Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (59%), Rat (59%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58654. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: RBPJ-interacting and tubulin-associated protein; RBPJ-interacting and tubulin-associated protein 1
Gene Aliases: C12orf52; PSEC0043; RITA; RITA1
UniProt ID: (Human) Q96K30
Entrez Gene ID: (Human) 84934
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