Product References
Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging.
Nature immunology
Silva-Cayetano A,Fra-Bido S,Robert PA,Innocentin S,Burton AR,Watson EM,Lee JL,Webb LMC,Foster WS,McKenzie RCJ,Bignon A,Vanderleyden I,Alterauge D,Lemos JP,Carr EJ,Hill DL,Cinti I,Balabanian K,Baumjohann D,Espeli M,Meyer-Hermann M,Denton AE,Linterman MA
250-20A was used in In vitro experiments to show that T follicular helper (TFH) cell localization is critical for the quality of the antibody response and for the expansion of the follicular dendritic cells (FDC) network upon immunization.
Sat Jul 01 00:00:00 EDT 2023
Dynamin-2 deficiency causes age- and sex-dependent neutropenia and myelodysplasia in mice.
Blood advances
Willis AJ,Corey SJ,Murga-Zamalloa C,Karimi SS,Khaddour K,Quigley J,Eklund EA,Chen Y
250-20A was used in In vitro experiments to report on conditionally dynamin-2 deleted mice in hematopoietic tissues using the Vav-Cre murine strain. Homozygous Dnm2 deletion in blood tissues is embryonic lethal.
Tue Apr 25 00:00:00 EDT 2023
SDF-1α Promotes Chondrocyte Autophagy through CXCR4/mTOR Signaling Axis.
International journal of molecular sciences
Li J,Chen H,Cai L,Guo D,Zhang D,Zhou X,Xie J
250-20A was used in Cell Culture to investigate the effect of SDF-1α, the most common isoform of stromal cell-derived factor 1, on chondrocyte autophagy and the underlying biomechanism.
Sun Jan 15 00:00:00 EST 2023
Impaired CXCL12 signaling contributes to resistance of pancreatic cancer subpopulations to T cell-mediated cytotoxicity.
Oncoimmunology
Lin YN,Schmidt MO,Sharif GM,Vietsch EE,Kiliti AJ,Barefoot ME,Riegel AT,Wellstein A
250-20A was used in Cell Culture to conclude that reduced CXCL12.
Fri Apr 08 00:00:00 EDT 2022
Functional characterization of the dural sinuses as a neuroimmune interface.
Cell
Rustenhoven J,Drieu A,Mamuladze T,de Lima KA,Dykstra T,Wall M,Papadopoulos Z,Kanamori M,Salvador AF,Baker W,Lemieux M,Da Mesquita S,Cugurra A,Fitzpatrick J,Sviben S,Kossina R,Bayguinov P,Townsend RR,Zhang Q,Erdmann-Gilmore P,Smirnov I,Lopes MB,Herz J,Kipnis J
Thu Feb 18 00:00:00 EST 2021
A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation.
Cancer cell
Lazarian G,Yin S,Ten Hacken E,Sewastianik T,Uduman M,Font-Tello A,Gohil SH,Li S,Kim E,Joyal H,Billington L,Witten E,Zheng M,Huang T,Severgnini M,Lefebvre V,Rassenti LZ,Gutierrez C,Georgopoulos K,Ott CJ,Wang L,Kipps TJ,Burger JA,Livak KJ,Neuberg DS,Baran-Marszak F,Cymbalista F,Carrasco RD,Wu CJ
Mon Mar 08 00:00:00 EST 2021
Efficient homing of antibody-secreting cells to the bone marrow requires RNA-binding protein ZFP36L1.
The Journal of experimental medicine
Saveliev A,Bell SE,Turner M
Mon Mar 01 00:00:00 EST 2021
Intranasal mesenchymal stem cell therapy to boost myelination after encephalopathy of prematurity.
Glia
Vaes JEG,van Kammen CM,Trayford C,van der Toorn A,Ruhwedel T,Benders MJNL,Dijkhuizen RM,Möbius W,van Rijt SH,Nijboer CH
250-20A was used in Cell Culture to show that MSCs adapt their secretome after ex vivo exposure to dWMI milieu and identified several factors including IGF1, EGF, LIF, and IL11 that potently boost OL maturation.
Mon Mar 01 00:00:00 EST 2021
Inhibition of host Ogr1 enhances effector CD8+ T-cell function by modulating acidic microenvironment.
Cancer gene therapy
Cao L,Li W,Yang X,Zhang W,Li M,Zhang H,Qin C,Chen X,Gao R
Mon Nov 01 00:00:00 EDT 2021
SDF-1α/OPF/BP Composites Enhance the Migrating and Osteogenic Abilities of Mesenchymal Stem Cells.
Stem cells international
Li L,Liu X,Gaihre B,Park S,Li Y,Terzic A,Lu L
Fri Aug 27 00:00:00 EDT 2021
SDF-1α/OPF/BP Composites Enhance the Migrating and Osteogenic Abilities of Mesenchymal Stem Cells.
Stem cells international
Li L,Liu X,Gaihre B,Park S,Li Y,Terzic A,Lu L
Fri Aug 27 00:00:00 EDT 2021
Microtubule destabilization is a critical checkpoint of chemotaxis and transendothelial migration in melanoma cells but not in T cells.
Cell adhesion & migration
Roncato F,Regev O,Yadav SK,Alon R
250-20A was used in In vitro experiments to investigate microtubule turnover in epithelial barriers.
Wed Dec 01 00:00:00 EST 2021
A Pillar-Free Diffusion Device for Studying Chemotaxis on Supported Lipid Bilayers.
Micromachines
Hao J,Zhao W,Oh JM,Shen K
250-20A was used in In vitro experiments to engineer a multichannel diffusion device that incorporates a chemoattractant gradient and a supported lipid bilayer (SLB) tethered with membrane-bound factors that mimics stromal cell membranes.
Sat Oct 16 00:00:00 EDT 2021
Met and Cxcr4 cooperate to protect skeletal muscle stem cells against inflammation-induced damage during regeneration.
eLife
Lahmann I,Griger J,Chen JS,Zhang Y,Schuelke M,Birchmeier C
250-20A was used in Cell Culture to conclude that muscle stem cells require MET and CXCR4 to protect them against the harsh inflammatory environment encountered in an acute muscle injury.
Thu Aug 05 00:00:00 EDT 2021
Endothelial STING controls T cell transmigration in an IFNI-dependent manner.
JCI insight
Anastasiou M,Newton GA,Kaur K,Carrillo-Salinas FJ,Smolgovsky SA,Bayer AL,Ilyukha V,Sharma S,Poltorak A,Luscinskas FW,Alcaide P
250-20A was used in In vitro experiments to investigate IFN signalling effect on T cell transdoepithelial infiltration.
Mon Aug 09 00:00:00 EDT 2021
Mevalonate metabolism-dependent protein geranylgeranylation regulates thymocyte egress.
The Journal of experimental medicine
Du X,Zeng H,Liu S,Guy C,Dhungana Y,Neale G,Bergo MO,Chi H
Mon Feb 03 00:00:00 EST 2020
Ubiquitous overexpression of CXCL12 confers radiation protection and enhances mobilization of hematopoietic stem and progenitor cells.
