Search
Invitrogen
Human VDAC (aa 185-197) Synthetic Peptide
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PEP-082
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
50 µg
Purification
purified
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
PEP-082 is a 14 amino acid synthetic peptide whose sequence corresponds to amino acid residues 185-197 of human VDAC1 protein with an N-terminal cysteine added for carrier protein conjugation. The sequence of this peptide is (amino to carboxy terminus): C N (185) D G T E F G G S I Y Q K (197)
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human VDAC 1, catalog # PA1-954A. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
Target Information
Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins belonging to the eukaryotic mitochondrial porins. It was discovered in the mitochondrial outer membrane. It also is expressed in the plasma membrane. At least three different VDAC genes have been identified in vertebrates. VDAC proteins are known to play an essential role in cellular metabolism and in the early stages of apoptosis. For example, VDAC constitutes a major pathway by which metabolites such as ADP/ATP, succinate and citrate are exchanged between the cytosol and mitochondria. And VDAC1 in the plasma membrane establishes a novel level of apoptosis regulation putatively via its redox activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 1; ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 2; ATVDAC1; ATVDAC2; F2G14.210; HSR2; hVDAC1; K9I9.6; K9I9_6; MGC111064; Mitochondrial Porin; Non-selective voltage-gated ion channel VDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; PORIN-31-HL; sperm binding protein 1a; T22N4.9; T22N4_9; unnamed protein product; VD; VDAC-1; VDAC1; VDAC2; Voltage-dependent anion-selective channel protein 1
Gene Aliases: PORIN; VDAC; VDAC-1; VDAC1
UniProt ID: (Human) P21796
Entrez Gene ID: (Human) 7416
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support