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Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56966. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
DSCR1L2 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A, and may play a role during central nervous system development. Highest expression occurs in heart, skeletal muscle kidney, liver and peripheral blood leukocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Calcipressin 3; Calcipressin-3; Down syndrome candidate region 1-like 2; Down syndrome candidate region 1-like protein 2; Down syndrome critical region gene 1-like 2; MCIP3; Myocyte-enriched calcineurin-interacting protein 3; Regulator of calcineurin 3; regulator of calcineurin 3 isoform 1b,2
Gene Aliases: DSCR1L2; hRCN3; MCIP3; RCAN3; RCN3
UniProt ID: (Human) Q9UKA8
Entrez Gene ID: (Human) 11123
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