Stem cells (Dayton, Ohio)
Rajendiran S,Smith-Berdan S,Kunz L,Risolino M,Selleri L,Schroeder T,Forsberg EC
Tue Sep 01 00:00:00 EDT 2020
CD62Ldim Neutrophils Specifically Migrate to the Lung and Participate in the Formation of the Pre-Metastatic Niche of Breast Cancer.
Frontiers in oncology
Wang Z,Yang C,Li L,Zhang Z,Pan J,Su K,Chen W,Li J,Qiu F,Huang J
250-20A was used in Sample Prep (FC/FACS) to examine the critical time of the niche formation and detect a novel subset of CD62Ldim neutrophils.
Fri Nov 13 00:00:00 EST 2020
The Tetraspanin CD53 Regulates Early B Cell Development by Promoting IL-7R Signaling.
Journal of immunology (Baltimore, Md. : 1950)
Greenberg ZJ,Monlish DA,Bartnett RL,Yang Y,Shen G,Li W,Bednarski JJ,Schuettpelz LG
Wed Jan 01 00:00:00 EST 2020
Murine Glucocorticoid Receptors Orchestrate B Cell Migration Selectively between Bone Marrow and Blood.
Journal of immunology (Baltimore, Md. : 1950)
Cain DW,Bortner CD,Diaz-Jimenez D,Petrillo MG,Gruver-Yates A,Cidlowski JA
Sat Aug 01 00:00:00 EDT 2020
Arhgap25 Deficiency Leads to Decreased Numbers of Peripheral Blood B Cells and Defective Germinal Center Reactions.
ImmunoHorizons
Lindner SE,Egelston CA,Huard SM,Lee PP,Wang LD
250-20A was used in Sample Preparation (FC/FACS) to investigate the effects of Arhgap25 deficiency in mice on peripheral blood B cell numbers.
Wed May 20 00:00:00 EDT 2020
Antitumor Effects of Anti-Semaphorin 4D Antibody Unravel a Novel Proinvasive Mechanism of Vascular-Targeting Agents.
Cancer research
Zuazo-Gaztelu I,Pàez-Ribes M,Carrasco P,Martín L,Soler A,Martínez-Lozano M,Pons R,Llena J,Palomero L,Graupera M,Casanovas O
250-20A was used in In vitro experiments to demonstrate beneficial antitumor and prosurvival effects of anti-Sema4D antibody but also unravel a novel mechanism of tumor aggressivity.
Tue Oct 15 00:00:00 EDT 2019
Antitumor Effects of Anti-Semaphorin 4D Antibody Unravel a Novel Proinvasive Mechanism of Vascular-Targeting Agents.
Cancer research
Zuazo-Gaztelu I,Pàez-Ribes M,Carrasco P,Martín L,Soler A,Martínez-Lozano M,Pons R,Llena J,Palomero L,Graupera M,Casanovas O
250-20A was used in In vitro experiments to demonstrate beneficial antitumor and prosurvival effects of anti-Sema4D antibody but also unravel a novel mechanism of tumor aggressivity.
Tue Oct 15 00:00:00 EDT 2019
Chemokines as the modulators of endometrial epithelial cells remodelling.
Scientific reports
Złotkowska A,Andronowska A
Tue Sep 10 00:00:00 EDT 2019
Chemokines as the modulators of endometrial epithelial cells remodelling.
Scientific reports
Złotkowska A,Andronowska A
Tue Sep 10 00:00:00 EDT 2019
CXCR7 promotes melanoma tumorigenesis via Src kinase signaling.
Cell death & disease
Xu S,Tang J,Wang C,Liu J,Fu Y,Luo Y
Mon Feb 25 00:00:00 EST 2019
CCL21/CCR7 axis regulating juvenile cartilage repair can enhance cartilage healing in adults.
Scientific reports
Joutoku Z,Onodera T,Matsuoka M,Homan K,Momma D,Baba R,Hontani K,Hamasaki M,Matsubara S,Hishimura R,Iwasaki N
Tue Mar 26 00:00:00 EDT 2019
CXCL12-CXCR4 pathway activates brown adipocytes and induces insulin resistance in CXCR4-deficient mice under high-fat diet.
Scientific reports
Kurita K,Ishikawa K,Takeda K,Fujimoto M,Ono H,Kumagai J,Inoue H,Yokoh H,Yokote K
Tue Apr 16 00:00:00 EDT 2019
The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+ T cells.
The Journal of experimental medicine
Moalli F,Ficht X,Germann P,Vladymyrov M,Stolp B,de Vries I,Lyck R,Balmer J,Fiocchi A,Kreutzfeldt M,Merkler D,Iannacone M,Ariga A,Stoffel MH,Sharpe J,Bähler M,Sixt M,Diz-Muñoz A,Stein JV
Mon Jul 02 00:00:00 EDT 2018
MicroRNA-155 Modulates Acute Graft-versus-Host Disease by Impacting T Cell Expansion, Migration, and Effector Function.
Journal of immunology (Baltimore, Md. : 1950)
Zitzer NC,Snyder K,Meng X,Taylor PA,Efebera YA,Devine SM,Blazar BR,Garzon R,Ranganathan P
Fri Jun 15 00:00:00 EDT 2018
Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis.
Nature communications
Campa CC,Silva RL,Margaria JP,Pirali T,Mattos MS,Kraemer LR,Reis DC,Grosa G,Copperi F,Dalmarco EM,Lima-Júnior RCP,Aprile S,Sala V,Dal Bello F,Prado DS,Alves-Filho JC,Medana C,Cassali GD,Tron GC,Teixeira MM,Ciraolo E,Russo RC,Hirsch E
Wed Dec 12 00:00:00 EST 2018
Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.
Nature communications
Ishihara J,Ishihara A,Fukunaga K,Sasaki K,White MJV,Briquez PS,Hubbell JA
Mon Jun 04 00:00:00 EDT 2018
Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.
Nature communications
Ishihara J,Ishihara A,Fukunaga K,Sasaki K,White MJV,Briquez PS,Hubbell JA
Mon Jun 04 00:00:00 EDT 2018
Physiological function of phospholipase D2 in anti-tumor immunity: regulation of CD8+ T lymphocyte proliferation.
Scientific reports
Ngo Thai Bich V,Hongu T,Miura Y,Katagiri N,Ohbayashi N,Yamashita-Kanemaru Y,Shibuya A,Funakoshi Y,Kanaho Y
Thu Apr 19 00:00:00 EDT 2018
Migrating Myeloid Cells Sense Temporal Dynamics of Chemoattractant Concentrations.
Immunity
Petrie Aronin CE,Zhao YM,Yoon JS,Morgan NY,Prüstel T,Germain RN,Meier-Schellersheim M
Tue Nov 21 00:00:00 EST 2017
The cell polarity determinant CDC42 controls division symmetry to block leukemia cell differentiation.
