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Product Details
300-51-100UG
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Published species
Bacteria,
Human
Expression System
E. coli
Amino acid sequence
DHYNCVSSGG QCLYSACPIF TKIQGTCYRG KAKCCK
Molecular weight
3.9 kDa
Class
Recombinant
Type
Protein
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
Determined by its ability to chemoattract CD34+ dendritic cells using a concentration range of 100.0-1000.0 ng/ml.
Conjugate
Form
Lyophilized
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
Recombinant Human BD-1 is a 3.9 kDa protein containing 36 amino acid residues.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BD-1; beta defensin 1; Beta-defensin 1; beta-defensin-1; Defensin, beta 1
Gene Aliases: BD1; DEFB-1; DEFB1; DEFB101; HBD1
UniProt ID: (Human) P60022
Entrez Gene ID: (Human) 1672
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