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Invitrogen
Human ZNF609 (aa 54-143) Control Fragment Recombinant Protein
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Product Details
RP-98149
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
SKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGGLVAAIAPKGS
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59314. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The ZNF609 gene encodes zinc finger protein 609, which functions as a transcriptional regulator involved in the modulation of gene expression during development and cellular differentiation. ZNF609 contains zinc finger domains, which enable it to bind DNA and control the transcription of target genes, influencing processes such as cell proliferation and neuronal development. This gene is particularly important for normal neural and muscle cell function and has been implicated in neurodevelopmental disorders and cancer. ZNF609 is known to interact with signaling pathways that control neuron differentiation and migration, and alterations in its expression have been associated with conditions like intellectual disability and developmental delay. Furthermore, ZNF609's role in cancer biology shows its involvement in regulating genes linked to tumor progression and metastasis. Studies on ZNF609 focus on understanding its regulatory mechanisms and potential as a therapeutic target for diseases related to developmental deficits and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Zinc finger protein 609
Gene Aliases: KIAA0295; ZNF609
UniProt ID: (Human) O15014
Entrez Gene ID: (Human) 23060
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