Blood
Mizukawa B,O'Brien E,Moreira DC,Wunderlich M,Hochstetler CL,Duan X,Liu W,Orr E,Grimes HL,Mulloy JC,Zheng Y
Thu Sep 14 00:00:00 EDT 2017
Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression.
The Journal of experimental medicine
Kim E,Cheng Y,Bolton-Gillespie E,Cai X,Ma C,Tarangelo A,Le L,Jambhekar M,Raman P,Hayer KE,Wertheim G,Speck NA,Tong W,Viatour P
Mon Jul 03 00:00:00 EDT 2017
Generation of an osteoblast-based artificial niche that supports in vitro B lymphopoiesis.
Experimental & molecular medicine
Yu J,Choi S,Kim H,Lee N,Yun H,Kim S,Jeong ST,Rho J
Fri Nov 24 00:00:00 EST 2017
An Anti-Inflammatory Role for NLRP10 in Murine Cutaneous Leishmaniasis.
Journal of immunology (Baltimore, Md. : 1950)
Clay GM,Valadares DG,Graff JW,Ulland TK,Davis RE,Scorza BM,Zhanbolat BS,Chen Y,Sutterwala FS,Wilson ME
Sun Oct 15 00:00:00 EDT 2017
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
Scientific reports
Singh K,Davies G,Alenazi Y,Eaton JRO,Kawamura A,Bhattacharya S
Tue Jun 27 00:00:00 EDT 2017
STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells.
Nature communications
Nunes-Hasler P,Maschalidi S,Lippens C,Castelbou C,Bouvet S,Guido D,Bermont F,Bassoy EY,Page N,Merkler D,Hugues S,Martinvalet D,Manoury B,Demaurex N
Fri Nov 24 00:00:00 EST 2017
GNA13 loss in germinal center B cells leads to impaired apoptosis and promotes lymphoma in vivo.
Blood
Healy JA,Nugent A,Rempel RE,Moffitt AB,Davis NS,Jiang X,Shingleton JR,Zhang J,Love C,Datta J,McKinney ME,Tzeng TJ,Wettschureck N,Offermanns S,Walzer KA,Chi JT,Rasheed SA,Casey PJ,Lossos IS,Dave SS
Thu Jun 02 00:00:00 EDT 2016
AKT Signaling Prevailing in Mesenchymal Stromal Cells Modulates the Functionality of Hematopoietic Stem Cells via Intercellular Communication.
Stem cells (Dayton, Ohio)
Singh S,Moirangthem RD,Vaidya A,Jalnapurkar S,Limaye L,Kale V
Thu Sep 01 00:00:00 EDT 2016
Rac GTPase Activating Protein ARHGAP25 Regulates Leukocyte Transendothelial Migration in Mice.
Journal of immunology (Baltimore, Md. : 1950)
Csépányi-Kömi R,Wisniewski É,Bartos B,Lévai P,Németh T,Balázs B,Kurz AR,Bierschenk S,Sperandio M,Ligeti E
Sat Oct 01 00:00:00 EDT 2016
Ptk7-Deficient Mice Have Decreased Hematopoietic Stem Cell Pools as a Result of Deregulated Proliferation and Migration.
Journal of immunology (Baltimore, Md. : 1950)
Lhoumeau AC,Arcangeli ML,De Grandis M,Giordano M,Orsoni JC,Lembo F,Bardin F,Marchetto S,Aurrand-Lions M,Borg JP
Sun May 15 00:00:00 EDT 2016
Roles of endothelial A-type lamins in migration of T cells on and under endothelial layers.
Scientific reports
Song KH,Lee J,Park H,Kim HM,Park J,Kwon KW,Doh J
Mon Mar 21 00:00:00 EDT 2016
Overexpression of soluble RAGE in mesenchymal stem cells enhances their immunoregulatory potential for cellular therapy in autoimmune arthritis.
Scientific reports
Park MJ,Lee SH,Moon SJ,Lee JA,Lee EJ,Kim EK,Park JS,Lee J,Min JK,Kim SJ,Park SH,Cho ML
Wed Nov 02 00:00:00 EDT 2016
Roles of the mitochondrial Na(+)-Ca(2+) exchanger, NCLX, in B lymphocyte chemotaxis.
Scientific reports
Kim B,Takeuchi A,Hikida M,Matsuoka S
Wed Jun 22 00:00:00 EDT 2016
PTEN regulates natural killer cell trafficking in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Leong JW,Schneider SE,Sullivan RP,Parikh BA,Anthony BA,Singh A,Jewell BA,Schappe T,Wagner JA,Link DC,Yokoyama WM,Fehniger TA
Tue Feb 17 00:00:00 EST 2015
Asymmetric cell division during T cell development controls downstream fate.
The Journal of cell biology
Pham K,Shimoni R,Charnley M,Ludford-Menting MJ,Hawkins ED,Ramsbottom K,Oliaro J,Izon D,Ting SB,Reynolds J,Lythe G,Molina-Paris C,Melichar H,Robey E,Humbert PO,Gu M,Russell SM
Mon Sep 14 00:00:00 EDT 2015
Endogenous mesenchymal stromal cells in bone marrow are required to preserve muscle function in mdx mice.
Stem cells (Dayton, Ohio)
Fujita R,Tamai K,Aikawa E,Nimura K,Ishino S,Kikuchi Y,Kaneda Y
Sun Mar 01 00:00:00 EST 2015
Engineered mesenchymal stem cells with enhanced tropism and paracrine secretion of cytokines and growth factors to treat traumatic brain injury.
Stem cells (Dayton, Ohio)
Wang Z,Wang Y,Wang Z,Gutkind JS,Wang Z,Wang F,Lu J,Niu G,Teng G,Chen X
Sun Feb 01 00:00:00 EST 2015
Pretreatment of Mesenchymal Stem Cells Manipulates Their Vasculoprotective Potential While Not Altering Their Homing Within the Injured Gut.
Stem cells (Dayton, Ohio)
Kavanagh DP,Suresh S,Newsome PN,Frampton J,Kalia N
Tue Sep 01 00:00:00 EDT 2015
Systemic high-mobility group box 1 administration suppresses skin inflammation by inducing an accumulation of PDGFRα(+) mesenchymal cells from bone marrow.
Scientific reports
Aikawa E,Fujita R,Kikuchi Y,Kaneda Y,Tamai K
Fri Jun 05 00:00:00 EDT 2015
Contribution and Mobilization of Mesenchymal Stem Cells in a mouse model of carbon tetrachloride-induced liver fibrosis.
Scientific reports
Liu Y,Yang X,Jing Y,Zhang S,Zong C,Jiang J,Sun K,Li R,Gao L,Zhao X,Wu D,Shi Y,Han Z,Wei L
Tue Dec 08 00:00:00 EST 2015
Contribution and Mobilization of Mesenchymal Stem Cells in a mouse model of carbon tetrachloride-induced liver fibrosis.
