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Invitrogen
Mouse BMAL1 (aa 582-594) Synthetic Peptide
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Product Details
PEP-075
Product Specifications
Class
Synthetic
Type
Peptide
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
50 µg
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
PEP-075 is a 13 amino acid synthetic peptide whose sequence corresponds to residues 582-594 of mouse BMAL-1 with an amino terminal cysteine added for carrier protein conjugation. The sequence of this peptide is (amino to carboxy terminus): (C)-D582-M-I-D-N-D-Q-G-S-S-S-P-S594
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and mouse BMAL-1, catalog # PA1-523. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
Target Information
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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