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Invitrogen
Human SLC39A2 Synthetic Peptide
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Product Details
PEP-1181
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Amount
50 µg
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
This peptide corresponds to 17 amino acids near the amino terminus of human ZIP2.
PEP-1181 can be used as a blocking peptide with polyclonal antibody PA5-21067.
Target Information
The zinc transporter ZIP2, also known as SLC39A2, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP3, ZIP2-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 6A1; Eti-1; MGC119190; solute carrier family 39 (zinc transporter), member 2; Solute carrier family 39 member 2; unnamed protein product; zinc transporter 2; Zinc transporter ZIP2; zinc uptake transporter 2; ZIP-2; Zrt- and Irt-like protein 2; ZRT/IRT-like protein 2
Gene Aliases: 6A1; ETI-1; SLC39A2; ZIP-2; ZIP2
UniProt ID: (Human) Q9NP94
Entrez Gene ID: (Human) 29986
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