Scientific reports
Liu Y,Yang X,Jing Y,Zhang S,Zong C,Jiang J,Sun K,Li R,Gao L,Zhao X,Wu D,Shi Y,Han Z,Wei L
Tue Dec 08 00:00:00 EST 2015
AKAP9 regulates activation-induced retention of T lymphocytes at sites of inflammation.
Nature communications
Herter JM,Grabie N,Cullere X,Azcutia V,Rosetti F,Bennett P,Herter-Sprie GS,Elyaman W,Luscinskas FW,Lichtman AH,Mayadas TN
Fri Dec 18 00:00:00 EST 2015
SLM produced porous titanium implant improvements for enhanced vascularization and osteoblast seeding.
International journal of molecular sciences
Matena J,Petersen S,Gieseke M,Kampmann A,Teske M,Beyerbach M,Murua Escobar H,Haferkamp H,Gellrich NC,Nolte I
250-20A was used in Cell Culture to evaluate the effectiveness of Selective Laser Melting on vascularization and osteoblast seeding.
Thu Apr 02 00:00:00 EDT 2015
SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury.
Blood
Niswander LM,Fegan KH,Kingsley PD,McGrath KE,Palis J
Thu Jul 10 00:00:00 EDT 2014
SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury.
Blood
Niswander LM,Fegan KH,Kingsley PD,McGrath KE,Palis J
Thu Jul 10 00:00:00 EDT 2014
Profilin 1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrow.
Blood
Zheng J,Lu Z,Kocabas F,Böttcher RT,Costell M,Kang X,Liu X,Deberardinis RJ,Wang Q,Chen GQ,Sadek H,Zhang CC
Thu Feb 13 00:00:00 EST 2014
Sphingosine-1-phosphate receptor 2 is critical for follicular helper T cell retention in germinal centers.
The Journal of experimental medicine
Moriyama S,Takahashi N,Green JA,Hori S,Kubo M,Cyster JG,Okada T
Mon Jun 30 00:00:00 EDT 2014
GPR18 is required for a normal CD8αα intestinal intraepithelial lymphocyte compartment.
The Journal of experimental medicine
Wang X,Sumida H,Cyster JG
Mon Nov 17 00:00:00 EST 2014
Dynamin 2-dependent endocytosis is required for sustained S1PR1 signaling.
The Journal of experimental medicine
Willinger T,Ferguson SM,Pereira JP,De Camilli P,Flavell RA
Mon Apr 07 00:00:00 EDT 2014
Dynamin 2-dependent endocytosis is required for sustained S1PR1 signaling.
The Journal of experimental medicine
Willinger T,Ferguson SM,Pereira JP,De Camilli P,Flavell RA
Mon Apr 07 00:00:00 EDT 2014
Ultrasound-triggered disruption and self-healing of reversibly cross-linked hydrogels for drug delivery and enhanced chemotherapy.
Proceedings of the National Academy of Sciences of the United States of America
Huebsch N,Kearney CJ,Zhao X,Kim J,Cezar CA,Suo Z,Mooney DJ
Tue Jul 08 00:00:00 EDT 2014
Stromal cell derived factor-1α promotes C-Kit+ cardiac stem/progenitor cell quiescence through casein kinase 1α and GSK3β.
Stem cells (Dayton, Ohio)
Dimova N,Wysoczynski M,Rokosh G
Sat Feb 01 00:00:00 EST 2014
Essential role of Elmo1 in Dock2-dependent lymphocyte migration.
Journal of immunology (Baltimore, Md. : 1950)
Stevenson C,de la Rosa G,Anderson CS,Murphy PS,Capece T,Kim M,Elliott MR
Sun Jun 15 00:00:00 EDT 2014
Proprotein convertase FURIN constrains Th2 differentiation and is critical for host resistance against Toxoplasma gondii.
Journal of immunology (Baltimore, Md. : 1950)
Oksanen A,Aittomäki S,Jankovic D,Ortutay Z,Pulkkinen K,Hämäläinen S,Rokka A,Corthals GL,Watford WT,Junttila I,O'Shea JJ,Pesu M
Mon Dec 01 00:00:00 EST 2014
CCL2 shapes macrophage polarization by GM-CSF and M-CSF: identification of CCL2/CCR2-dependent gene expression profile.
Journal of immunology (Baltimore, Md. : 1950)
Sierra-Filardi E,Nieto C,Domínguez-Soto A,Barroso R,Sánchez-Mateos P,Puig-Kroger A,López-Bravo M,Joven J,Ardavín C,Rodríguez-Fernández JL,Sánchez-Torres C,Mellado M,Corbí AL
Tue Apr 15 00:00:00 EDT 2014
MIF promotes B cell chemotaxis through the receptors CXCR4 and CD74 and ZAP-70 signaling.
Journal of immunology (Baltimore, Md. : 1950)
Klasen C,Ohl K,Sternkopf M,Shachar I,Schmitz C,Heussen N,Hobeika E,Levit-Zerdoun E,Tenbrock K,Reth M,Bernhagen J,El Bounkari O
Sun Jun 01 00:00:00 EDT 2014
FGF-23 is a negative regulator of prenatal and postnatal erythropoiesis.
The Journal of biological chemistry
Coe LM,Madathil SV,Casu C,Lanske B,Rivella S,Sitara D
Fri Apr 04 00:00:00 EDT 2014
Deletion of Fgfr1 in osteoblasts enhances mobilization of EPCs into peripheral blood in a mouse endotoxemia model.
International journal of biological sciences
Zhang Y,Su N,Luo F,Wen X,Tang Y,Yang J,Chen S,Jiang W,Du X,Chen L
Fri May 15 00:00:00 EDT 2015
Ovulation and extra-ovarian origin of ovarian cancer.
Scientific reports
Yang-Hartwich Y,Gurrea-Soteras M,Sumi N,Joo WD,Holmberg JC,Craveiro V,Alvero AB,Mor G
Tue Aug 19 00:00:00 EDT 2014
The nucleotide sugar UDP-glucose mobilizes long-term repopulating primitive hematopoietic cells.
The Journal of clinical investigation
Kook S,Cho J,Lee SB,Lee BC
Thu Aug 01 00:00:00 EDT 2013
GSK3β regulates physiological migration of stem/progenitor cells via cytoskeletal rearrangement.
The Journal of clinical investigation
Lapid K,Itkin T,D'Uva G,Ovadya Y,Ludin A,Caglio G,Kalinkovich A,Golan K,Porat Z,Zollo M,Lapidot T
Mon Apr 01 00:00:00 EDT 2013
The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor.
Leukemia
Karpova D,Dauber K,Spohn G,Chudziak D,Wiercinska E,Schulz M,Pettit AR,Levesque JP,Romagnoli B,Patel K,Chevalier E,Dembowsky K,Bonig H
Sun Dec 01 00:00:00 EST 2013
CXCL9 causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation.
