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Product Details
PEP-137
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
purified
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
PEP-137 is an 18 amino acid synthetic peptide whose sequences are derived from human RanBP2 protein. The sequence of this peptide is (amino to carboxy terminus): M (1)-R-R-S-K-A-D-V-E-R-Y-I-A-S-V-Q-G-S (18)-C
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human RanBP2, catalog # PA1-082. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
Target Information
RanBP2 interacts with the small GTP-binding protein Ran and forms a large multiprotein complex involved in many biological processes such as mRNA processing, nuclear transport, cell cycle control and postmitotic nuclear reassembly. The protein is identified by western blotting as an apparent molecular mass of 360 kD. It is involved in nucleation of microtubule and control of cell growth by interacting with many protein factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 358 kDa nucleoporin; acute necrotizing encephalopathy 1 (autosomal dominant); E3 SUMO-protein ligase RanBP2; Nuclear pore complex protein Nup358; nucleoporin 358; Nucleoporin Nup358; P270; Ran-binding protein 2; RanBP2; RBP2; transformation-related protein 2
Gene Aliases: ADANE; ANE1; IIAE3; NUP358; RANBP2; TRP1; TRP2
UniProt ID: (Human) P49792
Entrez Gene ID: (Human) 5903
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