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Gibco
Mouse BMP-7 Recombinant Protein, PeproTech®
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Product Details
315-43-10UG
Applications
Tested Dilution
Publications
Product Specifications
Species
Mouse
Expression System
CHO cells
Amino acid sequence
STGGKQRSQN RSKTPKNQEA LRMASVAENS SSDQRQACKK HELYVSFRDL GWQDWIIAPE GYAAYYCEGE CAFPLNSYMN ATNHAIVQTL VHFINPDTVP KPCCAPTQLN AISVLYFDDS SNVILKKYRN MVVRACGCH
Molecular weight
31.5 kDa
Class
Recombinant
Type
Protein
Purity
≥ 95% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
Determined by its ability to induce alkaline phosphatase production by ADTC-5 cells.
Conjugate
Form
Lyophilized
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
Recombinant Mouse BMP-7 is a 31.5 kDa disulfide-linked homodimeric protein consisting of two idential 139 amino acid chains.
Target Information
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
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Bioinformatics
Protein Aliases: BMP; BMP-7; Bone morphogenetic protein; Bone morphogenetic protein 7; OP-1; Osteogenic protein 1; RP11-560A15.5
Gene Aliases: Bmp-7; Bmp7; OP1
UniProt ID: (Mouse) P23359
Entrez Gene ID: (Mouse) 12162
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