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Invitrogen
Human c-Fos Synthetic Peptide
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Product Details
GSC00001P
Product Specifications
Class
Synthetic
Type
Peptide
Conjugate
Form
Lyophilized
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
GSC00001P is the immunizing peptide for the rabbit antibody to cFos (OSR00004W & OSC00007W).
GSC00001P may be used as a control in various immunology applications.
Reconstitute with PBS or distilled water.
Store antibody at 4°C up to 12 months. After reconstitution, store at -20°C. Avoid freeze and thaw cycles.
Target Information
FBJ murine osteosarcoma viral oncogene homolog is commonly known as Cellular protooncogene Fos (c-Fos). It belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14. c-Fos heterodimerizes with c-Jun to form the Activator Protein -1 (AP-1) transcription factor which regulates transcription of several genes that play an important role in cellular signal transduction, cell proliferation and differentiation. c-Fos has been shown to be phosphorylated by various stimuli including growth factors and insulin at atleast seven different sites. The best known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK which regulates localization of c-Fos to the nucleus and is thus important for c-Fos induced transcriptional activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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