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Product Details
130-15-100UG
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Published species
Rat
Expression System
E. coli
Amino acid sequence
A-Chain: QLYSALANKC CHVGCTKRSL ARFC B-Chain: DSWMEEVIKL CGRELVRAQI AICGMSTWS
Molecular weight
6 kDa
Class
Recombinant
Type
Protein
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Conjugate
Form
Lyophilized
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
Recombinant Human Relaxin-2 is a non-glycosylated, 6.0 kDa, disulfide-linked, heterodimeric protein consisting of a 24 amino acid A-chain, and a 29 amino acid B-chain.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
Relaxin 1 (also referred to as Relaxin or RLXH1) is a peptide hormone produced by the corpora lutea of the ovary during pregnancy in many mammalian species, including human. The secretion of the hormone into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. By inhibiting uterine contractions, Relaxin 1 may influence the timing of parturition. Like insulin, Relaxin 1 consists of two peptide chains, A and B, covalently linked by disulfide bonds. By further analogy to insulin, the two peptides are synthesized as a single-chain precursor polypeptide with the B chain at the amino-terminus. The gene that encodes the human Relaxin 1 protein maps to chromosome 9. Relaxin 2, a related protein, is selectively expressed in the ovary during pregnancy. The gene that encodes the human Relaxin 2 protein also maps to chromosome 9.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: H2-preprorelaxin; Prorelaxin H2; relaxin H2; relaxin, ovarian, of pregnancy; RLX H2-RLX
Gene Aliases: bA12D24.1.1; bA12D24.1.2; H2; H2-RLX; RLN2; RLXH2
UniProt ID: (Human) P04090
Entrez Gene ID: (Human) 6019
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