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Invitrogen
Human TSPY1 Synthetic Peptide
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Product Details
PEP-1525
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Amount
50 µg
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
This peptide corresponds to 20 amino acids near the carboxy terminus of human TSPY1L.
PEP-1525 can be used as a blocking peptide with polyclonal antibody PA5-34483.
Target Information
Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cancer/testis antigen 78; CT78; testicular protein; testis specific protein, Y-linked; Testis-specific Y-encoded protein 1; TSPY1L; TSPY1S
Gene Aliases: CT78; DYS14; pJA923; TSPY; TSPY1
UniProt ID: (Human) Q01534
Entrez Gene ID: (Human) 7258
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