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Invitrogen
Human ZMPSTE24 (aa 46-78) Control Fragment Recombinant Protein
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Product Details
RP-89233
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
KTTTHVPPELGQIMDSETFEKSRLYQLDKSTFS
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-110715. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAAX prenyl protease 1 homolog; FACE-1; Farnesylated proteins-converting enzyme 1; FLJ14968; Prenyl protein-specific endoprotease 1; zinc metallopeptidase STE24 homolog; Zinc metalloproteinase Ste24 homolog
Gene Aliases: FACE-1; FACE1; HGPS; PRO1; STE24; Ste24p; ZMPSTE24
UniProt ID: (Human) O75844
Entrez Gene ID: (Human) 10269
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