin E,Wang Y,Sosman J,Ribas A,Li J,Moffat J,Sutherlin DP,Koeppen H,Merchant M,Neve R,Settleman J
Thu Jul 26 00:00:00 EDT 2012
PDGF enhances IRES-mediated translation of Laminin B1 by cytoplasmic accumulation of La during epithelial to mesenchymal transition.
Nucleic acids research
Petz M,Them NC,Huber H,Mikulits W
Mon Oct 01 00:00:00 EDT 2012
Chemokine (C-C motif) ligand 2 mediates direct and indirect fibrotic responses in human and murine cultured fibrocytes.
Fibrogenesis & tissue repair
Ekert JE,Murray LA,Das AM,Sheng H,Giles-Komar J,Rycyzyn MA
Wed Oct 19 00:00:00 EDT 2011
Chemokine (C-C motif) ligand 2 mediates direct and indirect fibrotic responses in human and murine cultured fibrocytes.
Fibrogenesis & tissue repair
Ekert JE,Murray LA,Das AM,Sheng H,Giles-Komar J,Rycyzyn MA
Wed Oct 19 00:00:00 EDT 2011
Platelet-derived growth factor differentially regulates the expression and post-translational modification of versican by arterial smooth muscle cells through distinct protein kinase C and extracellular signal-regulated kinase pathways.
The Journal of biological chemistry
Cardoso LE,Little PJ,Ballinger ML,Chan CK,Braun KR,Potter-Perigo S,Bornfeldt KE,Kinsella MG,Wight TN
Fri Mar 05 00:00:00 EST 2010
Endogenous Wnt signaling maintains neural progenitor cell potency.
Stem cells (Dayton, Ohio)
Wexler EM,Paucer A,Kornblum HI,Palmer TD,Geschwind DH
Fri May 01 00:00:00 EDT 2009
Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1.
The Journal of cell biology
Blagoveshchenskaya A,Cheong FY,Rohde HM,Glover G,Knödler A,Nicolson T,Boehmelt G,Mayinger P
Mon Feb 25 00:00:00 EST 2008
Derivation of clinically compliant MSCs from CD105+, CD24- differentiated human ESCs.
Stem cells (Dayton, Ohio)
Lian Q,Lye E,Suan Yeo K,Khia Way Tan E,Salto-Tellez M,Liu TM,Palanisamy N,El Oakley RM,Lee EH,Lim B,Lim SK
Thu Feb 01 00:00:00 EST 2007
The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities.
Stem cells (Dayton, Ohio)
Ponte AL,Marais E,Gallay N,Langonné A,Delorme B,Hérault O,Charbord P,Domenech J
Sun Jul 01 00:00:00 EDT 2007
Production of a novel fibroblast-populated platelet matrix cocultured with keratinocytes.
Tissue engineering
Schuster KM,Martens M,Goldenberg M,Tai C,Strande L,Hewitt CW
Sun Jul 01 00:00:00 EDT 2007
Exploring the regulation of human neural precursor cell differentiation using arrays of signaling microenvironments.
Molecular systems biology
Soen Y,Mori A,Palmer TD,Brown PO
Fri Sep 29 00:00:00 EDT 2006
Essential roles of sphingosine-1-phosphate and platelet-derived growth factor in the maintenance of human embryonic stem cells.
Stem cells (Dayton, Ohio)
Pébay A,Wong RC,Pitson SM,Wolvetang EJ,Peh GS,Filipczyk A,Koh KL,Tellis I,Nguyen LT,Pera MF
Fri Mar 17 00:00:00 EST 2006
Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation. Contributions of Src- and receptor-tyrosine kinases.
The Journal of biological chemistry
Sommer U,Schmid C,Sobota RM,Lehmann U,Stevenson NJ,Johnston JA,Schaper F,Heinrich PC,Haan S
Fri Sep 09 00:00:00 EDT 2005
Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation. Contributions of Src- and receptor-tyrosine kinases.
The Journal of biological chemistry
Sommer U,Schmid C,Sobota RM,Lehmann U,Stevenson NJ,Johnston JA,Schaper F,Heinrich PC,Haan S
Fri Sep 09 00:00:00 EDT 2005
Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation. Contributions of Src- and receptor-tyrosine kinases.
The Journal of biological chemistry
Sommer U,Schmid C,Sobota RM,Lehmann U,Stevenson NJ,Johnston JA,Schaper F,Heinrich PC,Haan S
Fri Sep 09 00:00:00 EDT 2005
The Egr-1 gene is induced by epidermal growth factor in ECV304 cells and primary endothelial cells.
American journal of physiology. Cell physiology
Tsai JC,Liu L,Guan J,Aird WC
Wed Nov 01 00:00:00 EST 2000
The Egr-1 gene is induced by epidermal growth factor in ECV304 cells and primary endothelial cells.
American journal of physiology. Cell physiology
Tsai JC,Liu L,Guan J,Aird WC
Wed Nov 01 00:00:00 EST 2000
EGF inhibits muscarinic receptor-mediated calcium signaling in a human salivary cell line.
American journal of physiology. Cell physiology
Zhang BX,Yeh CK,Hymer TK,Lifschitz MD,Katz MS
Sun Oct 01 00:00:00 EDT 2000