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Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55611. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: h-VPS45; HGNC:14579; hlVps45; leucocyte vacuolar protein sorting 45; RP11-458I7.2; vacuolar protein sorting 45A; Vacuolar protein sorting-associated protein 45
Gene Aliases: H1; H1VPS45; SCN5; VPS45; VPS45A; VPS45B; VPS54A; VSP45; VSP45A
UniProt ID: (Human) Q9NRW7
Entrez Gene ID: (Human) 11311
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