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Invitrogen
Human RUNX3 (aa 205-221) Synthetic Peptide
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Product Details
PEP-292
Product Specifications
Class
Synthetic
Type
Peptide
Conjugate
Form
Lyophilized
Amount
50 µg
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Dry ice
Product Specific Information
PEP-292 is a 17 amino acid synthetic peptide whose sequence corresponds to residues 205-221 of human RUNX3. The sequence of this peptide is (amino to carboxyl terminus): T (205) K P F P D R F G D L E R L R M (221)R.
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, RUNX3, catalog # PA1-318. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Target Information
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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