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Gibco
Mouse CXCL10 (IP-10) Recombinant Protein, PeproTech®
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Product Details
250-16-25UG
Applications
Tested Dilution
Publications
Product Specifications
Species
Mouse
Published species
Bacteria,
Human,
Mouse,
Non-human primate,
Rabbit,
Rat
Expression System
E. coli
Amino acid sequence
IPLARTVRCN CIHIDDGPVR MRAIGKLEII PASLSCPRVE IIATMKKNDE QRCLNPESKT IKNLMKAFSQ KRSKRAP
Molecular weight
8.7 kDa
Class
Recombinant
Type
Protein
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
Assay 1: Determined by its ability to chemoattract IL-2 activated T cells using a concentration range of 0.1-10.0 ng/ml. Assay 2: Determined by its ability to chemoattract CXCR3-transfected HEK293 cells using a concentration range of 100-500 ng/ml.
Conjugate
Form
Lyophilized
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
Recombinant Murine IP-10 is an 8.7 kDa protein consisting of 77 amino acids, including the four conserved cysteine residues present in CXC chemokines.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
IP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on neutrophils. Its functions include stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis. Mig and IP-10 share the same receptor, CXCR3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 10 kDa interferon gamma-induced protein; C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 10; C7; CC motif chemokine; CCmotif chemokine; CXC; CXC motif chemokine; CXCL; Gamma-IP10; H-IP-10; interferon activated gene 10; Interferon-gamma induced protein CRG-2; interferon-gamma-induced protein CRG-2; M-IP-10; small inducible cytokine B subfamily (Cys-X-Cys), member 10; Small-inducible cytokine B10
Gene Aliases: C7; CRG-2; Crg2; Cxcl10; gIP-10; Ifi10; INP10; IP-10; IP10; mob-1; Scyb10
UniProt ID: (Mouse) P17515
Entrez Gene ID: (Mouse) 15945
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