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Invitrogen
Human ZNF707 Control Fragment Recombinant Protein
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Product Details
RP-100482
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
QWEEPWVEDRERPEFQAVQRGPRPGARKSADPKRHCDHPAWAHKKTHVRRERAREGSSFRKGFRLDTDDGQ
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (32%), Rat (32%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60886. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The ZNF707 gene, a member of the zinc-finger protein (ZNF) family, encodes a transcription factor that can significantly influence various cellular processes by binding to DNA and regulating gene expression. Located on chromosome 4q32, zinc-finger proteins like ZNF707 are characterized by their zinc-finger motifs, which enable their interaction with specific DNA sequences. Mutations in ZNF707, such as rs4873815-TT, have been implicated in the tumorigenesis and prognosis of ovarian clear cell adenocarcinoma (Ov-CCA), highlighting its clinical significance in cancer research. Research also suggests that missense mutations in ZNF genes can alter protein-DNA interactions, potentially leading to cancer development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
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