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Invitrogen
Human SLC39A7 (aa 30-91) Control Fragment Recombinant Protein
Product Details
RP-101736
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
GHDDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHG
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (75%), Rat (75%).^M
^M
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62893. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The zinc transporter ZIP7, also known as SLC39A7, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP7 was initially identified while characterizing genes in the major histocompatibility complex on chromosome 17. ZIP7 mRNA is abundantly and widely expressed and the protein localizes to the Golgi apparatus. It functions to transport intracellular zinc from the Golgi apparatus to the cytoplasm of the cell. ZIP7 expression is expressed by zinc. ZIP7 has been suggested to act a hub for tyrosine kinase activation and may thus be a potential therapeutic target for diseases such as cancer where prevention of tyrosine kinase activation would be advantageous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DADB-100D22.3; Histidine-rich membrane protein Ke4; HLA class II region expressed gene KE4; Ke4 gene; Ke4 gene, mouse, human homolog of; Really interesting new gene 5 protein; solute carrier family 39 (zinc transporter), member 7; Solute carrier family 39 member 7; Zinc transporter SLC39A7; ZIP7; Zrt-, Irt-like protein 7
Gene Aliases: D6S115E; D6S2244E; H2-KE4; HKE4; KE4; RING5; SLC39A7; ZIP7
UniProt ID: (Human) Q92504
Entrez Gene ID: (Human) 7922
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