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Invitrogen
Mouse EMMPRIN (CD147) His-tag Recombinant Protein
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Product Details
RP-88206
Applications
Tested Dilution
Publications
Product Specifications
Species
Mouse
Expression System
HEK293 cells
Amino acid sequence
Mouse CD147, amino acids Met1-Arg209 (Accession # NP_001070652.1) with a C-terminal His-tag
Tag
His-tag
Molecular weight
21.98 kDa
Class
Recombinant
Type
Protein
Purity
≥ 90% as determined by SDS-PAGE.
Endotoxin concentration
<1.0 EU/µg
Conjugate
Form
Lyophilized
Purification
purified
Storage buffer
PBS, pH 7.4, with 5% mannitol, 5% trehalose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
It is recommended that the protein be aliquoted for optimal storage.
Reconstituted with sterile deionized water to 0.25 mg/mL.
Concentration is measured by UV.
Target Information
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5A11/Basigin; Basic immunoglobulin superfamily; Basigin; CD147; gp 42; HT7 antigen; Membrane glycoprotein gp42; neurothelin
Gene Aliases: AI115436; AI325119; Bsg; CD147; EMMPRIN; HT-7
UniProt ID: (Mouse) P18572
Entrez Gene ID: (Mouse) 12215
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