Journal of immunology (Baltimore, Md. : 1950)
Giegold O,Ogrissek N,Richter C,Schröder M,Herrero San Juan M,Pfeilschifter JM,Radeke HH
Mon Apr 01 00:00:00 EDT 2013
IL-27 receptor signaling regulates CD4+ T cell chemotactic responses during infection.
Journal of immunology (Baltimore, Md. : 1950)
Gwyer Findlay E,Villegas-Mendez A,de Souza JB,Inkson CA,Shaw TN,Saris CJ,Hunter CA,Riley EM,Couper KN
Wed May 01 00:00:00 EDT 2013
CD2-associated protein regulates plasmacytoid dendritic cell migration, but is dispensable for their development and cytokine production.
Journal of immunology (Baltimore, Md. : 1950)
Srivatsan S,Swiecki M,Otero K,Cella M,Shaw AS
Sun Dec 15 00:00:00 EST 2013
Aurintricarboxylic acid ameliorates experimental autoimmune encephalomyelitis by blocking chemokine-mediated pathogenic cell migration and infiltration.
Journal of immunology (Baltimore, Md. : 1950)
Zhang F,Wei W,Chai H,Xie X
Fri Feb 01 00:00:00 EST 2013
Integrin-α FG-GAP repeat-containing protein 2 is critical for normal B cell differentiation and controls disease development in a lupus model.
Journal of immunology (Baltimore, Md. : 1950)
Al-Shami A,Crisostomo J,Wilkins C,Xu N,Humphries J,Chang WC,Anderson SJ,Oravecz T
Tue Oct 01 00:00:00 EDT 2013
RasGRP1, but not RasGRP3, is required for efficient thymic β-selection and ERK activation downstream of CXCR4.
PloS one
Golec DP,Dower NA,Stone JC,Baldwin TA
Mon Jul 01 00:00:00 EDT 2013
The decreased metastatic potential of rhabdomyosarcoma cells obtained through MET receptor downregulation and the induction of differentiation.
Cell death & disease
Miekus K,Lukasiewicz E,Jarocha D,Sekula M,Drabik G,Majka M
Thu Jan 17 00:00:00 EST 2013
SDF-1 promotes endochondral bone repair during fracture healing at the traumatic brain injury condition.
PloS one
Liu X,Zhou C,Li Y,Ji Y,Xu G,Wang X,Yan J
Wed Jul 24 00:00:00 EDT 2013
A PK2/Bv8/PROK2 antagonist suppresses tumorigenic processes by inhibiting angiogenesis in glioma and blocking myeloid cell infiltration in pancreatic cancer.
PloS one
Curtis VF,Wang H,Yang P,McLendon RE,Li X,Zhou QY,Wang XF
Fri Jul 26 00:00:00 EDT 2013
Calcium- and integrin-binding protein 1 regulates megakaryocyte ploidy, adhesion, and migration.
Blood
Kostyak JC,Naik MU,Naik UP
Thu Jan 19 00:00:00 EST 2012
RhoH is critical for cell-microenvironment interactions in chronic lymphocytic leukemia in mice and humans.
Blood
Troeger A,Johnson AJ,Wood J,Blum WG,Andritsos LA,Byrd JC,Williams DA
Thu May 17 00:00:00 EDT 2012
MT1-MMP plays a critical role in hematopoiesis by regulating HIF-mediated chemokine/cytokine gene transcription within niche cells.
Blood
Nishida C,Kusubata K,Tashiro Y,Gritli I,Sato A,Ohki-Koizumi M,Morita Y,Nagano M,Sakamoto T,Koshikawa N,Kuchimaru T,Kizaka-Kondoh S,Seiki M,Nakauchi H,Heissig B,Hattori K
Thu Jun 07 00:00:00 EDT 2012
Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice.
Blood
Liu Y,Belkina NV,Park C,Nambiar R,Loughhead SM,Patino-Lopez G,Ben-Aissa K,Hao JJ,Kruhlak MJ,Qi H,von Andrian UH,Kehrl JH,Tyska MJ,Shaw S
Thu Jan 12 00:00:00 EST 2012
Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels.
The Journal of experimental medicine
Hyun YM,Sumagin R,Sarangi PP,Lomakina E,Overstreet MG,Baker CM,Fowell DJ,Waugh RE,Sarelius IH,Kim M
Mon Jul 02 00:00:00 EDT 2012
High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.
The Journal of experimental medicine
Yang D,Postnikov YV,Li Y,Tewary P,de la Rosa G,Wei F,Klinman D,Gioannini T,Weiss JP,Furusawa T,Bustin M,Oppenheim JJ
Mon Jan 16 00:00:00 EST 2012
L-selectin and SDF-1 enhance the migration of mouse and human cardiac mesoangioblasts.
Cell death and differentiation
Bernal A,San Martín N,Fernández M,Covarello D,Molla F,Soldo A,Latini R,Cossu G,Gálvez BG
Wed Feb 01 00:00:00 EST 2012
Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Dalli J,Jones CP,Cavalcanti DM,Farsky SH,Perretti M,Rankin SM
Sun Jan 01 00:00:00 EST 2012
Signaling through L-selectin mediates enhanced chemotaxis of lymphocyte subsets to secondary lymphoid tissue chemokine.
Journal of immunology (Baltimore, Md. : 1950)
Subramanian H,Grailer JJ,Ohlrich KC,Rymaszewski AL,Loppnow JJ,Kodera M,Conway RM,Steeber DA
Sun Apr 01 00:00:00 EDT 2012
A novel NKR-P1B(bright) NK cell subset expresses an activated CD25(+)CX(3)CR1(+)CD62L(-)CD11b(-)CD27(-) phenotype and is prevalent in blood, liver, and gut-associated lymphoid organs of rats.
Journal of immunology (Baltimore, Md. : 1950)
Inngjerdingen M,Kveberg L,Vaage JT
Thu Mar 15 00:00:00 EDT 2012
Difference in Th1 and Th17 lymphocyte adhesion to endothelium.
Journal of immunology (Baltimore, Md. : 1950)
Alcaide P,Maganto-Garcia E,Newton G,Travers R,Croce KJ,Bu DX,Luscinskas FW,Lichtman AH
Wed Feb 01 00:00:00 EST 2012
The IKKα-dependent NF-κB p52/RelB noncanonical pathway is essential to sustain a CXCL12 autocrine loop in cells migrating in response to HMGB1.
Journal of immunology (Baltimore, Md. : 1950)
Kew RR,Penzo M,Habiel DM,Marcu KB
Thu Mar 01 00:00:00 EST 2012
Optimal population of FoxP3+ T cells in tumors requires an antigen priming-dependent trafficking receptor switch.
PloS one
Wang C,Lee JH,Kim CH
Mon Jun 04 00:00:00 EDT 2012
Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells.
