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Invitrogen
Human ULK2 Synthetic Peptide
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Product Details
PEP-1586
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
This peptide corresponds to 17 amino acids near the center of human ULK2.
PEP-1586 can be used as a blocking peptide with polyclonal antibody PA5-34543. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37°C.
Target Information
ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC:2.7.11.1; Serine/threonine-protein kinase ULK2; Unc-51-like kinase 2
Gene Aliases: ATG1B; KIAA0623; ULK2; Unc51.2
UniProt ID: (Human) Q8IYT8
Entrez Gene ID: (Human) 9706
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