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Invitrogen
Human SIRPB1 Control Fragment Recombinant Protein
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Product Details
RP-100868
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
VSKSYALEISAHQKEHGSDITHEPALAPTAPL
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (34%), Rat (34%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83866. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
SIRP beta 1 is a type I transmembrane protein belonging to the SIRP family within the Ig superfamily. Members of this family are characterized by an extracellular region containing a V-set Ig domain with a J-like sequence and two C1-set Ig domains. Unlike SIRP alpha that has cytoplasmic ITIM domains, SIRP beta 1 possesses positively charged residues that allow association with ITAM motif-containing adaptor molecules. SIRP beta 1 is expressed on cells of monocyte, macrophage or dendritic lineages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD172 antigen-like family member B; CD172b; CD172b antigen; DKFZp686A05192; signal-regulatory protein beta 1; Signal-regulatory protein beta-1; Signal-regulatory protein beta-1 isoform 3; SIRP BETA 1; SIRP-beta-1; SIRP-beta-1 isoform 3
Gene Aliases: CD172b; SIRP-BETA-1; SIRPB1
UniProt ID: (Human) O00241
Entrez Gene ID: (Human) 10326
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