Nature immunology
Islam SA,Chang DS,Colvin RA,Byrne MH,McCully ML,Moser B,Lira SA,Charo IF,Luster AD
Tue Feb 01 00:00:00 EST 2011
Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation.
Blood
Mazharian A,Ghevaert C,Zhang L,Massberg S,Watson SP
Thu May 12 00:00:00 EDT 2011
Adult human circulating CD34⁻Lin⁻CD45⁻CD133⁻ cells can differentiate into hematopoietic and endothelial cells.
Blood
Ciraci E,Della Bella S,Salvucci O,Rofani C,Segarra M,Bason C,Molinari A,Maric D,Tosato G,Berardi AC
Thu Aug 25 00:00:00 EDT 2011
Pharmacologic modulation of the calcium-sensing receptor enhances hematopoietic stem cell lodgment in the adult bone marrow.
Blood
Lam BS,Cunningham C,Adams GB
Thu Jan 27 00:00:00 EST 2011
Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche.
The Journal of experimental medicine
Chow A,Lucas D,Hidalgo A,Méndez-Ferrer S,Hashimoto D,Scheiermann C,Battista M,Leboeuf M,Prophete C,van Rooijen N,Tanaka M,Merad M,Frenette PS
Mon Feb 14 00:00:00 EST 2011
Growth-factor receptor-bound protein-2 (Grb2) signaling in B cells controls lymphoid follicle organization and germinal center reaction.
Proceedings of the National Academy of Sciences of the United States of America
Jang IK,Cronshaw DG,Xie LK,Fang G,Zhang J,Oh H,Fu YX,Gu H,Zou Y
Tue May 10 00:00:00 EDT 2011
SOCS3 deletion in B cells alters cytokine responses and germinal center output.
Journal of immunology (Baltimore, Md. : 1950)
Jones SA,White CA,Robb L,Alexander WS,Tarlinton DM
Thu Dec 15 00:00:00 EST 2011
EBI2 guides serial movements of activated B cells and ligand activity is detectable in lymphoid and nonlymphoid tissues.
Journal of immunology (Baltimore, Md. : 1950)
Kelly LM,Pereira JP,Yi T,Xu Y,Cyster JG
Thu Sep 15 00:00:00 EDT 2011
Hematopoietic lineage cell-specific protein 1 functions in concert with the Wiskott-Aldrich syndrome protein to promote podosome array organization and chemotaxis in dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Dehring DA,Clarke F,Ricart BG,Huang Y,Gomez TS,Williamson EK,Hammer DA,Billadeau DD,Argon Y,Burkhardt JK
Fri Apr 15 00:00:00 EDT 2011
Dendritic cells distinguish individual chemokine signals through CCR7 and CXCR4.
Journal of immunology (Baltimore, Md. : 1950)
Ricart BG,John B,Lee D,Hunter CA,Hammer DA
Sat Jan 01 00:00:00 EST 2011
In vivo analysis of uropod function during physiological T cell trafficking.
Journal of immunology (Baltimore, Md. : 1950)
Soriano SF,Hons M,Schumann K,Kumar V,Dennier TJ,Lyck R,Sixt M,Stein JV
Thu Sep 01 00:00:00 EDT 2011
Distinct roles of Cdc42 in thymopoiesis and effector and memory T cell differentiation.
PloS one
Guo F,Zhang S,Tripathi P,Mattner J,Phelan J,Sproles A,Mo J,Wills-Karp M,Grimes HL,Hildeman D,Zheng Y
Thu Mar 24 00:00:00 EDT 2011
Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activation.
PloS one
Roney KE,O'Connor BP,Wen H,Holl EK,Guthrie EH,Davis BK,Jones SW,Jha S,Sharek L,Garcia-Mata R,Bear JE,Ting JP
Thu Mar 01 00:00:00 EST 2012
microRNA-150 regulates mobilization and migration of bone marrow-derived mononuclear cells by targeting Cxcr4.
PloS one
Tano N,Kim HW,Ashraf M
Tue Feb 28 00:00:00 EST 2012
Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion.
PloS one
Nasser MW,Qamri Z,Deol YS,Smith D,Shilo K,Zou X,Ganju RK
Tue Feb 14 00:00:00 EST 2012
The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor.
Immunity
Treanor B,Depoil D,Gonzalez-Granja A,Barral P,Weber M,Dushek O,Bruckbauer A,Batista FD
Fri Feb 26 00:00:00 EST 2010
HS1 has a central role in the trafficking and homing of leukemic B cells.
Blood
Scielzo C,Bertilaccio MT,Simonetti G,Dagklis A,ten Hacken E,Fazi C,Muzio M,Caiolfa V,Kitamura D,Restuccia U,Bachi A,Rocchi M,Ponzoni M,Ghia P,Caligaris-Cappio F
Thu Nov 04 00:00:00 EDT 2010
STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF-induced CXCR2 expression and via modulation of CXCR2 signal transduction.
Blood
Nguyen-Jackson H,Panopoulos AD,Zhang H,Li HS,Watowich SS
Thu Apr 22 00:00:00 EDT 2010
Critical role of Src-Syk-PLC{gamma}2 signaling in megakaryocyte migration and thrombopoiesis.
Blood
Mazharian A,Thomas SG,Dhanjal TS,Buckley CD,Watson SP
Thu Aug 05 00:00:00 EDT 2010
Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4.
The Journal of experimental medicine
Janas ML,Varano G,Gudmundsson K,Noda M,Nagasawa T,Turner M
Mon Jan 18 00:00:00 EST 2010
Vascular Robo4 restricts proangiogenic VEGF signaling in breast.
Proceedings of the National Academy of Sciences of the United States of America
Marlow R,Binnewies M,Sorensen LK,Monica SD,Strickland P,Forsberg EC,Li DY,Hinck L
Tue Jun 08 00:00:00 EDT 2010
CD45 regulates migration, proliferation, and progression of double negative 1 thymocytes.
Journal of immunology (Baltimore, Md. : 1950)
Lai JC,Wlodarska M,Liu DJ,Abraham N,Johnson P
Sun Aug 15 00:00:00 EDT 2010
Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity.
Journal of immunology (Baltimore, Md. : 1950)
Arthur JC,Lich JD,Ye Z,Allen IC,Gris D,Wilson JE,Schneider M,Roney KE,O'Connor BP,Moore CB,Morrison A,Sutterwala FS,Bertin J,Koller BH,Liu Z,Ting JP
Fri Oct 15 00:00:00 EDT 2010
The adaptor protein Sh2d3c is critical for marginal zone B cell development and function.
Journal of immunology (Baltimore, Md. : 1950)
Al-Shami A,Wilkins C,Crisostomo J,Seshasayee D,Martin F,Xu N,Suwanichkul A,Anderson SJ,Oravecz T
Thu Jul 01 00:00:00 EDT 2010
Differential localization of effector and memory CD8 T cell subsets in lymphoid organs during acute viral infection.
