Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (81%), Rat (81%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57789. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
PTGR1 encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 15-oxoprostaglandin 13-reductase; D3T-inducible gene 1 protein; Dithiolethione-inducible gene 1 protein; FLJ99229; Leukotriene B4 12-hydroxydehydrogenase; MGC34943; NAD(P)H-dependent alkenal/one oxidoreductase; NADP-dependent leukotriene B4 12-hydroxydehydrogenase; PRG-1; Prostaglandin reductase 1; zinc binding alcohol dehydrogenase domain containing 3
Gene Aliases: LTB4DH; PGR1; PTGR1; ZADH3
UniProt ID: (Human) Q14914
Entrez Gene ID: (Human) 22949
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