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Gibco
Mouse CCL8 (MCP-2) Recombinant Protein
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Product Details
PMC1104
Product Specifications
Species
Mouse
Expression System
E. coli
Amino acid sequence
Mouse CCL8 recombinant protein contains 74 amino acids
Molecular weight
8.5 kDa
Class
Recombinant
Type
Protein
Purity
>98% by SDS-PAGE
Endotoxin concentration
<0.1 ng/µg
Activity
ED50 = 10 - 100 ng/mL; determined by the dose-dependent chemotaxis of human PBMCs.
Conjugate
Form
Lyophilized
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Wet or Dry ice (international)
Product Specific Information
Carrier-Free
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in aqueous buffers supplemented with carrier protein, such as 0.1-1.0% BSA.
Storage: This lyophilized preparation is stable at 2°C to 8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2°C to 8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C. Avoid repeated freeze/thaw cycles.
Target Information
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-C motif chemokine 8; MCP-2; Monocyte chemoattractant protein 2; monocyte chemoattractant protein-2; Monocyte chemotactic protein 2; small inducible cytokine A8; Small-inducible cytokine A8
Gene Aliases: 1810063B20Rik; AB023418; Ccl8; HC14; MCP-2; Mcp2; Scya8
UniProt ID: (Mouse) Q9Z121
Entrez Gene ID: (Mouse) 20307
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