Journal of immunology (Baltimore, Md. : 1950)
Jung YW,Rutishauser RL,Joshi NS,Haberman AM,Kaech SM
Mon Nov 01 00:00:00 EDT 2010
An essential role of the cytoplasmic tail of CXCR4 in G-protein signaling and organogenesis.
PloS one
Cronshaw DG,Nie Y,Waite J,Zou YR
Fri Nov 19 00:00:00 EST 2010
Genomics based analysis of interactions between developing B-lymphocytes and stromal cells reveal complex interactions and two-way communication.
BMC genomics
Zetterblad J,Qian H,Zandi S,Månsson R,Lagergren A,Hansson F,Bryder D,Paulsson N,Sigvardsson M
Fri Feb 12 00:00:00 EST 2010
CXCL12-mediated guidance of migrating embryonic stem cell-derived neural progenitors transplanted into the hippocampus.
PloS one
Hartman NW,Carpentino JE,LaMonica K,Mor DE,Naegele JR,Grabel L
Fri Dec 31 00:00:00 EST 2010
T cell specific adapter protein (TSAd) interacts with Tec kinase ITK to promote CXCL12 induced migration of human and murine T cells.
PloS one
Berge T,Sundvold-Gjerstad V,Granum S,Andersen TC,Holthe GB,Claesson-Welsh L,Andreotti AH,Inngjerdingen M,Spurkland A
Thu Mar 18 00:00:00 EDT 2010
Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow.
Nature
Adams GB,Alley IR,Chung UI,Chabner KT,Jeanson NT,Lo Celso C,Marsters ES,Chen M,Weinstein LS,Lin CP,Kronenberg HM,Scadden DT
Thu May 07 00:00:00 EDT 2009
In vivo RNAi screening identifies regulators of actin dynamics as key determinants of lymphoma progression.
Nature genetics
Meacham CE,Ho EE,Dubrovsky E,Gertler FB,Hemann MT
Thu Oct 01 00:00:00 EDT 2009
The Rac activator Tiam1 controls efficient T-cell trafficking and route of transendothelial migration.
Blood
Gérard A,van der Kammen RA,Janssen H,Ellenbroek SI,Collard JG
Thu Jun 11 00:00:00 EDT 2009
T-cell receptor- and CD28-induced Vav1 activity is required for the accumulation of primed T cells into antigenic tissue.
Blood
David R,Ma L,Ivetic A,Takesono A,Ridley AJ,Chai JG,Tybulewicz VL,Marelli-Berg FM
Thu Apr 16 00:00:00 EDT 2009
On the adaptation of endosteal stem cell niche function in response to stress.
Blood
Jiang Y,Bonig H,Ulyanova T,Chang K,Papayannopoulou T
Thu Oct 29 00:00:00 EDT 2009
Rho GTPase Cdc42 is essential for B-lymphocyte development and activation.
Blood
Guo F,Velu CS,Grimes HL,Zheng Y
Thu Oct 01 00:00:00 EDT 2009
Negative regulation of activated alpha-2 integrins during thrombopoiesis.
Blood
Zou Z,Schmaier AA,Cheng L,Mericko P,Dickeson SK,Stricker TP,Santoro SA,Kahn ML
Thu Jun 18 00:00:00 EDT 2009
Activation of Wnt5A signaling is required for CXC chemokine ligand 12-mediated T-cell migration.
Blood
Ghosh MC,Collins GD,Vandanmagsar B,Patel K,Brill M,Carter A,Lustig A,Becker KG,Wood WW,Emeche CD,French AD,O'Connell MP,Xu M,Weeraratna AT,Taub DD
Thu Aug 13 00:00:00 EDT 2009
The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis.
Blood
Senis YA,Tomlinson MG,Ellison S,Mazharian A,Lim J,Zhao Y,Kornerup KN,Auger JM,Thomas SG,Dhanjal T,Kalia N,Zhu JW,Weiss A,Watson SP
Thu May 14 00:00:00 EDT 2009
CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway.
Blood
Gollmer K,Asperti-Boursin F,Tanaka Y,Okkenhaug K,Vanhaesebroeck B,Peterson JR,Fukui Y,Donnadieu E,Stein JV
Thu Jul 16 00:00:00 EDT 2009
Inhibition of the SDF-1alpha-CXCR4 axis by the CXCR4 antagonist AMD3100 suppresses the migration of cultured cells from ATL patients and murine lymphoblastoid cells from HTLV-I Tax transgenic mice.
Blood
Kawaguchi A,Orba Y,Kimura T,Iha H,Ogata M,Tsuji T,Ainai A,Sata T,Okamoto T,Hall WW,Sawa H,Hasegawa H
Thu Oct 01 00:00:00 EDT 2009
CCR6 is required for IL-23-induced psoriasis-like inflammation in mice.
The Journal of clinical investigation
Hedrick MN,Lonsdorf AS,Shirakawa AK,Richard Lee CC,Liao F,Singh SP,Zhang HH,Grinberg A,Love PE,Hwang ST,Farber JM
Sat Aug 01 00:00:00 EDT 2009
T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow.
The Journal of experimental medicine
Jenne CN,Enders A,Rivera R,Watson SR,Bankovich AJ,Pereira JP,Xu Y,Roots CM,Beilke JN,Banerjee A,Reiner SL,Miller SA,Weinmann AS,Goodnow CC,Lanier LL,Cyster JG,Chun J
Mon Oct 26 00:00:00 EDT 2009
LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America
Belkina NV,Liu Y,Hao JJ,Karasuyama H,Shaw S
Tue Mar 24 00:00:00 EDT 2009
p210(Bcr-Abl) desensitizes Cdc42 GTPase signaling for SDF-1alpha-directed migration in chronic myeloid leukemia cells.
Oncogene
Chang YC,Tien SC,Tien HF,Zhang H,Bokoch GM,Chang ZF
Thu Nov 19 00:00:00 EST 2009
Haematopoietic stem cell migration to the ischemic damaged kidney is not altered by manipulating the SDF-1/CXCR4-axis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Stroo I,Stokman G,Teske GJ,Florquin S,Leemans JC
Wed Jul 01 00:00:00 EDT 2009
A cell-intrinsic role for Mst1 in regulating thymocyte egress.
Journal of immunology (Baltimore, Md. : 1950)
Dong Y,Du X,Ye J,Han M,Xu T,Zhuang Y,Tao W
Tue Sep 15 00:00:00 EDT 2009
Control of thymic T cell maturation, deletion and egress by the RNA-binding protein HuR.
Journal of immunology (Baltimore, Md. : 1950)
Papadaki O,Milatos S,Grammenoudi S,Mukherjee N,Keene JD,Kontoyiannis DL
Mon Jun 01 00:00:00 EDT 2009
A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2.
