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Human VEGF-C Recombinant Protein, PeproTech®
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Product Details
100-20CD-20UG
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Published species
Human,
Mouse,
Rat
Expression System
HEK293 cells
Amino acid sequence
AHYNTEILKS IDNEWRKTQC MPREVCIDVG KEFGVATNTF FKPPCVSVYR CGGCCNSEGL QCMNTSTSYL SKTLFEITVP LSQGPKPVTI SFANHTSCRC MSKLDVYRQV HSIIRR
Molecular weight
26.2 kDa
Class
Recombinant
Type
Protein
Purity
≥ 95% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
Determined by its ability to stimulate the proliferation of human microvascular endothelial cells (HMVEC) in low serum conditions.
Conjugate
Form
Lyophilized
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
Recombinant Human VEGF-C is a disulfide-linked homodimeric protein consisting of two 13.5 kDa polypeptide chains of 116 amino acid residues. Due to glycosylation, the protein migrates as a 30.0-33.0 kDa band by SDS-PAGE analysis under non-reducing conditions.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Flt4 ligand; FLT4 ligand DHM; Flt4-L; unnamed protein product; Vascular endothelial growth factor C; Vascular endothelial growth factor-related protein; VEGF-C; VEGF3; VEGFC; VRP
Gene Aliases: Flt4-L; LMPH1D; LMPHM4; VEGFC; VRP
UniProt ID: (Human) P49767
Entrez Gene ID: (Human) 7424
Disclaimer
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