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Product Details
PEP-1100
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Dry ice
Product Specific Information
This peptide corresponds to 14 amino acids near the carboxy terminus of human ZC3HAV1.
PEP-1100 can be used as a blocking peptide with polyclonal antibody PA5-20986.
Target Information
The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosyltransferase diphtheria toxin-like 13; ARTD13; Inactive Poly [ADP-ribose] polymerase 13; PARP13; ZAP; Zinc finger antiviral protein; Zinc finger CCCH domain-containing protein 2; Zinc finger CCCH-type antiviral protein 1; zinc finger CCCH-type, antiviral 1
Gene Aliases: ARTD13; FLB6421; PARP13; PRO1677; ZAP; ZC3H2; ZC3HAV1; ZC3HDC2
UniProt ID: (Human) Q7Z2W4
Entrez Gene ID: (Human) 56829
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