Journal of immunology (Baltimore, Md. : 1950)
Izhak L,Wildbaum G,Zohar Y,Anunu R,Klapper L,Elkeles A,Seagal J,Yefenof E,Ayalon-Soffer M,Karin N
Wed Jul 01 00:00:00 EDT 2009
Cross-presentation by osteoclasts induces FoxP3 in CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Kiesel JR,Buchwald ZS,Aurora R
Fri May 01 00:00:00 EDT 2009
Critical role for ERK1/2 in bone marrow and fetal liver-derived primary megakaryocyte differentiation, motility, and proplatelet formation.
Experimental hematology
Mazharian A,Watson SP,Séverin S
Thu Oct 01 00:00:00 EDT 2009
Notch-RBP-J signaling regulates the mobilization and function of endothelial progenitor cells by dynamic modulation of CXCR4 expression in mice.
PloS one
Wang L,Wang YC,Hu XB,Zhang BF,Dou GR,He F,Gao F,Feng F,Liang YM,Dou KF,Han H
Tue Oct 27 00:00:00 EDT 2009
Stromal cell derived factor-1 enhances bone marrow mononuclear cell migration in mice with acute liver failure.
World journal of gastroenterology
Jin SZ,Meng XW,Han MZ,Sun X,Sun LY,Liu BR
250-20A was used in In vivo experiments to evaluate the number of bone marrow mononuclear cells (BMMC) that are migrated to the liver following transplantation of murine BMMC into mice with acute liver injury.
Sun Jun 07 00:00:00 EDT 2009
T cell receptor-induced phosphoinositide-3-kinase p110delta activity is required for T cell localization to antigenic tissue in mice.
The Journal of clinical investigation
Jarmin SJ,David R,Ma L,Chai JG,Dewchand H,Takesono A,Ridley AJ,Okkenhaug K,Marelli-Berg FM
Sat Mar 01 00:00:00 EST 2008
Structure and function of A41, a vaccinia virus chemokine binding protein.
PLoS pathogens
Bahar MW,Kenyon JC,Putz MM,Abrescia NG,Pease JE,Wise EL,Stuart DI,Smith GL,Grimes JM
Tue Jan 01 00:00:00 EST 2008
Dynamic modulation of CCR7 expression and function on naive T lymphocytes in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Britschgi MR,Link A,Lissandrin TK,Luther SA
Mon Dec 01 00:00:00 EST 2008
CXCL10 blockade protects mice from cyclophosphamide-induced cystitis.
Journal of immune based therapies and vaccines
Sakthivel SK,Singh UP,Singh S,Taub DD,Novakovic KR,Lillard JW
Tue Oct 28 00:00:00 EDT 2008
Inhibition of gluconeogenesis in primary hepatocytes by stromal cell-derived factor-1 (SDF-1) through a c-Src/Akt-dependent signaling pathway.
The Journal of biological chemistry
Liu HY,Wen GB,Han J,Hong T,Zhuo D,Liu Z,Cao W
Fri Nov 07 00:00:00 EST 2008
HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection.
Cell death and differentiation
Kaul M,Ma Q,Medders KE,Desai MK,Lipton SA
Thu Feb 01 00:00:00 EST 2007
Follicular dendritic cell secreted protein (FDC-SP) regulates germinal center and antibody responses.
Journal of immunology (Baltimore, Md. : 1950)
Al-Alwan M,Du Q,Hou S,Nashed B,Fan Y,Yang X,Marshall AJ
Fri Jun 15 00:00:00 EDT 2007
Expression and function of cannabinoid receptors CB1 and CB2 and their cognate cannabinoid ligands in murine embryonic stem cells.
PloS one
Jiang S,Fu Y,Williams J,Wood J,Pandarinathan L,Avraham S,Makriyannis A,Avraham S,Avraham HK
250-20A was used in Cell Culture to study the expression and roles of cannabinoid receptor type 1 (CB1) and cannabinoid receptor type 2 (CB2) and their cognate ligands in embryonic stem (ES) cells and provide insight into cannabinoid system involvement in ES cell survival and hematopoietic differentiation.
Wed Jul 25 00:00:00 EDT 2007
Shedding of syndecan-1 by stromal fibroblasts stimulates human breast cancer cell proliferation via FGF2 activation.
The Journal of biological chemistry
Su G,Blaine SA,Qiao D,Friedl A
Fri May 18 00:00:00 EDT 2007
Lsc regulates marginal-zone B cell migration and adhesion and is required for the IgM T-dependent antibody response.
Immunity
Rubtsov A,Strauch P,Digiacomo A,Hu J,Pelanda R,Torres RM
Tue Nov 01 00:00:00 EST 2005
Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors.
The Journal of experimental medicine
Weller CL,Collington SJ,Brown JK,Miller HR,Al-Kashi A,Clark P,Jose PJ,Hartnell A,Williams TJ
Mon Jun 20 00:00:00 EDT 2005
Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow.
The Journal of experimental medicine
Ueda Y,Kondo M,Kelsoe G
Mon Jun 06 00:00:00 EDT 2005
The role of CXCR2/CXCR2 ligand biological axis in renal cell carcinoma.
Journal of immunology (Baltimore, Md. : 1950)
Mestas J,Burdick MD,Reckamp K,Pantuck A,Figlin RA,Strieter RM
Sat Oct 15 00:00:00 EDT 2005
The neuroblast and angioblast chemotaxic factor SDF-1 (CXCL12) expression is briefly up regulated by reactive astrocytes in brain following neonatal hypoxic-ischemic injury.
BMC neuroscience
Miller JT,Bartley JH,Wimborne HJ,Walker AL,Hess DC,Hill WD,Carroll JE
250-20A was used in Immunohistochemistry to illustrate that while SDF-1 is mainly upregulated via reactive astrocytes following HI injury in neonates, the endogenous chemotaxic factor is only expressed within a brief window-of-time to recruit repartive cells.
Mon Oct 31 00:00:00 EST 2005
Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing.
Immunity
Nombela-Arrieta C,Lacalle RA,Montoya MC,Kunisaki Y,Megías D,Marqués M,Carrera AC,Mañes S,Fukui Y,Martínez-A C,Stein JV
Wed Sep 01 00:00:00 EDT 2004
Cutting edge: Th2 cell trafficking into the allergic lung is dependent on chemoattractant receptor signaling.
Journal of immunology (Baltimore, Md. : 1950)
Mathew A,Medoff BD,Carafone AD,Luster AD
Mon Jul 15 00:00:00 EDT 2002
TNF-alpha mediates SDF-1 alpha-induced NF-kappa B activation and cytotoxic effects in primary astrocytes.
The Journal of clinical investigation
Han Y,He T,Huang DR,Pardo CA,Ransohoff RM
Wed Aug 01 00:00:00 EDT 2001
Enhancement of stromal cell-derived factor-1alpha-induced chemotaxis for CD4/8 double-positive thymocytes by fibronectin and laminin in mice.
Immunology
Yanagawa Y,Iwabuchi K,Onoé K
Sat Sep 01 00:00:00 EDT 2001